1.Parathyroidectomy for refractory secondary hyperparathyroidism with severe bone disease.
Evora Teodora Amor N ; Mirasol Roberto C
Journal of the ASEAN Federation of Endocrine Societies 2012;27(1):105-108
Advances in the medical management of secondary hyperparathyroidism due to renal failure have decreased the use of parathyroidectomy as a treatment option. However, some patients with end-stage renal disease still progress to refractory hyperparathyroidism and debilitating bone disease, for which parathyroidectomy may be warranted. We describe a case of a 35-year-old female on chronic hemodialysis who presented with bone pains, deformities, decrease in height and recurrent pathologic fractures. She had markedly elevated parathyroid hormone (PTH), vitamin D deficiency, persistent hyperphosphatemia and hypocalcemia despite therapeutic measures. Subtotal parathyroidectomy was done with eventual improvement of biochemical abnormalities, resolution of bone pains and healing of fractures.
Human ; Female ; Adult ; Bone Diseases ; Fractures, Spontaneous ; Hyperparathyroidism, Secondary ; Hyperphosphatemia ; Hypocalcemia ; Kidney Failure, Chronic ; Parathyroid Hormone ; Parathyroidectomy ; Renal Dialysis ; Renal Insufficiency ; Vitamin D Deficiency