No abstract available.

BACKGROUND: The umbilicus is a simple scar that obliterates the portal through which the omphalomesenteric duct connected the primitive gut to the yolk sac; through which the intestine was expelled prior to its rotation; through which passed the umbilical arteries and vein; at which the allantosis attached to the early urinary bladder; and at which the umbilical cord that carried these structures was fused to the body wall. The umbilicus is situated at the level of L3 to L4 in the midline of the abdomen. It's shape, size, and configuration vary greatly related to age and sex. Deramtoses of the umbilicus are umbilical hernia, congenital abnormalities, granulomas, omphalith, infections, eczema and tumors. OBJECTIVE: The purpose of this study was to examine the umbilical shape and size related to age and sex and diseases of the umbilicus. METHODS: During a 6-month-period from May to October, 1998, 420 person's umbilical shapes and size were examined with regard to age and sex. The diseases of the umbilicus were evaluated, too. RESULTS & CONCLUSIONS: 1. The mean vertical diameter of the umbilicus is 1.89+/-0.65cm and the mean transverse diameter is 1.98+/-0.86cm. The mean diameter of umbilicus in women(vertical: 1.98+/-0.73cm, transverse: 2.07+/-0.99cm) is larger than the mean diameter of umbilicus in men(vertical: 1.80+-0.53cm, transverse: 1.89+/-0.66cm)(p<0.05). 2. The vertical diameter of umbilicus in both sexes showed increasing aspect until the 30-39 year old group, and the transverse diameter of umbilicus in both sexes showed increasing aspect until the 40-49 year old group. 3. The shapes of umbilicus were divided into the protruded type and the depressed type. Most of our cases showed the depressed type. The protruded types were more in the 0-9 year old group(23%) than other year old groups. The shapes of umbilicus were divided into the round type and the elliptical type, too. The elliptical type(transverse diameter>vertical diameter) is more than the elliptical type(vertical diameter>transverse diameter) in men, and the elliptical type(vertical diameter>transverse diameter) is more than the elliptical type(transverse diameter>vertical diameter) in women. 4. The diseases of the umbilicus are allergic contact dermatitis(6 cases), pityriasis rosea(5 cases), psoriasis(3 cases), scabies(3 cases), rhus dermatitis(2 cases), pemphigus(2 cases), drug eruption(1 case), and insect bite(1 case).
Abdomen ; Cicatrix ; Congenital Abnormalities ; Eczema ; Female ; Gastrula ; Granuloma ; Hernia, Umbilical ; Humans ; Insects ; Intestines ; Male ; Pityriasis ; Rhus ; Umbilical Arteries ; Umbilical Cord ; Umbilicus ; Urinary Bladder ; Veins ; Vitelline Duct ; Yolk Sac

Malaria infection is not uncommon in Korea these days, but there was no report of malaria infection in the patients who had been transplanted his or her kidney. With the immunosuppression, the atypical findings are frequent and make prompt diagnosis difficult. We report a case of malaria which showed atypical clinical course but treated successfully with conventional anti-malarial drug therapy. A 37 year old male patient were transplanted his kidney in Sep. 1997. He was admitted because of fever, which lasted 40 - 50 min every afternoon for 27 days. Numerous trophozoites were found on his peripheral blood smear, which was diagnosed as vivax malaria. Chloroquine and primaquine were given, and fever subsided next day. The patients has been stayed afebrile thereafter. We reported a case of malaria in the renal transplanted patient with the review of literatures.
Adult ; Chloroquine ; Diagnosis ; Drug Therapy ; Fever ; Humans ; Immunosuppression* ; Kidney Transplantation ; Kidney* ; Korea ; Malaria* ; Malaria, Vivax ; Male ; Plasmodium vivax ; Primaquine ; Trophozoites

PURPOSE: To compare postoperative wavefront aberration and visual functions between aspherical Tecnis Z9003, a new acrylic aspheric intraocular lens (IOL), and spherical AcrySof SA60AT IOL. METHODS: Fifty patients (56 eyes) who underwent cataract extraction and were implanted with spherical or aspherical IOLs were randomly evaluated by wavefront analysis, including an examination of spherical aberration and higher-order aberrations using two different types of aberrometers (ray tracing and automatic retinoscope), manifested refraction, a contrast sensitivity test, and modulation transfer function (MTF), three months after surgery. RESULT: There were no statistically significant differences of spherical equivalent and best-corrected visual acuity between the two different IOL groups. However, the aspherical IOL group showed less spherical aberration and better contrast sensitivity and MTF than the spherical IOL group. CONCLUSIONS: Tecnis Z9003 could compensate for positive spherical aberrations of the cornea and improve contrast sensitivity and MTF, thereby improving visual function.
Cataract Extraction ; Contrast Sensitivity ; Cornea ; Humans ; Lenses, Intraocular ; Visual Acuity

PURPOSE: To compare the anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA) and refractive change after cataract surgery between 3-piece and 1-piece aspheric intraocular lens (IOL) implantation. METHODS: The present study consisted of 16 patients (25 eyes) having 3-piece aspheric Tecnis(R) ZA9003 IOL and 21 patients (30 eyes) having 1-piece aspheric Tecnis(R) ZCB00 IOL. The ACD, ACV, and ACA were measured using an anterior eye segment analysis system (Pentacam, Oculus, Wetzlar, Germany) preoperatively and postoperatively 1 week and 1 month. Refractive outcomes were evaluated using an autokeratometer. RESULTS: When comparing the 3-piece (Tecnis(R) ZA9003) and 1-piece (Tecnis(R) ZCB00) IOL with the same optic, ACD, ACV, and AVA increased significantly after cataract surgery. The 1-piece IOL showed deeper ACD than the 3-piece IOL at postoperative 1 week and 1 month. Postoperative refraction showed slight myopic shift compared with target diopter, but was stable in both groups. CONCLUSIONS: There was significant increase in ACD, ACV, and ACA after cataract surgery in both IOL-inserted groups. Results showed stable refraction after cataract surgery in both groups. Consideration of the A-constant will be needed because of myopic change with the 1-piece IOL.
Anterior Chamber ; Anterior Eye Segment ; Cataract ; Humans ; Lenses, Intraocular

PURPOSE: To compare the anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA) and refractive change after cataract surgery between 3-piece and 1-piece aspheric intraocular lens (IOL) implantation. METHODS: The present study consisted of 16 patients (25 eyes) having 3-piece aspheric Tecnis(R) ZA9003 IOL and 21 patients (30 eyes) having 1-piece aspheric Tecnis(R) ZCB00 IOL. The ACD, ACV, and ACA were measured using an anterior eye segment analysis system (Pentacam, Oculus, Wetzlar, Germany) preoperatively and postoperatively 1 week and 1 month. Refractive outcomes were evaluated using an autokeratometer. RESULTS: When comparing the 3-piece (Tecnis(R) ZA9003) and 1-piece (Tecnis(R) ZCB00) IOL with the same optic, ACD, ACV, and AVA increased significantly after cataract surgery. The 1-piece IOL showed deeper ACD than the 3-piece IOL at postoperative 1 week and 1 month. Postoperative refraction showed slight myopic shift compared with target diopter, but was stable in both groups. CONCLUSIONS: There was significant increase in ACD, ACV, and ACA after cataract surgery in both IOL-inserted groups. Results showed stable refraction after cataract surgery in both groups. Consideration of the A-constant will be needed because of myopic change with the 1-piece IOL.
Anterior Chamber ; Anterior Eye Segment ; Cataract ; Humans ; Lenses, Intraocular

No abstract available.
Diplopia ; Humans ; Isaacs Syndrome ; Neoplasm Metastasis ; Orbit

BACKGROUND: Coronary angiography have become important and integral components in the investigation of patients with cardiovascular disease. Technical improvement combined with an increased need of coronary angiography, and efforts to decrease the length of inpatient hospital stay have prompted the development of outpatient coronary angiography. In this study, we compared the procedure-related complications and costs of inpatient and outpatient coronary angiography when performed at the same institution. In addition, we attempted the coronary angiography as outpatient setting in patients with unstable angina, old age, and anticoagulation therapy, who have been regarded as contraindication for outpatient procedure. METHODS: Diagnostic coronary angiography was performed in 199 cases as inpatient setting, and 225 cases as outpatient setting at Korea University Guro Hospital From January through July 1996. There was no significant difference in sex, age, risk factor, blood pressure, cholesterol level, and ejection fraction. We did not give the heparin during the procedure and, use the Judkins' method in all patients. After the procedure, pressure dressing was done with compressor device for 15 minutes, then sandbag was applied on the puncture site. In outpatient, they took bed rest for 6 hours in one-day care room. RESULTS: 1) In the inpatient group, there were 6 cases(3.0%) of catheterization-related complication, and there were 7 cases(3.1%) of complication in the outpatient group. There was no major complication in both groups, such as death, myocardial infarction, stroke, and perforation of heart and great vessels. In the inpatient group, 2 cases of arrhythmia, 3 cases of hematoma at puncture site, and 1 case of femoral artery pseudoaneuryrsm occurred. In the outpatient group, 2 cases of arrhythmia, 1 case of hematoma at puncture site, 2 cases of skin rash, 1 case of acute febrile reaction, and 1 case of femoral artery dissecting aneurysm developed. There was no significant difference in the rate of complications between two groups(p=0.947). 2) In the outpatient group, there were 28 cases of unstable angina, 6 cases of old age more than 75 years, and 5 cases of anticoagulant has been taken. No catheterization-related complication occurred in those groups. 3) The costs and duration of hospital stay in the inpatient group were won480,230+/-86,800 and 50.3+/-12.3 hours and those in the outpatient group were won276,870+/-32,050 and 8.3+/-1.2 hours. There was significant difference between two groups in the costs and duration of hospital stay(p<0.01, p<0.01). CONCLUSIONS: Outpatient coronary angiography could be done safely with low complication rate, and could reduce the costs and hospital stay. For high risk group such as unstable angina, old age, and anticoagulation therapy, there was no complication in this study, but more experiences and available data should be accumulated to be accepted as a general guideline.
Aneurysm, Dissecting ; Angina, Unstable ; Arrhythmias, Cardiac ; Bandages ; Bed Rest ; Blood Pressure ; Cardiovascular Diseases ; Cholesterol ; Coronary Angiography* ; Exanthema ; Femoral Artery ; Heart ; Hematoma ; Heparin ; Humans ; Inpatients ; Korea ; Length of Stay ; Myocardial Infarction ; Outpatients* ; Punctures ; Risk Factors ; Stroke

PURPOSE: Lymph-node metastasis is one of the most important prognostic factors in gastric cancer. However, it can be missed with conventional histologic examination with hematoxylin-eosin staining. Several methods have been introduced to improve the detection rate of micrometastasis. Among them, immunohistochemical staining with the anti-cytokeratin antibody is known to be an easy and useful method. METHODS: We used immunohistochemical staining with the anti-cytokeratin antibody to evaluate the incidence of micrometastasis in 48 patients with advanced gastric cancer who had been diagnosed as lymph-node negative by H&E, and its relationship to various clinicopathologic factors. RESULTS: Lymph-node micrometastasis (anti-cytokeratin antibody positive) was found in 15 (31.3%) of the 48 patients and in 33 (1.75%) of 1884 lymph nodes. Among the clinicopathologic variables, only lymphatic invasion was significantly associated with micrometastasis status. The gender, the age, the tumor size, the location of the tumor, the histologic type, and the depth of invasion were not significantly associated with micrometastasis status. During the average follow-up period of 21 months, 6 patients suffered a recurrence, and 2 of these patients died of the cancer recurrence. The recurrence and mortality rates were not significantly associated with micrometastasis status. CONCLUSION: Micrometastasis in stomach cancer was frequent when the primary tumor had invaded the lymphatic vessels.
Follow-Up Studies ; Humans ; Incidence ; Keratins ; Lymph Nodes* ; Lymphatic Vessels ; Mortality ; Neoplasm Metastasis ; Neoplasm Micrometastasis* ; Recurrence ; Stomach Neoplasms*

BACKGROUND: It has been well known that the bone and kidney are the principle organs of parathyroid hormine (PTH) actions. Although patients with primary hyperparathyroidism show a high incidence of LVH and trophic effects of PTH on adult rat ventricular cardiomyocytes were investigated in vitro, effect of PTH on the cardiac tissue in vivo is unknown. METHODS: We examined the effects of PTH on the cardiomyocyte and interstitial tissue using adult rat heart. Twenty-two female Sprague-Dawley rats were ovariectomized bilaterally at three months old and weighing in 250 - 300 gm in order to exclude the trophic effect of estrogen. We administrated human parathyroid hormone (20 ug subcutaneously 5 times per week) to 12 rats for 4 weeks after raising for 8 weeks (PTH group):the remaining 10 rats received only normal saline (control). We measured left ventricular thickness [IVS+LVPW)/2] and number of cardiomyocytes and interstitial fibrosis on LM (H & E and Masson's trochrome stain) and EM. RESULTS: 1) LV wall thickeness tended to increase in PTH group as compared with control (2.16+/-0.31 vs 1.12+/-0.21 mm, p=0.099). 2) The number of cardiomyocyte in PTH group was significantly less than that of control (61.2+/-13.1 vs 70.5+/-14.9, p=0.003, Magnification x 400). 3) There was no significant change of interstitial fibrosis between PTH group and control. CONCLUSION: These results shggest that PTH may produce left ventricular hypertrophic effects in aged ovariectomized rat that resulted form hypertrophy of cardiomyocyte without increase of interstitial connetive tissue.
Adult ; Animals ; Estrogens ; Female ; Fibrosis ; Heart ; Humans ; Hyperparathyroidism, Primary ; Hypertrophy ; Hypertrophy, Left Ventricular* ; Incidence ; Kidney ; Myocytes, Cardiac ; Ovariectomy ; Parathyroid Hormone* ; Rats* ; Rats, Sprague-Dawley