Renal interstitial fibrosis represents the final common pathway of all chronic disease.The mechanism of renal interstitial fibrosis is very complex.It is not entirely clear now.The study found that epithelial-to-mesenchymal transition plays an important role in the renal interstitial fibrosis.Inhibition of epithelial-tomesenchymal transition may help to slow down the development and progression of renal interstitial fibrosis.The article mainly reviews the mechanism and treatment of epithelial-to-mesenchymal transition.

Thirty five samples of cows sera were assayed for human HBV serological marker with ELISA method. Sixteen samples were HBsAg and/or HBeAg positive,of which human HBV-like particles were found in 6 samples by immuno electron microscopic procedure. There were 1-3 precipitation lines between 5 concentrated samples and horse anti-HBs sera one of which fused with that of human HBsAg. In all the samples human sera polyalbumin receptor (PHSAR) was negative with ELISA method, and 32P-HBV DNA dot hibridization was also negative.

OBJECTIVE:To explore pharmacist's cognition on the factors affecting the drugstore-based pharmaceutical care(PC),and to discuss the relationship between the influencing factors and the influencing degree of these factors on pharmacists.METHODS:A questionnaire survey was carried out among pharmacists in drugstores in Xi'an city and a structural equation modeling(SEM)was formed to verify the factors affecting the drugstore-based PC.RESULTS:The questionnaire survey response rate was 84.7%(133/157).The data obtained fit the theoretical model satisfactorily.Partial of the hypotheses have been proved.CONCLUSIONS:According to SEM testing results,the development of trade were positively related to drugstore;drugstore has a direct positive impact on social evaluation,the practice of basic PC and advanced PC in drugstores;the quality of pharmacists has a direct positive impact on the social evaluation and the practice of advanced PC in drugstores.

Objective To investigate the distribution of authors,funding,institutions and regions of Chinese Journal of Orthopaedics between 2010 and 2015,understand the types and characteristics of authors＇ cooperation,identify the core author,core institutions and core regions,as well as evaluate academic level and journal quality from the view of literature citation.Methods According to Chinese Science Citation Database (referred CSCD) and bibliometric methods,we made statistical analysis,including the number of papers,cooperation,core authors,regional distribution of authors,systematic distribution of authors,productive institutions,funding sources and distribution.On the basis of Chinese science and technology journal citation reports (Compendex) from 2013 to 2015,the main indicators and coupling relationship of bone surgery journals were evaluated.Results From 2010 to 2015,Chinese Journal of Orthopaedics published 1 342 papers.There were 1 009 first authors,among which 802 authors (79.48％,802/1 009) published only one paper; 1 293 co-author papers contributed to 96.35％ cooperation rate and 5.69 degree of cooperation.Forty-nine papers (3.65％,49/1 342) had only one author,and 799 papers (59.54％,799/1 342) were published by affiliated Hospital,321 papers (23.92％,321/1 342) by provincial and municipal hospitals,138 papers (10.28％,138/1 342) by military hospital.There were 63 (6.24％,63/1 009) core authors publishing 252 papers (18.78％,252/1 342),and 20 productive institution publishing 630 papers (46.94％,630/1 342) in which Beijing was ranked at No.1 with 238 papers (17.73％,238/1 342).From 2010 to 2015,Chinese Journal of Orthopaedics publishing papers got 652 funding.From 2012 to 2014,its core total citations were 10 153,ranked No.1 in bone surgery journals in 2012 and ranked No.2 in 2013-2014; impact factors rose from ranked No.4 in 2012 to ranked No.2 in 2014,and the comprehensive evaluation of total score ranked No.1 in 2012-2014.Conclusion Chinese Journal of Orthopaedics has a strong team with a large number of authors,extensive source of institutions,a wide regional distribution,high cooperation rate,and strong ability to attract assistance funded paper.Affiliated Hospital and provincial and municipal hospitals are the main source of paper in the journal.Its core total citations,impact factor,subject diffusion index,academic impact indicators,comprehensive evaluation score were located in front rank of the same field of journals.

OBJECTIVE:To evaluate the influence of different process technics on the contents of catalpol in rehmannia root.METHODS:Dual wavelength TLC-scanning method was used to determine the contents of catalpol in different processed products of rehmannia root.RESULTS:There were significant differences in the contents of catalpol in the different processed products of rehmannia root and the crude herb.CONCLUSION:The contents of catalpol will be changed after processing with different processed methods and adding different supplementary materials.

OBJECTIVE:To study the current situation of development in personnel resources of licensed pharmacists of drug supply enterprises in China and the ways of development.METHODS:The existing problems in the development of per-sonnel resources of licensed pharmacists were analyzed through the ways of questionnaires and interviews.RESULTS&CONCLUSIONS:The drug supply enterprises lacked collocation and application rules of pharmacists and there lacked a system for employing,training,assessing and encouraging the licensed pharmacists.Furthermore,because of the inefficient policy,the supply-demand market of licensed pharmacists was unsatisfactory and the functions of the pharmacists were incomplete.Therefore,the practicing environment for the licensed pharmacists must be optimized.It is recommended that a perfect system of employment and assessment should be established;the full-time practice and the part-time practice should be allowed to coexist;the information network platform for supply-demand of the licensed pharmacists should be set up to improve the management as well as self-discipline function of licensed pharmacist association,better the further education system,and therefore promote the development of personnel resoures.

OBJECTIVE:To evolve the construction of laws®ulations of Chinese pharmaceutical care in drug?stores.METHODS:16sets of standardized documents were sorted and analyzed by a second order analytical method of litera?ture research.RESULTS&CONCLUSION:What Chinese pharmaceutical care of drugstores lacked were laws®ulations,the law order of the current laws®ulations need to be improved,meanwhile the contents of pharmaceutical care should be added to some regulations,and the guided regulations concerning the enforcement,checking and evaluation,monitoring and administration of pharmaceutical care items should be formulated,the pharmaceutical care work of Chinese drugstores should be promoted through the construction of legal system.

OBJECTIVE:To draw a comparison between domestic and foreign community pharmacies with regard to con?tents and form of pharmaceutical care research.METHODS:The related literature was retrieved and subjected to induction,generalization,comparison and analysis by reviewing and comparison.RESULTS&CONCLUSION:The pharmaceutical care research in community pharmacy abroad was abundant in theories,scientific in methodology,definite in objective,and substan?tial in content,which serves as a mirror for similar research in China.

Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Surgical Procedures ; adverse effects ; methods ; Postoperative Complications ; prevention & control ; Sleep Apnea, Obstructive ; surgery ; Treatment Outcome ; Uvula ; surgery ; Young Adult

Adhesives ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Endoscopy ; Epistaxis ; therapy ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome ; Young Adult