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Objective To investigate the incidence of macrosomia in Ezhou of Hubei province of China,and analyze the in-fluencing factors in an attempt to provide scientific evidence for the prevention and intervention of macrosomia.Methods The incidence and change pattern of macrosomia were analyzed by reviewing the medical records of delivery between 2010 to 2014 in Maternal and Child Health Hospital of Ezhou City.Chi-square and logistic regression were used to analyze the lnfluencing fac-tors of macrosomia.Results The incidence of macrosomia in Ezhou city was 5.5% in 2010-2014,and it tended to decline by year.Univariate and multivariate analyses revealed that maternal age at delivery,gestational week,history of miscarriage and the infant gender were influencing factors of macrosomia.Conclusion The development of macrosomia is associated with many fac-tors.More attention should be paid to the pregnancy care to reduce the occurrence of macrosomia.

18F-FDG PET-CT is of great significance in non-small cell lung cancer diagnosis, staging, treatment options, efficacy evaluation and prediction of prognosis. But it has non-specificity, and its application is limited. In recent years, a number of new non-18F-FDG imaging agents is constantly developed and used clinically, which contributes to the PET -CT's further development and application in lung cancer.

Objective To investigate the infection characteristics of human cytomegalovirus(HCMV)in infants of Huai′an area . Methods Clinical data of 72 infants with HCMV infection ,diagnosed from Nov .2013 to Feb .2015 ,were retrospectively analyzed , including HCMV DNA level of urine samples ,detected by using fluorescent quantitative‐polymerase chain reaction (FQ‐PCR) ,and complications and clinical characteristics .Results The positive rate of HCMV DNA was 90 .3% (65/72) .Among all of the infected infants ,60 cases (83 .3% ) were with pneumonia ,34 cases(47 .2% ) were with hepatitis ,14 cases(19 .4% ) were with hematological diseases ,3 cases(4 .2% ) were with neurological diseases ,and 28 cases(38 .9% ) were with two or more than two types of complica‐tions .Conclusion FQ‐PCR might be useful for the detection of HCM V infection .Clinical manifestation of pneumonia ,hepatitis ,he‐matological diseases ,and so on might be common in HCMV infected infants .FQ‐PCR ,used to detect HCMV DNA ,could be helpful for the early diagnosis and treatment of HCM V infection .

AIM: To investigate the clinical safety and effectiveness of the two kind of bandage contact lenses: Senofilcon A (Johnson & Johnson Acuvue Oasys) and Balafilcon A ( Bausch& Lomb pure vision ) after laser - assisted subepithelial keratectomy (LASEK).
METHODS: Thirty - eight patients (76 eyes) who had undergone the LASEK were divided into two groups. One group of patients wore Balafilcon A, the other group of patients fitted with Senofilcon A. The lenses were worn continuously for 7d. This was a seven - day experience and the patients scored for the symptom of the eyes (sore eyes, foreign body sensation and tearing) on the third day and the seventh day. Both of the two groups of patients taken off the soft contact lens on the seventh day and let their vision and corneal staining checked.
RESULTS: The symptoms of eye sore and tearing of the two groups patients were different. The patients who wore the Senofilcon A were better. The pain of eyes were also different at 3 and 7d after surgeries(Z = - 4. 146, P =0. 000; Z= - 2. 814, P = 0. 005). The difference on tearing between the two groups at 3 and 7d after surgeries were significant ( Z = -2. 309, P = 0. 021; Z= -3. 276, P= 0. 001). There was no difference on sensation of dryness between the two groups at 3 and 7d after surgeries (Z= -0. 447, P=0. 655; Z= -0. 966, P = 0. 334). After the lenses were taken off, the visual acuity of patients wearing Senofilcon A was better ( t = 3. 800, P = 0. 001 ); corneal staining showed limited spots in 1- 2 quadrants with significant difference (Z= -2. 384,P= 0. 017).
CONCLUSION: The Senofilcon A ( Johnson &Johnson Acuvue Oasys ) and Balafilcon A ( Bausch& Lomb pure vision) bandage contact lenses are safe and effective after LASEK, and the former is better than the latter in epithelial regeneration.

Objective To explore the practicle value of video-electroencephalogram(VEEG)in diagnosis of epilepsy in childhood.Methods One hundred and sixty-six children diagnosed as epilepsy group and 49 children suspected to be epilepsy(suspicious epilepsy group) were monitored with VEEG instrument(PI VEEG 400-C) for 3-4 hours under the state of awaking and sleeping and with all kinds of evoked tests.Results Among 166 cases of epilepsy group,124(74.5%) patients were confirmed as epilepsy,clinical seizures were observed in 26 cases of suspicious epilepsy group,6(23.1%) cases were identified as non-epileptic attacks;Among 49 cases,13((26.5%)) patients were confired as epilepsy,clinical seizures were observed in 16 cases,13(81.3%) cases were identified as non-epileptic attacks.Seizure types were difined in 99 of 137(72.3%) children with epileptic discharges,and epileptic syndromes were defined in 43((30.6%)) of them.Conclusion VEEG can provide accurate and reliable information in diagnosis and classification of epilepsy.

Objective: To establish a method for the determination of loganic acid, chiratin, and loganin in Dipsaci Radix and improve the quality evaluation by analyzing Dipsaci Radix from different habitats. Methods: The analysis was performed on Venusil MP C18 column (250 mm×4.6 mm, 5 μm) with mobile phase consisting of 0.1% H3PO4-acetonitrile for gradient elution: 0-10 min, 8%-9% B; 10-30 min, 9%-11% B; 30-35 min, 11%-100% B. The flow rate was 1 mL/min and the column temperature was 25℃. Results: The results showed that loganic acid, chiratin, and loganin were well separated with the good linearity in 18.4-368.2, 2.02-40.4, and 17.5-349.6 μg/mL, respectively. The average recoveries of the three iridoid glycosides were 99.34%, 99.19%, and 101.61%. Conclusion: Loganic acid, chiratin, and loganin are the main iridoid glycosides in Dipsaci Radix. The method can easily be applied to the content determination of loganic acid, chiratin, and loganin in Dipsaci Radix quickly. The content ranges of loganic acid, chiratin, and loganin are 20.4-186.8, 26.4-177.7, and 1.9-13.2 mg/g, respectively, and the sum of the three iridoid glycosides shows no significant differences in various Dipsaci Radix from different habitats, and proposes to evaluate the quality of Dipsaci Radix.

In the load capacity test of CT diagnosis table top, by analyzing the easy destroy area and related test data for the table top, using a simple mechanical auxiliary support structure in local area of the table top to solve the insufficient loading strength problem of table top and obtain significant results during the actual product usage.
Tomography, X-Ray Computed ; instrumentation ; methods

Objective To investigate the therapeutic effect of ipratropium bromide on bronchial spasm of patients with asthma and chronic obstructive pulmonary disease (COPD).Methods 174 patients with asthma and COPD were selected and divided into two groups, 87 cases in the control group treated with budesonide and formoterol fumarate powder for inhalation , 87 cases in the experimental group received ipratropium bromide on the basis of the control group, pulmonary ventilation function, airway resistance and cytokine levels in induced sputum, the clinical effect and incidence of adverse reactions were compared after the treatment.Results The effective rate in the control group(81.61%)was lower than the experimental group (93.11%), with significant difference (P<0.05); compared with the control group, levels of peak expiratory flow (PEF), maximum midexpiratory flow (MMEF), forced expiratory volume in one second to forced vital capacity ratio (FEV1%), forced vital capacity (FVC) were higher in the experimental group after treatment, levels of airway resistance (Raw), Raw% were lower, level of specific airway conductance (Gsp) was higher after treatment, induced sputum levels of vascular endothelial growth factor (VEGF), intercellular adhesion molecular-1 (ICAM-1), interleukin-13 (IL-13), IL-17 were lower after treatment, with significant difference (P<0.05);there was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The clinical effect of ipratropium bromide in the treatment of asthma and COPD was exactly , ipratropium bromide can significantly improve the pulmonary ventilation function in patients, relieve bronchial spasm, reduce airway resistance, inhibit airway inflammation, and the safety is higher.