1.Association of Early-Life Famine Exposure with Metabolic Dysfunction-Associated Fatty Liver Disease and Fibrosis in Adulthood.
Ran WEI ; Hong Yan QI ; Lin LIN ; Yuan Yue ZHU ; Yi ZHANG ; Jie ZHANG ; Xue Yan WU ; Chun Yan HU ; Shuang Yuan WANG ; Hong LIN ; Yu XU ; Min XU ; Yu Fang BI ; Wei Qing WANG ; Jie Li LU ; Guang NING ; Yu Hong CHEN
Biomedical and Environmental Sciences 2022;35(6):558-562
Adult
;
Age Factors
;
China
;
Famine
;
Female
;
Fibrosis
;
Humans
;
Liver Diseases
;
Prenatal Exposure Delayed Effects
;
Sex Factors
2.Analysis of gene products induced by phosphate starvation in enteric bacteria.
In A DOH ; Tae Yoon LEE ; Sung Kwang KIM
Journal of the Korean Society for Microbiology 1992;27(6):517-524
No abstract available.
Enterobacteriaceae*
;
Starvation*
3.Anorexia Nervosa with Autonomic Dysfunction.
Chang Seop KIM ; Poong Lyul RHEE ; Jae Joon KIM ; Kwang Cheol KOH ; Jong Chul RHEE ; Kyoo Wan CHOI
Korean Journal of Gastrointestinal Motility 1998;4(2):139-143
Anorexia nervosa is characterized by distortion of body image and profound weight loss due to self starvation. So, the patients are easily diagnosed with history and interview. We experienced a patient who had suffered for prolonged vomiting and profound weight loss without definite distorted body image, but had accompanied by autonomic dysfunction. Thus, we report a case with a brief review of literatures.
Anorexia Nervosa*
;
Anorexia*
;
Body Image
;
Humans
;
Starvation
;
Vomiting
;
Weight Loss
4.A Case of Hypoglycemia following Cesarean Section .
Young Hwa MOON ; Chang Jae KWON
Korean Journal of Anesthesiology 1978;11(3):279-281
Little has been reported concerning post-operative hypoglycemia in previously asymptomatic individuals. Post-operative hypoglycemic coma is one of the most perplexing problems and must be differentiated from other conditions accompaning coma. We experienced a case of hypoglycemia following emergency cesarean section in primigravida with cephalopelvic disproportion on the fourth post operative day. The comatous state appeared abruptly and developed repeatedly. The causes of post-hypoglycemic coma are discussed and the prolonged starvation before and after operation was suspected to be the cause of coma.
Cephalopelvic Disproportion
;
Cesarean Section*
;
Coma
;
Emergencies
;
Female
;
Hypoglycemia*
;
Pregnancy
;
Starvation
5.An Analysis on Legal Autopsy Under 1Year of Age.
Han Young LEE ; Kyung Moo YANG ; Jae Kwon KIM ; Shin Mong KANG
Korean Journal of Legal Medicine 2003;27(2):17-22
This is a statistical analysis based on the data of legal autopsies under 1 year of age performed at the Headquarters of the National Institute Scientific Investigation, requested from law enforcement agencies from 1996 to 2000. This report aims to analyse various aspects of 530 unusual deaths under 1 year of age in Korea, chiefly Seoul and its surrounding area. Male was 55.8% and female was 44.2%. Unnatural deaths were 39.6%, natural 53.4%, and the unknown 7.0%. Homicide occupied 66.7% in unnatural death and asphyxia was 41.4%, starvation and neglect 35.0%, and trauma 20.7% in homicide. Smothering was the leading cause of asphyxial homicide and accidental death. Natural death including perinatal disorders, sudden infant death syndrome and congenital malformations was the main cause of death in this age group.
Asphyxia
;
Autopsy*
;
Cause of Death
;
Female
;
Homicide
;
Humans
;
Korea
;
Law Enforcement
;
Male
;
Seoul
;
Starvation
;
Sudden Infant Death
6.FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases.
Kook Hwan KIM ; Myung Shik LEE
Diabetes & Metabolism Journal 2014;38(4):245-251
Fibroblast growth factor 21 (FGF21) is an endocrine hormone that is primarily expressed in the liver and exerts beneficial effects on obesity and related metabolic diseases. In addition to its remarkable pharmacologic actions, the physiological roles of FGF21 include the maintenance of energy homeostasis in the body in conditions of metabolic or environmental stress. The expression of FGF21 is induced in multiple organs in response to diverse physiological or pathological stressors, such as starvation, nutrient excess, autophagy deficiency, mitochondrial stress, exercise, and cold exposure. Thus, the FGF21 induction caused by stress plays an important role in adaptive response to these stimuli. Here, we highlight our current understanding of the functional importance of the induction of FGF21 by diverse stressors as a feedback mechanism that prevents excessive stress.
Autophagy
;
Fibroblast Growth Factors
;
Homeostasis
;
Insulin Resistance
;
Liver
;
Metabolic Diseases*
;
Mitochondria
;
Obesity
;
Pharmacologic Actions
;
Starvation
7.A Case of Primary Cutaneous Mucormycosis in a Immunocompetent Patient.
Ho Youn JO ; Chong Hyeok KIM ; Young Chul KYE ; Soo Nam KIM
Korean Journal of Dermatology 1995;33(3):546-550
Mucormycosis is an infectious disease caused by fungi of the order Mucorales. Almost all patients have a serious uriderlying condition such as diabetes mallitus, imrnunosuppression, starvation, burn, but a few cais have been reported in previously heilthy subjects. In order to successfully treat this infection, diagnosis must be prompt and acior. panied by aggressive debridement and parenteral administration of amphotericin B. We report a case of primary cutaneous mucormycosis in 58-year-old man. The lesion was a well-circumscribed erythematous plaque with central necrcis Histopathologically, a biopsy revealed broad, nonsptate with branches occuring at right anghles.
Amphotericin B
;
Biopsy
;
Burns
;
Communicable Diseases
;
Debridement
;
Diagnosis
;
Fungi
;
Humans
;
Middle Aged
;
Mucorales
;
Mucormycosis*
;
Starvation
8.Identification of Differentially Expressed Genes from Serum Deprived p388D1 Cells.
Su Young KIM ; Sang Ho KIM ; Sug Hyung LEE ; Nam Jin YOO ; Jung Young LEE ; Choo Soung KIM
Korean Journal of Pathology 1998;32(7):488-493
This experiment is designed to find differentially expressed genes in p388D1 cells that are specific for the serum deprived state. Serum starvation induces cells to enter the quiscent state in the cell cycle and is used to arrest cell growth or synchronize the cell cycle. Differential display and ribonuclease protection assay were used to identify quantitative change in gene expression. Nineteen genes that showed a differential expression in the differential display were cloned and 7 clones were verified by a ribonuclease protection assay. Among the 7 clones clone-16 showed same expression pattern in comparison with the differential display. Deduced amino acid sequences of clone-16 had N-glycosylation motif and seems to be a secretory protein. Getting a full sequence of clone-16 is critical for the characterization of it.
Amino Acid Sequence
;
Cell Cycle
;
Clone Cells
;
Gene Expression
;
Ribonucleases
;
Starvation
9.The Statistical Analysis on Legal Autopsy Performed in Korea during 2012 Year.
Joo Young NA ; Jong Pil PARK ; Hye Jin PARK ; Bong Woo LEE ; Young Shik CHOI ; Joong Seok SEO
Korean Journal of Legal Medicine 2013;37(4):198-207
This statistical analysis of 4,709 legal autopsies performed in Korea in 2012 was conducted to obtain primary data about and related variables. The analysis revealed the following: 1. Of the total number of deaths, men accounted for and women, 26.8%. Evidently, the number of deaths among men was more than twice that among women. 2. With respect to mode of death, 54.8% were recorded as unnatural deaths, 39.2% were natural deaths, and 6.0% had unknown causes. Of the 2,581 unnatural deaths, 44.8% were accidental deaths; 27.2%, suicidal; 17.5%, homicidal; and 10.3%, undetermined. 3. Of the total number of unnatural deaths, 43.0% were trauma-related deaths, for which falling down was the leading cause, accounting for 33.5% cases. Asphyxiation was accounted for 17.2%, among which the predominant cause was hanging (55.3%). Moreover, 12.5% of deaths were due to drowning; 11.5%, poisoning; 11.2%, thermal injuries; 2.7%, complications in medical procedures; and 0.3%, electrocution, starvation, or neglect. 4. Among 1,847 natural deaths, heart diseases accounted for 50.2% and vascular diseases accounted for 16.7%. 5. There were 207 cases of deaths among children under the age of 10, of which 94 were unnatural and 49 were homicidal deaths. Of all cases, 9.2% had an unknown cause of death, and of these 67.6%, were putrefied or skeletonized bodies.
Autopsy*
;
Cause of Death
;
Child
;
Drowning
;
Female
;
Heart Diseases
;
Humans
;
Korea*
;
Male
;
Poisoning
;
Skeleton
;
Starvation
;
Vascular Diseases
10.Effects of Starvation and Perioperative Fluid Therapy on the Blood Glucose Concentrations during Anesthesia in Children.
Ill Sook SUH ; Sun Ok SONG ; Dae Pal PARK
Yeungnam University Journal of Medicine 1984;1(1):89-93
This study included 38 children patients of less than 4 years old and 18 kg body weight. After 8 hours of starvation, the children were divided into 2 groups: Group I received Hartmann's solution and Group II received Hartmann's dextrose solution. In both groups, the rates of infusion were 10 ml/kg/hr before and during operation and blood samples were collected just before and 1 hr after induction of anesthesia, respectively. The results were as follows; 1) In the Group I, blood glucose concentration just before induction was decreased than control values that was checked at ward, and 1 hr value after induction was significantly increased then control values. 2) In the Group II, blood glucose concentration was increased just before and 1hr after induction than control values significantly respectively. 3) In the blood glucose concentration 1 hr after induction, difference between Group I and Group II was not significant. 4) In children, duration of starvation about 8 hrs did not significant influence on blood glucose concentration although dextrose was not administered.
Anesthesia*
;
Blood Glucose*
;
Body Weight
;
Child*
;
Fluid Therapy*
;
Glucose
;
Humans
;
Starvation*