Objective To explore the postoperative observation and nursing points of traumatic glaucoma patients with Ex-PRESS glaucoma filtration device implantation .Methods The clinical data of 19 patients ( 19 eyes ) with traumatic glaucoma were retrospectively analyzed , and all patients received the Ex-PRESS glaucoma filtration device implantation under the scleral flap .The visual acuity , anterior chamber depth and hyphema , intraocular pressure and filtering bleb after the operation were observed , and the standardized postoperative nursing was carried out and summarized .Results The cases of visual acuity with the increase of 2 to 3 lines, the unchanged including the increase or decrease of 1 line and the decrease of 2 to 3 lines were respectively 9 (47.4%), 9 (47.4%) and 1 (5.3%) case 3 months after the operation.The cases of shallow anterior chamber were 2 cases (10.5%) one day after the operation, and the anterior chamber depth returned to normal on the second day after the operation through one to four mydriasis .The cases of intraocular pressure with 5 to 16 mmHg were 19 cases on the first week after the operation .The cases of intraocular pressure with 36 mmHg accompanied by filtering bleb were one case , and the cases of intraocular pressure with 9 to 17 mmHg were 18 cases 3 months after the operation .The cases of filtering bleb includingⅠ,Ⅱand Ⅳ were respectively 3, 15, 1 case 3 months after the operation, and the cases of functional filtering bleb includingⅠandⅡwere 18 cases (94.7%).Conclusions Ex-PRESS glaucoma filtration device implantation can improve the postoperative vision , and control the postoperative intraocular pressure in patients with traumatic glaucoma .The standardized postoperative nursing can reduce the postoperative complication , and increase the surgical effects .

AIM: With building a proliferation model of PA-induced VSMC, the effect of ATGL, a key fat metabolism enzyme, on the phenotype transformation of VSMC was preliminarily explored. METHODS: 40 μmol/L Atglistatin was added to the proliferation model of VSMC induced by PA (50 μmol/L, 100 μmol/L, and 200 μmol/L, respectively) at separately administered concentrations, and cell viability and cell proliferation were detected by CCK-8 and EDU; cell migration ability was detected by scratch assay; oil red staining was used to detect the accumulation of lipid droplets in VSMC was detected by oil red staining; the effects of PA on ATGL as well as the effects of smooth muscle contraction phenotype proteins were examined by Western blot. RESULTS: PA at a concentration of 100 μmol/L could significantly induce VSMC proliferation, promote lipophagy and increase lipid droplet accumulation in VSMC; meanwhile, Atglistatin could exacerbate these changes caused by PA and increase lipid droplet accumulation in VSMC. CONCLUSION: Atglistatin exacerbates PA-induced VSMC proliferation and increases VSMC lipid droplet accumulation, and exacerbates transformation of proliferative phenotype of VSMC.

When nanoparticles were introduced into the biological media, the protein corona would be formed, which endowed the nanoparticles with new bio-identities. Thus, controlling protein corona formation is critical to