2.Curative effect analysis of ultrashort wave combined with dephlogisticate cholagogue table in treating patients with chronic cholecystitis
Chinese Journal of Postgraduates of Medicine 2012;35(18):28-30
Objective To evaluate the clinical effect of ultrashort wave combined with dephlogisticate cholagogue table in treating patients with chronic cholecystitis.Methods One hundred and forty-four patients with chronic cholecystitis treated from January 2009 to October 2011 were randomly divided into 2gtoupe by mechanical sampling method.Treatment group (76 cases) was treated with ultrashort wave and dephlogisticate cholagogue table.Control group (68 cases) was treated with dephlogisticate cholagogue table.The therapeutic effect and the incidence of ache and fever and B-type ultrasonography between two groups were compared.Results The total effective rates were 89.5% (68/76) in treatment group and 67.6%(46/68) in control group.There was significant difference (P <0.01).The incidence of ache and fever,positive rate of B-type ultrasonography in tneatment group [10.5%(8/76),5.3%(4/76),10.5%(8/76)] were significantly lower than those in control group [32.4% (22/68),14.7% (10/68),33.8%(23/68)] (P < 0.05).Conclusion Ultrashort wave combined with dephlogisticate cholagogue tabble is an effective method for treating chronic cholecystitis.
3.Biological markers of esophageal carcinoma invasion and metastasis
Journal of International Oncology 2011;38(10):774-776
The invasion and metastasis of esophageal carcinoma is associated with several tumor marker on oncogenesi and tumor development,including matrix metalloproteinase,cell adhesion molecules CD44,pituitary-tumour transforming genes.Studies have shown that these tumor markera are over-expression in esophageal carcinoma,which affect the progress and prognosis of esophageal carcinoma,and their specificity and value for clinical application need to be futher studied.
4.Expression and clinical significance of survivin and p63 in diffuse large B-cell lymphoma
Journal of Leukemia & Lymphoma 2010;19(4):219-221
Objective To investigate the expression and significance of survivin and p63 in diffuse large B-cell lymphoma (DLBCL). Methods Immunohistochemical staining was used to detect the expression of survivin and p63 in the lymphnode tissues from DLBCL patients and lymph node reactive proliferation.Results The positive expression rate of p63 and survivin proteins in DLBCL patients was 63.5 %(33/52) and 76.9 %(40/52), respectively. p63 was not expressed in lymph node reative proliferation. The positive expression rate of survivin in lymph node reactive proliferation was 20.0 %. The expression rates of survivin and p63 between two groups was significant different. The replase rate of groups with positive expression of survivin and p63 were higher than that of the negative groups. The mean survival in groups with positive expression of survivin and p63 were shorter than that of the negative groups. Conclusion Survivin and p63 are useful in therapeutic and prognostic assessment. Patients with poor prognostic can be screened out in the early period of treatment using expression of survivin and p63, which may help to improve the outcome of diffuse large B-cell lymphoma.
5.Reliability and validity of Chinese version of the Medication Adherence Self-efficacy Scale
Chinese Journal of Practical Nursing 2015;31(20):1502-1505
Objective To translate the English version of the Medication Adherence Self-efficacy Scale (MASES) into Chinese and to test the reliability and validity of the Chinese version of MASES in patients with hypertension.Methods Totally 285 patients with hypertension were recruited and were investigated by the Chinese version of MASES.The results underwent analysis for reliability and validity.Results The retest reliability of MASES was 0.843.The Cronbach α of the Chinese version of MASES was 0.876.The Cronbach α of the four dimensions ranged from 0.794 to 0.905.The average content vality index (CVI) of the scale was 0.946.Factor analysis got four factors,which explained 68.683% of the total variance.The factor loading of each item on its common factor was >0.4.Conclusions The Chinese version of MASES has been proved to be reliable and valid.It can be used as a valid tool for the measurement of the patient compliance in patients with hypertension.
6.Reliability and validity of Chinese version of the Oncology Patients' Perceptions of the Quality of Nursing Care Scale
Chinese Journal of Practical Nursing 2015;31(23):1770-1773
Objective To translate the English version of the Oncology Patients' Perceptions of the Quality of Nursing Care Scale (OPPQNCS) into Chinese and to test the reliability and validity of the Chinese version of OPPQNCS in oncology patients.Methods The English version of OPPQNCS was translated by Brislin translation mode.Totally 320 oncology patients were recruited and were investigated by the Chinese version of OPPQNCS.Results The internal consistency coefficient of the Chinese version of OPPQNCS was more than 0.70,ranged from 0.804 to 0.964;the test-retest was 0.826.The content validity index(CVI) was 0.845-1.000,the average CVI was 0.925.Factor analysis got four factors,which explained 78.548% of the total variance.And every objective factor loading were greater than 0.4.Conclusions The Chinese version of OPPQNCS has been proved to be reliable and valid.It can be used as a valid tool for the oncology patients to measure their perceptions of the quality of nursing care they got.
7.Association between serum uric acid levels and prognosis in acute ischemic stroke:a prospective case study
Chinese Journal of Geriatrics 2015;34(11):1210-1212
Objective To investigate the association between serum uric acid (SUA)levels and outcome in acute ischemic stroke.Methods A total of 388 acute ischemic stroke patients were included in the prospective case study.Data on demographic characteristics, risk factors for life style, history of disease, the admission SUA and outcome at discharge were collected for all participants.Results Mean serum uric acid levels were (284.5±83.6) μmol/L in the normal uric acid? group, and(455.3±78.1)μmol/L in the high uric acid group(P<0.01).There were significant differences in National Institutes of Health Stroke Scale (NIHSS) score at two weeks between the high UA group and the normal UA group [(11.0±6.0) vs.(11.0±5.3),P=0.048], and also in early neurological improvement (P=0.048).A significant difference was found in serum uric acid level between patients with good versus poor neurological function outcome (P =0.045).Conclusions There is the association between admission serum uric acid levels and outcome in acute ischemic stroke.Elevated serum uric acid level predicts a lower chance of a poor outcome in acute ischemic stroke.
8.Effect of different nutritional status of elderly patients with rectal cancer before surgery on postoperative reha-bilitation
Journal of Regional Anatomy and Operative Surgery 2016;25(5):379-381
Objective To summarize the prognosis of elderly patients with colorectal cancer excision who were divided into different groups by the nutritional status before their surgery.Methods In our hospital,100 patients (age from 64 to 70)with colorectal cancer were performed the screening of nutritional risk by NRS2002 before surgery.Patients with score from 1 to 2 were as the group A,and patients with score over 3 were as group B.The related indexes and recovery between two groups were compared.Results The NRS2002 rating scale score showed that 76 patients were at nutritional risk,37 cases among them received nutrition support and had faster recovery of intestinal function the time of tube pulled out after operation[(1.8 ±0.4)d vs.(2.9 ±1.5)d],exhaust time[(2.4 ±0.6)d vs.(4.3 ±0.9)d],time of in-take food[(2.9 ±0.5)d vs.(4.5 ±1.1)d],length of stay[(10.8 ±0.9)d vs.(14.1 ±1.3)d],incidence of infection related complica-tions (0 vs.5.13%),the differences were statistically significant(P <0.05).Conclusion Problems exist in varying degrees of loss of nu-trition in elderly colorectal cancer patients before surgery,an objective assessment of the extent and targeted care and nutritional support can significantly improve the postoperative nutrition and to facilitate recovery of gastrointestinal function after surgery.
9.The application of serum endotoxin combined with integrated model for end-stage liver disease in evaluating the short and medium term prognosis of patients with decompensated liver cirrhosis
Chinese Journal of Postgraduates of Medicine 2014;37(31):18-21
Objective To evaluate the application value of serum endotoxin combined with integrated model for end-stage liver disease (iMELD) in evaluating the short and medium term prognosis of patients with decompensated liver cirrhosis.Methods The clinical data of 68 patients with decompensated liver cirrhosis were retrospectively analyzed.The patients were divided into survival group and death group according to the result of follow-up at the 3,6 and 12 months.The iMELD score and Child-Turcotte-Pugh (CTP) score were calculated according to relevant indicators,and the serum endotoxin level was detected.The correlation between serum endotoxin and iMELD score was analyzed in the short and medium term prognosis in patients with decompensated liver cirrhosis.Results After 3 months' follow-up,5 patients died.The iMELD scores in survival group and death group were (39.26 ± 7.29) and (49.29 ± 8.63) scores,CTP scores were (9.32 ± 2.12) and (12.03 ± 2.75) scores,serum endotoxin levels were (9.21 ± 2.24) and (15.39 ± 5.12) ng/L,and there were statistical differences (P < 0.05).After 6 months'follow-up,12 patients died.The iMELD scores in survival group and death group were (41.35 ± 8.03) and (52.18 ± 10.37) scores,CTP scores were (9.78 ± 2.05) and (12.93 ± 1.99) scores,serum endotoxin levels were (8.96 ± 2.41) and (16.43 ±6.03) ng/L,and there were statistical differences (P <0.05).After 12 months' follow-up,19 patients died.The iMELD scores in survival group and death group were (40.74 ± 6.38) and (52.29 ± 8.53) scores,CTP scores were (10.01 ± 2.23) and (13.27 ± 1.69) scores,serum endotoxin levels were (8.53 ± 2.34) and (16.52 ± 6.08) ng/L,and there were statistical differences (P < 0.05).The area under curve of receiver operating characteristic (ROC) was 0.952,standard error was 0.048,and 95% confidence interval was 0.790-1.022.The best critical value of iMELD score to predict death was ≥48.00 scores,and the risk of death would rise if iMELD score was increased.The best critical value of serum endotoxin to predict death was ≥ 11.00 ng/L.Conclusion iMELD score and serum endotoxin have important value in predicting prognosis in patients with decompensated liver cirrhosis.
10.Study on the stability of limited intercarpal arthrodesis of scaphoid-trapezium-trapezoid
Chinese Journal of Orthopaedics 2000;0(11):-
0.05). No loosening, distortion and breaking of fusion apparatus were found. Conclusion STT arthrodesis simulated in new fusion apparatus does not show displaced even though forced the utmost movement in range of motion of extension 35?/flexion 50?, radial deviation 10?/ulnar deviation 30?. STT arthrodesis can get excellent stability using new fusion apparatus.