1.Comparison of Ultrasonic Method and Continuous Reflux Extraction Process of Total Flavonoids from Radix Astragali
Fansheng KONG ; Yongguang BI ; Aiqun SUN ; Chunyan YAN
China Pharmacy 2005;0(19):-
OBJECTIVE:To compare the ultrasound method and continuous reflux extraction process of total flavonoids from Radix Astragali.METHODS:The extraction technology was optimized by orthogonal test with the content of total flavonoids of Radix Astragali as index and with the concentration of ethanol,extraction time,solid-fluid ratio,extraction temperature as factors.RESULTS:Ultrasound extraction process was superior to continuous reflux extraction process.Optimal extraction technology was as follows:the concentration of ethanol of 75%,ultrasonic extraction time of 20 min,solid-liquid ratio of 1:10,ultrasonic extraction temperature of 25 ℃ and extraction rate of 0.325%.CONCLUSION:As compared with continuous reflux extraction process,ultrasonic extraction is fast to operate,solvent saving and high extraction.
3.Mathematical kinetic model of dual-frequency ultrasound assisted extraction of effective components traditional Chinese medicine.
Yongguang BI ; Taiqiu QIU ; Kang LI ; Kunping LI ; Fansheng KONG
China Journal of Chinese Materia Medica 2010;35(2):154-157
OBJECTIVETo establish the mathematical kinetic model of the components extracted from the Salvia miltiorrhiza.
METHODIn the conditions of ultrasound extracting the course of traditional Chinese medicine, the role of ultrasound intensity is large enough, the proliferation of boundary layer can be infinitesimal, as well as the solute upon the surface of medicine quickly into the main solution, we can assume that the whole process of extraction from the control of proliferation. A mathematical model of dual-frequency ultrasound extraction kinetics based on Fick's second diffusion law was established for traditional Chinese medicine. Based on material size and solid/liquid ratio significant factors.
RESULTWe adopt Origin software to carry out a mathematics simulation, the result showed: simulation graphics and experiment value are very fitting.
CONCLUSIONThis proves that S. miltiorrhiza extraction course accords with ordinary extraction dynamics equation at the dual-frequency ultrasound.
Drugs, Chinese Herbal ; chemistry ; Kinetics ; Models, Theoretical ; Particle Size ; Plants, Medicinal ; chemistry ; Salvia miltiorrhiza ; chemistry ; Ultrasonics
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