Clinical observation was performed on 81 cases who were received exchange transfusion at Ilsin Christian Hospital from January, 1986 to Decrmber, 1990. The results obtained were as follows: 1) Among 6,388 cases of neonatal jaundice, the exchange transfusion was performed on 81 cases (1.27%). 2) There was no sex predominance (male 40, female 41). The birth weight of 75 cases(92.6%) ranged from 2,500 gm 4,000 gm. 3) The most predominant delivery type was normal vaginal delivery (66 cases, 81.5%). Instrumental delivery was 9 cases (11.1%) that was higher than control group (4.2%). 4) Analysing the exchanged 81 cases, sepsis accounted for 28 cases (34.6%) of the total exchanged group:ABO incompatibility 25 cases (30.9%), complicated causes 13 cases(16.0%), unknown causes 12 cases (14.8%) and Rh incompatibility 1 cases (1.2%). 5) Repeated exchange transfusion was required in 12 cases (16.0%). 6) In 20 cases (24.7%), exchange transfusion was performed on 7 days or more after birth. In 4 cases (4.9%), including 1 cases of Rh incompatibility, exchange transfusion was done within 24 hours after birth. 7) The most common organism of sepsis, which was the most predominant etiology of exchange transfusion was E. coli in 12 cases (31.5%). 8) After exchange transfusion, serum bilirubin, Hb and reticulocyte count were decreased by 24%, 22% and 36%, respectively.
Bilirubin ; Birth Weight ; Female ; Humans ; Infant, Newborn ; Jaundice, Neonatal ; Parturition ; Reticulocyte Count ; Sepsis

Purpose: The study is examined the effects of the smoking cessation program of life skills training using flipped learning for male middle school students. Methods: The study was a nonequivalent control group non-synchronized design. The Smoking Cessation Program of life skills training using flipped learning is a Smoking Cessation Program that applied 5 stages of flipped learning such as before class, introductory class, during class, after class, and during work. Participants were 32 male students attending a middle school in D city, with 16 in the control group and 16 in the experiment group. Data collection was conducted from February 26, 2019 to May 14, 2019 for the control group, and from May 28, 2019 to August 19, 2019 for the experiment group. The collected smoking knowledge, smoking attitude, self-efficacy, basic psychological needs, and urine cotinine were analyzed by x2 test, independent t-test, two-way repeated measured ANOVA, and Fishers exact test using the SPSS 25.0 program. Results: The experimental group showed higher smoking knowledge, smoking attitude, self-efficacy, basic psychological need, and urine cotinine negative response than the control group, and there were significant differences. Conclusion These findings indicate that the Smoking Cessation Program of life skill training using flipped learning is an effective intervention for cessation of middle school male students, and it has a positive effect on the increase in urine cotinine, and a physiological indicator of the cessation effect, and is effective in the success of smoking cessation.

Herpes simplex esophagitis can occur in those with normal immune function, but is more often seen in those who are immunocompromised. In one series, 5 percent of post-kidney transplant recipients had herpes esophagitis. We experienced a case of herpes simplex esophagitis, following renal transplantation in a 9 year old male. He complained of epigastric pain, nausea and blood-tinged vomiting. Endoscopic examination showed volcano ulcer, mucosal friability and multiple confluent ulcers covered by whitish exudates on elevated margin in the middle and lower esophagus. Microscopic findings revealed multinucleated giant cells, margination of chromatin, intense nonspecific inflammation and strong positive for herpes simplex virus immunohistochemical staining. Esophageal lesions and symptoms improved after acyclovir therapy.
Acyclovir ; Child* ; Chromatin ; Esophagitis ; Esophagus ; Exudates and Transudates ; Giant Cells ; Herpes Simplex* ; Humans ; Inflammation ; Kidney Transplantation ; Male ; Nausea ; Simplexvirus* ; Transplantation ; Ulcer ; Vomiting

BACKGROUND: This study aimed to investigate bradycardia as an adverse effect after administration of dexmedetomidine during 33degrees C target temperature management. METHODS: A retrospective study was conducted on patients who underwent 33degrees C target temperature management in the emergency department during a 49-month study period. We collected data including age, sex, weight, diagnosis, bradycardia occurrence, target temperature management duration, sedative drug, and several clinical and laboratory results. We conducted logistic regression for an analysis of factors associated with bradycardia. RESULTS: A total of 68 patients were selected. Among them, 39 (57.4%) showed bradycardia, and 56 (82.4%) were treated with dexmedetomidine. The odds ratio for bradycardia in the carbon monoxide poisoning group compared to the cardiac arrest group and in patients with higher body weight were 7.448 (95% confidence interval [CI] 1.834-30.244, p = 0.005) and 1.058 (95% CI 1.002-1.123, p = 0.044), respectively. In the bradycardia with dexmedetomidine group, the infusion rate of dexmedetomidine was 0.41 +/- 0.15 microg/kg/h. Decisions of charged doctor's were 1) slowing infusion rate and 2) stopping infusion or administering atropine for bradycardia. No cases required cardiac pacing or worsened to asystole. CONCLUSIONS: Despite the frequent occurrence of bradycardia after administration of dexmedetomidine during 33degrees C target temperature management, bradycardia was completely recovered after reducing infusion rate or stopping infusion. However, reducing the infusion rate of dexmedetomidine lower than the standard maintenance dose could be necessary to prevent bradycardia from developing in patients with higher body weight or carbon monoxide poisoning during 33degrees C targeted temperature management.
Atropine ; Body Weight ; Bradycardia* ; Carbon Monoxide Poisoning ; Dexmedetomidine* ; Diagnosis ; Emergency Service, Hospital ; Heart Arrest ; Humans ; Hypothermia, Induced ; Logistic Models ; Odds Ratio ; Retrospective Studies

A clinical observation was performed on the 80 cases of neonates born from diabetic mothers among the total of 34,936 neonates delivered at II Sin Christian Hospital from January 1985 to December 1989. The results were as follows: 1) The incidence of infants of diabetic mothers was 0.23%, among whom gestational diabetic mothers were 63 cases (78.7%) and overt diabetic mothers were 17 cases (21.3%). 2) Among the complications of pregnancy and delivery, preeclampsia was most frequent as 33.8%, following by urinary tract infection (13.8%), polyhydramnios (1.3%), diabetic ketoacidosis (1.3%). 3) According to the gestational age, prematurity was 11.3%, full term 78.7% and post term 10%. And according to the growth state, small for date infants were 11.3%, appropriate for date infants 53.7% and large for date infants 35%. 4) The incidnece of giant babies (over 4,000 gm) was 30.0% and sex ratio of male to female was 1.1:1 in infants of diabetic mothers. 5) The most frequent clinical manifestation was tachypnea (45.3%), following by poor feeding (20.0%), cyanosis (18.7%). 6) According to the laboratory findings, 53.7% showed hypoglycemia, 36.3% hyperbilirubinemia, 25% hypocalcemia, 15% polycythemia. 7) On the chest X-ray, there were pulmonary infiltration and hyaline membrane disease in 3.2% each other and pulmonary congestion and wet lung in 1.6% each other. 8) The incidence of congenital anomaly was 13.8% in 80 cases of infants of diabetic mothers, and congenital heart disease was most frequent as 3 cases.
Cyanosis ; Diabetic Ketoacidosis ; Estrogens, Conjugated (USP) ; Female ; Gestational Age ; Heart Defects, Congenital ; Humans ; Hyaline Membrane Disease ; Hyperbilirubinemia ; Hypocalcemia ; Hypoglycemia ; Incidence ; Infant* ; Infant, Newborn ; Male ; Mothers* ; Polycythemia ; Polyhydramnios ; Pre-Eclampsia ; Pregnancy ; Pulmonary Edema ; Sex Ratio ; Tachypnea ; Thorax ; Urinary Tract Infections

This study was carried out to investigate the relationship between diabetic control and related factors of the practice of diet therapy which affects mostly diabetic patients' dietary compliance. A questionnaire survey was conducted on 128 diabetic patients who had visited Internal medicine endocrinology clinic at University Medical Center of Daegu area. The questionnaires including clinical characteristics, meal regularity and food intake which shows dietary compliance, intrinsic barriers to the practice of diet therapy and knowledge of diet therapy were asked and analyzed. The factor which affects HbA1c was intrinsic barriers and HbA1c became higher as the level of intrinsic barriers was increasing. The education on diet therapy had no influence on the intrinsic barriers, but the level of knowledge on diet therapy was shown higher in the educated patients. The above results suggest that the practice of diet therapy should be leaded to develop behavioral aspects through resonable motivation on dietary compliance along with removing intrinsic barriers rather than simply providing information.
Academic Medical Centers ; Compliance* ; Daegu ; Diet Therapy ; Eating ; Education ; Endocrinology ; Humans ; Internal Medicine ; Meals ; Motivation ; Surveys and Questionnaires

PURPOSE: Benign Convulsions with mild Gastroenteritis(CwG) were first reported in Japan by Morooka in 1982. The condition is recognized as a distinct clinical entity. It is characterized by previously healthy infants and young children aged 6 months to 3 years having afebrile brief generalized tonic-clonic convulsions between the first and the fifth sick days of viral gastroenteritis usually in winter. The patients are less than 5% dehydrated and the seizures tend to occur repetitively over several days with no eleptic discharges in the interictal electroencephalograms. The tests for rotavirus antigens in stool are frequently positive and other laboratory results are normal including cerebrospinal fluid, serum electrolytes and blood glucose. Also, they are known to have a good prognosis. The study intends to compare the clinical symptoms of CwG with normal body temperature and with high body temperature because mild gastroenteritis can induce fever. METHODS: The subjects were 42 patients diagnosed as GwG, who were admitted to Soonchunhyang University Hospital from May 2003 to March 2006. A Cohort study was performed and their characteristics were examined in terms of frequency, sex, age, monthly distribution, body temperature, days in hospital, seizure tups and duration, number of convulsions in one gastroenteritis period, family history, past history, and other symptoms of gastroenteritis RESULTS: The Total number of patients with gastroenteritis in the period were 635 and only 42(6.6%) patients were diagnosed as CwG. The mean age was 17.1+/-4.7 months, and it commonly occurs in winter. the typical symptoms of gastroenteritis were vomiting and diarrhea with 34(81.0%) patients having both symptoms simultaneously. Less vomiting and more diarrhea were noticed after seizure. Rotavirus antigens were positive in 18(51.4%) patients, and the number of seizures was 2.0+/-1.3 times during one gastroenteritis period. There were found no statistical differences in age, sex, days in hospital, seizure types and duration in those groups with and without fever and of pisitive and negative rotavirus antigens. CONCLUSION: CwG was defined as nonfebrile convulsions with gastroenteritis until nowadays, but there are no statistical differences between febrile and nonfebrile CwG. Therefore, febr ile seizures with gastroenteritis can be included in the same category of CwG.
Blood Glucose ; Body Temperature ; Cerebrospinal Fluid ; Child ; Cohort Studies ; Diarrhea ; Electroencephalography ; Electrolytes ; Fever ; Gastroenteritis* ; Humans ; Infant ; Japan ; Prognosis* ; Rotavirus ; Seizures* ; Sick Leave ; Vomiting

No abstract available.
Dwarfism*

PURPOSE: The purpose of this study was to examine whether there is difference in the effects of aromatherapy on dysmenorrhea by research design. METHODS: Findings from the two different research designs (Nonequivalent control group pretest-posttest [NCG] design vs. two-group crossover design) were compared in regard to the effect of aromatherapy on dysmenorrhea. The subjects of the NCG design and the crossover design were a total of 58 female nursing students. The treatments (aroma essential oil inhalation and carrier oil inhalation) were given using a necklace. The data were analyzed by Fisher's exact test, t-test, Mann-Whitney test, paired t-test, and Shapiro-Wilk test using the SPSS/WIN 12.0 program. The effect size for the two research designs was calculated. RESULTS: In both research designs, the level of dysmenorrhea and menstrual pain after the aroma treatment were not significantly different from those after the placebo treatment. The effect size of the NCG design was higher than that of the crossover design. CONCLUSION: Aroma inhalation may not be effective in managing dysmenorrhea and menstrual pain. In order to further clarify the efficiency of research design and the effect of aromatherapy on discomfort during menstruation, replication studies are necessary. Future studies need to examine the effects of different research design on non-interval variables.
Aromatherapy ; Cross-Over Studies ; Dysmenorrhea ; Female ; Humans ; Inhalation ; Menstruation ; Research Design ; Students, Nursing

Epidermolytic keratosis palmaris is a rare disease which shows clinical findings of Unna Thost keratoderma and histopathologic of epidermolytic hyperkeratosis. We report herein a case of epidermolytic keratosis palmaris et plantaris in a 16-month-old female baby. Light microscopy shows marked hyperkeratosis, large irregular keratohyalin granules, and large clear spaces in the granular and upper spinous layers. Eletron microscopic findings shows that the clear spaces are areas of cytoplasm filled with a fibrillar material and cellular organelles. Abnormal clumping of tonofilament and keratohyalin is also present.
Cytoplasm ; Female ; Humans ; Hyperkeratosis, Epidermolytic ; Infant ; Intermediate Filaments ; Keratoderma, Palmoplantar* ; Keratosis* ; Microscopy ; Organelles ; Rare Diseases