The eye dry syndrome is increasingly and a difficult problem in the ophthalmology. There were about 15% of people over 60 years experienced the eye dry of which 10% must be treated. This disease usually considered because initial mild symptoms. However, these symptoms can lead eye burn that can not be treated. The superficial corneitis with severe pain and vision loss occurred subsequently. The corneal and conjunctival surface usually protected from chemical component, mechanical agent, microbial and virus and film of aqueous humor as a first barrier.
Dry Eye Syndromes ; Eye Burns

During 2 years (1993-1994), 46 children with 66 burnt eyes due to lime (46.8%) were treated. Internal therapy and surgical procedure were described. Results were evaluated and recommendations were given
Eye Burns ; lime ; Child

Burns, Chemical ; Eye Burns ; Humans ; Hydrogen Sulfide ; Male ; Occupational Injuries

Limbal stem cell transplantation (Limbal transplantation) is a surgical technique of ocular epithelial transplantation advocated for a variety of Ocular surface disorders with presumed stem cell deficiency- especially chemical injury of the eye. We report 2 cases (2 eye) of chemical injury successfully treated by limbal autologous transplantation in 1998. The value, indications, complications and prospect of this procedure are discussed.
Stem Cell Transplantation ; Eye Burns ; therapeutics

Adolescent ; Adult ; Burns, Chemical ; Eye Burns ; Fisheries ; Humans ; Hydrogen Sulfide ; Middle Aged ; Occupational Injuries ; Young Adult

PURPOSE: To report a case of Charles Bonnet syndrome in a patient who developed phantom vision of an enucleated eye. The patient had lost her vision because of a chemical burn 10 years previously. CASE SUMMARY: A 37-year-old woman received enucleation of one eye because ocular pain and phthisis had developed due to a chemical burn that occurred 10 years previously. On the first postoperative day, she complained of phantom vision in the enucleated eye. The image she described was like sparkling bubbles. She had recognized the image was not real, and no psychological problems were found during pre- and postoperative periods. Her wound state was good, so she is currently wearing an artificial eye, though her phantom vision intermittently returns. She has adapted to her phantom vision such that she now rarely feels discomfort. RESULTS: Charles Bonnet syndrome is a visual hallucination that occurs among the blind or those who are visually impaired. Besides ophthalmologic care, sociological and psychological care should be considered.
Adult ; Burns, Chemical ; Eye ; Eye, Artificial ; Female ; Hallucinations ; Humans ; Postoperative Period ; Vision, Ocular

OBJECTIVETo observe the expression of laminin and fibronectin in alkali-burned corneas in rats.

METHODSA total of 18 normal Wistar rats were randomly divided into 6 groups (n = 3 in each group). For each rat, one eye was injured by alkali burn, the other one was taken as the normal control. Then all the corneas were surgically removed and the expression of laminin and fibronectin was observed with immunohistochemistry respectively at 7 hours, 1 day, 3 days, 7 days, 14 days and 28 days after alkali burn.

RESULTSCompared with that of the normal controls, the expression of laminin and fibronectin of the burned eyes was dramatically higher at 7 hours, reached peak at 14 days and decreased to the normal level at 28 days after alkali burn.

CONCLUSIONSIn the process of wound healing after alkali burn, the expression of laminin and fibronectin increases dramatically, which suggests that laminin and fibronectin may participate in the process of corneal wound healing.

Animals ; Burns, Chemical ; metabolism ; Corneal Injuries ; Eye Burns ; metabolism ; Fibronectins ; metabolism ; Immunohistochemistry ; Laminin ; metabolism ; Rats ; Rats, Wistar ; Wound Healing ; physiology

Alkalies/therapeutic use* ; Burns, Chemical/drug therapy* ; Corneal Injuries/drug therapy* ; Eye Burns/drug therapy* ; Humans ; Taurine

PURPOSE: To evaluate the efficacy of continuous drug delivery system using microinfusion pump by animal study METHODS: Schirmer test was performed after connecting the microinfusion pump at the superior fornix of rabbit eye. The pump was settled to instill artificial tears. We also evaluated the efficacy of continuous 0.1% fluorometholone infusion after alkali burn induced by 1N NaOH. RESULTS: Average change in Schirmer tear test value was 12.0mm/5min. The recovery after alkali burn was improved in the eye of continuous infusion of steroid eye drops. CONCLUSIONS: Microinfusion pump was thought to be useful as a continuous eye drops delivery system. It would be applicable to infuse artificial tears continuously in severe dry eye patients and to infuse antibiotic eye drops in infectous eye disease patients.
Alkalies ; Animals ; Burns ; Drug Delivery Systems ; Eye Diseases ; Fluorometholone ; Humans ; Ophthalmic Solutions ; Tears

OBJECTIVETo investigate the H(2)S pollution in cabins which caused the fishermen's eye burns.

METHODSFifty-six fishing boats' H(2)S concentration was surveyed and 56 fishermen's eyes were inspected. The air samples were collected from 21 fishing boats' cabins, where the eye burns took place and the monitoring conditions met the inspection requirement, in order to confirm the concentration of H(2)S when eye burns and the systemic poisoning happened. Thirty fishing boats were divided into two groups: one was using air ventilating and spraying, the other was using naturally ventilation to find out the effective method of dispersing H(2)S. Five fishing boats were surveyed in which the fishermen had slight symptom of bulbar conjunctiva hyperemia and cough to find out the minimum concentration of H(2)S which caused the eye burns and respiratory mucosa.

RESULTSAmong 56 fishermen who were surveyed, 46 fishermen's eyes (92 eyes) burnt and they were from 21 vessels, 10 of them (20 eyes) were moderate, 36 of them (72 eyes) were light. The concentration of H(2)S in the 21 fishing boats' cabins which caused eye burns was (99 ± 38) mg/m(3). The first measuring of the concentration of H(2)S in the 30 fishing boats in which fish were not discharged yet was (219 ± 31) mg/m(3). Air ventilating and spraying group's concentration of H(2)S was (213 ± 24) mg/m(3), while that of naturally ventilation group's was (225 ± 36) mg/m(3). Dispersing after 1 hour, the concentration of H(2)S of air ventilating and spraying group was (21 ± 3) mg/m(3), the decreased concentration was (192 ± 21) mg/m(3), fell 90%; the concentration of naturally ventilation group was (184 ± 36) mg/m(3), the decreased concentration was (41 ± 8) mg/m(3), fell 18%. The difference between the two groups' decreased concentration was significant (t = 25.627, P < 0.05). The threshold value of H(2)S concentration that could cause the eye burns was 38 mg/m(3)(exposure time 120 min). In 7 vessels, the concentration of H(2)S in the cabins was (123 ± 9) mg/m(3) where 10 fishermen's moderate eye burns happened. In other 7 vessels, the concentration of H(2)S in the cabins was (54 ± 7) mg/m(3) where 19 fishermen's light eye burns happened. The difference of H(2)S concentration between the two groups was significant (t = 14.236, P < 0.05).

CONCLUSIONHigh H(2)S concentration and long exposure time in cabin can cause serious eye burns. The bilge air ventilation and inner cabin spraying are the effective method to clear the H(2)S in cabin within short time.

Air Pollutants, Occupational ; analysis ; Confined Spaces ; Eye Burns ; epidemiology ; etiology ; Fisheries ; Humans ; Hydrogen Sulfide ; analysis ; Ships