Botulium toxin A has been used therapeutically in humans for over 20 years for a variety of medical indications. Some wrinkle and unsightly facial expressions are due to hyperkinetic muscle. For the past year, the author has injected it for variant purpose, so we describe the our experience with the variant extended use of the toxin including correction for just dynamic wrinkle, used with subperiosteal face lifting or peeling, post-traumatic twitching, and facial paralysis and relevant anatomy are discussed. Also we have another concept about muscle anatomy which have superficial and deep portion. The superficial portion is for harmonious action with SMAS during facial expression, which is also related to fine wrinkle, and the deep portion play role gross movement. Botulium toxin is safe and effective in varient field without complication. Its use is associated with a high degree of patient and physician satisfaction.
Exotoxins* ; Facial Expression ; Facial Paralysis ; Humans ; Rhytidoplasty

OBJECTIVES: Emotion perception deficit has long been suggested to be one of the core features of schizophrenia. Although there have been several studies examining responses to facial expressions, few studies addressed music emotion recognition. The aim of this study was to examine the difference in emotion recognition in music between normal subjects and patients with schizophrenia. METHODS: Twenty pieces of music were presented to 43 patients with chronic schizophrenia and 82 healthy controls. The set of music consisted of ten pieces of sad music and ten pieces of cheerful music. The subjects were asked to answer whether each piece of music was sad or cheerful. RESULTS: The correct response rate of music emotion recognition was lower in patients with schizophrenia compared with that in healthy controls (76.67+/-19.03% vs. 93.54+/-8.18%, p<0.001). When subgroup analyses was done by type of music ('sad' or 'cheerful'), patients showed a significantly lower correct response rate in recognizing both sad and cheerful emotion in music than healthy controls (sad emotion : 65.12+/-31.15% vs. 91.95+/-15.27%, cheerful emotion : 88.0+/-16.83% vs. 95.12+/-8.64%). The significant correlations between the clinical symptom severity of schizophrenia and music emotion recognition were not found to be. CONCLUSION: The results suggest that patients with schizophrenia might have difficulties in recognizing musical nuances.
Facial Expression ; Humans ; Music ; Schizophrenia

Möbius syndrome is a rare congenital condition, characterized by abducens and facial nerve palsy, resulting in limitation of lateral gaze movement and facial diplegia. However, to our knowledge, there have been few studies on evaluation of cranial nerves, on MR imaging in Möbius syndrome. Herein, we describe a rare case of Möbius syndrome representing limitation of lateral gaze, and weakness of facial expression, since the neonatal period. In this case, high-resolution MR imaging played a key role in diagnosing Möbius syndrome, by direct visualization of corresponding cranial nerves abnormalities.
Cranial Nerves ; Facial Expression ; Facial Nerve ; Magnetic Resonance Imaging ; Paralysis

OBJECTIVES: In recent years there has been a discernible increase of interest in facial expressions as a tool for affective neurosciences research which investigates the neural circuit for emotional perception and control. Though substantial researches have documented the universality of several emotional expressions, researches have shown evidences for cross-cultural differences of facial emotion recognition. Therefore the need for facial expressions of Koreans is gathering strength. Thus we developed the images of facial expressions of Korean people as a research tool for affective neurosciences and standardized them. METHODS: Three professional actors and three actresses were participated in this study (two in their twenties, two in their forties, two in their sixties). They were asked to pose each of the following facial expressions in turn: happiness, sadness, fear, anger, disgust and surprise. And facial emotion identification test was done for one hundred common person to get percent of judgment of each emotion and intensity ratings for each photographs. RESULTS: Six facial expressions in each subject were obtained. Among six emotions, subjects performed better on the recognition of happiness and worse on the recognition of fear and disgust. Also, each emotion term was presented with a 9-point (0-8) scale on which subjects rated. All emotion terms displayed 4.7-7.0 point scale. CONCLUSION: We could obtain facial expressions of Koreans for happiness, sadness, fear, anger, disgust, surprise and neutral, and then standardized them. As a tool for affective neurosciences, it can be used for the investigation of neural circuit for emotion recognition and control.
Anger ; Facial Expression* ; Happiness ; Humans ; Judgment ; Neurosciences*

OBJECTIVES: In recent years there has been a discernible increase of interest in facial expressions as a tool for affective neurosciences research which investigates the neural circuit for emotional perception and control. Though substantial researches have documented the universality of several emotional expressions, researches have shown evidences for cross-cultural differences of facial emotion recognition. Therefore the need for facial expressions of Koreans is gathering strength. Thus we developed the images of facial expressions of Korean people as a research tool for affective neurosciences and standardized them. METHODS: Three professional actors and three actresses were participated in this study (two in their twenties, two in their forties, two in their sixties). They were asked to pose each of the following facial expressions in turn: happiness, sadness, fear, anger, disgust and surprise. And facial emotion identification test was done for one hundred common person to get percent of judgment of each emotion and intensity ratings for each photographs. RESULTS: Six facial expressions in each subject were obtained. Among six emotions, subjects performed better on the recognition of happiness and worse on the recognition of fear and disgust. Also, each emotion term was presented with a 9-point (0-8) scale on which subjects rated. All emotion terms displayed 4.7-7.0 point scale. CONCLUSION: We could obtain facial expressions of Koreans for happiness, sadness, fear, anger, disgust, surprise and neutral, and then standardized them. As a tool for affective neurosciences, it can be used for the investigation of neural circuit for emotion recognition and control.
Anger ; Facial Expression* ; Happiness ; Humans ; Judgment ; Neurosciences*

OBJECTIVE: It was proposed that the ability to recognize facial emotions is closely related to complex neurocognitive processes and/or skills related to theory of mind (ToM). This study examines whether ToM skills mediate the relationship between higher neurocognitive functions, such as reasoning ability, and facial emotion recognition. METHODS: A total of 200 healthy subjects (101 males, 99 females) were recruited. Facial emotion recognition was measured through the use of 64 facial emotional stimuli that were selected from photographs from the Korean Facial Expressions of Emotion (KOFEE). Participants were requested to complete the Theory of Mind Picture Stories task and Standard Progressive Matrices (SPM). RESULTS: Multiple regression analysis showed that the SPM score (t=3.19, p=0.002, beta=0.22) and the overall ToM score (t=2.56, p=0.011, beta=0.18) were primarily associated with a total hit rate (%) of the emotion recognition task. Hierarchical regression analysis through a three-step mediation model showed that ToM may partially mediate the relationship between SPM and performance on facial emotion recognition. CONCLUSION: These findings imply that higher neurocognitive functioning, inclusive of reasoning, may not only directly contribute towards facial emotion recognition but also influence ToM, which in turn, influences facial emotion recognition. These findings are particularly true for healthy young people.
Facial Expression ; Humans ; Male ; Negotiating ; Theory of Mind*

Emotional information is critical for our social life, in which attentional bias is now a focus in the study on attention. However, the attentional bias processing mechanism of emotional faces still arouses huge controversy. Using similar experimental paradigms and stimuli, the published studies have yielded contradictory results. Some studies suggest that angry faces could automatically stimulate attention, that is, there is an anger superiority effect. On the contrary, lines of growing evidence support the existence of a happiness superiority effect, suggesting that the superiority effect is shown in happy faces rather than angry faces. In the present paper, the behavioral and neuroscience studies of anger and happiness superiority effects are combined. It is found that there are three major reasons for the debate over the two types of effects, which include the choice of stimulus materials, the difference of paradigm setting, and the different stages of emotional processing. By comparatively integrating the previous published results, we highlight that the future studies should further control the experimental materials and procedures, and investigate the processing mechanism of anger and happiness superiority effects by combining cognitive neurobiology means to resolve the disputes.
Anger ; Attentional Bias ; Facial Expression ; Happiness ; Humans

BACKGROUND AND OBJECTIVES: A number of surgical procedures exist to improve facial symmetry for patients with facial paralysis. Whereas static symmetry is often improved, dynamic asymmetry frequently persists because of the imbalance of complex coordinated movements of facial expression. The paralyzed face is often distorted by the excessive pull of the normal contralateral face during emotional expression. We report the use of botulinum toxin in patients with facial paralysis to improve lower facial asymmetry by limiting the excessive pull of contralateral face. SUBJECTS AND METHOD: Ten adult patients with unilateral facial paralysis were included in this study. Patients had injections at contralateral facial muscle which were zygomaticus major, levator labii superioris and depressor angularis orii. The effectiveness of the botulinum toxin injections on facial symmerty and patient appreciation of this were assessed by measuring the level difference of both mouth angles and difference in the distance from the midline to both mouth angles before and 1 month after injection. Also patients were asked to fill up the questionnaire about the magnitude of effect and any related side effects of injection at 1 month follow up. RESULTS: Botox injection decreased the level difference of both mouth angle and difference of distance from midline to both mouth angles in patients with unilateral facial paralysis at full-denture smiling. Five of ten patients were reported as moderate to marked improvement in expressive facial asymmetry after botulinum toxin injection into normal lower face. CONCLUSION: Botulinum toxin injection is a useful ancillary technique for improving dynamic facial asymmetry of the paralyzed face.
Adult ; Botulinum Toxins* ; Facial Asymmetry ; Facial Expression ; Facial Muscles ; Facial Paralysis* ; Follow-Up Studies ; Humans ; Mouth* ; Surveys and Questionnaires ; Rehabilitation* ; Smiling

The Melkersson-Rosenthal syndrome consists of the associated of indings of facial nerve paralysis, facial swelling and scrotal tongue. We report a case of MRS where a 20 year old female had diffuse swelling on her face and lips for 10 years. This was also accompaiined with difficulty of facial expression and fissured tongue. The improved with intralesional injection: of triamcinolon acetonide 40mg for 3 consecutive weeks and 2 every other week.
Facial Expression ; Facial Nerve ; Facial Paralysis ; Female ; Humans ; Injections, Intralesional ; Lip ; Melkersson-Rosenthal Syndrome ; Tongue, Fissured ; Young Adult

The goals of ideal lip reconstruction in chronic facial palsy include recovery of sphincteric function of the lip and symmetry of mouth during facial expression and the resting state. The lip reconstruction in chronic facial palsy can be mainly divided into dynamic and static method. Recently, the dynamic lip reconstruction tend to be reported more frequently with the development of microsurgery. From December of 1994 to August of 2001, We had 6 dynamic lip reconstruction by one or two staged free neurovascular flap, and followed up from 1 to 4 years and 4 months (mean 36 months). One case was two-staged free rectus abdominis flap after cross-face nerve graft with sural nerve. Another case was one- staged free gracilis muscle flap anastmosised with one of the buccal branch of facial nerve in the affected side, which had relatively good function. The other 4 cases were one-staged free neurovascular latissimus dorsi flaps. We also combined other procedures such as gold implant for lagophthalmos, temporalis muscle transfer on ectropion of the lower eyelid, and the excisional eyebrow lift on the affected side. We got relatively satisfactory results except 1 case.
Ectropion ; Eyebrows ; Eyelids ; Facial Expression ; Facial Nerve ; Facial Paralysis* ; Lip* ; Microsurgery ; Mouth ; Rectus Abdominis ; Superficial Back Muscles ; Sural Nerve ; Transplants