1.Characteristic of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia
Journal of Clinical Neurology 2017;30(4):278-280
Objective To compared the characteristics of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia (HHcy) and primary hypertension.Methods The level of homocysteine (Hcy) of 258 cerebral infarction patients with primary hypertension were detected, and patients were divided into H type hypertension group and hypertension group according to the level of Hcy.The cerebrovascular pathological changes were observed by DSA.Results There were 112 cases in H type hypertension group, and 146 cases in hypertension group.There had no significant difference between the two groups in gender, age, systolic pressure, diastolic pressure, and the rates of drinking and smoking (all P>0.05).Internal carotid artery (ICA) and middle cerebral artery (MCA) were involvements, and it was mainly with intracranial artery stenosis in the two groups.Compared with hypertension group, the rates of intracranial vessel lesion and severe cerebrovascular stenosis in H type hypertension group were significantly increased, and the rate of collateral vessels was significantly decreased(all P<0.05).Conclusion The stenosis of cerebrovascular seems much more narrower, heavier, and have less collateral circulation in cerebral infarction patients with H type hypertension.
2.Explore the Researching Thoughts of Senile Dementia
International Journal of Traditional Chinese Medicine 2009;31(1):19-
This article reviewed hot spot and problems in the research of the senile dementia,and proposal the researching thoughts and the tentative treament plan of this disease.
3.An Algorithm for Microcirculatory Blood Flow Velocity Measurement Based on Trace Orientation in Spatiotemporal Image.
Journal of Biomedical Engineering 2015;32(2):446-450
The velocity of blood in vessels is an important indicator that reflects the microcirculatory status. The core of the measurement technology, which is based on spatiotemporal (ST) image, is to map the cell motion trace to the two-dimensional ST image, and transfer the measurement of flow velocity to the detection of trace orientation in ST image. This paper proposes a trace orientation measurement algorithm is based on Randomized Hough Transformation and projection transformation, and it is able to estimate trace orientation and flow velocity in noisy ST images. Experiments showed that the agreement between the results by manual and by the proposed algorithm reached over 90%.
Algorithms
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Blood Flow Velocity
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Humans
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Microcirculation
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Spatio-Temporal Analysis
4.Clinical advancement of aromatase inhibitors in the therapy for human breast cancer
Fei FEI ; Jinsong LU ; Zhimin SHAO ;
China Oncology 1998;0(01):-
We review the proceedings on the methods of how the aromatase inhibitor maintains its function, the recently developed drugs and the progress in the field of endocrine therapy for human breast cancer
6.Clinical characteristics and salvage treatment for recurrent nasopharyngeal carcinoma.
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(3):261-264
Adult
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Aged
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Carcinoma
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Humans
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Middle Aged
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Nasopharyngeal Neoplasms
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diagnosis
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pathology
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therapy
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Neoplasm Recurrence, Local
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therapy
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Salvage Therapy
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Young Adult
7.A comparison study of laparoscopic versus open liver lobectomy (segmentectomy) for hepatocellular carcinoma
Bangyu LU ; Wenqi LU ; Fei HUANG
Chinese Journal of Minimally Invasive Surgery 2005;0(07):-
Objective To investigate short-term effects of laparoscopic liver lobectomy for the treatment of hepatocellular carcinoma. Methods A comparison was made between 17 cases of laparoscopic liver lobectomy (segmentectomy) (Laparoscopic Group) and 22 cases of open hepatectomy (Open Group) from January 2001 to June 2004. The operative time, blood loss, blood transfusion amount, liver functions and blood picture before and after the surgery, and complications between the two groups were compared respectively. Results The operative time was longer in the Laparoscopic Group (median, 300 min) than in the Open Group (median, 145 min) ( u =107.05, P =0.023). Both groups presented a similar appearance in the blood loss and the blood transfusion amount. Serum levels of bilirubin and ALT varied within narrower limits in the Laparoscopic Group than in the Open Group. No significant difference was seen in blood pictures before and after the surgery in both groups. No complications happened in the Laparoscopic Group, whereas 4 cases of complications were observed in the Open Group (1 case of incision infection, 1 case of hydrothorax, 1 case of subphrenic dropsy, and 1 case of postoperative bleeding). Conclusions Laparoscopic liver lobectomy (segmentectomy) for hepatocellular carcinoma is minimally invasive, safe and effective.
8.Effects of amylin on bone minernal density and structure parameters of bone tissue in glucocorticoid-induced osteoporosis rats
Bangchao LU ; Jian WANG ; Fei QIAO ;
Journal of Medical Postgraduates 2003;0(05):-
Objectives:To investigate the effects of amylin on bone minernal density and structure parameters of bone tissue in glucocorticoid induced osteoporosis rats. Methods:Four groups of female Wistar rats (3 months old) were treated for 12 weeks as follows: ⅠNormal Control, ⅡDXM, Ⅲ DXM+AMY;Ⅳ DXM+Vitamin Da 3. By intramuscular injection of dexamethasone(XM)1mg/kg twice a week during the first 8 weeks, the animal model of Glucocorticoid induced osteopoprosis was established. After 12 weeks, BMD of the lumbar vertebrae and the femural bone were measured by DEXA. The bone morphology of the lumbar vertebrae was also determined. Results:①After the treatment with AMY, bone mineral density (BMD) was significantly increased at the lumbar spine and the femural bone. ( vs. DXM group, P
9.Therapeutic strategies and relevant clinical problems in non-small cell lung cancer with brain metastases
Chinese Journal of Clinical Oncology 2015;42(19):947-952
Brain metastasis is among the most common complications of non-small celllung cancer (NSCLC) and may obviously influence the survival and quality of life in the NSCLC patients. Recently, the development in traditional treatments, the widely-used micro-molecular targeted drugs, and the combined treatment have improved the overall survival and the quality of life of these patients. In addition, the exploration of new therapeutic targets and cognitive function protective methods for current treatments also deserves at-tention. This review emphasizes the relevant clinical and basic problems and the therapeutic strategies in NSCLC with brain metastases.
10.Clinical analysis for 48 cases of diffuse axonal injury
Yongsheng ZHOU ; Guanmin HUANG ; Fei LU
Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1197-1198
Objective To discuss the clinical feature, diagnostic main points and treatment of diffuse axonal injury(DAI). Methods The clinical materials and imaging findings and treatment and prognosis of 48 cases with DM were analyzed retrospectively. Results 18 cases showed a good outcome, while 12 were moderately disabled, 10 severely disabled or survived in a permanent vegetative state and 8 cases died. Conclusion To preserve the fluent respiratory tract, to control intracranial pressure, to treat with hyperbaric oxygenation and high-dose naloxone in early time were crucial in clinical practice to DAI.