【Objective】 To evaluate the clinical efficacy of 200 W blue laser vaporization of prostate and the possibility of developing such surgery into day surgery. 【Methods】 The clinical data of 30 patients treated during Aug. and Sep.2022 were retrospectively reviewed. The residual urine volume, urine flow rate, International Prostate Symptom Score (IPSS) and Quality of Life Scale(QoL) score before and after surgery were compared. The operation time and postoperative routine urinary red blood cell count were recorded. 【Results】 All surgeries were successful and the catheter was moved 1 day after surgery. The operation time was (12.2±5.1) min, postoperative bladder irrigation time (20.0±4.2) h, and urinary red blood cell count (806.2±16.3)/μL. Recatheter was needed in 1 patient. The urinary flow rate before surgery, immediately and 1-month after surgery were (10.6±3.5) mL/s, (24.2±5.6) mL/s, and (27.2±3.1) mL/s, respectively. The residual urine was (57.3±3.2) mL before surgery and (5.6±3.1) mL 1-month after surgery. The average preoperative IPSS and QoL scores were (25.1±1.6) and (5.4±0.7), and were (9.5±1.4) and (2.9±0.6), respectively, 3-months after surgery. 【Conclusion】 Transurethral 200 W blue laser vaporization of the prostate is a practical and feasible surgical technique for the treatment of benign prostatic hyperplasia. It is effective, rapid and safe, and can greatly shorten the length of hospital stay and improve perioperative safety. With the improvement of clinical application technology, it can be a choice of prostatic day surgery.

【Objective】 To observe the efficacy of blue laser side light in the vaporization and enucleation of non-muscle invasive bladder cancer (NMIBC). 【Methods】 A retrospective analysis was performed on the data of NMIBC patients who received transurethral enucleation of bladder tumor (TURBT) using a 50 W blue laser treatment device. The efficacy and safety of surgery were evaluated by observing the application of blue laser in the treatment of bladder cancer in different locations, operation time, presence of bladder perforation and postoperative urine routine indicators. 【Results】 A total of 16 patients completed the surgery, including 5 cases with multiple bladder tumors, 9 with single bladder tumor, and 2 with lichenoid lesions. The postoperative pathological results showed all of them were NMIBC. The operation time was (10.4±4.7) min, postoperative urinalysis was (689.4±316.7)/μL, and no intraoperative bladder perforation occurred. 【Conclusion】 The lateral infusion mode of 50 W blue laser therapy device can be applied to the surgical treatment of NMIBC. The basal vaporization and enucleation of bladder cancer can be performed under direct vision conditions, and the multi-angle enucleation is suitable for bladder cancer in different positions. The tissue penetration depth of blue laser is shallow, which is conducive to the diagnosis and grading of pathological tissues.

【Objective】 To explore the efficacy and safety of "ditching and ridge removal" with 450 nm semiconductor blue laser in the treatment of large volume benign prostatic hyperplasia (BPH), in order to promote the clinical application of this method. 【Methods】 A retrospective study was conducted on 30 patients with large volume BPH treated with "ditching and ridge removal" with 450 nm semiconductor blue laser in Yingsheng Branch of Tai’an Central Hospital during Sep.and Dec.2023.The laser operation time, level of hemoglobin before and after operation, bladder irrigation time after operation, urinary catheter indwelling time, postoperative hospital stay, and intraoperative and postoperative complications were recorded.The changes of international prostate symptom score (IPSS), quality of life scale (QoL) score, maximum urinary flow rate (Qmax) and post-void residual volume (PVR) were compared before and 1 month after operation. 【Results】 The volume of prostate was (104.5±14.52) mL, the laser operation time was (20.13±2.98) min, and the bladder irrigation time was (20.27±2.56) h.The catheter was removed in all patients 2 days after operation, and all patients were discharged 3 days after operation.One month after operation, the IPSS, QoL, Qmax and PVR were significantly improved as compared with those before operation (P<0.05).No complications occurred during the follow-up. 【Conclusion】 "Ditching and ridge removal" with 450 nm semiconductor blue laser is a new, safe and effective method in the treatment of large volume BPH.

【Objective】 To compare the clinical efficacy and safety of transurethral blue laser vaporization of prostate and transurethral resection of prostate (TURP) in the treatment of benign prostatic hyperplasia (BPH). 【Methods】 The clinical data of 142 BPH patients undergoing surgery in our hospital during Jan.and Aug.2023 were retrospectively analyzed.The patients were divided into blue laser group (n=72) and TURP group (n=70).The operation time, hemoglobin (Hb) decrease, bladder irrigation time, catheter indwelling time and postoperative hospital stay were compared between the two groups.The changes of international prostate symptom score (IPSS), quality of life score (QoL), maximum urinary flow rate (Qmax), postvoid residual volume (PVR), international index of erectile function-5 (IIEF-5) score and complications before and 6 months after operation were also compared. 【Results】 Six months after operation, the IPSS, QoL, Qmax and PVR were significantly improved in both groups (P<0.05), but there were no significant differences between the two groups (P>0.05). Compared with the TURP group, the blue laser group had shorter operation time \[(47.04±4.03) min vs.(25.46±5.84) min\], shorter postoperative bladder irrigation time \[ (54.17±4.99) h vs.(21.18±4.11) h\], shorter catheter indwelling time \[5(5, 6) d vs.2(2, 2) d\], shorter postoperative hospital stay \[7(7, 8) d vs. 4(3, 4) d\], less Hb decrease \[(9.61±2.16) g/L vs.(4.31±2.34) g/L\], and lower incidence of complications (51.4% vs.4.2%), with significant differences (P<0.05).Six months after surgery, the blue laser group had higher IIEF-5 score than that the TURP group \[(20.06±2.13) vs. (18.93±1.85)\], with significant difference (P<0.05). 【Conclusion】 Both transurethral blue laser vaporization of prostate and TURP can effectively treat BPH, but the former is more effective, for it has advantages of short recovery time, few complications and small impact on the sexual function of patients.

【Objective】 To explore the effects of sexual function-preserving 450 nm blue laser vaporization of the prostate on the postoperative sexual function of patients with benign prostatic hyperplasia (BPH), and to evaluate the clinical efficacy, safety and feasibility of this procedure. 【Methods】 The clinical data of 20 BPH patients treated in our department during Jan. and Mar.2023 were analyzed. The International Prostate Symptom Score (IPSS), Quality of Life Scale (QoL) score, maximum urinary flow rate (Qmax), residual urine volume (PVR) and International Index of Erectile Function (IIEF-5) data were compared before and after the operation. The operation time, postoperative catheter indwelling time, and hospital stay were recorded. The ejaculation status 2 months after operation was followed up. 【Results】 All 20 patients completed the operation successfully. The operation time was (13.41±4.30) min, catheter indwelling time (1.2±0.4) d, and hospital stay (3.0±0.6) d. The IPSS, QoL, PVR and Qmax data 1 month after operation were significantly improved compared with those before operation (P<0.01). Two months after operation, all patients had sex and ejaculated, and no retrograde ejaculation occurred. The erection function remained unchanged (P>0.05). 【Conclusion】 The modified 450 nm blue laser vaporization of the prostate can improve the urination symptoms of BPH patients while retaining sexual function. It is a safe and feasible technique for BPH patients who have sexual needs, and provides an alternative surgical approach for those looking to preserve sexual function.

【Objective】 To investigate the efficacy and safety of 450 nm blue laser with 6 o’clock positioning in the treatment of middle lobe hyperplasia of prostate, in order to promote the clinical application of this surgery. 【Methods】 Clinical data of 20 patients with middle lobe hyperplasia of prostate treated with 450 nm blue laser with 6 o’clock positioning during Mar.and Aug.2023 were retrospectively analyzed.The operation time, postoperative bladder irrigation time, catheter indwelling time, hospital stay, and complications were recorded.The maximum urinary flow rate (Qmax), post-void residual volume (PVR), quality of life scale (QoL), international prostate symptom score (IPSS) before surgery and 1 month after surgery were compared. 【Results】 The operation time was (26.80±7.22) min, and bladder irrigation time was (20.50±1.79) h.The catheter was removed on the next day after surgery and all patients were discharged 2 days after operation.Compared to preoperative, one month after surgery, the Qmax [(7.40±1.05) mL/s vs.(19.60±1.76) mL/s] was significantly higher, PVR [(73.50±12.26) mL vs.(9.25±4.94) mL], QoL [(4.55±1.19) vs.(1.95±0.95)], and IPSS [(26.55±1.88) vs.(10.05±1.36)] were significantly lower, the differences being statistically significant (P<0.05).No complications occurred during operation and 1-month follow-up. 【Conclusion】 The 450 nm blue laser with 6 o’clock positioning is a new, safe and effective surgical treatment of middle lobe hyperplasia of prostate, which is worthy of clinical promotion and application.