1.Screening IgM and DNA for Mycoplasma pneumoniae in Children with Respiratory Infection
Hong FANG ; Xuexiang YANG ; Donglian CHEN
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To investigate the difference of IgM and DNA for Mycoplasma pneumoniae in respiratory infected children with different age.METHODS Serum samples were tested with ELISA for IgM and molecular beacon based real-time PCR was used to test M.pneumoniae DNA.RESULTS M.pneumoniae DNA was detected in 40% of the patients and the IgM was positive in 11% at the day of sampling and 30% after 7 days,respectively.The difference was of significance(P
2.The observation of NOSIE Used in schizophrenia patients
Hong YANG ; Yajuan LI ; Ming FANG
Chinese Journal of Behavioral Medicine and Brain Science 2001;10(1):72-73
Objective To show the condition that the NOSIE (Nurses' Observation Scale for Inpatient Evaluation) used in schizophrenia patients. Method To evaluate the male and female schizophrenia patients (paranoid type) by NOSIE. Results The total cases were 100 patients, male and female were both 50 cases. The result of evaluation showed that there was significant difference in 5 factors such as social competence, irritability, retardation, psychosis and depressive between male and female patients. As well, it matched with clinical information. The result of the consistency test for survey indicated that its Pearson coefficient of correlation for all of 7 factors in NOSIE were 0.617~0.843. Conclusion NOSICE can provided some objective data to clinical works of nurses. But, in other hand, its identity is lower.
3.Clinical Study on Genyou Yuyang Capsule for Treatment of 100 Cases of Hp-related Peptic Ulcer
Xingshan LIU ; Huixiang YANG ; Hong FANG ;
Journal of Traditional Chinese Medicine 1993;0(07):-
0.05), but the treatment group being higher than the control group.The adverse reaction rate was 3.0% in the treatment group and 40.9% in the control group with significant difference between the two groups(P
4.The predictive value of DWI for progression free survival in patients with cervix cancer after neoadjuvant chemotherapy
Hong ZHU ; Li ZHU ; Shiyu HAN ; Fang FANG ; Yang YU
Practical Oncology Journal 2014;(6):519-523
Objective To evaluate the predictive value of diffusion weighted imaging ( DWI) for progres-sion free survival(PFS)in patients with cervix cancer after neoadjuvant chemotherapy (NACT).Methods Thirty two consecutive patients with pathologically confirmed cervical cancer underwent MRI including DWI before and after NACT.Pathologic results and MR images were reviewed .Univariate analysis was applied by Kaplan -Meier method.The Cox proportional hazard model was used to evaluate prognostic variables for multivariate analysis .Re-ceiver operating characteristic ( ROC) curves were used to find optimal cutoff values of independent prognostic fac -tors for disease progression.Results Of 32 patients,10 had disease progression during follow -up period.In uni-variate analysis,FIGO stage,tumor size,the depth of tumor invasion,lymph node metastasis and ADC changes be-tween before and after neoadjuvant chemotherapy (ΔADC) were significantly associated with the disease progres-sion.In multivariate analysis , FIGO stage and ΔADC were the independent prognostic factors for PFS .Optimal cutoff values that determined by ROC curves analyses were FIGO stage ⅡandΔADC 0.31.Area under the ROC curve(AUC)of FIGO stage and ΔADC were 0.841(sensitivity 90.0%,specificity 68.2%)and 0.864(sensitivity 80.0%,specificity 81.8%),respectively.Conclusion In patients with cervix cancer after NACT ,FIGO stage andΔADC are significant predictive values for PFS .
7.Effects of glycyrrhizic acid beverage on exercise performance of fe- male undergraduates with moderate endurance training and its mechanism.
Jing QU ; Hong-fang YANG ; Xiao-hui WANG
Chinese Journal of Applied Physiology 2016;32(1):31-33
Beverages
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Exercise
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Female
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Glycyrrhizic Acid
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pharmacology
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Humans
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Physical Endurance
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Students
8.Screen and analysis of FVIII inhibitors in 167 hemophilia A patients.
Xiao-hong LIU ; Hua-fang WANG ; Rui YANG
Chinese Journal of Hematology 2011;32(9):627-629
Adolescent
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Adult
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Child
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Factor VIII
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genetics
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metabolism
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Hemophilia A
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blood
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diagnosis
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Humans
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Male
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Young Adult
9.Study on changes of protein kinase C activity in peripheral blood T lymphocytes of children with idiopathic thrombocytopenic purpura and its clinical significance
Chanlin WU ; Fang LIU ; Hong XIAO ; Qun CHEN ; Xiaomeng YANG
Chinese Journal of Clinical Laboratory Science 2006;0(01):-
Objective To investigate the changes of protein kinase C(PKC) activity in peripheral blood T lymphocytes of the children with idiopathic thrombocytopenic purpura (ITP) and the relationships between PKC activity and T lymphocytes activation and thrombocyte decrease.Methods Sterilized peripheral blood were collected from ITP children (n=35) and healthy children (n=30).T lymphocytes were isolated and purified by the T cell segregation enrichment column.The total PKC activity was detected by non-radioactive assay.FasL,the T cell activated marker,was determined by flow cytometer.Platelet count was performed by hematocytometer.Result Compared with healthy children,total PKC activity in ITP children was significantly enhanced (0.97?0.21 nmol/min.ml vs 0.60? 0.13 nmol/min.ml,?s,P
10.Association between MTHFRC677T,CBS844ins68 polymorphism and young ischemic stroke
Le FANG ; Tianwei WANG ; Yankun SHAO ; Hong YANG
Journal of Jilin University(Medicine Edition) 2006;0(02):-
Objective To investigate the genetic association of MTHFRC677T between CBS844ins68 polymorphism and young ischemic stroke.Methods The polymorphism of MTHFRC677T and CBS844ins68 in 98 stroke patients and 116 control subjects were examined and analyzed by using PCR-RFLP.Results The frequencies of two alleles were as follows: T allele 54.09%,C allele 45.91% in patients and T 37.93%,C 62.07% in controls(?2=11.18,P