1.Effects of selective obstruction of intracranial venous sinuses on systemic arterial pressure, cerebral perfusion pressure, intracranial pressure and intrasinal pressure in cats.
Yeungnam University Journal of Medicine 1993;10(2):475-484
In order to evaluate the safe ligation time and sites of dural venous sinuses during neurosurgical operation, systemic arterial pressure(SAP), cerebral perfusion perssure(CPP), intracranial pressure (ICP) and intrasinal pressure(ISP) were measured in cats through neuromonitor before and after obstruction of anterior 1/3, middle 1/3, posterior 1/3 of the superior sagittal sinus and the results were as follows. There were no significant increases of pressures after obstruction of anterior 1/3 of the superior sagittal sinus. In the obstructed middle 1/3 of the superior sagittal sinus group, signifi6int increases were seen un the m-SAP within 2, 4 and 6 minutes, the m-ICP within 2-7 minutes, the r.i-ISP within 14 minutes after obstruction. In the -obstructed posterior 1/3 of the superior sagittal sinus group, there were significant increases of m-SAP within 2, 4 and 6 minutes, the m-ICP within 27 minutes, the m-ISP within 13 minutes. In the obstructed Torcular Herophili,group, there were significant increases of the m-SAP within 1-2 and 4-7 minutes, the m-ICP within 36 minutes and the m-ISP within 1-7 minuted and less significant dercreases of the m-CPP within 5-7 minutes after obstruction. In the obstructed right transverse sinus group, significant increases of the m-ICP and the m-ISP were seen within 1-7 minutes after obstruction. there were no remarkable changes in the obstructed left transverse sinus group.
Animals
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Arterial Pressure*
;
Cats*
;
Intracranial Pressure*
;
Ligation
;
Perfusion*
;
Superior Sagittal Sinus
;
United Nations
2.Digital Infrared Thermographic Imaging(D.I.T.I.) in Herniated Lumbar Disc Patients.
Young Soo KIM ; Yong Eun CHO ; Seong Hoon OH
Journal of Korean Neurosurgical Society 1990;19(10-12):1303-1313
Thermography is a sensitive and reliable method for diagnosis of radiculopathy. Skin temperature alterations of the involved dermatome named thermatone are diagnostic for sensory root involvement in radiculopathy which can be demonstrated by thermography. Digital infrared thermographic imaging system using computer is development and could measure thermal difference more exactly without hazards or discomforts to patient. Authors present 186 cases of thermographic evaluation in herniated lumbar disc disease by digital infrared thermographic imging system and the results are evaluated with literature review.
Diagnosis
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Humans
;
Radiculopathy
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Skin Temperature
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Thermography
3.The Correlations between Cardiorespiratory Fitness Levels and Body Mass Index, Metabolic Syndrome Risk Factors, Homeostasis Model Assessment-Insulin Resistance and High Sensitivity C-Reactive Protein in Male High School Students.
Soo Youn KIM ; Eun Sung KIM ; Jung Ho CHO
Korean Journal of Health Promotion 2011;11(4):227-233
BACKGROUND: The purpose of this study was to analyze the relationships between cardiorespiratory fitness and body mass index (BMI), metabolic syndrome risk factors, homeostasis model assessment-insulin resistance (HOMA-IR), and high sensitivity C-reactive protein (hsCRP) in male high school students in Korea. Furthermore, the effects of the cardiorespiratory fitness levels on these four factors were examined. METHODS: The level of cardiorespiratory fitness, BMI, percent body fat, waist circumference (WC), systolic blood pressure, glucose, triglycerides (TG), high-density lipoprotein-cholesterol (HDL-C), HOMA-IR, and hsCRP of 227 male high school students were measured. Analyses of multiple correlation and simple regression were applied. RESULTS: The results showed that the level of cardiorespiratory fitness correlated negatively with BMI, percent body fat, WC, TG, and HDL-C, in addition to HOMA-IR and hsCRP, and strongly influenced BMI, percent body fat, WC, TG, HDL-C, HOMA-IR, and hsCRP. Comparative analysis of our subjects showed that higher cardiorespiratory fitness levels had positive effects on BMI, metabolic syndrome risk factors, HOMA-IR, and hsCRP. CONCLUSIONS: This study found that there are close correlations between cardiorespiratory fitness and BMI, metabolic syndrome risk factors, HOMA-IR, and hsCRP. It also showed that, compared to lower levels of cardiorespiratory fitness, higher levels had beneficial effects on BMI, metabolic syndrome risk factors, diabetes, and cardiovascular disease risk factors.
Adipose Tissue
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Adolescent
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Blood Pressure
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Body Mass Index
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C-Reactive Protein
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Cardiovascular Diseases
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Glucose
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Homeostasis
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Humans
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Insulin
;
Korea
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Male
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Physical Fitness
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Risk Factors
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Triglycerides
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Waist Circumference
4.Re-evaluation of the indication for renal biopsy in childhood nephrotic syndrome.
Eun Kyoung SOHN ; Byung Soo CHO ; Chang Il AHN
Journal of the Korean Pediatric Society 1991;34(6):805-811
No abstract available.
Biopsy*
;
Nephrotic Syndrome*
5.A STUDY ON THE HEAT GENERATION OF BONE DRILLING BURS ACCORDING TO IRRIGATION DURING IMPLANTATION OF DENTAL IMPLANT.
Eun Soo MOON ; Heun Song LIM ; In Ho CHO
The Journal of Korean Academy of Prosthodontics 1999;37(4):433-453
There are a lot of elements affecting the success of implant prosthesis. The quality of surgical procedure is considered as one of the key factors. To avoid the excess heat generation is an important element of successful osseointegration and it can be achieved by using a gentle surgical technique with a sharp instrument in bone drilling. This study was performed to measure and analyze comparatively the heat transmitted to surrounding bone at a distance of 0.5mm from the periphery of the drill hole in each drilling stage. The results were as follows. In standard system, the temperature of surrounding bone tissue ranged from 29.2degrees Cto 48.3degrees C with irrigation and from 34.6degrees C to 84.3degrees C without irrigation. And in wide system, the temperature of surrounding bone tissue ranged from 29.5degrees C to 52.5degrees C with irrigation and from 34.8degrees C to 87.8degrees C without irrigation. And the temperature ranges exceeded the threshold without irrigation, while showing less than the threshold by the cooling effect of irrigation. In comparing standard system with wide system, although there was no significant difference, 4.3mm pilot and 4.3mm twist drill of wide system showed high value and wide system showed slightly high elevation of temperature in all depth in fixture installation In the finite element analysis, the calculated value by the Fourier's cooling law were applied to the bone drilling surface. And through analysis using different irrigation temperatures at 28degrees C, 15degrees C and 5degrees C, and according to the time. The result was that the cooling water at least below 15degrees C was required to maintain the temperature of surrounding bone less than threshold in bone drilling, the cooling water below 5degrees C was required to gain more sufficient cooling effect, and cooling over 5 seconds was needed after bone drilling for sufficient effect.
Bone and Bones
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Dental Implants*
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Finite Element Analysis
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Hot Temperature*
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Jurisprudence
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Osseointegration
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Prostheses and Implants
;
Water
6.The status and needs of rehabilitation of residencial stroke patients in a rural community.
Son Mi CHOI ; Yun Hee KIM ; Eun Soo CHO
Journal of the Korean Academy of Rehabilitation Medicine 1991;15(2):67-73
No abstract available.
Humans
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Rehabilitation*
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Rural Population*
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Stroke*
7.An Open-Label, Multicentre, Observational, Post-Marketing Study to Monitor the Safety and Effectiveness of Umeclidinium/Vilanterol in Korean Patients
Eun-Yeong CHO ; Jung-Eun CHO ; Eun-Bin LEE ; Seung Soo YOO ; Jung Hyun CHANG
Tuberculosis and Respiratory Diseases 2023;86(1):33-46
Background:
Umeclidinium/vilanterol (UMEC/VI; ANORO ELLIPTA, GSK) is a commonly used dual bronchodilator. This study evaluated the safety and effectiveness of UMEC/VI in Korean patients with chronic obstructive pulmonary disease (COPD) over a 6-year period.
Methods:
This was an open-label, multicentre, observational, post-marketing surveillance study. A total of 3,375 patients were enrolled consecutively in 52 hospitals, by 53 physicians, between July 2014 and July 2020. Patients who were administered UMEC/VI (fixed-dose 62.5 μg/25 μg) at least once and were monitored for safety and effectiveness were included in the analysis. Incidence and severity of adverse events (AEs) reported after administrating at least one dose of UMEC/VI were monitored, including unexpected adverse events (UAEs) and adverse drug reactions (ADRs). Effectiveness of UMEC/VI after 24 weeks of administration was also assessed using physician’s evaluation (effective, ineffectiveo change, worsening, indeterminable) and lung function improvement.
Results:
Of 3,375 patients, 3,086 were included in the safety assessment group (mean age±standard deviation: 69.76±8.80 years; 85.9% male [n=2,652]; 73.1% aged ≥65 years [n=2,255]). The overall incidence of AEs was 28.8% (n=890), of which 2.2% (n=67) were ADRs. Serious AEs and UAEs were reported in 181 (5.9%) and 665 (21.6%) patients, respectively, and two patients (<0.1%) reported unexpected severe ADR. Of the 903/3,086 patients analysed for effectiveness, most (82.8%, n=748) showed overall disease improvement after UMEC/VI treatment.
Conclusion
This study confirmed UMEC/VI administered to Korean patients according to the prescribing information was well-tolerated and can be considered an effective option for COPD treatment.
8.The Adequate Extent of Thoracic Sympathectomy for Essential Palmar Hyperhidrosis.
Young Sul YOON ; Young Soo KIM ; Yong Eun CHO ; Kyung Gi CHO
Journal of Korean Neurosurgical Society 1998;27(4):481-487
Essential palmar hyperhidrosis is a disease characterized by excessive perspiration on the palms and hands due to the hyperaction of sympathetic nervous discharge. In severe cases, excessive sweating is seen on the face, axilla, trunk, and soles. Several therapeutic modalities were applied but surgical resection of the sympathetic ganglion is the only curative method. Numerous open surgeries of the thoracic sympathetic ganglia for the treatment of palmar hyperhidrosis have been advocated, but they have also produced several complications. A new therapeutic technique for this disorder has been introduced by combining a thoracoscope and video system. Nowadays, thoracoscopic transthoracic sympathectomy is accepted as the treatment of choice for essential palmar hyperhidrosis. This technique is safe and easy. It also reduces the operating time and admission period. It has also very few complications. Compensatory hyperhidrosis on the trunk, back, and thigh, etc. is commonly an unwanted and unsolved complication after thoracic sympathectomy. Through my experience of thoracic sympathectomy, I thought that the incidence of compensatory hyperhidrosis was closely related to the extent of thoracic sympathectomy. So I restricted the extent of thoracic sympathectomy as a T2 sympathetic ganglion from September 1995. From Mar., 1989 To Aug., 1995, T2, T3 sympathetic ganglionectomies were performed for palmar hyperhidrosis patients and from Sept. 1995 T2 sympathetic ganglionectomies were performed. Using questionnaires, I compared these 2 groups. The results of this study are summarized as follows; 1) Using thoracoscopic transthoracic sympathectomy, operating time, admission period and complications could be reduced. 2) The risk of bleeding during the operation(especially bleeding from the hemiazygous vein) could be reduced in the T2 sympathectomy group. 3) The treatment effect of T2 sympathectomy is no different from T2, T3 sympathectomy for essential palmar hyperhidrosis. 4) The incidence of compensatory hyperhidrosis is less in the T2 sympathectomy group than in the T2, T3 sympathectomy group. From the above results, I concluded thoracoscopic transthoracic sympathectomy is the treatment of choice for essential palmar hyperhidrosis and the adequate extent for sympathectomy is T2 sympathetic ganglion.
Axilla
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Ganglia, Sympathetic
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Ganglionectomy
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Hand
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Hemorrhage
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Humans
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Hyperhidrosis*
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Incidence
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Surveys and Questionnaires
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Sweat
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Sweating
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Sympathectomy*
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Thigh
;
Thoracoscopes
10.Social adaptation in the Korean spinal cord injured patients.
Young Tae CHOI ; You Chul KIM ; Eun Soo CHO ; Soo Mi CHOI ; Yun Hee KIM
Journal of the Korean Academy of Rehabilitation Medicine 1992;16(4):473-481
No abstract available.
Humans
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Spinal Cord*