Objective To explore the value of MRI features of the appendixes bone in differentiating vertebral myeloma from metastatic tumor. Methods There were vertebral myelomas and metastatic tumors in 32 cases respectively involved the appendixes bones,the number,positions,forms,size,distribution ranger and T_1 of the lesions,the vertebral pedicles and the diameters of the cross sections of vertebrallaminas were analysed.Results Among the 32 cases of vertebral myeloma,the destruction of appendixe was bilateral in 21 cases andunilateral in 11 cases.Totally 89 lesions were checked out ,of them,the lesions were the form of mass or nodule in 39,patch in 28,mixed form in 12.In compared with its adjacent and normal one,the ratio of evary invaded vertebral pedide , vertebral lamina and spinous process was between 1.048~2.135 . There was significant difference (P0.05).Conclusion The difference of MRI features of the appendixes bone invaded by vertebral myeloma and by metastatic tumor is helpful in distinguishing vertebral myeloma from metastatic tumor.

Objective:To evaluate in vitro antifungal activities of zhexinmycin against dermatophytes. Methods: The minimum in-hibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of zhexinmycin against 7 strains of dermatophytes were determined by using broth microdilution method according to CLSI M-38A. Results:The MIC of zhexinmycin against dermatophytes was within the range of 0. 125-2. 000μg·ml-1 . The MFC was within the range of 0. 250-4. 000μg·ml-1 . Conclusion:Zhexinmycin shows strong in vitro antifungal effect on multiple fungi such as Epidermophyton floccosum, Trichophyton rubrum, Trichophyton violaceum, Mi-crosporum canis, Trichophyton mentagrophytes, Trichophyton tonsurans and Microsporum gypseum.

Objective To observe the bacteriostatic effect of chitosan lactate with different relative molecular masses in vitro. Methods The MICs of the chitosans lactate with different relative molecular masses against the usual pathogens were detected,and the MBCS against two standard strains were also determined. Levofloxacin hydrochloride was used as a control drug. Results The MIC90 of chitosan lactate with 10,30,50kDa against 50 strains of gram-positive cocci and 50 strains of gram-negative bacilli were 0.5,1~4,0.5~4mg?mL-1 and 1~4,0.5~1 ,0.5~4mg?mL-1,respectively. The MIC90 of levofloxacin hydrochloride against the 50 strains of gram-positive cocci and 50 strains of gram-negative bacilli were 4～8 and 8～16?g?mL-1,respectively. ATCC 25923 strain of S.aureus and ATCC 25922 strain of E.coli could be killed by 10kDa chitosan lactate in the concentration of 4mg?mL-1. The MBCS of levofloxacin hydrochloride against ATCC25923 strain of S.aureus and ATCC 25922 strain of E.coli were 2 and 4?g?mL-1,respectively. Conclusion The 4 species of the experimental bacteria could be inhibited by the chitosan lactate with 10,30 and 50kDa Mr in vitro,but the inhibitory effect of the chitosan lactate with 10kDa Mr was stronger among them. ATCC 25923 strain of S.aureus and ATCC25923 strain of E.coli could be killed only by 10kDa chitosan lactate in vitro,not by others.

Objective To investigate the diagnostic value of one-stop liver magnetic resonance dynamic enhanced MRA for esophageal and gastric varces.Methods 82 patients with liver cirrhosis portal hypertension who were diagnosed by clinical and laboratory detect were taken,conducting liver horizontal scanning and multitemporal three dimensional dynamic enhanced scanning using Philips Achieva 1.5T MRI scanner,and then make maximum intensity projection(MIP) at work station to draw up portal vein image,observing the form and distribution of portal vein and its branches,meanwhile refer to cross sectional image to carefully observe whether there was cirsoid vein in esophagus and stomach,and further the source,degree and depth of cirsoid vein were compared,and whether there was cirsoid vein in other parts,and the pathological situation of liver.Compared with the result of gastroscope inspection,whether there is cirsoid vein in esophagus and stomach.Results The trunk and class-Ⅲ branches of portal vein of all patients had been clearly shown.In this team,there were esophageal and gastric varces in 78 patients,specifically including varices of fundus of stomach & esophageal varices in 27 patients,and varices of fundus of stomach and varices of body of stomach in 19 patients.Meanwhile,it diagnose 6 patients with liver cirrhosis and liver cancer and indicate 8 patients with liver cirrhosis nodule cancerization.The endoscope found out esophageal varices and varices of fundus of stomach in 68 patients,specifically including gastric varicesa and esophageal varices in 25 patients,sole gastric varicesa in 8 patients,and sole esophageal varices in 35 patients.Conclusion The one-stop liver three dimensional dynamic enhanced MRA is with great value in diagnosing the location and degree of esophageal varices and varices of fundus of stomach of patients with portal hypertension.The overall effect is better than endoscope.

0.05),however,it can shorten curative time obviously on Ⅱ type dental ulcer.Simultaneously,the general reaction and focal mucosa of borneolum and borax pellicle group had no obvious variation before and after the test.Conclusions Chitosan has no effect on min-pigs' nerve,cardiovascular and respiratory system;and it is relatively safe given by mouth or peritoneal injection.The borneolum and borax pellicle can shorten curative time obviously on Ⅱtype dental ulcer.

Objective To explore the cross-sectional study of depressive and emotional regulation strategies of elderly residents in Yinchuan and their relationship.Methods A total number of 1 043 elderly cases,including 505 from 5 nursing institutions and 538 from 5 communities in Yinchuan city were chosen,from March to May,2016.Depression survey using the Geriatric Depression Scale (GDS),emotional adjustment strategies were conducted using the Gross Emotional Regulatory Questionnaire and the Rumination Scale.Results The overall incidence rate of depression among the elderly residents appeared as 32.0％,with 35.5％ in the communities and 28.3％ in the nursing homes and the difference was statistically significant (x2=6.187,P＜0.05).There was no significant difference in the incidence of depression among the elderly and the aged in the community (x2=0.066,P=0.798) by the trend analysis method.The score of GDS for the 1 043 elderly was (9.1 ±5.7) points.The scores on cognitive reappraisal in emotional adjustment strategies and on expression inhibition were (26.7 ± 8.0) and (16.3 ± 6.6) points respectively.The score of the rumination was (34.5 ± 11.7) points.There were significant differences in cognitive reappraisal scores on different sex,hobbies and physical exercise (all Ps＜0.05) among the elderly.There were significant differences in rumination scores among the elderly with different age,marital status,cultural level,interest (all Ps ＜0.05) and in the scores of expression inhibition among the elderly with different levels of education and income (all Ps＜0.05).There appeared a negative correlation between the depression scores and cognitive reappraisal (r=-0.400,P＜0.01) but a positive correlation between the scores of depression and rumination (r=0.652,P＜0.01).Conclusion The incidence of depression identified in the elderly residents appeared high and was associated with emotional adjustment strategies,in Yinchuan city.

Dental caries are common diseases in children and often affect their growth and development. In order to understand the dental caries status of preschool children in Qingdao, a total of 1 690 children aged 3-6 years were screened from 13 kindergartens in two districts of Qingdao. The oral health examination was conducted according to the WHO standard, including the decayed?missing?filled index and pigmentation status. The prevalence of caries, the mean decayed,missing and filled tooth (dmft) and the mean dmfs were calculated. The results showed that the prevalence of deciduous teeth caries of children was 65.3% (n=1 103) with the mean dmft and dmfs about 3.2 and 5.4. There was a statistically significant difference in the prevalence of deciduous teeth caries among different age groups (P<0.001). There was a statistically significant difference between the prevalence of deciduous teeth caries with and without pigmentation (P<0.001). The prevalence of caries in preschool children in Qingdao is high and more attention should be paid to their dental caries.

Objective:To observe the effects of hyperthermia on the sensitivity of gastric cancer cell lines to paclitaxel (TAX) . Methods :To establish TAX-resistant gastric cancer cell line through a method of increasing concertration gradient and named it MKN-45/TAX .Immunocytohistochemistry staining method was used to detect the expression of multi-drug resistance gene (MDR1) in MKN-45/TAX and MKN-45 .CCK-8 test was used to detect the proliferation inhibition rates in two kinds of cell lines under different temperatures and different TAX concentration .Real-time polymerase chain reaction (RT-PCR) and West-ern blotting were used to detect the expression of MDR1 mRNA and P-glycoprotein (P-gp) before and after target siRNA treat-ment .Results:Establishment of MKN-45/TAX cell line was successful .The expression level of MDR1 was high in MKN-45/TAX whereas it was low in MKN-45 .As TAX concentration increased ,the proliferation inhibition rates of both cell lines in-creased .At 42 ℃ the proliferation inhibition rate of MKN-45/TAX to TAX chemotherapy decreased ,while that of MKN-45 was the opposite .Both the expression of MDR1 mRNA and P-gp decreased after the siRNA transfection .Conclusions :Hyper-thermia combined with chemotherapy may enhance the resistance of TAX-resistant gastric cancer cell line to TAX ,while it may enhance the sensitivity of TAX-sensitive gastric cancer cell line to TAX .The mechanism may be related to the expression of MDR1 .

Dental caries are common diseases in children and often affect their growth and development. In order to understand the dental caries status of preschool children in Qingdao, a total of 1 690 children aged 3-6 years were screened from 13 kindergartens in two districts of Qingdao. The oral health examination was conducted according to the WHO standard, including the decayed?missing?filled index and pigmentation status. The prevalence of caries, the mean decayed,missing and filled tooth (dmft) and the mean dmfs were calculated. The results showed that the prevalence of deciduous teeth caries of children was 65.3% (n=1 103) with the mean dmft and dmfs about 3.2 and 5.4. There was a statistically significant difference in the prevalence of deciduous teeth caries among different age groups (P<0.001). There was a statistically significant difference between the prevalence of deciduous teeth caries with and without pigmentation (P<0.001). The prevalence of caries in preschool children in Qingdao is high and more attention should be paid to their dental caries.

Dental caries are common diseases in children and often affect their growth and development. In order to understand the dental caries status of preschool children in Qingdao, a total of 1 690 children aged 3-6 years were screened from 13 kindergartens in two districts of Qingdao. The oral health examination was conducted according to the WHO standard, including the decayed-missing-filled index and pigmentation status. The prevalence of caries, the mean decayed, missing and filled tooth (dmft) and the mean dmfs were calculated. The results showed that the prevalence of deciduous teeth caries of children was 65.3% (n=1 103) with the mean dmft and dmfs about 3.2 and 5.4. There was a statistically significant difference in the prevalence of deciduous teeth caries among different age groups (P<0.001). There was a statistically significant difference between the prevalence of deciduous teeth caries with and without pigmentation (P<0.001). The prevalence of caries in preschool children in Qingdao is high and more attention should be paid to their dental caries.