Breast Neoplasms ; pathology ; Female ; Humans ; Middle Aged ; Neoplasm Metastasis ; Neoplasms ; pathology ; Nose Neoplasms ; secondary ; Skin Neoplasms ; secondary

This paper analyzes the necessity of offering medical English courses at the preclinical stage,introduces the online medical English listening course,summarizes its characteristics:rich in content,highly interactive,quick in feedback,fair in assessment,and puts forward some suggestions for perfecting this course in the future.

Evaluation methods of chronic sinusitis ( Visual Analogue Score and Lund-Kennedy Score) were recom-mended by the 2009 Chinese Medical Association otolaryngology head and neck surgery to nasal Science Group,and retrospective analysis of the functional endoscopic sinus surgery for noninvasive fungal sinusitis treatment effect of 143 patients. VAS of preoperative was 5.8±1.0,postoperative score was 3.9±1.0, 2.4±0.9 after 3 months,6 months, respectively (P<0.01). Lund-Kennedy Score of preoperative was 7.7±2.1, postoperative score was 3.7±1.9, 1.6±1.4 after 3 months,6 months respectively (P<0.01).

Objective examine the current status of Science and Technology Novelty about Medicine and Health Sciences in the Guangzhou Military Region during 2010 to 2013.Methods Using Microsoft Excel software to conduct statistical analysis on data that including the novelty of the client' s new projects,subject classification,the level of project award application,client unit,type of requested projects,innovative items,etc.Results The total number of applying for project innovation checking showed a decreasing trend in the Guangzhou Military Region;the majority of awarded application was for the third Prize;and the requirested for new project innovation checking is far less than project innovation award checking.Conclusions The center should actively promote the understanding for the innovation of the new projects among the research groups,and improve the class of prize award.

Objective To explore the clinical value of combined detection of antiperinuclear fac-tor (APF) ,anti-RA keratin antibody (AKA) and anticyclic citrullinated peptide antibody (anti-CCP) in diagnosis and differential diagnosis of rheumatoid arthritis (RA). Methods Totally 119 RA pa-tients,101 non-RA rheumatisants and 39 healthy controls were enrolled in the study. Enzyme linked immunosorbent assay (ELISA) was applied to quantitately detecting anti-CCP antibody; immunofluo-rescence method was applied to quantitately determining AKA and APF. Then the quadruple tabular form was used to calculate the sensitivity and specificity. Results In RA group,the sensitivity of APF, AKA and anti-CCP antibody was 48.8% ,32.3% and 83.5% respectively; the specificity was 92. 2%, 93. 1% and 94.1 % respectively. Conclusion Three autoantibodies,including APF,AKA and anti-CCP antibody have high specificity in early diagnosis of RA. Combined detection of the three antibodies con-tributes to diagnosis and differential diagnosis of rheumatoid arthritis (RA).

How to acquire new tumor antigens is a hotspot in cancer research currently.According to the nature of antigen epitope binding its ligand,we can identify and get unknown antigen epitope even its amino acid sequence through some analytical techniques and experiments,from T lymphocytes and monoclonal antibody levels.So the molecular mechanisms of tumor immunity will be more distinct.

Objective To explore whether health examination save medical insurance fund or not. Methods To observe the sparing medical cost which 371 health examination people avoid repeated checking and shorten the length of stay during hospitalization from March 2006 to March 2007. To observe the effect of sparing medical cost because of regular health examination, early discovery diseases, pretreatment promptly and avoidance transforming to advanced diseases. Results Because of avoiding repeated checking and shortening the length of stay,everybody save the medical cost about 570 yuan,371 people can save about 21 ten thousands yuan. To statistics the average hospital cost of different courses of eight common diseases and malignant tumors from January to November at 2007, we discovered that the medical cost is large distinction between the earlier period and advanced stage of disease. For example: the medical cost of one stage of hypertension is 6608 yuan ,the two stage is 8838 yuan ,the three stage is 13 869 yuan, and the stage of hypertensive heart disease is 13 033 yuan. Parts of health examination crowd who stay at my hospital from 1996 were visited for five years ,we conformed many chronic diseases by prompt intervention can relieve and even reverse, avoiding the transformation to incurable disease which will consume a large number of strength and money. Conclusion Health examination resource is a medical treatment resource which isn't restricted by social security fund, the utilization can not only save medical cost but also discover and treat diseases earlier, thus we can save the strength and money before the advanced diseases.

Objective To evaluate the effects of preoperative sleep disturbance on the consumption of propofol during the period of general anesthesia and postoperative sleep quality.Methods Sixty-five patients scheduled for elective thyroidectomy surgery under general anesthesia were enrolled in the study.According to the preoperative Pittsburgh Sleep Quality Index (PSQI) score,the patients were divided into sleep normal group (n =33) and sleep disorder group (n =32).Anesthesia was induced and maintained with propofol given by closed-loop target-controlled infusion (CLTCI).The consumption of propofol during the period of general anesthesia,postoperative sleep quality in the evening of surgery and at 24 h after operation,and the painful levels of the patients at 1 d and 2 d after operation were compared between two groups.Results The totalconsumption of propofol in sleep disorder group [(1 024.33 ±213.02)mg] was more than that in sleep normal group [(892.25 ± 242.30) mg] (P ＜ 0.05),and the dosage of unit surface area per minute of propofol in sleep disorder group [(4.94 ± 0.80) mg/(min · m2)] was also more than that in sleep normal group [(4.45 ± 0.96) mg/(min · m2)] (P ＜ 0.05).Each group suffered from bad sleep quality in the evening of operation,and got improvement one day later (P ＜ 0.05).The sleep quality in sleep disorder group was improved after general anesthesia (P ＜ 0.05).Conclusions Preoperative sleep disturbance increased the consumption of propofol in the general anesthesia.General anesthesia can improve the sleep quality of the patients who suffered from sleep disorder.

Objective To evaluate the clinical value of cardiac troponin I(cTnI) in the diagnosis of myocardial ischemic injury.Methods Twenty patients were randomly divided into two groups: group I (cold crystalloid cardioplegia, n=10) and group Ⅱ (cold blood cardioplegia, n=10). The central venous blood samples were taken at various times during perioperation to measure the serum levels of cTnI,CK MB and CK . Myocardial samples were obtained 10 min before aorta clamping and 30 min after aotra unclamping, to observe myocardial ultrastructure .Results cTnI,CK and CK MB levels were normal before operation, increased markablely following aotra unclamping ,reached the peak 1 h after aorta unclamping to 24 h after operation, and decreased progressively to be normal in two groups. The serum cTnI level was significantly lower in group Ⅱ than that in group Ⅰ 24 h and 48 h after operation. The serum CK MB activity was lower in group Ⅱ than that in group Ⅰ 1 h after aorta unclamping. There was positive significant correlation between aorta cross clamping time and cTnI peak level.Conclusions cTnI can be used to evaluate the degree of myocardial injury and myocardial protective effect in open heart surgery during CPB. As indicators for reflecting the myocardial injury, the sensitivity and specificity of cTnI are more valuable than those of myocardial enzymes.

Health management is developing very fast as a new subject.The ethical problem in which there is rare in reports.Discussion about the ethical problems appears in health management and health examination,such as privacy protection,sex morality,excess service,healthy morality,humanities concern,cooperation between each section and so on,has a important actual significance.