This erratum is being published to correct the company errors.
Adult ; Drinking ; Humans ; Hypertension ; Obesity, Abdominal

Necleolar organizer regions(NORs) ARE LOOPS OF DNA which transcribe to ribosomal RNA by RNA polymerase I. Since NOR-associated proteins are argyrophilic, silver staining method has been used for demonstration of AgNORs. The numbers and/or configurations of NORs may reflect the activities of cells in hyperplastic and neoplastic conditions. To evaluated the applicability of AgNORs in the diagnosis of hepatocellular carcinoma, the author had performed silver staining on the routinely processed, formalin-fixed, paraffin-embedded sections of 14 cases of normal liver(control), 23 cirrhotic liver, and 21 hepatocellular carcinoma. The results are summarized as follows: 1) The mean number of AgNORs per nucleus(mAgNOR) of normal liver, cirrhotic liver and hepatocellular carcinoma was 1.45+/-0.07, 2.53+/-0.38 and 5.52+/-1.63, respectively. The difference of mAgNOR between normal and cirrhotic liver, and between cirrhotic liver and hepatocellular carcinoma was statistically significant, respectively(p<0.01). 2) The percentage of nuclei showing five or more AgNORs per nucleus(pAgNOR) was 0.07% in normal liver, 7.59% in cirrhotic liver, and 60.49% in hepatocellular carcinoma. 3) AgNORs in hepatocellular carcinoma were large, pleomorphic and irregularly clumped, in addition to increase of mAgNOR and high pAgNOR. In conclusion, the increase of mAgNOR, high pAgNOR and large, irregular AgNORs are regarded as an additional helpful finding for the histopathological diagnosis of hepatocellular carcinoma.
Carcinoma, Hepatocellular

Peutz-Jeghers polyp with pseudoinvasion is characterized by the presence of mucosal islands within muscle layer often associated with mucinous cysts. It occurs when mucosal components completely penetrate the muscularis propria, and shows no cytologic signs of malignancy. In most instances, the lesion may be the result of forces exerted during intussusception in the involved small intestine. We describe a case of Peutz-Jeghers polyposis with pseudoinvasion in a 24-year-old female patient. This patient presented with intussusception and a segmental resection of the ileum was performed. Microscopically, it disclosed a hamartomatous polyp with pseudoinvasion. There were glandular islands and mucinous cysts embedded within the bundle of muscle, layer, extending, to the subserosa. There was o evidence of cellular dysplasia or desmoplasia.
Female ; Humans ; Cysts

Total 481 cases of gallstones from Korean patients operated at Keimyung University Dongsan Hospital during the last 6 years were classified by macroscopic view according to the classification of Sato, et al and reviewed with a special reference to age, sex, and kinds and sites of gallstones. Gallstrones were present predominatly in the age of 50-60 years, the average 52. Sex ratio (M:F) was nearly equal, being 1:1.05. Gallbladder was the most frequent site, comprising 53.2%, followed by common bile duct, 23.3% and intrahepatic location, 3.7%. Macroscopic classification revealed pigment gallstones in 53.0% (calcium bilirubinate, 41.8%; black, 11.2%); cholesterol gallstones in 36.2%, of which mixed stone being 33.1%. Cholesterol gallstones occurred predominantly in 50-60 years of age with a prediletion to females. On the contrary, elderly persons more than 60 years of age had calciu bilirubinate stones. No sex difference was found in the calcium bilirubinate stones. Eightly-six percent of cholesterol gallstones were present in the gallbladder only. Common bile duct stones were mostly composed of pigment gallstones in 80.4%.
Female ; Humans

Two unusual and rare forms of Brenner tumor are reported and the literatures are reviewed. The one, "proliferating" Brenner tumor, morphologically resembling low grade papillary transitional cell carcinoma of urinary bladder and regarded as a third variant intermediate between the benign and malignant forms; the other, malignant Brenner tumor of right ovary, corresponding to grade III transitional cell carcinoma of urinarybladder with areas of invasive squamous cell carcinoma and benign Brenner tumor of left ovary, combined with bilateral cystic teratomas. These tumors give additional support to the concept that Brenner tumors are composted of epithelium of urinary tract(urothelial) type.

No abstract available.
Stomach Neoplasms* ; Weight Loss*

This study was done to identify the effectiveness of a proper positioning on musculoskeletal complication on patient with Stroke by using a quasi-experimental study. A total of 18 patients were selected as a subject from June 1st to October 31th 1998 who had been hospitalized at Intensive Care Units in K medical center. A experimental group consists of 8 patients who were given proper positioning every two hours. A control group consists of 10 patients who were given traditional positioning. The collected data were analyzed by SPSS windows including chi-test(Fisher's exact method), Wilcoxon Rank Sum test and McNemar test. The result of this study was summerized as follows: 1) The experimental group with proper positioning has shown lower shoulder pain score, dorsiflexion contracture score, Shoulder subluxation score and higher Range of Motion and than the control group. 2) The experimental group with proper positioning has shown lower muscle pain score and edema score than the control group, but it was not statistically significant. Therefore, proper positioning could be applied as an independent nursing intervention for patients on Stroke in order to facilitate rehabilitation.
Contracture ; Edema ; Humans ; Intensive Care Units ; Myalgia ; Nursing ; Range of Motion, Articular ; Rehabilitation ; Shoulder ; Shoulder Pain ; Stroke*

This study was done to investigate some selected epidemiological characteristics of accidents occured in the closed-ward of a psychiatric hospital in Seoul during one year period from Jan. 1, 1993 toDec. 31, 1993. For this study, 1,570 accidents(702 patients) reported from 1,833 discharged patients were analysed. Major findings obtained from this study were as follows; 1. Prevalence rate of the accidents were 38 persons per 100 discharged pateints and 86 accident spells per 100 discharged patients. 2. The highest risk of accident was noticed in the group of male, 20-29 age, middle school graduate, and divorced. 3. By diagnostic category, accident rates per 100 discharged patients were 339 spells in seizure disor-der, 102 in substance abuse, 93 in schizophrenia, 69 in alcoholism, and 61 in mood disorder. 4. By the period, the accident rate was higher within I month after admission, and the rate was higher in April and November, Wednesday, the day of family visiting, and during day time. 5. Accident types were violent behavior(53%), alcohol drinking(12%), emergency for physical episode(9%), elopement(7%), property damage (5%), self-inflicted injury and suicidal attempt (4%). Severity of damage was usually minimal, and the persons who were commonly involved in the accidents were the petients rather than him self and therapist.
Alcoholism ; Divorce ; Emergencies ; Epidemiologic Studies* ; Hospitals, Psychiatric* ; Humans ; Male ; Mood Disorders ; Prevalence ; Schizophrenia ; Seizures ; Seoul ; Substance-Related Disorders

PURPOSE: This study was to examine the relationship of knowledge, health beliefs, and prevention behaviors of osteoporotic fracture in outpatients with osteoporosis. METHODS: The subjects were 120 outpatients receiving osteoporosis treatment on K hospital in G city from Dec. 2007 to Feb. 2008. Questionnaires were collected and analyzed using the SPSS/WIN 12.0 program for descriptive statistics, and t-test, ANOVA, and Pearson correlation coefficient. RESULTS: Subjects were treated for fracture about 28 months. The mean score of knowledge, health belief and prevention behaviors in subjects were 17.5 +/- 3.22, 2.8 +/- 0.23 and 2.8 +/- 0.38 respectively. The score of health belief recorded the lowest point. However, the score of knowledge varied with general and disease-related characteristics of subjects. In contrast, the score of prevention behaviors did not showed any significant differences. Fracture prevention behavior in subjects showed rather higher relationship with the health belief system than the knowledge of fracture prevention. CONCLUSION: The present work suggested that education program for prevention behaviors of fracture should be developed to focus on altering the health belief system rather than the knowledge of osteoporotic fracture prevention. Furthermore, individual education program based on living circumstances and daily life habits should be also developed.
Humans ; Osteoporosis ; Osteoporotic Fractures ; Outpatients ; Surveys and Questionnaires

BACKGROUND: The verse transcriptase polymerase chain reaction (RT-PCR) has been widely used to analyze the bcr/abl fusion mRNA in chronic myelogenous leukemia (CML). Fresh or cryopreserved cells may not always be available for molecular diagnosis. So we investigated the value of stored bone marrow aspirate smears as the sources of material for the detection of bcr/abl mRNA. METHODS: We extracted RNA using modified Chomczynski method, and amplified bcr/abl mRNA by RT-PCR from the 70 cases of bone marrow smear slides stored from 7 days to 7 years, which were comprised of 49 CML, 11 other chronic myeloproliferative disorders (CMPD) and 10 acute lymphoblastic leukemia (ALL). Sensitivity of RT-PGR was tested using the slide smears prepared with 10(0)-10(6) K562 cells, and RT-PCR results losing each fresh bone marrow cellular suspension and slide smears in 24 patients were compacted. For major bcr/abl rearrangement, RT-PCR was performed by nested PGR afters GDNA synthesis losing downward primer and beta2-microglobulin was used as RNA controls. RESULTS: The sensitivity of RT-PCR for detecting bcr/abl mRNA was l02 cells per slide. Sixty one cases (86%) of 70 bone marrow aspirate smears showed positive results of beta2-micyoglobulin cDNA as an indicator of intact RNA. Thirty nine cases of 42 beta2-microglobulin cDNA positive CML bone marrow aspirate smears showed 29 b3a2 type mRNA and 10 b2a2 type mRNA. Nine cases of 11 bone marrow aspirate smear with other CMPD showed negative results of bcr/abl mRNA. Two cases of 10 ALL bone mallow aspirate smears had b2a2 type mRNA and b3a2 type mRNA, respectively. The results for detection of bcr/abl mRNA with fresh cell suspensions of 24 patients were same as the bone marrow aspirate smears storied for 7 days to 1 year. CONCLUSIONS: These data indicated that RNA obtained from bone marrow smears storied for less than 1 year was valuable as the source of RT-PGR for the detection of bcr/abl mRNA in CML and the bone marrow smears stored for much longer period ould be assailable as the specimens for retrospective analysis of specific gene alter-ation in other hematologic malignancy.
Bone Marrow* ; Diagnosis ; DNA, Complementary ; DNA-Directed RNA Polymerases ; Hematologic Neoplasms ; Humans ; K562 Cells ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; Myeloproliferative Disorders ; Polymerase Chain Reaction ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction* ; RNA ; RNA, Messenger* ; RNA-Directed DNA Polymerase* ; Suspensions