1.The association of endocrine-disrupting chemicals exposure, sociodemographic factors, and polycystic ovarian syndrome among reproductive-aged nonpregnant women at the Philippine General Hospital: A case–control study
Erlidia Flores Llamas-Clark ; John Robert Carabeo Medina ; aria Esterlita Tagle Villanueva-Uy ; Francisco M. Heralde III ; Maria Stephanie Fay Samadan Cagayan ; Paulyn Jean Buenaflor Rosell-Ubial ; Michael C. Velarde
Philippine Journal of Obstetrics and Gynecology 2024;48(3):151-161
BACKGROUND:
Polycystic ovarian syndrome (PCOS) is a prevalent condition affecting women of reproductive age, characterized by metabolic, endocrine, and reproductive disturbances including insulin resistance, abnormal uterine bleeding, infertility, and hyperandrogenism, and is associated with diabetes and cardiovascular disease. The etiology of PCOS is unclear and exposure to endocrine-disrupting chemicals (EDCs) present in everyday products may play a role by disrupting hormonal pathways.
OBJECTIVES:
To determine the association between exposure to EDC-containing products, sociodemographic factors, and PCOS diagnosis among nonpregnant reproductive-aged women.
MATERIALS AND METHODS:
A survey assessed the frequency of EDC exposure in homes and workplaces. The Rotterdam Criteria were used for the diagnosis of PCO features with clinical history and ultrasound. The association between PCOS and EDC exposure was determined using Chi-square and logistic regression analysis.
RESULTS:
The study identified significant sociodemographic factors associated with PCOS (P < 0.001) including age, civil status, and household income. Increased likelihood of PCOS was linked to frequent use of scented candles (odds ratio [OR] = 2.07), cleaning sprays (OR = 2.28), and floor polish (OR = 2.07), exposure to new upholstered furniture (OR = 4.00), thermal receipts (OR = 2.16), and consumption of microwaved and processed foods (OR = 2.60), as well as water sourced from wells (OR = 7.69). Additional associations were found with access to public markets (OR = 0.26) and the use of paper food wrappers (OR = 1.72).
CONCLUSION
These findings suggest that frequent exposure to EDC-containing products and certain sociodemographic factors may contribute to the development of PCOS among women of reproductive age. Results underscore the importance of reducing exposure to EDCs to prevent or mitigate the development of PCOS and other reproductive consequences.
Female
2.Evaluation of female infertility
Philippine Journal of Reproductive Endocrinology and Infertility 2007;4(1):19-24
This paper will focus only on the recommendations or guidelines on the evaluation for female infertility. Most of the recommendations were based on the Fertility Assessment and Treatment for People with Fertility Problems Guideline by the National Institute for Clinical Excellence.
Human
;
Female
;
INFERTILITY, FEMALE
3.Malignancies of the female genital organs, 10 years experience a study of incidence and histopathology.
Tae Sung LEE ; Ki Hyun CHO ; Jung Geol AHN ; Hyeong Jong LEE ; Soon Do CHA ; Tak LEE ; Young Wook SUH
Korean Journal of Obstetrics and Gynecology 1991;34(10):1425-1433
No abstract available.
Female
;
Female*
;
Genitalia, Female*
;
Humans
;
Incidence*
4.Conservative Management of Female Incontinence.
International Neurourology Journal 2010;14(4):278-278
5.Sexual Disorders after Menopause.
Journal of the Korean Medical Association 1999;42(2):166-171
No abstract available.
Female
;
Menopause*
7.Women and Their Personalities in the Film.
Journal of the Korean Medical Association 1998;41(2):135-139
8.Combined Xanthogranulomatous Urachitis and Bullous Cystitis: A Case Report.
Ji Eun KWAK ; Han Seong KIM ; Mee JOO ; Sun Hee CHANG ; Sang Hwa SHIM ; Je G CHI ; In Rae CHO
Korean Journal of Pathology 2008;42(1):41-44
Xanthogranulomatous inflammation of the urachus is a very rare benign chronic inflammatory disease of an unknown etiology. Herein we report a case of a 31-year-old woman who complained of lower abdominal pain and dysuria. Cystoscopy revealed a bullous change at the dome of the urinary bladder. MRI revealed a cystic mass above the bladder dome that extended to the umbilicus. A partial cystectomy with urachal resection was performed. Pathological examination revealed xanthogranulomatous urachitis combined with bullous cystitis.
Female
;
Humans
9.A Case of Inflammatory Pseudotumor of the Urinary Biadder.
Hye Rim PARK ; Min Chul LEE ; Nack Kyu CHOI ; Young Euy PARK
Korean Journal of Pathology 1991;25(3):256-262
Inflammatory pseudotumor of the urinary bladder is a proliferative spindle cell lesion that microscopically may suggest a sarcoma but that are benign without a recent history of an operation. The first such case was reported by Roth, in 1980, and thereafter about seven more cases were reported in medical literatures. We reported a case of inflammatory pseudotumor of the urinary bladder mimicking leiomyosarcoma. Patient was a 36-year-old woman with complaint of painless total and gross hematuria for 3 weeks. Partial cystectomy specimen showed a well-demarcated nodular mass of yellow white color, involving the submucosal and muscular layers. Microscopic examination revealed proliferating bundles of spindle cells interspersed with infiltration of many inflammatory cells including eosinophils. Spindle cells were positive for vimentin on immunohistochemistry and corresponding to myofibroblasts on the electron microscopic examination.
Female
;
Humans
10.Female Sexual Dysfunction.
Korean Journal of Andrology 2001;19(3):143-161