In the study, 25 consecutive eyes of 25 patients (21 men, 4 women; mean age: 45 ± 8.5 years; range 30 to 58 years) with central serous chorioretinopathy were examined with optical coherence tomography (OCT) during acute phase and after the resolution of the retinal detachment. Cross-sectional retinal images through the center of the fovea were obtained from all eyes by OCT. The retinal thickness at the fovea center was measured. All of patients were conducted fluorescent angiographies. In the acute phase, neurosensory retina was thickened within the area of serous retinal detachment in all 25 eyes. The retinal thickness at the center of the fovea during the acute phase (range, 162 to 273µm; mean ± SD, 192 ±18 µm) was significantly thickened in comparison with that after resolution (range, 98 to 149 µm; mean± SD, 117±12.7µm). The retinal pigment epithelium was focally detached in five eyes
Eye Diseases ; Diagnosis

Saccadic eye movement may be difined entirely on the basis of velocity-amplitude characteristics. Despite the obvious importance of saccadic peak velocity measurements, there is lack of agreement about saccadic velocity-amplitude relationships in general and particularly with regard to the direction of movement. The variability of the results is attributed mostly to different recording techniques used and partly to the sample size. The aim of this study is to investigate the effect of saccadic direction for the determination of their possible influence upon the horizontal saccadic peak velocity. Therefore, six basic patterns of horizontal saccadic movement were determined and the direction and velocity of these basic patterns of the angular distance of 10 degrees were recorded and discussed. The experimental apparatus consisted of Biometrics Eye Movement Monitors, target function generators, oscillographic recorders and the other fixation devices. The experimental subjects were three healthy Korean adults. All experiments had been performed in the dark room for 4 weeks. The position and peak velocity of saccadic eye movement in the records were carefully observed and the data were analyzed statistically for significant change with the use of t-test at the 5 per cent level and the main results are as follows: 1. In the horizontal saccadic eye movement in the angular distance of 10 degrees, the production rate of undershoot or corrective movement is low and most of the saccadic eye movement are normal. 2. The mean of the saccadic peak velocity is 295.6 deg/sec in the angular distance of 10 degrees. 3. The mean horizontal saccadic peak velocity is faster in the nasal direction, as compared with the temporal direction, but the difference is not statistically significant. 4. The mean saccadic peak velocity is greater in the nasal than in the temporal direction among the velocities of the centering, decentering and symmetry but the difference is not statistically significant. 5. The analysis of the results showed that the mean horizontal saccadic peak velocity has no statistically significant difference between the nasal and the temporal direction in the angular distance of 10 degrees. Author feels that the methods and results of this study may be useful tools in the diagnosis and research of eye disease related to the nervous system and that further study to establish the standard data of saccadic peak velocity should be performed at the various angular distances.
Adult ; Diagnosis ; Eye Diseases ; Eye Movements ; Humans ; Nervous System ; Saccades* ; Sample Size

No abstract available.
Child ; Cornea/*abnormalities ; Cysts/*diagnosis ; Eye Abnormalities/*diagnosis ; Eye Diseases/*diagnosis ; Female ; Humans ; Visual Acuity/physiology ; Vitreous Body/*pathology

Myiasis is most prevalent in Mexico, central and south America, tropical Africa, and the southwestern United States. Although dermal myiasis is rare in most of the United States, it is a disorder that may be seen in international travelers. In the United States, external myiasis is usually caused by the cattle botfly. We report here a case of ophthalmomyiasis involving the left upper eyelid of a child. We examined a six-year-old boy who presented to the Massachusetts Eye and Ear Infirmary (MEEI) in September 1998. He complained of persistent swelling of his left upper eyelid for the previous ten days. The edema and erythema were unresponsive to warm compresses and oral antibiotics. Ocular examination revealed a mild preseptal cellulitis of the left upper eyelid with a small draining fistula. On slit-lamp examination, we found one larva protruding intermittently from the fistula site. The larva was extracted with forceps, wrapped in a moist towel and sent in a jar to the parasitology laboratory. The specimen was identified as a Cuterebra larva by a parasitologist at the Harvard School of Public Health. One week later, the patient's eyelid edema and erythema had completely resolved.
Animal ; Case Report ; Child ; Diagnosis, Differential ; Diptera* ; Eye Infections, Parasitic*/surgery ; Eye Infections, Parasitic*/parasitology ; Eye Infections, Parasitic*/diagnosis ; Eyelid Diseases/surgery ; Eyelid Diseases/parasitology* ; Eyelid Diseases/diagnosis ; Eyelids/parasitology* ; Human ; Larva ; Male ; Myiasis*/surgery ; Myiasis*/parasitology ; Myiasis*/diagnosis

Rheumatic diseases are associated various extra-articular manifestations, such as eye, nerve, pericardium, and pleura. The anterior part of the eye has distinguished anatomic structure resembling synovial joints, thus it is a common site of ocular manifestation in rheumatic disease. These changes include sicca syndrome, peripheral ulcerative keratitis, episcleritis, scleritis, and iritis. Some of these findings may be the clues for the diagnosis of the rheumatic diseases, and some ocular manifestations may represent the activity or prognosis of the rheumatic diseases. These ocular complications may leads to severe visual loss. It is crucial to rule out underlying systemic diagnosis in rheumatic disease associated ocular diseases, and when diagnosed, the coordination of the rheumatologist with the ophthalmologist in the treatment is imperative.
Corneal Ulcer ; Diagnosis ; Eye Diseases* ; Iritis ; Joints ; Pericardium ; Pleura ; Prognosis ; Rheumatic Diseases* ; Scleritis ; Sjogren's Syndrome

Amelanotic melanoma is a subtype of malignant melanoma that lacks clinically visible pigmentation. The absence of recognizable pigmentation obscures the clinical hallmark of the more typical form of malignant melanoma. Because it mimics various non-pigmented benign and malignant skin diseases, clinicians have difficulty diagnosing this lesion. An incorrect or delayed diagnosis can result in a worse outcome because the prognosis of melanoma depends on the tumor thickness and tissue invasion at the time of diagnosis. Therefore, early diagnosis is crucial for treating amelanotic melanoma. Dermoscopy is a useful non-invasive technique for diagnosing not only pigmented skin lesions, but also non-pigmented skin lesions because this modality can visualize vascular structures that are not discernible to the naked eye. Analyzing the dermoscopic vascular structures of amelanotic melanoma helps make an early diagnosis. We report here on a case of amelanotic melanoma for which the diagnosis was aided by performing dermoscopy as an adjuvant tool.
Delayed Diagnosis ; Dermoscopy ; Early Diagnosis ; Eye ; Melanoma ; Melanoma, Amelanotic ; Pigmentation ; Prognosis ; Skin ; Skin Diseases

Adolescent ; Adult ; Dermatitis, Occupational ; diagnosis ; Eye Diseases ; diagnosis ; etiology ; Female ; Humans ; Male ; Trichloroethylene ; poisoning ; Young Adult

The aim of this study was to investigate the feasibility of anterior segment optical coherence tomography to assess the anterior segment morphology of hyperopia in school-aged children. 320 eyes of 160 school-aged children, 6-12 years of age, were examined with anterior segment optical coherence tomography and were divided into four groups according to the cycloplegic spherical equivalence of refractive error. The mentioned four groups were: emmetropia group, low hyperopia group, moderate hyperopia group and high hyperopia group. The measurements of central corneal thickness, anterior chamber depth, angle opening distance, trabecular iris space area and scleral angle were compared in pairs among objects in the four groups. The results showed that high hyperopia and moderate hyperopia had shallower anterior chamber depth and narrower anterior chamber angle compared to those in emmetropia group. The study also showed that anterior segment optical coherence tomography as a non-contact technology could become a new technology for accessing the anterior segment morphology of hyperopia in school-aged children.
Anterior Chamber ; pathology ; Child ; Eye Diseases, Hereditary ; diagnosis ; Humans ; Hyperopia ; diagnosis ; Tomography, Optical Coherence

PURPOSE: To report the experience of treating chronic granulomatous canaliculitis induced by permanent silicone punctal plugs used for dry eye syndrome treatment. METHODS: The transformation of puncta below both eyes and secretions in the lacrimal duct were observed for a 56-year-old female patient who had attended hospital for 4 months due to epiphora and secretions. Under the diagnosis of lacrimal duct inflammation for the lower lacrimal duct of both eyes, three-snip punctoplasty, curettage in the lacrimal duct, and pathological examination on the part of the lacrimal duct obtained from the three-snip punctoplasty were carried out. RESULTS: The lacrimal silicone plugs were removed from the lacrimal duct at the time of the lacrimal duct curettage, and a diagnosis was made based on tissue biopsy of chronic granulomatous canaliculitis induced by permanent silicone punctal plugs. After the above surgical operations, the epiphora and the anterior eye segment symptom both disappeared. CONCLUSIONS: The permanent silicone punctal plug used to permanently close the lacrimal punctum scarcely causes disorder in the lacrimal drainage system with epiphora and inflammation by acting as a foreign substance. It therefore should only be used when essential.
Anterior Eye Segment ; Biopsy ; Curettage ; Diagnosis ; Drainage ; Dry Eye Syndromes ; Female ; Humans ; Inflammation ; Lacrimal Apparatus Diseases ; Middle Aged ; Silicones* ; Canaliculitis

Herpes simplex virus keratits(HSK) is one of the most common external eye diseases that cause corneal blindness, Therefore early diagnosis and proper treatment of HSK are essential. However it is frequently misdiagnosed because it shows non-specific corneal lesion than other infectious corneal disease. And also diagnosis of HSK mostly rely on clinical examination and patient history. We evaluated suspicious HSK patients by indirect immunofluofluorescent(IF) antibody test and analyzed its efficacy in the early diagnosis of HSK. Among 47 patients(47 eyes), 37 patients were suspicious heretic keratitis and others not. Dendritic keratitis patients existed in 17 out of 37 patients and they were evaluated with virus culture and indirect IF test. The result of indirect IF test was confirmed under the immunofluorescent microscope and for virus culture the specimens were inoculated on Vero cells(monkey kidney cells). The positive results of indirect IF test was 28 out of 37 suspicious HSK patients and 1 out of 10 non-suspicious HSK patients. Dendritic HSK patients showed IF positive in 15 out of 17 patients(82.3%). Sensitivity of indirect IF test in suspicious HSK patients was 75.7%(2837) and 88.2%(15/17) in dendritic HSK patients. Indirect IF test was all positive(14/14) in dendritic HSK patients that showed culture positive. From these results, indirect IF test has a high sensitivity in early diagnosis of HSK and might be ussful as a rapid diagnostic tool in HSK patients.
Blindness ; Corneal Diseases ; Diagnosis ; Early Diagnosis ; Eye Diseases ; Herpes Simplex* ; Humans ; Keratitis ; Keratitis, Dendritic ; Keratitis, Herpetic* ; Kidney ; Simplexvirus