1.The association of endocrine-disrupting chemicals exposure, sociodemographic factors, and polycystic ovarian syndrome among reproductive-aged nonpregnant women at the Philippine General Hospital: A case–control study
Erlidia Flores Llamas-Clark ; John Robert Carabeo Medina ; aria Esterlita Tagle Villanueva-Uy ; Francisco M. Heralde III ; Maria Stephanie Fay Samadan Cagayan ; Paulyn Jean Buenaflor Rosell-Ubial ; Michael C. Velarde
Philippine Journal of Obstetrics and Gynecology 2024;48(3):151-161
BACKGROUND:
Polycystic ovarian syndrome (PCOS) is a prevalent condition affecting women of reproductive age, characterized by metabolic, endocrine, and reproductive disturbances including insulin resistance, abnormal uterine bleeding, infertility, and hyperandrogenism, and is associated with diabetes and cardiovascular disease. The etiology of PCOS is unclear and exposure to endocrine-disrupting chemicals (EDCs) present in everyday products may play a role by disrupting hormonal pathways.
OBJECTIVES:
To determine the association between exposure to EDC-containing products, sociodemographic factors, and PCOS diagnosis among nonpregnant reproductive-aged women.
MATERIALS AND METHODS:
A survey assessed the frequency of EDC exposure in homes and workplaces. The Rotterdam Criteria were used for the diagnosis of PCO features with clinical history and ultrasound. The association between PCOS and EDC exposure was determined using Chi-square and logistic regression analysis.
RESULTS:
The study identified significant sociodemographic factors associated with PCOS (P < 0.001) including age, civil status, and household income. Increased likelihood of PCOS was linked to frequent use of scented candles (odds ratio [OR] = 2.07), cleaning sprays (OR = 2.28), and floor polish (OR = 2.07), exposure to new upholstered furniture (OR = 4.00), thermal receipts (OR = 2.16), and consumption of microwaved and processed foods (OR = 2.60), as well as water sourced from wells (OR = 7.69). Additional associations were found with access to public markets (OR = 0.26) and the use of paper food wrappers (OR = 1.72).
CONCLUSION
These findings suggest that frequent exposure to EDC-containing products and certain sociodemographic factors may contribute to the development of PCOS among women of reproductive age. Results underscore the importance of reducing exposure to EDCs to prevent or mitigate the development of PCOS and other reproductive consequences.
Female
2.Evaluation of female infertility
Philippine Journal of Reproductive Endocrinology and Infertility 2007;4(1):19-24
This paper will focus only on the recommendations or guidelines on the evaluation for female infertility. Most of the recommendations were based on the Fertility Assessment and Treatment for People with Fertility Problems Guideline by the National Institute for Clinical Excellence.
Human
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Female
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INFERTILITY, FEMALE
3.Malignancies of the female genital organs, 10 years experience a study of incidence and histopathology.
Tae Sung LEE ; Ki Hyun CHO ; Jung Geol AHN ; Hyeong Jong LEE ; Soon Do CHA ; Tak LEE ; Young Wook SUH
Korean Journal of Obstetrics and Gynecology 1991;34(10):1425-1433
No abstract available.
Female
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Female*
;
Genitalia, Female*
;
Humans
;
Incidence*
4.Giant Cystic Adenomatoid Tumor of the Uterus: A case report.
Young Hee CHOI ; Seoung Wan CHAE ; Hye Kyung AHN ; Min Chul LEE ; Young Euy PARK
Korean Journal of Pathology 1993;27(1):85-87
Adenomatoid tumor of the uterus is a rare benign neoplasm which has been known as mesothelial origin. Characteristically, it appears as a small nodular lesion less than 2.0cm in the myometrium of subserosal region. We describe a case of giant adenomatoid tumor of the uterus having multicystic gross appearance. A 49-year-old woman complained of vaginal bleeding. The tumor was an intramural mass with maximum diameter of 10 cm and located at posterior wall of the uterus. Histologically, the tumor was composed of multiple cystic cavities of variable size lined by flattened cells, lying among thin septa of connective tissue. Immunohistochemically, the cells are positive for low molecular weight cytokeratin(CAM 5.2) and are negative for factor VIII.
Female
;
Humans
5.Primary Transitional Cell Carcinoma of the Ovary: A case report.
Eun Kyung KIM ; Sung Ran HONG ; Jae Uk SHIM ; Hy Sook KIM
Korean Journal of Pathology 1993;27(1):78-80
Primary ovarian transitional cell carcinoma(TCC) is a recently described, distinct subtype of ovarian carcinoma resembling TCC of the urinary bladder. TCC differs from malignant Brenner tumor(MBT) by absence of benign or proliferative Brenner component and prominent stromal calcification. TCC also represents a high-stage tumor with more aggressive biologic behavior than MBT, but it has a relatively favorable response to chemotherapy. TCC may arise from the pluripotential surface epithelium of the ovary or from the cells with urothelial differentiation, rather than from a benign or proliferative Brenner tumor precursors. We report a case of pure form of primary TCC presenting as a left ovarian mass in 45-year-old woman.
Female
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Humans
6.A Case of Recurrent Intestinal Pseudo-obstruction in a Patient with Systemic Lupus Erythematosus.
Yun Jung KIM ; Jeong Ha PARK ; Kyu Sig HWANG ; Sang Cheol BAE
The Journal of the Korean Rheumatism Association 2008;15(1):81-86
Gastrointestinal manifestations are common in systemic lupus erythematosus (SLE). Intestinal pseudo-obstruction (IpO) is a rare, poorly understood and recently recognized gastrointestinal manifestation of SLE. We report a 26-year-old female with SLE for 3 years. 10 months ago, IpO was diagnosed first, and it was responded well to high-dose steroid therapy. After then, oral prednisolone and azathioprine were administered, but the patient had been lost to follow up until recurrence of IpO. She was admitted with diffuse abdominal pain, distension, frequent vomiting, and intermittent dysuria due to recurrent IpO accompanied with bilateral ureterohydronephrosis. Despite of high dose steroid therapy, her symptom and imaging findings were not improved. The patient was treated with pulses of cyclophosphamide, and then the patient's symptoms and signs were gradually subsided. Three weeks following cyclophosphamide therapy, she was able to eat without vomiting and following abdominal CT showed nearly complete resolution of diffuse intestinal distension and bilateral ureterohydronephrosis. High level of awareness of IpO in SLE and appropriate medical treatment is needed to prevent unnecessary surgical treatment. And if this complication is refractory to corticosteroid, active immunosuppressive therapy, such as cyclophosphamide, should be considered.
Female
;
Humans
7.CLINICAL EXPERIENCES WITH PERIAREOLAR REDUCTION MAMMAPLASTY USING CENTRAL PARENTCHYMAL PEDICLE.
Kun Ho LEE ; Jong Han CHO ; Sang Hoon HAN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1162-1170
No abstract available.
Female
;
Mammaplasty*
8.THE COMBINATION OF THE DERMAL PEDICLE WITH CENTRAL PARENCHYMAL PEDICLE IN PERIAREOLAR REDUCTION MAMMAPLASTY.
Kun Ho LEE ; Sang Hoon PARK ; Sang Hoon HAN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1153-1161
No abstract available.
Female
;
Mammaplasty*
9.MASTOPEXY AND REDUCTION MAMMOPLASTY THROUGH THE PERIAREOLAR INCISION.
Bae Won BAE ; So Ra KANG ; Heung Sik PARK ; Chin Ho YOON ; Han Joong KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):1145-1152
No abstract available.
Female
;
Mammaplasty*
10.Malignant Mixed Mullerian Tumor of the Fallopian Tube: Report of a Case.
Eun Deok CHANG ; Young Hee JEE ; Sun Moo KIM
Korean Journal of Pathology 1988;22(1):92-96
Malignant mixed mullerian tumor of the fallopian tube is an extremely rare neoplasm. To date, only 26 cases of primary malignant mixed mullerian tumor of the fallopian tube have been reported, and no report has been published in Korea. This is not surprising, since as a group these meoplasms are least likely to occur in the fallopian tube; the most common sites being the endometrium, vagina, cervix and ovary. We report a case of malignant mixed mullerian tumor of the fallopian tube ina 63-year-old woman with brief review of the literatures.
Female
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Humans