1.Evaluation and management of soft tissue healing induced by closed fracture
Chinese Journal of Tissue Engineering Research 2007;0(11):-
The criterion of injury severity is an important part of evaluation,which can affect the treatment for closed fracture.The reaction in soft tissue healing process contains microvascular responses and inflammation.Take soft tissue with low immunity as a incision will lead to wound dehiscence and deep infection.Therefore,realization of injury severity lays a foundation for effective treating with closed fracture.Many treatment methods,such as splint fixation,cryotherapy,compression or delayed operation,can prevent soft tissue from a second injury,and promote self-repair ability prior to operation.The newly development surgical tech-nique can improve efficacy of therapy,meantime,decrease the incidence of complications.
2.Practice of taking patient's symptoms as the starting point in clinical teaching of obstetrics and gynecology
Chinese Journal of Medical Education Research 2013;(6):609-611
Objective To understand the effects of reform on clinical teaching taking patient's symptoms as the starting point and to investigate students' recognition degree towards this reform and their information feedback.Methods Totally 42 clinical students of the second clinical medical college (the second class) of China Three Gorges University were enrolled in the study and clinical teaching taking patient's symptoms as the starting point was conducted.Thirty-nine clinical students of the second clinical medical college (the fourth class) were enrolled as control group and traditional method was conducted.Effects of clinical teaching were evaluated by examination score and students' recognition degree towards this reform was investigated by self-made questionnaire and information feedback.Data were processed using SPSS 13.0 statistical software; t tests were used to compare students' scores of theoretical test and skill test; P < 0.05 signifies that the difference is statistically significant.Results There was no statistical difference in theoretical test score between experiment group and control group (P > 0.05).Skill test scores were higher in experiment group than in control group (P<0.01).Students highly admitted this teaching mode and they thought that this mode can improve their self-study ability,clinical practice skill and clinical thinking ability without influencing their theoretical learning.Conclusions Practice of clinical teaching taking patient's symptoms as the starting point is feasible,which can increase scores of skill test significantly without influencing scores of theoretical test.
3.Primary survey of dry eye in children
Ophthalmology in China 2006;0(06):-
Objective To prove the existence of dry eye in children and to learn the clinical characteristics of them. Design Prospective observational case series. Participants 38 cases(76 eyes) of suspected children of dry eye diagnosed by adult standard and 38 normal children subjects. Methods 38 suspected child patients were studied who were diagnosed clinically with dry eye by adult standard, and were followed up 6 months. The control group consisted of 38 normal children with no significant difference in age. Dry eye examinations including Schirmer test, break-up time(BUT) and fluorescein staining were performed on these two groups. Following items were recorded in 38 suspected children of dry eye, including symptoms and causations. Main Outcome Measures Symptoms, Schirmer test, BUT and fluorescein staining. Results In the 38 suspected patients, frequent blinking was the most common symptom in 21 cases(55.26%), followed by dryness (15 cases, 39.47%), redness (14 cases, 36.84%) and photosensitivity (14 cases, 36.84%). The Schirmer test and BUT were decreased remarkably in the suspected patients compared to those of normal subjects (P=0.0000). In both groups, right eyes were correlated with left eyes in both Schirmer test and BUT. Between these two groups, Schirmer test was nol correlated with BUT. In the suspected patients, the results of BUT and fluorescein staining were improved (P
4.Role of Warburg effect in arsenic carcinogenesis: a recent advance
Chinese Journal of Endemiology 2017;36(1):70-73
The glucose metabolism pathways including glycolysis and oxidative phosphorylation in vivo.The metabolism of tumor cells depends on glycolysis,which enhances the adaptability of tumor cells to the microenvironment and promotes the proliferation of tumor cells,which is called Warburg effect.Arsenic is one of the chemical pollutants,which is widely distributed in natural environment.International agency for research on cancer (IARC) has made it clear that arsenic and its compounds are carcinogens.However,the mechanism of carcinogenesis induced by arsenic still remains obscure.Recently,researchers have found that Warburg effect plays an important role in the process of arsenic carcinogenesis.In this paper,we have reviewed the definition and function of glycolysis,its relationship with inflammation and tumorigenesis,and the role of Warburg effect in arsenic carcinogenesis.
5.Screening on colonization of multidrug-resistant organisms in neonatal intensive care unit newborns on admission
Li-juan WANG ; Li-jun DU ; Fei-fei LUO
Chinese Journal of Infection Control 2014;(12):714-716
Objective To investigate colonization of multidrug-resistant organisms (MDROs)in neonatal intensive care unit (NICU)newborns on admission.Methods From April to November 2013,293 newborns who admitted to NICU of a hospital were screened for methicillin-resistant Staphylococcus aureus (MRSA)by nasal and throat swabs and for extended-spectrumβ-lactamases (ESBLs)bacteria and vancomycin-resistant Enterococcus (VRE)by anal swabs.Results Of 293 newborns,61 were detected MDROs (20.82%).The positive rate of MDROs screening in newborns aged <3 days(5.92%)was lower than those aged <3-6 days(37.74%)and 7-28 days (43.66%), the difference was significant (P =0.000).The major colonized MDROs were ESBLs-producing bacteria(83.60%), the major colonized site was anus(88.52%).Conclusion Neonatal anus and stool are important sources of MDROs in NICU;more attention should be paid to colonization screening for MDROs by anal swabs in newborns aged >3 days,and appropriate isolation measures should be taken for positive screening patients to prevent the transmission of MDROs.
8.Changes of local dentition with fixed implant prostheses.
Qiang LUO ; Lei ZHANG ; Qiu-fei XIE
Chinese Journal of Stomatology 2013;48(5):317-320
9.Percutaneous endoscopic gastrostomy (A report of 6 cases)
Dawei CHEN ; Zhewei FEI ; Mingde LUO
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Ojective To study the gastrostomy implemented by minimally invasive surgery for long enteral nutrition. Methods With the help of endoscopy the site of Puncture was selected between the lesser and greater curvature of the stomach. Under local anesthesia percutaneous gastrostomy was performed in 6 patients for long enteral nutrition. Results It took 10 to 15 minutes to finish the operation. No complication occurred during and after operation. Conclusions Percutaneous endoscopic gastrostomy may decrease the surgical invasion and shorten the operative time.
10.Clinical Research on External Application and Rectal Instillation with Chinese Medicine in Treatment of Chronic Renal Failure Combined with Acute Gouty Arthritis
Qun YI ; Yaping FEI ; Ziping LUO
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(6):1438-1441
This study was aimed to investigate the curative effect on external application and rectal instillation with Chinese medicine in the treatment of chronic renal failure (CRF) with acute gouty arthritis (GA). A total of 82 CRF patients with acute GA from the First People's Hospital of Hengyang City were randomly divided into the study group (n = 42), which was treated with external application and rectal instillation with Chinese medicine, and the control group (n = 40), which was treated with prednisone. The comparison was made on symptoms and body signs of GA, blood uric acid, creatinine, creatinine clearance, adverse reaction, and recurrence rate between two groups. The re-sults showed that there was no significant difference on alleviating of joint swelling and pain between the study group and the control group. Compared with pretreatment, the blood uric acid and creatinine were significantly decreased after treatment in the study group (P< 0.01). The creatinine clearance was obviously increased (P < 0.05). There were no significant differences on blood uric acid, creatinine and creatinine clearance in the control group before and after treatment. There was no adverse reaction in the study group. In the one-month follow-up, there were only three recurrent cases in the study group, which were obviously better than the control group (P< 0.01). It was concluded that external application and rectal instillation with Chinese medicine had a good curative effect on CRF with acute GA in the near future with low recurrence rate and no adverse reaction, which was worthy of popularizing in the clinical practice.