1.Observation on the Effect of Acupoint Injection plus Massage Therapy on Primary Dysmenorrhea
Lixia Lü ; Meng Lü ; Yiwen FAN
Journal of Acupuncture and Tuina Science 2014;(4):256-259
Objective: To observe the clinical effects of acupoint injection therapy plus massage on primary dysmenorrhea (PD).
Methods: Ninety patients with PD were randomly divided into a treatment group or a control group, 45 cases in each group. The treatment group was treated by injection of Vitamin K3into Sanyinjiao (SP 6) plus massage on Diji (SP 8). The control group was treated by oral administration of Ibuprofen sustained-release capsule. Before and after the treatment, visual analogue scale (VAS) was adopted to assess pain degree of the patients. The therapeutic effects were observed after continuous treatment of three cycles of menstruation.
Results: After treatment, VAS scores were obviously decreased in both groups and the differences were statistically significant (allP<0.05). The difference in VAS score after treatment was more significantin the treatment group than that in the control group (P<0.01). The total effective rate was significantl higher in the treatment group than that in the control group (P<0.05).
Conclusion: Acupoint injection therapy plus massage for PD is effective and better than simple oral administration of Ibuprofen sustained-release capsule.
3.The expression of glial cell line-derived neutrophic factor and its effect on colonic transit function in slow transit constipation rats
Yanling LI ; Bin Lü ; Yihong FAN
Chinese Journal of Internal Medicine 2009;48(9):752-755
is of STC.Exogenous GDNF may improve the colon motor function by up-regulation of GDNF.
4.Analysis of the correlative factors of neonatal deaths in neonatology department
Fan WU ; Xi FAN ; Lü WANG ; Qiliang CUI
Chinese Journal of Neonatology 2017;32(3):169-175
Objective To analyze the correlative factors of neonatal deaths in neonatology department to improve the treatment level and reduce the death rate of the hospitalized newborn patients.Method The medical records and death review data of the infants who died in the neonatology department of the Hospital from 2009 to 2015 were retrospectively reviewed.They were assigned to three groups according to the therapeutic measures before their death,including comfort care group,do not resuscitate (DNR) group and active treatment group.Gestational age,birth weight,postnatal age at death and the direct cause of death were compared between groups by x2 test.Result A total of 337 infants were enrolled in this study.There were 112 cases (33.2%) in the comfort care group,73 cases (21.7%) in the DNR group and 152 cases (45.1%) in the active treatment group.Compared to the proportion of the different group during 2009-2012,the proportion of the comfort care group during 2013-2015 significantly increased(38.9% vs.27.2%,P =0.023),and the proportion of the active treatment group significantly decreased (38.3% vs.52.5%,P =0.009),while the proportion of the DNR group showed no significant difference (22.9% vs.20.4%,P =0.580).The proportion of the comfort care group was significantly higher in the group of neonates who died in early neonatal period than that in the late neonatal period and post-neonatal period (42.9% vs.9.3%,P <0.001),while the proportion of the active treatment group and DNR group decreased(17.9% vs.30.9%,P =0.009;39.2% vs.59.8%,P =0.001).The proportion the comfort care group increased with the decrcasing gestational age and birth weight (P =0.001 and 0.002).Of the 34 term infants,the top two principle causes of death were severe asphyxia (4.1.1%,14.cases) and congenital defects (32.4%,11 cases).Of the 303 preterm infants,the top three direct causes of death were neonatal respiratory distress syndrome (31.4%,95 cases),neonatal pulmonary hemorrhage (22.4%,68 cases) and congenital defects (6.3%,19 cases).Conclusion The proportion of comfort care and DNR was higher than the proportion of active treatment before the newborns' death and it was relative to gestational age and birth weight.Preterm infants were the predominant population of the infant deaths in the neonatology department.Neonatal respiratory distress syndrome was the principle cause of death in preterm infants,and severe asphyxia was the main cause of death in term infants.
5.Clinical study on parotidectomy with facial nerve dissection under microscope.
Yun-ping FAN ; Shao-yan FENG ; Ming-hui LÜ
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(8):685-686
Adolescent
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Adult
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Aged
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Facial Nerve
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anatomy & histology
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pathology
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Female
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Humans
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Male
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Microsurgery
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Middle Aged
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Parotid Neoplasms
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surgery
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Young Adult
7.Significance of HIF-1α, MVD and EGFR expression in detection of nasal inverted papilloma and clinical effect of taxol
Hao YANG ; Yang ZHANG ; Fang FAN ; Wei Lü ; Tianquan YANG
Chinese Journal of Immunology 2015;31(12):1683-1687
Objective:To explore the significance of the expression of HIF-1α,MVD and EGFR on diagnostic of nasal inverted papilloma and the clinical effect of taxol .Methods:The expression of HIF-1α,MVD and EGFR were detected by immunohistochemistry in nasal inverted papilloma .Results:The expression of HIF-1α,MVD and EGFR were enhanced with the degree of atypical hyperplasia in epithelium.The research also showed that the expression of HIF-1α,MVD and EGFR were increased dramatically in severe atypical hyperplasia with a significant statistical differences ( P<0.01 ) .The expression of EGFR and MVD showed a positive correlation with HIF-1α.The administration of Taxol alleviated the enhanced expression of HIF-1α, MVD and EGFR with a significant statistical difference(P<0.01),but with on statistical difference with moderately severe tissue (P>0.05).Conclusion:HIF-1α,MVD and EGFR are involved in the pathogenesis and deteriorate of nasal inverted papilloma and can be taken as biomarkers for the diagnosis of the dete -rioration of nasal inverted papilloma .
8.Discussion in measuring the curvature of cervical endplate based on reverse engineering software
Fan ZHANG ; Feizhou Lü ; Hongli WANG ; Jianyuan JIANG
Chinese Journal of Orthopaedics 2013;(6):621-627
Objective Method discussion of measuring curvature of cervical endplate based on reverse engineering software.Methods The CT scan images data (From C2 to C7) of 8 normal males were selected and inputted into Mimics 10.0 software for 3D reconstruction and separation (cervical spine is divided into C1-C7 isolated reconstructed 3D images).Another software NX Imageware 13.2 is used for further curvature measuring in lines named left,middle,right,anterior,middle,posterior which are derived from each superior and inferior endplate.In each line,15 different points which can perfectly show morphologic characters of the endplate are selected for statistic comparing between different points in the same endplate,different lines in the same endplate,different endplates in the same individual and the same endplate in different individuals.In addition,the correlation between the concavity and the width and depth of endplate is also analyzed.Results From inferior endplate of C2 to that of C6,except superior endplate of C7,there is significant difference between different points in the same line (P<0.05),while it is opposite in the compare between lines in the same endplate,different endplates in the same individual and the same endplate (except inferior endplate of C4) in different individuals (P>0.05).It showed significant correlation between the concavity and the width and depth of endplate.Conclusion Reverse engineering software is feasible to be used in evaluate morphologic characters of normal cervical endplate as a new method for measuring the detail parameters of them,it also explore the laws of the curvatures of cervical endplate initially and both of them will be of great use for cervical interbody cage design.
9.Clinical characteristics of 12 cases of chronic active Epstein-Barr virus infection
Xiaochun SHI ; Hongwei FAN ; Wei Lü ; Xiaoqing LIU
Chinese Journal of General Practitioners 2013;12(4):283-285
The medical records of all 12 patients diagnosed as chronic active Epstein-Barr virus (CAEBV) infection at our hospital were analyzed retrospectively.There were 7 males and 5 females with a median onset age of 28 years.CAEBV was characterized by fever,splenomegaly,hepatomegaly and lymphadenopathy,etc.The abnormalities of laboratory examination included liver dysfunction,thrombocytopenia,anemia and leucopenia.EBV-DNA detected by real-time polymerase chain reaction was (1.7 × 103-3.5 × 107) copies/μg DNA in peripheral blood mononuclear cell.Among them,the outcomes were death (n =5),lost to follow-up (n =2) and T cell lymphoma (n =1).It is necessary to improve our awareness of CAEBV infection because of its poor prognosis and high mortality.
10.Association between serum cystatin C and carotid atherosclerosis
Fan WEI ; Haiying Lü ; Xiaorong GAI ; Zhenjie WANG ; Zhenglai WU
Chinese Journal of Health Management 2013;(3):186-189
Objectives To evaluate the association between serum cystatin C and carotid atherosclerosis.Methods Medical data,including physical examinations,serum levels of cystatin C,bilirubin,uric acid and other biochemical markers and duplex ultrasonographic scanning for the carotid artery,of 1741 healthy adults (1193 men and 548 women) who sought physical check-up at Peking Union Medical College Hospital during January 2010 and December 2011 were collected,and those with hypertension,diabetes and liver or renal function failure were excluded.Based on the results of carotid duplex uhrasonography,all the adults checked were assigned to two groups,one with thickened intima-media and atherosclerotic plaque (group A),the other with non-thickened intima-media and non-atherosclerotic plaque (group B).Difference in serum cystatin C,bilirubin,uric acid and other biochemical markers between the two groups was analyzed by using Student's t test.The correlation between the markers and carotid plaque was analyzed by using Spearman correlation analysis.The correlated factors of the carotid thickness and plaque appearance were analyzed by using unconditional Logistic regression analysis.Results Serum level of cystatin C was significantly increased in group A (t =-8.85,P < 0.05).Thickness of carotid intima was positively correlated with serum cystatin C (r =0.21,P < 0.05).In multivariate Logistic regression analysis,high level of serum cystatin C was not an independent risk factor of carotid atherosclerosis.Conclusion Relationship between serum cyatatin C and carotid atherosclerosis was not confirmed in our populations,which should be explored further in cohort studies.