Dyke-Davidoff-Masson syndrome is a rare clinical syndrome consisting of hemiatrophy of cerebral hemisphere, enlargement of ventricles and prominent pneumatization of petrous pyramid of the temporal bone. Its clinical manifestations are hemiparesis, several types of seizure, mental retardation and other neurologic deficits. We experienced a case of Dyke-Davidoff-Masson syndrome in a four months old boy who visited to our department due to right side upper extremity weakness and infantile spasm. The brain magnetic resonance imaging showed marked hemiatrophy of left cerebral hemisphere and enlargement of left lateral ventricle. So with the review of literatures, we report a case of Dyke-Davidoff-Masson syndrome with infantile spasm.
Brain ; Cerebrum ; Humans ; Infant ; Infant, Newborn ; Intellectual Disability ; Lateral Ventricles ; Magnetic Resonance Imaging ; Male ; Neurologic Manifestations ; Paresis ; Petrous Bone ; Seizures ; Spasms, Infantile* ; Temporal Bone ; Upper Extremity

BACKGROUND: Eosinophil cationic protein (ECP), one of the eosinophil granule proteins released during allergic reactions, may play a major role in the allergic inflammatory process. The measurement of ECP in serum may be a useful indicator of eosinophil activity in ongoing inflammatory processes. We investigated the clinical utility of ECP measurement in serum in patients with bronchial asthma, allergic rhinitis and atopic dermatitis, after standardizing sample processing. METHODS: We measured the serum ECP levels in patients with bronchial asthma (n=38), chronic obstructive pulmonary diseases (COPD) (n=13), respiratory symptoms (n=19), allergic rhinitis (n=26), non-allergic rhinitis (n=24), and atopic dermatitis (n=10) and in normal healthy controls (n=16) by the fluoroenzyme immunoassay using Pharmacia CAP System, and evaluated the correlation between ECP level and blood eosinophil number, or ECP and IgE levels. Blood eosinophil number was counted by the automated cell counter. RESULTS: Serum ECP levels were significantly higher in patients with bronchial asthma (15.6+/- 12.6 g/L), COPD (13.3+/-7.2 g/L), allergic rhinitis (23.8+/-13.2 g/L), and atopic dermatitis (20.6+/- 18.4 g/L) than in normal controls (7.5+/-4.2 g/L) (P <0.05). ECP levels were also significantly higher in patients with bronchial asthma and COPD than in patients with simple respiratory symptoms (6.9+/-4.7 g/L), whose ECP levels did not statistically differ from those in normal controls. ECP levels were also significantly higher in patients with allergic rhinitis than in patients with non-allergic rhinitis (9.5+/-5.1 g/L), whose ECP levels did not statistically differ from those in normal controls. Serum ECP level and eosinophil number in peripheral blood were correlated only in patients with bronchial asthma (r=0.53, P <0.01) and no correlation between ECP and IgE levels was found in all of the patients. CONCLUSIONS: ECP is the one of the secretory components released from the eosinophil granule and measurement of ECP in serum might be one of the noninvasive tool to assess the activity in relation to eosinophil involvement in various allergic diseases.
Asthma ; Cell Count ; Dermatitis, Atopic ; Eosinophil Cationic Protein* ; Eosinophil Granule Proteins ; Eosinophils ; Humans ; Hypersensitivity ; Immunoassay ; Immunoglobulin E ; Lung Diseases, Obstructive ; Pulmonary Disease, Chronic Obstructive ; Rhinitis

Recently, CT scan, CT sialogram, radionuclide imaging and ultasonogram are widely applicated in conjuctionwith conventional studies such as plain film, sialogram and arteriogram for the diagnosis of salivary glanddisease. Among them, ultrasonogram porvides safe, noninvasive, and reliable way to diagnose salivary glanddisease. Authors evaluated ultrasonographic and sialographic findings of patients with suspected salivary glanddisease in 16 cases at Korea University Hosital for 8 months. (from Dec. 1983 to Aug. 1984). The following resultsare observed. 1. Final diagnosis of 16 cases were 2 cases of stone, 1 case of pleomorphic adenoma, 2 cases ofneurilemmoma, 3 cases of chronic sialademitis, 1 case of abscess, 2 cases of Retention cyst, 1 case of psendocyst,1 case of tuberculous lymphadenopathy, and 3 cases of normal finding. 2. Diagnostic ultrasonogram providesaccurate information for the size, location and character of the lesion, and differentiates intragladular lesionsfrom extraglandular ones. 3. Ultrasonogram is one of convenient, reliable and initial modality for the diagnosisof salivary gland disease.
Abscess ; Adenoma, Pleomorphic ; Diagnosis ; Humans ; Korea ; Lymphatic Diseases ; Radionuclide Imaging ; Salivary Gland Diseases ; Salivary Glands ; Tomography, X-Ray Computed ; Ultrasonography

Intracranial developmental venous anomalies (DVAs) are the most common cerebral vascular malformation and are usually asymptomatic. Movement disorders are rarely associated with DVAs within basal ganglia regions. We report a case of markedly asymmetric parkinsonism due to unilateral DVA in the basal ganglia, which occurred together with symmetrical nigrostriatal dopaminergic deficits. A 57-year-old woman presented with resting tremor in the right hand lasting for 6 months. She also experienced problems with gait and started falling while walking one month ago. The neurological examination found a resting tremor in the right hand and moderate rigidity and bradykinesia in the right extremities. She reported light headedness on standing up. The patient displayed minimal response to treatment with 300 mg levodopa. The FP-CIT PET scan revealed symmetrical decrease of radiotracer uptake in bilateral basal ganglia. Brain MRI and cerebral angiography identified a large DVA draining the basal ganglia, thalamus, and surrounding deep white matter in the left side. Conclusion: A DVA may contribute to the prominent asymmetrical manifestation in our patient, in combination with symmetrical dopaminergic loss from neurodegenerative Parkinsonian syndrome. A marked asymmetry in patients with signs of atypical Parkinsonism can be a clue for further imaging investigation to exclude superimposed structural lesions such as DVAs.

Septo-optic dysplasia, as first described by de Morsier, is a rare developmental anomaly of absent or hypoplastic septum pellucidum, a primitive optic vesicle, and dysplasia of the optic nerve, chiasm, and optic tracts. It is a common cause of hypopituitarism in children and has variable hypothalamic-pituitary dysfunction. We experienced a case of septo-optic dysplasia in 5 month old female baby who presented with developmental delay and seizure. A magnetic resonance imaging of the brain showed absence of the septum pellucidum and the fundoscopic examination disclosed the absence of left optic disc and atrophy of right optic disc.
Atrophy ; Brain ; Child ; Female ; Humans ; Hypopituitarism ; Infant ; Magnetic Resonance Imaging ; Optic Nerve ; Seizures ; Septo-Optic Dysplasia* ; Septum Pellucidum ; Visual Pathways

PURPOSE: The purpose of this study was to identify the influencing factors on osteoarthritis in Korean. METHOD: Data from the Fourth Korean National Health and Nutrition Examination Survey(KNHANESIV-3, 2009) were obtained, and 1,116 subjects who responded certainly yes or no to the question for osteoarthritis were selected. Data were analyzed chi2-test, t-test, and binary logistic regression using the SPSS V18.0. RESULTS: Significant differences in gender, age, menopause, weight, BMI, frequency of walk, days of flexibility exercise, days of strength training, and limitation of activity were found between subjects with osteoarthritis and non-osteoarthritis. Age and BMI were found to be risk factors for osteoarthritis in Korean. CONCLUSION: This study suggested that nursing intervention should include weight control program for the obesity patient in order to reduce the prevalence of osteoarthritis.
Female ; Humans ; Logistic Models ; Menopause ; Obesity ; Osteoarthritis ; Pliability ; Prevalence ; Resistance Training ; Risk Factors

Gastric cancer is the most common gastrointestinal malignancy in Korea. Identification and evaluation ofgastric mass lesions and regional-distant metastases by abdominal CT scan are important for the treatment planningand prognostic implications of gastric cancer patients. Author reviewed CT scan are important for the treatemntplaning and prognostic implications of gastric cancer patients. Author reviewed CT scan of 61 cases of pathologyproven gastric cancer, retrospectively, for recent 20 months from July 1983 to Feb. 1985 at department ofradiology, Korea University, Hae Wha Hospital. The results were as follows: 1. There were 50 cases of advanced adenocarcinoma, 8 cases of early gastric cancer, 2 cases of leiomyosarcoma, and 1 case of lymphoma in total 61cases. 2. The sex ratio of male to female was 2:1. Age distribution was from 24 to 75 year old and peak incidencewas in 6th decade. 3. The most frequent site of involvement with gastric cancer was gastric antrum in 51%. 4. 48of the 50 patients with advanced gastric adenocarcinoma(96%) had a wall thickness greater than 1 cm, and all of 8cases of early gastric cancer had a wall thickness less than 1 cm. Regional lymph node tumor infiltration wasfound in 100% of gastric wall thickness greater than 2.0cm, in 64% of cases of 1.5 to 2.0cm, in 50% of cases of1.9 to 1.5cm, and 12.5% of cases of less than 1.0cm. 5. In a comparison of enlargement of reginal lymph node by CTscan to tumor infiltration of regional lymph node by histology, senitivity was 52%, specificity was 87%, and reliability was 66%. 6. The structures involved by distant metastases of these cases were the retroperitoneallymph node in 15, liver in 8, and pancrease in 3. 7. The diagnostic accuracy of CT staging was considered about68% by correlation of the surgical and histological findings. 8. The CT scan is one of the accurate and simpletool for evaluation of size, shape, extent, as well as distant metastases in the cases of gastric malignancies.
Adenocarcinoma ; Age Distribution ; Female ; Humans ; Korea ; Leiomyosarcoma ; Liver ; Lymph Nodes ; Lymphoma ; Male ; Neoplasm Metastasis ; Pancreas ; Pancrelipase ; Pyloric Antrum ; Retrospective Studies ; Sensitivity and Specificity ; Sex Ratio ; Stomach Neoplasms ; Tomography, X-Ray Computed

PURPOSE: To determine the cross sections of extraocular muscles in patients with orbital fracture and to demonstrate a relationship among the cross sections, the size of orbital fracture, the soft tissue, and fat herniation and limitation of ocular movement. METHODS: The study included 87 patients (87 eyes) with orbital fracture. The cross section was defined as multiplication of the long axis and short axis. The ratio of the cross section in normal and injured eyes was calculated at preoperative and postoperative periods. RESULTS: The cross sections of all rectus muscles, except for the superior, increased in injured eyes and subsequently decreased postoperatively. After surgery, the cross sections of lateral and medial rectus muscles recovered to near normal but the inferior remained enlarged. The increased ratio of the short and long axis was significant but not the difference of the cross sections related to the short and long axis ratio. There was a preoperative difference between injured/normal cross section ratio in relation to the size of inferior fracture. There was postoperative normalization for the cross sections of inferior rectus muscles with the restrictive limitation due to inferior fracture. CONCLUSIONS: The cross sections increased mostly after orbital fracture and subsequently decreased postoperatively. There was a change in the cross section ratio with the size of inferior fracture at preoperative period but there was no change in the cross sections related to the restrictive or paralytic limitation, except for eyes with the restriction secondary to inferior fracture. These were significantly normalized postoperatively in cross section.
Axis, Cervical Vertebra ; Eye ; Humans ; Muscles ; Orbit ; Orbital Fractures ; Postoperative Period ; Preoperative Period