1.Risk of Subsequent Events in Patients With Minor Ischemic Stroke or HighRisk Transient Ischemic Attack
Keon-Joo LEE ; Dong Woo SHIN ; Hong-Kyun PARK ; Beom Joon KIM ; Jong-Moo PARK ; Kyusik KANG ; Tai Hwan PARK ; Kyung Bok LEE ; Keun-Sik HONG ; Yong-Jin CHO ; Dong-Eog KIM ; Wi-Sun RYU ; Byung-Chul LEE ; Kyung-Ho YU ; Mi-Sun OH ; Soo Joo LEE ; Jae Guk KIM ; Jun LEE ; Jae-Kwan CHA ; Dae-Hyun KIM ; Joon-Tae KIM ; Kang-Ho CHOI ; Jay Chol CHOI ; Eva LESÉN ; Jonatan HEDBERG ; Amarjeet TANK ; Edmond G. FITA ; Ji Eun SONG ; Ji Sung LEE ; Juneyoung LEE ; Hee-Joon BAE ;
Journal of Korean Medical Science 2022;37(33):e254-
This study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ≤ 5) or high-risk TIA (acute lesions or ≥ 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% at 3 months and 16.7% at 1 year. Incidence rate of stroke or death in the first month was 12.5 per 100 person-months: highest in patients with large artery atherosclerosis (17.0). The risk of subsequent events shortly after a minor AIS or high-risk TIA was substantial, particularly in patients with large artery atherosclerosis.