2.Increased expression of the epidermal growth factor receptor gene in psoriasis.
Yoon Yae CHOI ; Kyu Suk LEE ; Sang Sook LEE ; Eun Sook CHANG ; Jun Young SONG
Korean Journal of Dermatology 1992;30(4):431-438
Psoriasis is characterized by disregulation of keratinocyte growth with profound epidermal hyperplasia. Keratinocyte hyperplasia in psoriasis may be expained in part by overproduction of growth factor, and by altered metabolism of the epidemal growth factor receptors (EGFR) in affected skin. The expression of epidermal growth f ictor receptor was investigated by Northern blot and slot-blot analysis of total RNA extrated from biopsies of normal skin and psoriatic lesions. In Northern blot analysis, EGFR-specific mRNA transcripts from psoriatic tissues demonstrated the specificity of hybridizarion with a EGFR mDNA probe. The size of EGFR mRNA transcript was 6.7kb in psoriasis lesions which showed no change of quality. In slot-blot analysis, the levels of EGFR mRNA in poriasis revealed a 1.2 fold to 4.1 fold elevation when compared to normal skin. EGFR were present in all epidermal layers by immunoperoxidase staining, whereas in normal skin they were primarily present in the stratum basalis. These results indicate that the increased expresion of the EGFR gene may be, in part, responsible for the hyperproliferation of the epider nis and that retained EGFR may reflect incomplet; abnormal differentiation in active porasis. This altered process of EGFR metabolism may be involved in the pathogenesis of psoriasis.
Biopsy
;
Blotting, Northern
;
Epidermal Growth Factor*
;
Genes, erbB-1
;
Hyperplasia
;
Keratinocytes
;
Metabolism
;
Psoriasis*
;
Receptor, Epidermal Growth Factor*
;
Receptors, Growth Factor
;
RNA
;
RNA, Messenger
;
Sensitivity and Specificity
;
Skin
3.Inter-generation Occupational Mobility Experience of Nurses: Focus on Mother's Experience.
Joo Hyun KIM ; Eun Sook NAM ; Myung Sook KIL ; Sung Ja YOON ; Eun Jin SOUN ; Eun Young PARK
Journal of Korean Academic Society of Nursing Education 2014;20(4):523-533
PURPOSE: The purpose of this study is to analyze how the experiences of nurses influence their role model function when they are mothers of children who in turn have become nurses or nursing students. METHOD: The subjects of this study were 12 nurses, 8 of their children who became nurses and another 4 children then in training to become one. Data were collected through in-depth personal interviews and subsequently analyzed through a phenomenological approach. RESULTS: Four main themes were identified as follows; 'Persuasion and dissuasion,' 'Proud but still pathetic,' 'As mom and senior nurse' and 'Great to pass it down.' CONCLUSION: The results of this study show that the nurse as mother could be a positive professional role model for her children. However, they tended to stress the arduous clinical routines and poor work conditions nurses currently experience. Should such routines and conditions improve, mothers who are nurses would be more willing to recommend the nursing profession to their children. Improving the professional environment is thus important because inter-generation nursing mobility provides a reliable resource to recruit qualified and dedicated nursing personnel.
Career Mobility
;
Child
;
Humans
;
Intergenerational Relations
;
Mothers
;
Nursing
;
Professional Role
;
Qualitative Research
;
Students, Nursing
4.The evaluation of functional status and quality of life of end stage renal failure patients undergoing hemodialysis in SNHA lifetimehealth monitoring program.
Hyun Sook KIM ; Yoon Mi WON ; Kyung Mi PARK ; Chae Gab LIM ; Ho Cheol SHIN ; Eun Sook PARK
Journal of the Korean Academy of Family Medicine 1992;13(5):450-459
No abstract available.
Humans
;
Quality of Life*
;
Renal Dialysis*
;
Renal Insufficiency*
5.The role of age and relative body weight on serum cholesterol.
Se Jung YANG ; Kang Sook LEE ; Kyoung Mi KIM ; Yoon Mi WON ; Ho Cheol SHIN ; Eun Sook PARK
Journal of the Korean Academy of Family Medicine 1991;12(4):26-32
No abstract available.
Body Weight*
;
Cholesterol*
6.Comparison of Double Maddox Rod Test and Bagolini Striated Lens Test for Superior Oblique Palsy.
Si Eun LEE ; Sook Hyun YOON ; Sook Young KIM
Journal of the Korean Ophthalmological Society 2016;57(5):837-842
PURPOSE: We compared the results of the double Maddox rod test (DMRT), which is commonly performed in clinics as a subjective torsion test for superior oblique muscle palsy, with those of the Bagolini striated lenses test (BSLT) in a least dissociating condition to predict the cyclofusional capacity. METHODS: Twenty-five patients with acquired superior oblique muscle palsy were tested for degree of subjective torsion with DMRT and BSLT in primary position and down-gaze in Daegu Catholic University Hospital from May 2014 to March 2015. DMRT was performed in a dark room and BSLT in a lighted room. RESULTS: Mean extorsional degree in primary position was 3.40 ± 2.58° on DMRT and 1.88 ± 2.92° on BSLT, a significant difference (p = 0.000). In down-gaze, mean extorsional degree was 4.16 ± 2.90° with DMRT and 2.40 ± 2.90° with BSLT (p < 0.001). CONCLUSIONS: The subjective torsional measurement with BSLT was significantly smaller than with DMRT, and the cyclofusional capacity in patients with acquired superior oblique palsy was 1.5° in primary position and 1.8° in down-gaze. BSLT is helpful in addition to DMRT and fundus photograph for the evaluation of cyclotropia in patients with superior oblique muscle palsy, and this test may yield clinically important information for predicting the cyclofusional capacity of patients with superior oblique muscle palsy.
Daegu
;
Humans
;
Paralysis*
7.The Effect of Acute Normovolemic Hemodilution on Cardiopulmonary Bypass in Coronary Artery Bypass Grafting Surgery.
Jeong Seon HAN ; Eun Sook YOO ; Seok Whan YOON ; Sook Young LEE
Korean Journal of Anesthesiology 1999;37(3):406-411
BACKGROUND: Systemic arterial hypotension is relatively common following initiation of cardiopulmonary bypass (CPB). Decreased blood viscosity is induced by acute normovolemic hemodilution (ANH) and by the use of crystalloid oxygenator prime. The purpose of this paper is to study the effect of ANH on mean arterial pressure, perfusion flow index and PaO2/FiO2 upon initiation of CPB, and on homologous blood usage during CPB in coronary artery bypass grafting (CABG) surgery. METHODS: We reviewed 30 patients constituting an ANH group, and 30 patients in a control group who had undergone CABG surgery within the past 2 years. In the ANH group, 1 or 2 units of fresh autologous whole blood were sequestrated following induction of anesthesia. We compared mean arterial pressure, perfusion flow index, PaO2/FiO2, and hematocrit on the initiation of CPB, and homologous blood usage during and post CPB periods between the groups. RESULTS: Upon initiation of CPB, hematocrit in the ANH group was significantly less than in the control group, but there was no significant difference in mean arterial pressure, perfusion flow index or PaO2/FiO2 between the groups. The use of homologous blood during CPB in the ANH group was not significantly higher than in the control group. CONCLUSIONS: Acute intraoperative normovolemic hemodilution in CABG surgery was safely performed without significant hypotension and increased homologous blood usage during CPB.
Anesthesia
;
Arterial Pressure
;
Blood Viscosity
;
Cardiopulmonary Bypass*
;
Coronary Artery Bypass*
;
Coronary Vessels*
;
Hematocrit
;
Hemodilution*
;
Humans
;
Hypotension
;
Oxygen
;
Oxygenators
;
Perfusion
8.A Comparision Between Fallopian Tube Sperm PerfusionFSP and Intrauterine InseminationIUI for the Treatment of Infertility.
Jong In LEE ; Young Moon HUR ; Eun Sook JEON ; Jung Im YOON
Korean Journal of Obstetrics and Gynecology 2000;43(12):2121-2126
No abstract available.
Fallopian Tubes*
;
Female
;
Infertility*
;
Spermatozoa*
9.A Case of Metatropic Dwarfism.
Eun Ok RHEE ; Nam Joo HWANG ; Yaung Sook CHOI ; Son Sang SEO ; Hye Kyoung YOON
Journal of the Korean Pediatric Society 1989;32(8):1167-1173
No abstract available.
Dwarfism*
10.Perception of Elementary School Teachers about Nutrition Education in the Kyungnam Area.
Hyun Sook YOON ; Jung Suk RO ; Eun Sik HER
Korean Journal of Community Nutrition 2001;6(1):84-90
The purpose of this study was to investigate teacher's perceptions about the nutrition education of elementary schools. A total of 226 elementary school teachers within Changwon and Milyang city participated in this study. The results of this study were as follows. 90.8% of the teachers responded that nutrition education is necessaty in the elementary schools, and positive responses in the Milyang urban area were higher than that of the Changwon rural area(p<0.001). The main reason for the necessity of nutrition education was for proper growth and good table manners and the Milyang urban city was significantly higher than three other classes in 'for proper growth'(p<0.05). The starting period for nutrition education was supported by 72.1% of the teachers as beging when the children are in kindergarten, proving that this early nutrition education is supported. Especially in the Changwon urban support was higher than in the three other classes(p<0.01). The perceptions about a suitable person to teach nutrition indicated parents(39.6%), dietitions(35.5%), class teachers(24.9%), and the beliefs about nutrition specialists or dietitions was very low. 53.6% of the teachers responded that they would not teach nutrition education themselves and the main reason for this was that believed the teacher's work would be too hard(32.0%), lack of nutrition knowledge(29.4%), and that such courses should be taught courses by specialists(29.4%). However, 51.6% of the teachers disagreed with having a separate course for nutrition education. Proper eating habits(62.7%) and growth and nutrition(28.6%) were the main categories within nutrition education. The teacher recognized that elementary students' nutrition problem is to eat too much processed and instant foods(39.1%), deviated foods(36.9%), and lack of table manners(19.4%). The most effect method was to link the subject matter with the parents(38.7%), use of audio visuals and education materials(28.3%), and need of nutrition education teachers(10.1%) was low.
Child
;
Eating
;
Education*
;
Gyeongsangnam-do*
;
Humans
;
Specialization