This study analyzes the career trajectories of students from Jeonuigam in the late nineteenth centry Joseon dynasty, shedding light on its educational functions by focusing on individuals listed in the Jeonhamsaengdoan and Byeoncheonpalsean. The primary subject of this research, the Jeonhamsaengdoan, is a valuable resource for understanding the career paths of Jeonuigam students, containing enrollment information for 384 individuals. The Byeolcheonpalsean, introduced for the first time in this paper, provides information about an alternative method of enrollment known as ‘Byeolcheon’ for students entering Jeonuigam.The analysis of these individuals’ career paths reveals that many Jeonuigam students had overlapping enrollments in other technical institutions, such as Saekwon and Gwangsangam. This suggests that medical education was not limited to specific disciplines but was part of a broader educational framework. Moreover, the Seogyeong system allowed younger siblings to enroll alongside older ones, while the Byeolcheon system, which facilitated recommendations from other institutions, provided educational opportunities for families. These findings highlight the diverse methods in which medical and vocational education were conducted in the late nineteenth century Joseon dynasty.Approximately 66 percent of Jeonuigam students became medical officials, while others pursued careers in fields such as interpreting and various government roles, contributing to society in multiple ways. This study demonstrates that Jeonuigam was not solely focused on training medical personnel but was intricately linked to broader vocational education systems. Consequently, this study contributes to a historical understanding of medical education in the late Joseon period. Future studies should explore comparisons with Hyeminseo and Naeuiwon, changes in the social status of the middle class, and Jeonuigam’s role during the transition to modern medical systems.

This study analyzes the career trajectories of students from Jeonuigam in the late nineteenth centry Joseon dynasty, shedding light on its educational functions by focusing on individuals listed in the Jeonhamsaengdoan and Byeoncheonpalsean. The primary subject of this research, the Jeonhamsaengdoan, is a valuable resource for understanding the career paths of Jeonuigam students, containing enrollment information for 384 individuals. The Byeolcheonpalsean, introduced for the first time in this paper, provides information about an alternative method of enrollment known as ‘Byeolcheon’ for students entering Jeonuigam.The analysis of these individuals’ career paths reveals that many Jeonuigam students had overlapping enrollments in other technical institutions, such as Saekwon and Gwangsangam. This suggests that medical education was not limited to specific disciplines but was part of a broader educational framework. Moreover, the Seogyeong system allowed younger siblings to enroll alongside older ones, while the Byeolcheon system, which facilitated recommendations from other institutions, provided educational opportunities for families. These findings highlight the diverse methods in which medical and vocational education were conducted in the late nineteenth century Joseon dynasty.Approximately 66 percent of Jeonuigam students became medical officials, while others pursued careers in fields such as interpreting and various government roles, contributing to society in multiple ways. This study demonstrates that Jeonuigam was not solely focused on training medical personnel but was intricately linked to broader vocational education systems. Consequently, this study contributes to a historical understanding of medical education in the late Joseon period. Future studies should explore comparisons with Hyeminseo and Naeuiwon, changes in the social status of the middle class, and Jeonuigam’s role during the transition to modern medical systems.

This study analyzes the career trajectories of students from Jeonuigam in the late nineteenth centry Joseon dynasty, shedding light on its educational functions by focusing on individuals listed in the Jeonhamsaengdoan and Byeoncheonpalsean. The primary subject of this research, the Jeonhamsaengdoan, is a valuable resource for understanding the career paths of Jeonuigam students, containing enrollment information for 384 individuals. The Byeolcheonpalsean, introduced for the first time in this paper, provides information about an alternative method of enrollment known as ‘Byeolcheon’ for students entering Jeonuigam.The analysis of these individuals’ career paths reveals that many Jeonuigam students had overlapping enrollments in other technical institutions, such as Saekwon and Gwangsangam. This suggests that medical education was not limited to specific disciplines but was part of a broader educational framework. Moreover, the Seogyeong system allowed younger siblings to enroll alongside older ones, while the Byeolcheon system, which facilitated recommendations from other institutions, provided educational opportunities for families. These findings highlight the diverse methods in which medical and vocational education were conducted in the late nineteenth century Joseon dynasty.Approximately 66 percent of Jeonuigam students became medical officials, while others pursued careers in fields such as interpreting and various government roles, contributing to society in multiple ways. This study demonstrates that Jeonuigam was not solely focused on training medical personnel but was intricately linked to broader vocational education systems. Consequently, this study contributes to a historical understanding of medical education in the late Joseon period. Future studies should explore comparisons with Hyeminseo and Naeuiwon, changes in the social status of the middle class, and Jeonuigam’s role during the transition to modern medical systems.

This study analyzes the career trajectories of students from Jeonuigam in the late nineteenth centry Joseon dynasty, shedding light on its educational functions by focusing on individuals listed in the Jeonhamsaengdoan and Byeoncheonpalsean. The primary subject of this research, the Jeonhamsaengdoan, is a valuable resource for understanding the career paths of Jeonuigam students, containing enrollment information for 384 individuals. The Byeolcheonpalsean, introduced for the first time in this paper, provides information about an alternative method of enrollment known as ‘Byeolcheon’ for students entering Jeonuigam.The analysis of these individuals’ career paths reveals that many Jeonuigam students had overlapping enrollments in other technical institutions, such as Saekwon and Gwangsangam. This suggests that medical education was not limited to specific disciplines but was part of a broader educational framework. Moreover, the Seogyeong system allowed younger siblings to enroll alongside older ones, while the Byeolcheon system, which facilitated recommendations from other institutions, provided educational opportunities for families. These findings highlight the diverse methods in which medical and vocational education were conducted in the late nineteenth century Joseon dynasty.Approximately 66 percent of Jeonuigam students became medical officials, while others pursued careers in fields such as interpreting and various government roles, contributing to society in multiple ways. This study demonstrates that Jeonuigam was not solely focused on training medical personnel but was intricately linked to broader vocational education systems. Consequently, this study contributes to a historical understanding of medical education in the late Joseon period. Future studies should explore comparisons with Hyeminseo and Naeuiwon, changes in the social status of the middle class, and Jeonuigam’s role during the transition to modern medical systems.

This study was performed to evaluate the restoration combined with resin infiltration (RI) of early cavitated smooth surface caries lesion in terms of microleakage. Flowable resin and resin-modified glass ionomer cement (RMGIC) were compared. Sound 20 extracted 3rd molars were divided into 2 groups randomly. Artificial decalcified lesion was induced. Cavities were prepared on the mesial and distal surfaces, and randomly set as experimental and control group. RI was applied to the experimental group before cavity restoration. The control group was restored without RI. In group I and II, flowable resin and RMGIC was used for restoration respectively. After thermocycling and silver nitrate immersion, microleakage was assessed by μ-CT. Depth of microleakage was lower in experimental group than control group only in group II (p = 0.05). Microleakage depth was lower in group II than group I in both xperimental and control groups (p = 0.05). RI pretreatment before restoration of early cavitated caries lesions might reduce the microleakage and help long-term maintenance of restoration. In this study, RMGIC was less polymerization shrinkage. Restoration with RMGIC after RI pretreatment reduced the microleakage of the restoration compared to the flowable resin.

We describe a case in which homonymous hemianopsia developed abruptly following an epidural blood patch procedure. The procedure was performed in a patient complaining of post-dural puncture headache after an emergency Cesarean section under spinal anesthesia. Computed tomography and magnetic resonance imaging demonstrated that air bubbles had moved from the prepontine and premedullar cisterns toward the left retrochiasmal region. The homonymous hemianopsia resolved rapidly with conservative management including oxygen, intravenous fluid, and antibiotics. We report on this case with a brief review of the related literature.
Anesthesia, Spinal ; Anti-Bacterial Agents ; Blood Patch, Epidural ; Cesarean Section ; Emergencies ; Female ; Hemianopsia ; Humans ; Magnetic Resonance Imaging ; Oxygen ; Pneumocephalus ; Post-Dural Puncture Headache ; Pregnancy

Background/Aims: Helicobacter pylori (HP) infection is positively associated with metabolic syndrome (MS). However, the long-term effects of eradication therapy on MS and sex differences have not been thoroughly studied. We aimed to investigate the long-term effects of HP eradication on MS and sex differences. Methods: This study included 2,267 subjects who visited a tertiary referral center between May 2003 and May 2019. HP was diagnosed by histology, a Campylobacter-like organism test, and culture, and the subjects were prospectively followed up. The participants were categorized into three groups: HP uninfected, HP infected but non-eradicated, and HP eradicated. The baseline characteristics and changes in metabolic parameters after HP eradication were compared over a 5-year follow-up period. Results: Among 1,521 subjects, there was no difference in baseline metabolic parameters between the HP-uninfected (n=509) and HP-infected (n=1,012) groups, regardless of sex. Analysis of the metabolic parameters during follow-up among HP-uninfected (n=509), HP-non-eradicated (n=346), and HP-eradicated (n=666) groups showed that high-density lipoprotein (HDL) and the body mass index (BMI) increased after eradication, with a significant difference at 1-year of follow-up. In females, HDL increased after eradication (p=0.023), and the BMI increased after eradication in male subjects (p=0.010). After propensity score matching, the HDL change in female remained significant, but the statistical significance of the change in BMI in the male group became marginally significant (p=0.089). Conclusions HP eradication affected metabolic parameters differently depending on sex. HDL significantly increased only in females over time, especially at 1-year of follow-up. In contrast, BMI showed an increasing tendency over time in males, especially at the 1-year follow-up.

Background: We aimed to analyze the risk factors for sudden death after diagnosis of coronavirus disease 2019 (COVID-19) in South Korea and to provide evidence for informing prevention and control interventions for patients at risk of sudden death. Methods: We included 30,302 COVID-19 related deaths registered in the patient management information system (Central Disease Control Headquarters) between January 1, 2021, and December 15, 2022. We collected their epidemiological data recorded by the reporting city, province, or country. We performed multivariate logistic regression analysis to identify risk factors for sudden death after diagnosis of COVID-19. Results: Among the 30,302 deaths, there were 7,258 (24.0%) and 23,044 (76.0%) sudden and non-sudden deaths, respectively. Sudden death means a person who died within 2 days of diagnosis and who did not receive inpatient treatment. Underlying condition, vaccination status, and place of death were significantly associated with the survival period in all age groups. Moreover, region, sex, and prescription were significantly associated with the survival period only in certain age groups. However, reinfection was not significantly associated with the survival period in any age group. Conclusion To our knowledge, this is the first study on the risk factors for sudden death after a diagnosis of COVID-19, which included age, underlying condition, vaccination status, and place of death. Additionally, individuals aged < 60 years without an underlying condition were at high risk for sudden death. However, this group has relatively low interest in health, as can be seen from the high non-vaccination rate (16.1% of the general population vs. 61.6% of the corresponding group). Therefore, there is a possibility for the presence of an uncontrolled underlying disease in this population. In addition, many sudden deaths occurred due to delayed hospital visits to continue economic activities even after the onset of COVID-19 symptoms (7 days overall vs. 10 days average for the group). In conclusion, ‘continued interest in health’ is a key factor in avoiding sudden death in the economically active group (under 60 years of age).

Objectives: This study aimed to classify coronavirus disease 2019 (COVID-19)-related deaths according to whether COVID-19 was listed as the cause of death, and to investigate thedifferences in demographic characteristics and risk factors for COVID-19 death classifications. Methods: A total of 5,625 deaths in South Korea among patients with confirmed COVID-19 from January 20, 2020 to December 31, 2021 were selected. Excluding false reports and unnatural deaths, 5,597 deaths were analyzed. Based on death report data, deaths were classified according to whether the cause of death was listed as COVID-19 (CD) or not (NCD). The epidemiological characteristics and causes of deaths were investigated using descriptive, univariate, and multivariate statistical analyses. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to analyze the risk factors. Results: The case fatality ratio was 0.89% and increased with age. Additionally, 96.4% of the subjects had an underlying disease, and 53.4% died in winter. The proportion of NCDs was 9.3%, of whom 19.1% died at home and 39.0% were confirmed to have COVID-19 after death. Malignant neoplasms (102/416 vs. 637/4,442; OR, 1.71; 95% CI, 1.36−2.16; p < 0.001) were significantly associated with NCD. Conclusion This is the first study to analyze risk factors by cause of death using COVID-19death report data in South Korea. These results are expected to be used as evidence forestablishing a death monitoring system that can collect timely information in a new infectiousdisease pandemic.

Background: To evaluate whether insulin resistance and impaired insulin secretion are useful predictors of incident diabetes in Koreans using nationwide population-representative data to enhance data privacy. Methods: This study analyzed the data of individuals without diabetes aged >40 years from the Korea National Health and Nutrition Examination Survey (KNHANES) 2007–2010 and 2015 and the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS). Owing to privacy concerns, these databases cannot be linked using direct identifiers. Therefore, we generated 10 synthetic datasets, followed by statistical matching with the NHIS-HEALS. Homeostasis model assessment of insulin resistance (HOMA-IR) and homeostasis model assessment of β-cell function (HOMA-β) were used as indicators of insulin resistance and insulin secretory function, respectively, and diabetes onset was captured in NHIS-HEALS. Results: A median of 4,580 (range, 4,463 to 4,761) adults were included in the analyses after statistical matching of 10 synthetic KNHANES and NHIS-HEALS datasets. During a mean follow-up duration of 5.8 years, a median of 4.7% (range, 4.3% to 5.0%) of the participants developed diabetes. Compared to the reference low–HOMA-IR/high–HOMA-β group, the high–HOMA-IR/low– HOMA-β group had the highest risk of diabetes, followed by high–HOMA-IR/high–HOMA-β group and low–HOMA-IR/low– HOMA-β group (median adjusted hazard ratio [ranges]: 3.36 [1.86 to 6.05], 1.81 [1.01 to 3.22], and 1.68 [0.93 to 3.04], respectively). Conclusion Insulin resistance and impaired insulin secretion are robust predictors of diabetes in the Korean population. A retrospective cohort constructed by combining cross-sectional synthetic and longitudinal claims-based cohort data through statistical matching may be a reliable resource for studying the natural history of diabetes.