Objective To study the effect of Chinese medicine fumigation bath combined with acupuncture and hemorrhoids on improving the pain edema of elderly patients after anorectal pain.MethodsA total of 168 elderly patients with anorectal surgery were enrolled in our hospital from April 2013 to April 2016.The patients were randomly divided into two groups: the group (n=84) and the conventional treatment group (n=84) N=84).Routine treatment group given conventional Western medicine and potassium permanganate solution bath treatment, fumigation acupuncture group on the basis of conventional Western medicine treatment to give Chinese fumigation bath and acupuncture hemorrhoids treatment, compared the two groups of clinical efficacy, pain, Wound recovery and skin adverse reactions.ResultsThe total effective rate, no pain rate, edema disappearance time and wound healing time were 94.0%, 38.1%, (5.13±1.59) d, (16.47±4.06) d, respectively, compared with those in the conventional treatment group 84.5%, 22.6%, (6.74±1.23) d, (19.38±3.75) d, the difference was statistically significant (P<0.05).ConclusionChinese medicine fumigation bath combined acupuncture hemorrhoids acupuncture points can improve the local blood circulation, anti-bacterial anti-inflammatory pain, relieve senile patients after anorectal pain edema symptoms, speed up the rehabilitation process.

Carrying out reasonable classification of literature collection and analyzing the characteristics scientifically, the paper points out adjusting development policies for collection, constructing characteristic collection system and optimizing the quality of acquisition librarian, which would play an positive role in improving the construetion of literature resource system in libraries.

Signaling pathways of growth factors and their receptors not only diversify the biological behaviors in normal cells,but also play important roles in regulation of tumor cell proliferation,differentiation,transformation and migration.Aberrant expression of insulin-like growth factor-1 receptor (IGF-1R) has been observed in multiple hematological malignancies including multiple myeloma,lymphoma and leukemia.The existence of IGF-1R signaling pathway is a potential therapeutic target of hematological malignancies.This review summarizes recent findings of the aberrant expression of IGF-1R and therapeutic intervention in hematological malignancies.

Objective To study the clinical effect of combination of kurarinone and thymosin ?_1 for injection in treating chronic hepatitis B.Method One hundred and fifty-six patients with chronic hepatitis B were randomized into two groups,additional KR combined thymosin ?_1 for injection was given to treated group,and KR to control group.The therapeutic course for them was 6 months.We compared the serum ALT、 hepatitis B virological markers、T lymphocyte response before and 6 months after treatment.Results After treatment,the results showed that the levels of CD_3+、CD_4+、CD_4+/CD_8+ T cell in CHB patients of treatment were much higher than control groupnt.The ratio HBeAg and HBV-DNA loss were increased,the difference was significant(P

Objective To explore the relationship between dental trauma for children and their psychological behavior characteristics.Methods By using the method of case-control study,7-11 years of age children accepting oral health examination in our department were asked to fill in the questionnaire.The children without dental trauma were selected as the control group and the children with permanent tooth injury were selected as the injury group.Each group has 57 cases.All children finished the Eysenck personality questionnaire (EPQ) and their parents finished the Achenbach child behavior capacity list (CBCL).Results (1) The average CBCL score (32.51±20.41) and scores of P and N branch capacity lists in EPQ (44.72± 11.67,48.05± 12.39) of the injury group were all higher than those of the control group (17.19± 11.67,37.64± 8.17,41.40± 8.78) (P＜0.01).(2) The detecting rate of behavior problems in injury group was also higher than that of the control group (33.33％,7.02％,P＜0.01),OR=6.63,95％ CI =2.09-21.05.Boys of the injury group had higher scores than those in the control group in seven factors (depression,social withdrawn,restlessness,violation of discipline,attack,compel and social problems) (P＜0.05),and girls of the injury group also had higher scores than those in the control group did in three factors (depression,social withdrawn and attack) (P＜0.05).(3) In the injury group,boys had higher scores in the factor of schizoid anxiety than girls did (P＜0.01),risk factors were depression (OR=0.529,95％ CI =0.292-0.959),social withdrawn (OR=2.274,95％ CI =1.311-3.944),restlessness (OR=0.426,95％ CI =0.213-0.852),violation of discipline (OR=0.426,95％ CI =0.213-0.852) and attack (OR=0.644,95％ CI =0.459-0.903).However,girls had higher scores in the factor of depression than boys (P＜0.05),their risk factor was depression (OR=0.573,95％ CI =0.357-0.919).Conclusion There is a certain correlation between tooth injury and their psychological behavior characteristics of children.

Adenoma ; classification ; pathology ; Carcinoma in Situ ; classification ; pathology ; Carcinoma, Squamous Cell ; classification ; pathology ; Colorectal Neoplasms ; classification ; pathology ; Esophageal Neoplasms ; classification ; pathology ; Gastrointestinal Neoplasms ; classification ; pathology ; Humans ; Hyperplasia ; classification ; pathology ; Neoplasm Staging ; Precancerous Conditions ; classification ; pathology ; Stomach Neoplasms ; classification ; pathology ; World Health Organization

Breast ; pathology ; Carcinoma, Intraductal, Noninfiltrating ; diagnosis ; metabolism ; pathology ; Female ; Humans ; Hyperplasia ; metabolism ; pathology ; Keratin-5 ; metabolism ; Keratin-6 ; metabolism ; Precancerous Conditions ; diagnosis ; metabolism ; pathology ; Stem Cells ; metabolism ; pathology

Toll-like receptor (TLR) plays a crucial role in innate immune response and the subsequent induction of adaptive immunity. TLR is expressed on immune cells as well as epithelial cells and tumor cells. When endogenous and exogenous ligands bind with TLR, TLR signaling pathways are activated and a large number of inflammatory cytokines are released, creating an inflammatory microenvironment and leading to tumor formation, invasion and metastasis.

Objective]To summarize herbal medicine application regulation of Professor Wu Liangcun in gastric cancer treatment. [Methods]Collect 116 gastric cancer patients from Chinese medicine clinic system during January 1,2014 to December 31, 2014 and establish clinical prescription underlying database. Apply descriptive analysis to drug cumulative frequency, drug-induced taste and nature and apply cluster analysis to 42 drugs using more than 10 times. [Results] In the 116 gastric cancer patients,159 kinds of herbs were used ,the cumulative frequency of herbal medicine was 1816.GanCao was the herb with highest usage frequency, and then was FuLing, ShanYao, TaiZishen;According to accumulated frequency, herbs with tonifying function were at the top position(herbs with tonifying qi function were most), and then was the herbs with function of herbs with the function of clearing excessive heat, herbs with function of herbs with the function of relieving dyspepsia, herbs with function of herbs with the function of regulating qi. In terms of herbs' nature and taste, herbs with sweet taste, plain nature were used most. Cluster analysis divided all used herbs into 5 sections, involving prescriptions Sijunzi decoction, Erchen decoction, and couplet medicines DaoYa with GuYa, JiNeijin with MiHoutao, SheShecao with XianHecao and so on. [Conclusions] Professor Wu Liangcun treats gastric cancer with the law of tonifying qi, the main prescription is the same as Sijunzi decoction, emphasizing nourishing Yin and clearing away the heat-evil, protecting gastric, accompanied with promoting digestion and regulating qi.

Objective To investigate the clinical efficacy of gemcitabine in the treatment of elderly patients with advanced non-small cell lung cancer.Methods 50 patients in our hospital from January 2014 to September 2015 were selected as the research object, and were randomly divided into the control group and the experimental group, each group of 25 patients each.The patients in the control group were treated with special therapy, and the patients in the experimental group were treated with gemcitabine.The clinical indexes of the experimental group and the control group were compared and analyzed.Results After the treatment, the experimental group of 25 patients, 12 cases of patients with complete remission, 8 cases partial remission, 3 cases were stable, 2 patients progressed, the effective rate was 75%, clinical benefit rate of 92%.In the control group, 4 patients had complete remission, 2 patients had partial remission, 9 patients were stable, 10 patients progressed, the treatment efficiency was 24%, and the clinical benefit rate was 60%.The effective rate and the clinical benefit rate of the experimental group were significantly higher than that of the control group (P<0.05).1 years later, the survival rate of patients in the experimental group was 22, the survival rate was 88%, and the number of patients in the control group was 14.The survival rate of the experimental group was significantly higher than that of the control group, with statistical difference (P<0.05).Conclusion Gemcitabine monotherapy in the treatment of elderly patients with advanced non-small cell lung cancer can improve the therapeutic effect to a great extent, good safety, low incidence of adverse reactions, high survival rate, with further clinical promotion and application significance.