BACKGROUND/OBJECTIVES: This study is of significant importance as it aims to understand the food consumption practices of those trying to save money on food and the role of health consciousness in food choices. The specific objectives of the current study are 1) to track levels of online community activation over time in 2 online budget food communities, 2) to explore specific ingredients and food groups that are frequently mentioned in budget communities, and finally, 3) to compare the foods and staples of regular budget food and healthy budget food communities. These objectives are crucial in providing a comprehensive understanding of food consumption practices and health consciousness. SUBJECTS/METHODS: The data source for this study was Reddit, and subreddits related to budget foods were targeted for data preparation. After creating a food name dictionary, keyword analysis and topic modeling were conducted to identify key food groups. We compared the regular budget food group to the health-conscious budget food group. RESULTS: The food items commonly mentioned in both groups could serve as key staples for people looking to save money on food preparation. Rice was mentioned the most in both groups. Whereas meat and flour products were more important to the regular budget food group, fruits and vegetables were more valuable to the healthy budget food group. CONCLUSION The results of this research offer insights into the food purchasing behaviors of those attempting to save money and provide practical strategies to make budget foods healthier. This information can be valuable for individuals, policymakers, and health professionals in promoting more nutritious food choices.

BACKGROUND/OBJECTIVES: This study is of significant importance as it aims to understand the food consumption practices of those trying to save money on food and the role of health consciousness in food choices. The specific objectives of the current study are 1) to track levels of online community activation over time in 2 online budget food communities, 2) to explore specific ingredients and food groups that are frequently mentioned in budget communities, and finally, 3) to compare the foods and staples of regular budget food and healthy budget food communities. These objectives are crucial in providing a comprehensive understanding of food consumption practices and health consciousness. SUBJECTS/METHODS: The data source for this study was Reddit, and subreddits related to budget foods were targeted for data preparation. After creating a food name dictionary, keyword analysis and topic modeling were conducted to identify key food groups. We compared the regular budget food group to the health-conscious budget food group. RESULTS: The food items commonly mentioned in both groups could serve as key staples for people looking to save money on food preparation. Rice was mentioned the most in both groups. Whereas meat and flour products were more important to the regular budget food group, fruits and vegetables were more valuable to the healthy budget food group. CONCLUSION The results of this research offer insights into the food purchasing behaviors of those attempting to save money and provide practical strategies to make budget foods healthier. This information can be valuable for individuals, policymakers, and health professionals in promoting more nutritious food choices.

BACKGROUND/OBJECTIVES: This study is of significant importance as it aims to understand the food consumption practices of those trying to save money on food and the role of health consciousness in food choices. The specific objectives of the current study are 1) to track levels of online community activation over time in 2 online budget food communities, 2) to explore specific ingredients and food groups that are frequently mentioned in budget communities, and finally, 3) to compare the foods and staples of regular budget food and healthy budget food communities. These objectives are crucial in providing a comprehensive understanding of food consumption practices and health consciousness. SUBJECTS/METHODS: The data source for this study was Reddit, and subreddits related to budget foods were targeted for data preparation. After creating a food name dictionary, keyword analysis and topic modeling were conducted to identify key food groups. We compared the regular budget food group to the health-conscious budget food group. RESULTS: The food items commonly mentioned in both groups could serve as key staples for people looking to save money on food preparation. Rice was mentioned the most in both groups. Whereas meat and flour products were more important to the regular budget food group, fruits and vegetables were more valuable to the healthy budget food group. CONCLUSION The results of this research offer insights into the food purchasing behaviors of those attempting to save money and provide practical strategies to make budget foods healthier. This information can be valuable for individuals, policymakers, and health professionals in promoting more nutritious food choices.

BACKGROUND/OBJECTIVES: This study is of significant importance as it aims to understand the food consumption practices of those trying to save money on food and the role of health consciousness in food choices. The specific objectives of the current study are 1) to track levels of online community activation over time in 2 online budget food communities, 2) to explore specific ingredients and food groups that are frequently mentioned in budget communities, and finally, 3) to compare the foods and staples of regular budget food and healthy budget food communities. These objectives are crucial in providing a comprehensive understanding of food consumption practices and health consciousness. SUBJECTS/METHODS: The data source for this study was Reddit, and subreddits related to budget foods were targeted for data preparation. After creating a food name dictionary, keyword analysis and topic modeling were conducted to identify key food groups. We compared the regular budget food group to the health-conscious budget food group. RESULTS: The food items commonly mentioned in both groups could serve as key staples for people looking to save money on food preparation. Rice was mentioned the most in both groups. Whereas meat and flour products were more important to the regular budget food group, fruits and vegetables were more valuable to the healthy budget food group. CONCLUSION The results of this research offer insights into the food purchasing behaviors of those attempting to save money and provide practical strategies to make budget foods healthier. This information can be valuable for individuals, policymakers, and health professionals in promoting more nutritious food choices.

BACKGROUND/OBJECTIVES: This study is of significant importance as it aims to understand the food consumption practices of those trying to save money on food and the role of health consciousness in food choices. The specific objectives of the current study are 1) to track levels of online community activation over time in 2 online budget food communities, 2) to explore specific ingredients and food groups that are frequently mentioned in budget communities, and finally, 3) to compare the foods and staples of regular budget food and healthy budget food communities. These objectives are crucial in providing a comprehensive understanding of food consumption practices and health consciousness. SUBJECTS/METHODS: The data source for this study was Reddit, and subreddits related to budget foods were targeted for data preparation. After creating a food name dictionary, keyword analysis and topic modeling were conducted to identify key food groups. We compared the regular budget food group to the health-conscious budget food group. RESULTS: The food items commonly mentioned in both groups could serve as key staples for people looking to save money on food preparation. Rice was mentioned the most in both groups. Whereas meat and flour products were more important to the regular budget food group, fruits and vegetables were more valuable to the healthy budget food group. CONCLUSION The results of this research offer insights into the food purchasing behaviors of those attempting to save money and provide practical strategies to make budget foods healthier. This information can be valuable for individuals, policymakers, and health professionals in promoting more nutritious food choices.

BACKGROUND: Enteroviruses are known as major pathogen for aseptic meningitis. Although rapid diagnosis for enteroviruses is very essential to exclude bacterial infections in patients with meningitis, classical diagnostic method based on virus isolation is not practicable for timely treatment of patients due to its laborious and time-consuming procedure. Recently molecular methodologies as alternatives are routinely used for rapid and sensitive diagnosis for enteroviruses infections. METHODS: Reverse transcription (RT)-PCR ELISA kit for targeting 5'non-coding region (NCR) with highly conserved genetic identity among all genotypes of enteroviruses was introduced in this investigation. RT-PCR ELISA was evaluated about sensitivity and specificity through virus isolation using clinical specimens from patients suspected of enteroviral infections and enteroviral isolates comparing with conventional RT-PCR identifying them. RESULTS: The detection limit of the RT-PCR ELISA was up to 10-100 folds higher than virus isolation using cell culture and conventional RT-PCR. On comparison between above two methods, the detection rate of RT-PCR ELISA for clinical specimens from patients with aseptic meningitis was 7% higher than that of conventional RT-PCR targeting 5'NCR (P=0.016). CONCLUSIONS: Our results suggest that RT-PCR ELISA developed in this study could be an alternative diagnostic method for the detection of enteroviral genome with high sensitivity and specificity.
5' Untranslated Regions ; Adolescent ; Child ; Child, Preschool ; Enterovirus/genetics/*isolation & purification ; Enterovirus Infections/*diagnosis ; *Enzyme-Linked Immunosorbent Assay ; Humans ; Infant ; Meningitis, Aseptic/diagnosis ; RNA, Viral/analysis ; *Reverse Transcriptase Polymerase Chain Reaction ; Rotavirus/genetics ; Rotavirus Infections/diagnosis ; Sensitivity and Specificity

BACKGROUND: Emergencies in dentistry can be classified as medical and dental. Medical emergencies occur mainly during dental treatment in patients with a systemic disease. Dental emergency departments are largely divided into dental emergency rooms located in dental college hospitals and medical emergency rooms located in medical institutions. This study aimed to analyze the characteristics of and provide help to dental emergency patients in a dental hospital. METHODS: Overall, 1806 patients admitted to a dental emergency room at Yonsei University Dental Hospital for 1 year were included. The data collection period was from October 1, 2014 to September 30, 2015. An investigator reviewed medical records from the electronic medical record (EMR) system and radiographs. RESULTS: The patients were 1,070 men and 736 women. The sex ratio was 1.45:1. The commonest age group was of 0–9 years, including 451 (25.0%) patients, followed by 20–29 years, including 353 (19.5%) patients, and 30–39 years, including 277 (15.3%) patients. Of the 108 patients transferred to the Severance emergency department, 81 had trauma, 19 were in pain, 4 were bleeding, and 4 had other complaints. Among chief complaints, 1,079 patients (60.3%) had trauma, 564 (31.5%) had pain, and 75 (4.2%) had bleeding. Twenty-three cases (1.3%) were caused by temporomandibular disorder (TMD). CONCLUSION: Dentists should be able to adequately assess patients in a dental emergency room and treat trauma, pain, and bleeding.
Data Collection ; Dentistry ; Dentists ; Electronic Health Records ; Emergencies ; Emergency Service, Hospital ; Female ; Hemorrhage ; Humans ; Male ; Medical Records ; Research Personnel ; Retrospective Studies ; Sex Ratio ; Temporomandibular Joint Disorders

Echovirus 6 (ECV6) is the prevalent serotype detected in aseptic meningitis cases in Korea. To analyze the genetic variation of ECV6 isolates recently circulating in Korea, we determined the partial sequence of the VP1 capsid gene from 22 Korean ECV6 isolates and performed pairwise analysis against 42 reference strains from the GenBank database using MegAlign. The 22 Korean ECV6 isolates formed 3 distinct genetic clusters: Kor-lineage I, II, and III. The Korean ECV6 strains showed significant genetic diversity with 14.8~22.8% nucleotide divergence among the 3 different lineages. These ECV6 Kor-lineages were demonstrated to belong to different genetic clusters using VP1 sequence-based phylogenetic analysis, implying that the recently circulating Korean ECV6 strains have potential antigenic variation.
Antigenic Variation ; Capsid ; Databases, Nucleic Acid ; Echovirus 6, Human ; Enterovirus B, Human ; Genetic Variation ; Korea ; Meningitis, Aseptic

PURPOSE: To clarify the difference between the bolus-tracking technique and a fixed scan delay protocol in the achievement of the optimal pancreatic phase of the pancreas with MDCT. MATERIALS AND METHODS: 526 patients underwent pancreatic and portal venous phase imaging of the pancreas using 16-channel MDCT. All the examinations were randomized into either scanning using a bolus-tracking technique with a scan delay of 20s after the aorta was enhanced > 100 HU (groups 1 and 2) or scanning with a scan delay of 38 s from the beginning of the injection (groups 3 and 4). A contrast material of 300 mgI/mL (groups 1 and 3) or 370 mgI/mL (groups 2 and 4) at an injection speed of 3 mL/sec was injected at 2 mL/kg body weight. The pancreatic CT attenuation values were compared. RESULTS: The scan delay times of the pancreatic phase in groups 1 and 2 were 38+/-3.8s and 37.4+/-3.4s, respectively. At the pancreatic phase, the pancreatic attenuation values of groups 1 and 2 were slightly higher than those of groups 3 and 4 (115.5+/-15.4 vs 111.7+/-15.1HU; p=0.093, 128.3+/-17.1 vs 119+/-17.1HU; p=0.003). There was no significant difference between groups at the portal venous phase. CONCLUSION: The use of a bolus-tracking technique in the optimal pancreatic phase of pancreatic CT does not significantly improve the pancreatic enhancement but does at higher iodine concentrations.
Aorta ; Body Weight ; Humans ; Iodine ; Pancreas*

PURPOSE: We sought to maximize the antitumor effect of an anticancer vaccine based on genetically modified endothelial cells by combining it with the platelet-derived growth factor receptor inhibitor imatinib. MATERIALS AND METHODS: Human umbilical vein endothelial cells (HUVECs) were infected with 10 MOI of Ad-CMV-mGMCSF to make anticancer vaccines. One million mouse bladder cancer cells (MBT-2) were subcutaneously inoculated in C3H mice. The experimental groups included the following: Group 1 (phosphate-buffered saline), Group 2 (anticancer vaccine and GM-CSF), Group 3 (imatinib), and Group 4 (anticancer vaccine, GM-CSF, and imatinib). Tumor growth and body weight were measured weekly. At 4 weeks, the tumors were immunostained with anti-CD31, and microvessel density (MVD) was measured. To evaluate the immunological mechanism of each treatment, flow cytometry analysis of activated CD4 and CD8 cells was performed. RESULTS: At 4 weeks, the mean body weight of each group, excluding the extracted tumor weight, was not significantly different. Since week 3, the mean tumor volume in Group 4 was the smallest among the treatment groups (p<0.05), and a synergistic suppressive effect on tumor volume was observed in Group 4. The MVD in Group 4 was the most suppressed among the treatment groups (p<0.05), and a synergistic anti-angiogenic effect was observed. Flow cytometry analysis revealed that activated CD4+ and CD8+ cells increased in Group 2 and decreased in Group 3 compared with the other groups. CONCLUSIONS: The combination of genetically modified endothelial cell vaccines and imatinib showed a synergistic antiangiogenic effect in bladder cancer.
Animals ; Benzamides ; Body Weight ; Endothelial Cells ; Flow Cytometry ; Granulocyte-Macrophage Colony-Stimulating Factor ; Human Umbilical Vein Endothelial Cells ; Immunotherapy ; Mice ; Mice, Inbred C3H ; Microvessels ; Piperazines ; Platelet-Derived Growth Factor ; Pyrimidines ; Receptors, Platelet-Derived Growth Factor ; Tumor Burden ; Urinary Bladder ; Urinary Bladder Neoplasms ; Vaccines ; Imatinib Mesylate