The research on the relationship between single exposure and health outcomes is not comprehensive without a capability of systematically revealing the cause. At present, some studies have explored the relationship between exposome and health outcomes. However, due to the large data of exposome and the correlation among exposure factors, there is still a lack of effective methods to analyze the relationship between exposome and health outcomes. This study reviews the previous literature, combs the analysis methods of the relationship between exposome and health outcomes, and points out that agnosticism combined with middle-level information can significantly reduce the false positive rate, so as to provide a reference for accurately identifying the influencing factors of health outcomes in extensive exposome.
Exposome ; Humans ; Outcome Assessment, Health Care