Primary renal lymphoma is a rare tumor of the kidney that typically presents with bilateral nodular enlargement in the absence of extrarenal masses. We describe MR findings of a case of primary renal lymphoma along with ultrasound and CT findings. MR imaging demonstrated globular enlargement of both kidneys with multilobulated contour and multiple masses which had isosignal intensity on T1WI and low signal intensity on T2WI. The masses enhanced slightly on dynamic contrast enhanced scan.
Kidney ; Lymphoma* ; Magnetic Resonance Imaging ; Ultrasonography

No abstract available.
B-Lymphocytes* ; Humans*

No abstract available.
Anemia, Aplastic* ; Leukemia, Myeloid, Acute*

Spontaneous pneumothorax is a known, but relatively rare complication of pulmonary metastases of sarcoma. A 19-year-old man was presented with chest pain and dyspnea for three days and was diagnosed as left pneumothorax. After bleb resection, microscopic examination revealed metastatic osteosarcoma forming subpleural fistula and dystrophic calcification. Four years ago, he had had limb salvage operation and chemotherapy for osteosarcoma of left femur. After two and a half years he had a bleb resection for right pneumothorax without any evidence of metastasis. Six months later, he was found to have a 4x3cm sized lung mass in the right lower lobe. After lobectomy, he was diagnosed as pulmonary metastasis of osteosarcoma. Pneumothorax is the common complication of metastatic osteosarcoma to the lung and it may be presented before the pulmonary metastasis is clinically evident. It is important to recognize a pneumothorax of the patients with osteosarcoma as a possible sign of metastases.
Blister ; Chest Pain ; Drug Therapy ; Dyspnea ; Femur ; Fistula ; Humans ; Limb Salvage ; Lung ; Neoplasm Metastasis* ; Osteosarcoma* ; Pneumothorax* ; Sarcoma ; Young Adult

BACKGROUND/OBJECTIVES: The purpose of this study is to analyze daily kimchi, vegetable and fruit consumption by general characteristics and vegetable and fruit consumption from 1998 to 2012 by the Korean population based on the data of the KNHANES (Korea National Health and Nutrition Examination Survey). SUBJECTS/METHODS: This study is based on the 1998-2012 KNHNES. Analysis data on 54,700 subjects aged 19 years and older were obtained from health behavior interviews and the 24-hour dietary recall method. RESULTS: Daily kimchi consumption and portion size of kimchi decreased significantly from 1998 to 2012 (adjusted P for trend < 0.0001). Meanwhile, daily consumption of both non-salted vegetable and fruit with and without kimchi did not significantly change between 1998 and 2012. Reduced consumption of kimchi, non-salted vegetable, and fruit was observed for both genders as well as daily meal episodes and cooking locations. Male and female subjects with insufficient non-salted vegetable and fruit intake were increased 1.4 times and 1.3 times, respectively, in 2012 than 1998. All subjects consumed at least 400 g/day of non-salted vegetable, fruit, and kimchi in each survey year, although they consumed insufficient amounts (< 400 g/day) of non-salted vegetable and fruit without kimchi. CONCLUSIONS: Since Koreans generally consume high amounts of fermented vegetables, including kimchi, total vegetables and fruit. Consumption of these foods by the Korean adult population reached 400 g, which is the recommended intake of the WCRF/AICR. Based on this result, it is necessary to promote consumption of kimchi in the Korean population and research the development of low sodium kimchi in the future.
Adult* ; Cooking ; Eating ; Female ; Fruit* ; Health Behavior ; Humans ; Korea* ; Male ; Meals ; Nutrition Surveys* ; Portion Size ; Sodium ; Vegetables*

We identified Charcot-Marie-Tooth disease type 1A (CMT1A) in a family with schwannomas in the spinal cord and median nerve. The CMT1A in this family showed an autosomal dominant pattern, like other CMT patients with PMP22 duplication, and the family also indicated a possible genetic predisposition to schwannomas by 'mother-to-son' transmission. CMT1A is mainly caused by duplication of chromosome 17p11.2-p12 (PMP22 gene duplication). A schwannoma is a benign encapsulated tumor originating from a Schwann cell. A case of hereditary neuropathy with liability to pressure palsies (HNPP) concurrent with schwannoma has been previously reported. Although it seems that the co-occurrence of CMT1A and schwannomas in a family would be the result of independent events, we could not completely ignore the possibility that the coincidence of two diseases might be due to a shared genetic background.
Adolescent ; Adult ; Charcot-Marie-Tooth Disease/complications/*diagnosis/genetics ; Chromosomes, Human, Pair 17 ; Female ; Genetic Predisposition to Disease ; Humans ; Magnetic Resonance Imaging ; Male ; Median Neuropathy/*diagnosis/genetics ; Myelin Proteins/genetics ; Neurilemmoma/complications/*diagnosis/pathology ; Pedigree ; Peripheral Nervous System Neoplasms/*diagnosis/genetics ; Spinal Cord Neoplasms/*diagnosis/genetics

PURPOSE: Women with breast cancer diagnosed at an age of 40 years or younger have a greater prevalence of germline BRCA1 and BRCA2 mutations than the prevalence of women with breast cancer diagnosed at older ages. Several immunohistochemical characteristics have been identified in breast cancers from studies of Caucasian women with BRCA1/2 mutations having familial or early-onset breast cancers. The aim of this study is to determine whether early-onset breast cancer in BRCA1 or BRCA2 mutation carriers, who were not selected from a family history, could be distinguished by the use of immunohistochemical methods and could be distinguished from breast cancer in women of a similar age without a germline BRCA1 or BRCA2 mutation. We also analyzed the prognostic difference between BRCA1/2 related and BRCA1/2 non-related patients by the use of univariate and multivariate analysis. MATERIALS AND METHODS: Breast cancer tissue specimens from Korean women with early-onset breast cancers were studied using a tumor tissue microarray. Immunohistochemical staining of estrogen receptor (ER), progesterone receptor (PR) and HER-2, as well as the histology and grade of these specimens, were compared. The prognostic impact of immunohistochemical and histological factors as well as the BRCA1/2 mutation status was investigated separately. RESULTS: There were 14 cases and 16 deleterious BRCA1/2 mutations among 101 patients tested. A family history (4/14) and bilateral breast cancers (3/9) were high risk factors for BRCA1/2 mutations. BRCA1/2- associated cancers demonstrated more expression of ER-negative (19.4% versus 5.1%, p=0.038) and HER-2 negative than BRCA1/2 negative tumors, especially for tumors with BRCA1 tumors The BRCA1/2 mutation rate for patients with triple negative tumors (negative expression of ER, PR and HER-2) was 24.2%. Tumor size, nodal status, and HER-2 expression status were significantly associated with disease free survival, as determined by univariate and multivariate analysis, but the BRCA1/2 status was not a prognostic factor. CONCLUSION: Breast cancer that occurs in women with a germline BRCA1 or BRCA2 mutations have recognizable immunohistochemical features, which may be useful in identifying individuals that are more likely to carry germline mutations. Although the BRCA1/2 mutation status was not a prognostic factor in Korean women with early-onset breast cancer, more cases with a longer follow-up period are needed for further study.
Female ; Humans ; Risk Factors ; Breast Neoplasms

PURPOSE: The purpose of this study was to evaluate the possibility of utilizing magnetic resonance angiography(MRA) in patients with cerebral infarction by comparative analysis of magnetic resonance imaging(MRI). MATERIALS AND METHODS: MRI and MRA using 3D time-of-flight(TOF) technique with magnetization transfer and ramp(MTR) or 3D TOF with multiple overlapping thin slab acquisition(MOTSA) were performed in 39 patients with cerebral infarction. Vascular lesions detected on MRA were classified as "normal", "stenosis" and "occlusion", and the different infarction sites were named according to their vascular territory. Correlation between MRI and MRA findings was evaluated. RESULTS: In 24(62%) of 39 cases, MRA showed stenosis or occlusion and 19(86%) of those corresponded to their vascular territory of infarction, as visualized on MRI. In 15(62.5%) of the 24 cases, MRA revealed additional diagnostic information such as visualization of unpredicted vascular lesions orthe presence of collateral circulations. Of the 15 cases diagnosed as normal according to MRA, most of the mactually had small infarctions of less than 2cm in maximal dimension in the area of the perforating arteries. CONCLUSION: There was a strong correlation between the vascular lesion observed by MRA and the distribution of the infarct areas on MRI. Additional information was provided by MRA obtained together with conventional MRI.
Arteries ; Cerebral Infarction* ; Collateral Circulation ; Constriction, Pathologic ; Humans ; Infarction ; Magnetic Resonance Imaging*

Pericardial defect is a rare congenital cardiac disorder. Most patients were asymptomatic but some patients with partial pericardial defect occasionally complain acute symptoms such as angina, syncope, rarely sudden cardiac death. So, differential diagnosis with other ischemic or structural heart disease is crucial in the management of such patients. But there is no consistently successful diagnostic method. In the past, artificial diagnostic pneumothorax was used to document the absence of pericardium. However, it is not easily accepted due to excess morbidity and failure rate. Recently, echocardiography and more often, computed tomography, magnetic resonance imaging are used to confirm the diagnosis. We experienced a 52 years old male patient with atypical chest pain, who was diagnosed as complete left pericardial defect with computed tomography.
Chest Pain ; Death, Sudden, Cardiac ; Diagnosis ; Diagnosis, Differential ; Echocardiography ; Heart Diseases ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Pericardium ; Pneumothorax ; Syncope

PURPOSE: To investigate the differences in signal changes in the globus pallidus and white matter, as seen on T1-weighted MR brain images, and to determine whether these differences can be used as an indicator of subclinical hepatic encephalopathy. MATERIALS AND METHODS: A total of 25 cases of liver cirrhosis were evaluated.and as a control group, 20 subjects were also studied. Using a 1.5T MRI scannet, brain MR images were btained, and the differences in signal intensity in both the globus pallidus and thalamus and in both white and gray matter were then quantified using the contrast to noise ratio(CNR). On the basis of the Child-Pugh classification, 25 patients with liver cirrhosis were divided into three groups, with eight in group A, eight in B, and nine in C. Using clinical criteria, hepatic encephalopathywas diagnosed in seven of the 25 patients. Thereafter, CNRs(CNR1 and CNR2) were conpared between the control and cirrhotic groups and between cirrhotic groups with or without hepatic encephalopathy. RESULTS: In the control group, mean values were 3.2 +/-5.9 for CNR1 and 8.4 +/-8.0 for CNR2. In the cirrhotic group, these values were 10.6 +/-9.0 for CNR1 and 9.8 +/-6.4 for CNR2. A statistically significant difference was noted between normal and cirrhotic groups only for CNR1(p < 0.05). CNR values in patients with liver cirrhosis were 8.5 +/-11.5 for CNR1 and 11.7 +/-8.7 for CNR2 in the Child A group, 10.4 +/-5.1 for CNR1 and 9.3 +/-3 . 2 for CNR2 in the B group, and 12.8 +/-9.7 for CNR1 and 8.7 +/-6.5 for CNR2 in the C group. There was no significant difference in mean CNRI values between patients with or without hepatic encephalopathy. CONCLUSION: Differences in signal intensities in the globus pallidus and white matter, as seen on T1-weighted MR brain images, cannot be used as an indicator of hepatic encephalopathy in patients with liver cirrhosis.
Brain ; Child ; Classification* ; Evaluation Studies as Topic* ; Globus Pallidus ; Hepatic Encephalopathy* ; Humans ; Liver Cirrhosis* ; Liver* ; Magnetic Resonance Imaging* ; Noise ; Thalamus