1.Tilt of IOLs and change of axial length in patients of posterior capsular opacification after Nd:YAG laser capsulotomy
International Eye Science 2017;17(8):1394-1398
AIM: To study the tilt of the intraocular lens (IOL) after Nd:YAG capsulotomy (YAG) and variation of the axial length (AL) in patients with posterior capsular opacification (PCO).METHODS: The study involved 18 eyes of 14 patients with PCO after uncomplicated phacoemulsification surgery and IOL implantation.All patients had taken examinations,including testing best corrected visual acuity (BCVA) by using standard logarithmic visual acuity chart,images of ocular anterior segment and AL by OCT.After the examinations,YAG was operated upon all patients.Each eye received one drop of Diclofenac Sodium Eye Drops immediately after YAG,and patients had taken examinations listed above again.One week later,BCVA and OCT were tested as well.Data (BCVA,tilt of IOLs,and AL) were recorded and analyzed statistically by SPSS.RESULTS: Mean patient age was 73.93±6.94y,including 5 males and 9 females,8 left eyes and 10 right eyes,altogether 14 patients with 18 eyes.In this study,tilt of IOLs was defined as the angle of anterior surface of IOL and pupil plane (briefly called Tilt,unit:°).Before YAG,mean Tilt was 2.896±2.286°,mean AL was 23.56±0.55mm.1h after YAG,mean Tilt was 4.702±2.991°,mean AL was 23.40±0.59mm,and BCVA enhanced 3.72±1.74 lines.1wk after YAG,9 patients with 12 eyes were involved in the study.The mean Tilt of these 12 eyes was 3.175±1.791° 1h after YAG and 3.434±1.835° 1wk after YAG.There were significant differences between Tilt before YAG and Tilt 1h after YAG.There were no significant differences between AL before YAG and AL 1h after YAG.There were no significant differences between Tilt 1h after YAG and Tilt 1wk after YAG.The lines of enhancement of BCVA 1h after YAG was correlated to differences between Tilt before YAG and Tilt 1h after YAG,of which the correlation coefficient was-0.523.CONCLUSION: IOLs of patients with PCO tilted after YAG,while AL rarely changed.After YAG,the less IOLs tilted,the more BCVA enhanced.
2.Relationship of visual function with the diagnosis and therapy of eye-related diseases——require for further research
Chinese Journal of Experimental Ophthalmology 2015;33(6):481-484
Visual cognition is a comprehensive procedure of information processing from eyes,visual pathway through cerebral cortex.Visual function covers down multiple concepts of ocular structures,psycophysics,photochemistry and photoelectric information transformation,reflecting visual acuity,contrast visual acuity,visual field,color vision,binocular vision,visual perception and many other detailed parameters.Ocular abnormal status is reflected to certain visual function while visual function is various and anfractuous from kinds of ocular problems.These complex networks lead to some misunderstanding of research in the filed of visual function concept.An expatiation of the diversified visual function is helpful for us to integrate visual function and ocular ailment process.This paper tried to explicit some misconceptions,and accentuated the importance of clinical research around visual function for the diagnosis and treatment of eye diseases and nervous system diseases.
3.The simulation and optimization of front window airflow in biological safety cabinets
China Medical Equipment 2016;13(6):17-18,19
Objective:In order to explore the maximum and the optimal velocity of front window air in biological safety cabinets and provide a scientific evidence for relevant test. Methods: As classⅡ biological safety cabinet an testing sample, computational fluid dynamics method is adopted to establish numerical model, then made the simulation of front window airflow. Results: The velocity relationship between front window airflow and the internal air has been confirmed. Conclusion:The maximum velocity of the front window flow is 1.4 m/s and the optimal velocity is 1.0 m/s. The tested data and conclusion can give some suggestions and reference for biological safety cabinets detection.
5.Laser-assisted outpatient septal spur surgery.
Fan LV ; Yang QIN ; Weining HUANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(5):306-307
OBJECTIVE:
The objective was to investigate the effectiveness of holmium-YAG laser-assisted septoplasty for septal deviations under local anesthesia.
METHOD:
All holmium-YAG laser-assisted septoplasty procedures performed at Beijing hospital (Beijing, China) between August 2009 and May 2012. These patients were operated upon in an outpatient surgical suite.
RESULT:
The success rate after surgery with regard to nasal obstruction (50 patients) is 92.0% (46 patients) of patients reporting remarkable improvement. Of the 32 patients with rhinologic headaches, A total of 28 subjects (87.5%) had their headache scores improved by 50% or more after surgery; nine (28.1%) were pain free at the last follow-up; four (12.5%) had a less than 25% reduction in their headache score. There were no patients with severe postoperative bleeding. There were no patients with septal perforation.
CONCLUSION
The holmium-YAG laser-assisted septoplasty is a useful approach to correct septal deviations. There is improved safety due to the enhanced viewing conditions and ample operating space during septal surgery, particularly in posterior septal spurs. The holmium-YAG laser-assisted septoplasty can limit the dissection to the area of deviation, thereby reducing postoperative swelling and the development of complications. It also has other advantages including lower medical costs, and faster return to full activity.
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Young Adult
6.Study on Methods for Population Size Estimation of HIV High Risk Groups and its Application in HIV/AIDS Situation Analysis in China
Peng XU ; Gang ZENG ; Fan LV ;
Journal of Medical Research 2006;0(05):-
Objective To investigate HIV high risk population size estimation method,analyze the epidemic situation in China and offer scientific evidence for policy making. Methods Appropriate methods to estimate different type high risk populations were ascertained by experimental study. Results Size estimation methods and procedures for different type high risk population were formed.Epidemic estimation and parameters fit for China were ascertained.HIV epidemic situation and characteristics were stated. Conclusion Methods formed in the study are the key points for the understanding of number of PLWHA,for the exact judgment of HIV epidemic,for the improvement of inspection system and examination work,for the formation of "Four Free and One Care".
7.Pharmacokinetics and Bioavailability of Lecithin-bound Iodine Capsules in Healthy Dogs
Guangjun FAN ; Qing FAN ; Huiyi LV ; Dongwei LENG
China Pharmacy 2001;0(07):-
0.05).The relative bioavailability of the lecithin-bound iodine capsules was 117.4%.CONCLUSION: The test and reference preparations of iodized lecithin were bioequivalent.
8.Effects of pamidronate on proliferation and differentiation of osteoblasts of rat
Fan-qing MENG ; Guo-liang LV ; Hong-yan WU ; Xiang LV
Chinese Journal of Rehabilitation Theory and Practice 2004;10(10):580-581
ObjectiveTo investigate effects of pamidronate on the proliferation and differentiation of osteoblasts of rats in vitro.MethodsOsteoblasts isolated from newborn rat calvaria were treated with various concentrations of pamidronate, the proliferation of osteoblasts was evaluated with the method of methyl thiazole tetrazolium (MTT) and activity of alkaline phosphatase (ALP) in medium was measured with kit of ALP detecting.ResultsThe proliferation of osteoblasts increased under the stimulation of Pamidronate range 10-6-M-10-12 M(P<0.05), but was inhibited at the concentration of high level (10-4 M). The activity of ALP decreased in the experiment.ConclusionPamidronate can act on the osteoblasts directly and increase the proliferation of bone cells, but inhibit the differentiation of the same cells.
9.Exploring bilingual teaching effectiveness in clinical medicine
Ruzhi DENG ; Jing ZHUGE ; Wanqing JIN ; Xinjie MAO ; Fan LV
Chinese Journal of Medical Education Research 2011;10(10):1262-1264
Bilingual teaching has become an important teaching method in the Higher Medical Education.The major of Optometry and Ophthalmology in Wenzhou Medical College is an organic integration of the modem western optometry and traditional ophthalmology,and also have the advantage of international education background.In the past twenty years,we have made positive practices and explorations in bilingual teaching.In this paper,we will take The Contact Lens Course ( National recconmentation course and National bilingual demonstration course ) for example to share the useful experiences and results,and to set an important model in spreading bilingual teaching for other clinical medicine disciplines.
10.Effect of Antler Peptides of Cervus Elaphus Yarkandensis on MC3T3-E1 Cells
Xiuhua LV ; Wei CHEN ; Fan ZHOU ; Fei LIU ; Jialin WU
Chinese Journal of Information on Traditional Chinese Medicine 2015;(2):47-50
Objective To evaluate the effect of antler polypeptides from Cervus elaphus yarkandensis on MC3T3-E1 cells. Methods The concentration of antler polypeptides of Cervus elaphus yarkandensis was measured by BCA protein assay kit. MC3T3-E1 cells were cultured and analyzed by BCIP/NBT chromogenic alkaline phosphatase (ALP) staining kit. After being induced to form mineralized knot, the cells were stained by using Alizarin red staining. Three different concentrations (10, 1.0, 0.1 μg/mL) of antler polypeptides were analyzed by MTT method and micronutrients enzymes standard method to determine the effect of cell proliferation and ALP synthesis. Results The concentration of antler polypeptides was 0.07 mg/mL. The results of in vitro cell activity analysis showed that the positive rate of ALP was 90%and the mineralization knot was stained red. Compared with the control group, the different concentrations of antler polypeptides all showed the function of cell proliferation and the effect was dose-dependent after 3 d and 7 d. Compared with the control group, at the 3 d, three groups of antler polypeptides promoted synthesis and secretion of ALP (P<0.01) and the results showed a dose-dependent effect. Conclusion Antler polypeptides could obviously promote the proliferation of MC3T3-E1 cells and secretion of ALP, which indicated that antler polypeptides have certain effect on osteoporosis.