OBJECTIVEThis study aims to evaluate the reliability and validity of the Chinese version of the chronic oral mucosal disease questionnaire (COMDQ).

METHODSUsing translation, back-translation, quality evaluation, cross-cultural adaptation, and pre-assessment, a Chinese version of the COMDQ was drafted. A 26-item instrument which comprised of four domains: pain and functional limitation, medications and side effects, social and emotional aspects, and patient support was designed and tested. This questionnaire was given to patients who visited our clinic. After the patients accomplished the questionnaires, we analyzed the collected data to evaluate the reliability and validity of the scale.

RESULTSA total of 130 patients were enrolled in our study. All the COMDQ questionnaires were completely filled out. The Chinese version of the COMDQ showed the following psychometric properties: Cronbach's alpha of 0.914, split-half reliability of 0.809, and correlation of 0.697. Factor analysis of construct validity demonstrated that the 26 items were classified into four domains, and the cumulative proportion was 67.62%. Thus, the scale had certain logical relation between the items in the same domains.

CONCLUSIONThe Chinese version of the COMDQ demonstrate good reliability and validity by rigorous psychometric properties. It can be widely used to test the oral health-related quality of life of patients with oral mucosal diseases.

China ; Humans ; Oral Health ; Psychometrics ; Quality of Life ; Reproducibility of Results ; Surveys and Questionnaires

OBJECTIVE:To study the effects and security of amlexanox oral coating for treatment of minor recurrent aphthous ulcer(MIAU). METHODS:A randomized double-blind experiment was carried on 42 patients with MIAU were randomly divided into experimental group(20 patients),and control group(22 patients),each group respectively administered with amlexanox coating and placebo,at the lesion site 4 times a day for 5 days.RESULTS:At 3 days,the effective rates of healing in the experimental and control group were 85.0% and 36.4%,respectively(P

Oral mucosal diseases, characterized by complicated etiopathogenesis, and various clinical manifestations, is closely related to various clinical medical disciplines as well as systemic diseases. These features, also known as the difficult points of oral medicine, contribute to the difficulty in learning and teaching. Holistic integrative medicine integrates the theory and technique of many subjects into a theoretical system combined with clinical medicine theory, molecular medicine frontier and psychosomatic treatment mode. This study explored the application and significance of holistic integrative medicine in the teaching of oral mucosal diseases, which can help deepen the understanding of principles and essences, cultivate students' network thinking model, and improve their ability to analyze and solve clinical problems.