1.MRI findings in Fukuyama-type congenital muscular dystrophy of Chinese
Shuangjuan CHENG ; Haipo YANG ; Jiangxi XIAO ; Feiyu LI ; Hui XIONG ; Shuo WANG
Chinese Journal of Radiology 2015;49(4):310-312
Objective To investigate the MRI features of Fukuyama-type congenital muscular dystrophy(FCMD) in Chinese.Methods The MRI and clinical data of 3 patients with FCMD which had been diagnosed by gene analysis were retrospectively analyzed.Two females and one male were included in this study,and they underwent MR examination at 0.5,2.3,5.0 years old respectively.The main clinical manifestations were muscular hypotonia and severe developmental delay.Abnormalities on MR images were analyzed and recorded by two experienced radiologists.Results Unlayerdpoly microgyria involved in frontal lobes,numerous intraparenchymal cysts at the peripheral hemispheres and prolonged T1 and T2 signal in the white matter were found in all the 3 cases.Disorganized cerebellar folia,lissencephaly of cerebral cortices,flattened pons were detected in 2 cases.Cystic region of white matter incerebral cortices and enlarged fourth ventricle could be seen in one case.Conclusion There are typical MR imaging featuresof FCMD,and preliminary diagnosis can be made by the combination with clinical symptoms and biochemical analysis.
2. Clinical significance of epidermal growth factor receptor and thymidylate synthase expression in primary liver cancer
Feiyu GUO ; Jun YANG ; Shuming XIONG ; Maoqun ZHU ; Sen GAO ; Jianping LI
Chinese Journal of Hepatology 2018;26(9):666-669
Objective:
To investigate epidermal growth factor receptor (EGFR) and thymidylate synthase (TS) expression in primary liver cancer, and analyze its clinicopathological features and prognostic significance.
Methods:
Immunohistochemistry was performed using EnVision method to detect EGFR and TS expression in 41 cases of liver cancer. Correlation coefficient between EGFR and TS was calculated by Spearman method. Fisher's exact probability method or
3.Investigation and protection for endangered Coptis deltoidea.
Feiyu XIONG ; Yuntong MA ; Zhuyun YAN ; Xin CHEN ; Meng ZHU ; Run CHEN
China Journal of Chinese Materia Medica 2011;36(8):968-972
OBJECTIVETo investigate the history of the medicinal uses, resources, distribution, habitat and population characteristic of Coptis deltoidea, and provide basis for the protection and rational development and utilization of Radix Coptidis Deltoideae.
METHODThe relevant literature and data was scrutinized and herbarium was compared, interview and field survey methods were carried out.
RESULTThe medicinal history, resources, distribution, population characteristic and protective strategy of C. deltoidea were summarized. The sustainable development of C. deltoidea was discussed.
CONCLUSIONThe resource is endangered, the germplasm resources should be intentionally protected and ensure the sustainable development and utilization of C. deltoidea.
Conservation of Natural Resources ; methods ; Coptis ; growth & development ; Drugs, Chinese Herbal ; metabolism ; Ecosystem ; Endangered Species