1.Clinic observation on the Treatment of Benign Prostatic Hyperplasia with JueDuYin
Fanghong CAO ; Jin CAO ; Bing HU
International Journal of Traditional Chinese Medicine 2009;31(6):532-533
Objective To study the efficacy of JueDuYin in the treatment of benign prostatic hyperplasia (BPH). Methods 120 cases were randomly recruited into a treatment group and a control group, with 60 cases in each group.The treatment group was given JueDuYin, one dosage per day, while the control group was administrated with Finasteride, 5mg per day. After three courses of twelve weeks' treatment, the indications of international prostate symptom score (IPSS), residue urine (RU), Qmax and total prostatic value (IPV) were observed. Results There was significant changes in the valve of IPSS,RU, Qmax for both groups after the treatment compared (P<0.05~0.01). The therapeutic effects of the treatment group was obvious better than the control group (P<0.05).
2.INFLUENCE OF EXPERIMENTAL ATHEROSCLEROSIS ON SERUM COPPER, ZINC, CHROMIUM, MANGANESE, AND SELENIUM
Shantong ZHANG ; Kewei CUI ; Shouwei CAO ; Jingcun LI ; Fanghong LU ; Jianmei WU ; Licun WU ; Jie ZHANG ; Xiaochun YANG ; Jianhua ZHANG
Acta Nutrimenta Sinica 1956;0(04):-
0.05) but a statistically significant negative correlation was noted between serum cholesterol and zinc (r= -0.9986, P
3.Whole brain dynamic volume CT angiography and CT perfusion imaging in middle cerebral artery occlusion animal models
Juan YE ; Zhifu QIU ; Hailin SHEN ; Hailong SHANG ; Hongdi DU ; Lelin YU ; Fanghui ZHENG ; Ying CAO ; Fanghong ZHAO ; Ying WANG
Chinese Journal of Neuromedicine 2022;21(2):119-125
Objective:To investigate the evaluation value of one-stop whole-brain dynamic volume CT angiography and CT perfusion imaging (CTA-CTP) in the cynomolgus monkeys models of middle cerebral artery occlusion (MCAO).Methods:Ten adult cynomolgus monkeys were selected and examined by head and neck CTA-CTP and craniocerebral MRI to rule out craniocerebral space-occupying lesions or cerebrovascular malformation. Under guidance of digital substraction angiography (DSA), the right femoral artery was dissected and monkey autologous thrombosis was injected into the right middle cerebral artery (MCA) through microcatheter to prepare MCAO models. Whole brain DSA was performed intraoperatively to observe whether the model was successfully prepared, and head and neck CTA-CTP was performed 24 h and 7 d after modeling to determine the locations and brain blood flow changes of ischemic lesions. The monkeys were sacrificed 8 d after modeling, and the brain tissues were stained with 2,3,5-triphenyltetrazolium chloride (TTC).Results:Among the 10 cynomolgus monkeys, one was excluded because of preoperative cerebrovascular malformation, and one died of cerebral hernia caused by cerebral hemorrhage during the experiment. The remaining 8 MCAO models were successfully prepared. Intraoperative DSA orthography showed unclear M1 segment and distal branch of MCA. Brain CT scan 24 h and 7 d after modeling showed obvious cerebral ischemic lesions in the right MCA blood supply area, and the infarct extent 7 d after surgery was more obvious than that 24 h after surgery. CTA examination showed obvious blood flow interruption imaging in the in M1 segment of MCA on the right side, the distal vessels were not clearly displayed and the distal branches of the infarct side 7 d after surgery were obvious decreased as compared with those 24 h after surgery. CTP scan showed that the cerebral blood volume of the right cerebrum was obviously reduced as compared with that of the left cerebrum, which was consistent with the blood supply area of MCA; and the infarct cores and penumbra areas 7 d after surgery were obvious increased as compared with those 24 h after surgery. TTC staining showed that the ischemic lesions of the brain tissue on the slices were gray and involved multiple layers, and the range was roughly consistent with the infarction sites shown by DSA and CT imaging.Conclusion:One-stop whole brain dynamic volume CTA-CTP has good evaluation value in imaging findings in MCAO animal models.