PURPOSE: Despite the well-known public health benefits of vaccination, increasing public concern about the safety of childhood vaccinations has led some parents to refuse or hesitate having their children immunized. The purpose of this study was to identify the subjectivity of parents toward refusal of childhood vaccination. METHODS: Q-methodology, in which subjective viewpoints are explored and analyzed using a combination of quantitative and qualitative techniques, was used. Thirty-five participants were asked to rank 42 statements on diverse issues of childhood vaccination according to a continuous 9-point scale ranging from -4 for strongly disagree to +4 for strongly agree. Collected data was analyzed using the PC-QUANAL program. RESULTS: The results revealed three discrete groups of parents in the refusal of children's immunization: type I, distrust; type II, concern about side effects, and type III, belief that vaccinations are unnecessary. CONCLUSION: Special nurse counselors who can provide correct information about vaccination based on the three types should be part of the government policy. Customized education programs to shift viewpoints should be also redeveloped according to the results in this study.
Child ; Counseling ; Disulfiram ; Humans ; Parents ; Public Health ; Rejection (Psychology) ; Vaccination

Objectives: Due to the prolonged coronavirus disease 2019 pandemic, prioritizing the safety and well-being of essential workers, who play a vital role in enabling contactless living, is paramount. This study aims to check oral health status and related factors in platform workers. Methods: The participants, who are platform workers in Seoul, were divided into three occupations: replacement driver, parcel, and delivery. The survey included oral examination and health-related questionnaires from August to November 2022. Finally, 204 platform workers in Seoul participated in the study. The socio-demographic characteristics of participants, such as sex, age, education level, and health behavior, were analyzed. A chi-square test and logistic regression analysis were performed to investigate the socio-demographic factors related to the need for dentures. Results: Most participants were men (97.5%), and in the age of 50s (33.8%). In total, the proportion of the need for dentures was 40.2%. It was high in the group of parcel, the 50s age group, and people without experience of the oral exam last year (P<0.05). The probability of needing dentures was 9.7 times higher in the 50s than in the 30s, and 2.3 times higher in the group without oral exam experience last year than the group with that experience. Conclusions Among the platform workers in Seoul, age and oral examination were related factors for denture needs. To promote the oral health of platform workers, the policy to increase oral examination should be implemented.

Stroke is one of the leading causes of death and physical disability among adults. It has been 15 years since clinical trials of stem cell therapy in patients with stroke have been conducted using adult stem cells like mesenchymal stem cells and bone marrow mononuclear cells. Results of randomized controlled trials showed that adult stem cell therapy was safe but its efficacy was modest, underscoring the need for new stem cell therapy strategies. The primary limitations of current stem cell therapies include (a) the limited source of engraftable stem cells, (b) the presence of optimal time window for stem cell therapies, (c) inherited limitation of stem cells in terms of growth, trophic support, and differentiation potential, and (d) possible transplanted cell-mediated adverse effects, such as tumor formation. Here, we discuss recent advances that overcome these hurdles in adult stem cell therapy for stroke.
Adult Stem Cells* ; Adult* ; Biocompatible Materials ; Bone Marrow ; Cause of Death ; Humans ; Mesenchymal Stromal Cells ; Stem Cells ; Stroke*

PURPOSE: This study was done to identify predictors differentiating the preparation stage, which is the stage that the smoker is ready to quit smoking, between adolescent smokers and adult smokers. METHOD: A survey was conducted with 376 adolescent smokers in 4 high schools and 451 adult smokers in community settings in South Korea from August 2003 to April 2005. To identify the predictors before and after preparation in stages of change of smoking, logistic regression was done. RESULTS: The predictors for before preparation in stages of change of smoking were process of change for smoking abstinence for adolescent smokers and depression for adult smokers. The predictors for after preparation in stages of change of smoking were self-efficacy for smoking abstinence for adolescent smoker and self-efficacy for smoking abstinence and smoking temptation for adult smokers. CONCLUSION: For each group, adolescent smokers and adult smokers, specific smoking intervention methods need to be developed based on the different ways individuals make the decision to quit smoking within their contexts.
Adolescent* ; Adult* ; Depression ; Humans ; Korea ; Logistic Models ; Smoke* ; Smoking*

Erlotinib is accepted as a standard second-line chemotherapeutic agent in patients with non-small cell lung cancer who are refractory or resistant to first-line platinum-based chemotherapy. There has been no previous report of bowel perforation with or without gastrointestinal metastases related to erlotinib in patients with non-small cell lung cancer. The exact mechanism of bowel perforation in patients who received erlotinib remains unclear. In this report, we report the first case of enterocutaneous fistula in a female patient with metastatic non-small cell lung cancer 9 months, following medication with erlotinib as second-line chemotherapy.
Aged ; Antineoplastic Agents/*adverse effects/therapeutic use ; Carcinoma, Non-Small-Cell Lung/complications/*drug therapy ; Female ; Humans ; Intestinal Fistula/*chemically induced/complications/radiography/surgery ; Intestinal Perforation/*chemically induced/complications/radiography/surgery ; Protein Kinase Inhibitors/*adverse effects/therapeutic use ; Quinazolines/*adverse effects/therapeutic use ; Sigmoid Diseases/*chemically induced/complications/radiography/surgery

Objectives: With the rapid aging of the Korean population, interest in oral health is increasing among older adults. However, information and communication technology (ICT)-based programs for oral function rehabilitation exercises (OFRE), that are closely related to the systemic and cognitive health of older adults, are limited. Therefore, this study aimed to determine the applicability of ICT-based OFRE programs by identifying the demand from elder-care facility workers, who are the main providers, and to establish a basic plan for system development. Methods: This study was conducted using a Google Form questionnaire for approximately one month in September 2022 for workers at a day-and-night care center in Korea. Frequency analysis and chi-square tests were performed to identify the oral-health perceptions of center workers, and logistic regression analysis was performed to identify the need for ICT-based OFRE programs. Results: First, in patients undergoing oral function-related activities at the center, the need for OFRE was high, especially for mastication exercises (P<0.05). Second, participants with experience in using ICT-based rehabilitation programs were more positive about the usefulness of the new programs (P<0.001). Third, ease of use and simplicity of the program content were highly desirable, and group delivery was preferred. Conclusions This study confirmed the usefulness of ICT-based OFRE programs in facilities for older adults. The study findings are expected to be a basis for further development.

Objectives: With the rapid aging of the Korean population, interest in oral health is increasing among older adults. However, information and communication technology (ICT)-based programs for oral function rehabilitation exercises (OFRE), that are closely related to the systemic and cognitive health of older adults, are limited. Therefore, this study aimed to determine the applicability of ICT-based OFRE programs by identifying the demand from elder-care facility workers, who are the main providers, and to establish a basic plan for system development. Methods: This study was conducted using a Google Form questionnaire for approximately one month in September 2022 for workers at a day-and-night care center in Korea. Frequency analysis and chi-square tests were performed to identify the oral-health perceptions of center workers, and logistic regression analysis was performed to identify the need for ICT-based OFRE programs. Results: First, in patients undergoing oral function-related activities at the center, the need for OFRE was high, especially for mastication exercises (P<0.05). Second, participants with experience in using ICT-based rehabilitation programs were more positive about the usefulness of the new programs (P<0.001). Third, ease of use and simplicity of the program content were highly desirable, and group delivery was preferred. Conclusions This study confirmed the usefulness of ICT-based OFRE programs in facilities for older adults. The study findings are expected to be a basis for further development.

Objectives: With the rapid aging of the Korean population, interest in oral health is increasing among older adults. However, information and communication technology (ICT)-based programs for oral function rehabilitation exercises (OFRE), that are closely related to the systemic and cognitive health of older adults, are limited. Therefore, this study aimed to determine the applicability of ICT-based OFRE programs by identifying the demand from elder-care facility workers, who are the main providers, and to establish a basic plan for system development. Methods: This study was conducted using a Google Form questionnaire for approximately one month in September 2022 for workers at a day-and-night care center in Korea. Frequency analysis and chi-square tests were performed to identify the oral-health perceptions of center workers, and logistic regression analysis was performed to identify the need for ICT-based OFRE programs. Results: First, in patients undergoing oral function-related activities at the center, the need for OFRE was high, especially for mastication exercises (P<0.05). Second, participants with experience in using ICT-based rehabilitation programs were more positive about the usefulness of the new programs (P<0.001). Third, ease of use and simplicity of the program content were highly desirable, and group delivery was preferred. Conclusions This study confirmed the usefulness of ICT-based OFRE programs in facilities for older adults. The study findings are expected to be a basis for further development.

Objectives: With the rapid aging of the Korean population, interest in oral health is increasing among older adults. However, information and communication technology (ICT)-based programs for oral function rehabilitation exercises (OFRE), that are closely related to the systemic and cognitive health of older adults, are limited. Therefore, this study aimed to determine the applicability of ICT-based OFRE programs by identifying the demand from elder-care facility workers, who are the main providers, and to establish a basic plan for system development. Methods: This study was conducted using a Google Form questionnaire for approximately one month in September 2022 for workers at a day-and-night care center in Korea. Frequency analysis and chi-square tests were performed to identify the oral-health perceptions of center workers, and logistic regression analysis was performed to identify the need for ICT-based OFRE programs. Results: First, in patients undergoing oral function-related activities at the center, the need for OFRE was high, especially for mastication exercises (P<0.05). Second, participants with experience in using ICT-based rehabilitation programs were more positive about the usefulness of the new programs (P<0.001). Third, ease of use and simplicity of the program content were highly desirable, and group delivery was preferred. Conclusions This study confirmed the usefulness of ICT-based OFRE programs in facilities for older adults. The study findings are expected to be a basis for further development.

PURPOSE: This purpose of this study was to develop evidence-based practice guideline for isolation in health care settings to prevent transmission of infectious diseases utilizing guideline adaption process. METHODS: The process of guideline adaptation was performed according to the Korean hospital nurses association's guideline adaptation manual which consisted of three main phases, 9 modules, and 24 steps. RESULTS: The adapted isolation guideline consisted of introduction, overview of isolation guideline, summary of recommendations, recommendations, references, and appendices. The guideline includes 224 recommendations in 4 sections which are organizational administration, standard precautions, transmission-based precautions, and education/counselling. CONCLUSION: The adapted isolation guideline is recommended to be disseminated and utilized by nurses and clinicians nationwide to improve the isolation practices for infected or colonized patients with communicable diseases and to decrease the transmission of infections in the healthcare settings.
Colon ; Communicable Diseases ; Delivery of Health Care ; Disease Transmission, Infectious ; Evidence-Based Nursing ; Evidence-Based Practice ; Humans ; Infection Control ; Patient Isolation