1.Traumatic shock and systemic inflammation
Shimin CHEN ; Fei GE ;
Chinese Journal of Pathophysiology 1986;0(04):-
TraumaistheNo .1causeofdeathinpersonsundertheageof 4 5andtheNo .3causeof alldeaths .Manytraumapatientsdieofmultipleorganfailure(MOF) ,inducedbysystemicinflammatoryre sponsesyndrome(SIRS) .Thispaperreviewstherelationsoftraumaticshockwithsystemicinflammation . [
2.The requirements to clinicopathology about targeted therapy for breast cancer.
Chinese Journal of Pathology 2007;36(7):435-437
Antibodies, Monoclonal
;
therapeutic use
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Antibodies, Monoclonal, Humanized
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Antineoplastic Agents
;
therapeutic use
;
Antineoplastic Combined Chemotherapy Protocols
;
therapeutic use
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Breast Neoplasms
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drug therapy
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metabolism
;
pathology
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Carcinoma, Ductal, Breast
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drug therapy
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metabolism
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pathology
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Female
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Humans
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Receptor, ErbB-2
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metabolism
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Trastuzumab
3.Application of biodegradable materials in the clinical treatment and care of gynecology and obstetrics
Ling HUANG ; Fei GE ; Yan WU
Chinese Journal of Tissue Engineering Research 2014;(47):7672-7676
BACKGROUND:Recently, the biodegradable materials with good biocompatibility and with no adverse reaction have been widely applied in the clinical treatment and care of gynecology and obstetrics. The development of the biodegradable material is very rapid. OBJECTIVE:To summarize the application of biodegradable materials in gynecology and obstetrics. METHODS: The first author searched PubMed and CNKI databases for articles related to biodegradable materials in gynecology and obstetrics using the keywords of “degraded materials, biodegradable materials, gynecological care, surgery” in Chinese and English respectively. This article has an outlook of the potential application in gynecology and obstetrics based on clinical experience. RESULTS AND CONCLUSION:Biodegradable materials with good biocompatibility and biological security play an important role in biomedical materials. Their polymers and degradation products show smal adverse reactions to the body, and have good biomechanical properties, physical and chemical properties and good workability, which have been widely used in gynecology and obstetrics, such as absorbable stylolite and tampon tape. Although we have made a great progress on the biomaterial research, it stil has the limitation and safety flaws in the clinic. As the biomaterial research is further developed, the biomaterial application prospect wil be more promising.
4.Effects of triptolide on endothelin-1 and its gene expression in lung of asthmatic guinea-pigs
Qing HAN ; Chuansheng GE ; Li FEI
Chinese Pharmacological Bulletin 1986;0(06):-
AIM To explore the effects of trip-tolide on endothelin-1 and its gene expression in lung of asthmatic guinea-pigs. METHODS The contents of ET-1 in lung of asthmatic guinea-pigs were measured with radioimmunoassay, and the expressions of ET-1, ETA, ETB and ECEmRNA with reverse transcription DNA polymerase chain reaction (RT-PCR). RESULTS 0 All of the indexes were increased after guinea-pigs were induced asthma. At the 4th hour after first induction of asthma, ET-1 reached the top, but at the 2rd hour, ET-1mRNA, ETAmRNA and ECEmRNA were markedly higher than control group (P
5.Generation mechanisms and management strategies of adverse reactions to Bevacizumab during cancer treatment.
Chinese Journal of Oncology 2010;32(7):481-486
Angiogenesis Inhibitors
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adverse effects
;
therapeutic use
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Angiotensin-Converting Enzyme Inhibitors
;
therapeutic use
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Antibodies, Monoclonal
;
adverse effects
;
therapeutic use
;
Antibodies, Monoclonal, Humanized
;
Aspirin
;
administration & dosage
;
therapeutic use
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Bevacizumab
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Hemorrhage
;
chemically induced
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Humans
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Hypertension
;
chemically induced
;
drug therapy
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Intestinal Perforation
;
chemically induced
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surgery
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Neoplasms
;
drug therapy
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Proteinuria
;
chemically induced
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Thromboembolism
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chemically induced
;
drug therapy
6.Prokaryotic Expression of the Partial gB Gene of the Marek’s Disease Virus
Ya-Feng QIU ; Fei-Fei GE ; Pu-Yan CHEN ;
China Biotechnology 2006;0(02):-
The partial segment of Marek′s disease virus (MDV) glycoprotein B (gB) gene was amplified by PCR. The segment was cloned into pET-28a vector to obtain the recombinant pET-gB plasmid. The recombinant plasmid was transformed into E.coli BL21,and expressed in very high level as inclusion body after induced with 1.0mmol/L IPTG. The inclusion body was solubilized in urea (8mol/L) . The purified protein was obtained by use of His?Bind affinity chromatography. Mice were immunized i.p. by the purified protein to make the polyclonal antibody. The titer of the antibody by indirect ELISA was 1?10~ -5 . Moreover, the analysis by western blot proved that antibody was specific to the recombinant protein. These works lay a favorable foundation for the study of the immune response by MDV gB.
7.A research of treating infertile PCOS women with oocyte in vitro maturation
Fei GONG ; Shuoping ZHANG ; Ge LIN ; Guangxiu LU
Journal of Chinese Physician 2008;10(9):1193-1195
Objective To develop a method for treating infertile women with polycystic ovary syndrome(PCOS)by ooeyte in vitro maturation(IVM).Methods On day 3~4 of menstrual cycle,infertile women with PCOS were administrated with(100~150IU)FSH/day for 3 days.On day 8~10,when the follicle diameter reached 10~14mm and endometrium>5mm,the immature oocytes weFe picked up and cultured in vitro for 28~31 hours.Then,ICSI and embryo transfer were performed.Results 3 clinic pregnancies were established among 12 infertile women.the pregnancy rate was 25.0%.Conclusion This research indicates that IVM is a feasible technology for the infertile women with PCOS.
8.Carotid Atherosclerotic Plaque and Ischemic Cerebrovascular Diseases
Shizao FEI ; Yidong GE ; Guanbao CHEN ; Hongbo PANG
International Journal of Cerebrovascular Diseases 2008;16(3):210-213
This article summarizes the components,the formation and development of carotid atherosclerotic plaque,the factors affecting the stability of plaque,the mechanisms of plaquecaused ischemic cerebrovascular disease as well as the diagnosis of plaques and the treatmentstatus.
9.A study on the facial morphometry of the attractive Uygur females in Xinjiang
Fei GE ; Jinyu WANG ; Hongyan DENG ; Shugang LI ; Li ZHAO
Journal of Practical Stomatology 1995;0(04):-
Objective:To obtain the normal values of the facial soft tissue measurements of the attractive Uygur females in Xinjiang by photogrammetric analysis,and to study the relationship between the facial feature of attractive Uygur females and the neoclassical canons. Methods:31 attractive Uygur women were selected, standardized and referenced frontal photographs of faces were taken,and 14 standard anthropometric marks were determined,then measurements were performed by photoshopCS software.Results:Intercanthal width was rather smaller than nose width and larger than eye fissure width;nose width occupied more than 1/4 of face width or 2/3 of mouth width.The chin occupied 2/3 of the entire mandibular height.There was positive correlation among many horizontal and vertical facial soft tissue measurements.Conclusion:The facial features of the attractive Uygur females in Xinjiang fit the classical facial canons to some extent. There is pertinence in attractive facial form and features.
10.Multiple Factors on Bone Graft Healing of Mandible Reconstruction
Ge YANG ; Min HU ; Chunming LIU ; Fei GAO ; Rongfa BU
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To study multiple factors on bone graft healing of mandibular reconstruction. METHODS Patients were divided into two groups: healing group(31 cases) and healing delayed group(10 cases).By comparison between two groups,the factors on wound healing after bone grafting were studied. RESULTS In patient′s age and sex,bone graft type and size,and history of operation on bone graft done,there were no differences between two groups.Extraoral and intraoral passage was the important factor to two groups,P=0.000. CONCLUSIONS It is important for us to treat wound carefully while bone graft is carried with extraoral and intraoral passage.