1.Life threatening and occult mediastinal haemorrhage secondary to acquired factor VIII deficiency.
Chieh Suai TAN ; Kenneth P CHAN ; Charles T CHUAH ; Heng Joo NG ; Foong Koon CHEAH ; Felicia S TEO ; Philip C T ENG
Annals of the Academy of Medicine, Singapore 2009;38(3):280-281
Aged
;
Female
;
Hemophilia A
;
complications
;
Hemorrhage
;
etiology
;
Humans
;
Mediastinal Diseases
;
etiology
2.Tetanus in an injecting buprenorphine abuser.
Felicia S W TEO ; Li Yang HSU ; Khim Nian Sin Fai LAM ; A JOHAN
Annals of the Academy of Medicine, Singapore 2007;36(12):1021-1023
INTRODUCTIONInjecting drug abusers are vulnerable to many infectious complications. We describe a case of tetanus in a Singaporean who regularly abused buprenorphine.
CLINICAL PICTUREA 49-year-old male was hospitalised for progressive generalised spasms associated with dysarthria and opisthotonus. Tetanus was diagnosed clinically.
TREATMENTSupportive management was instituted in the intensive care unit (ICU). Toxicology samples tested positive for buprenorphine.
OUTCOMEHe recovered rapidly and was transferred out of the ICU after 8 days. Retrospective questioning confirmed parenteral abuse of buprenorphine.
CONCLUSIONThis case highlights an uncommon and potentially lethal complication of parenteral drug abuse.
Buprenorphine ; Disease Progression ; Dysarthria ; Humans ; Male ; Middle Aged ; Singapore ; Substance Abuse, Intravenous ; Substance-Related Disorders ; complications ; Tetanus ; diagnosis ; etiology ; therapy
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