2.1H-Magnetic Resonance Spectroscopy in Prostatitis Syndrome.
Eun Sock LEE ; Duk Yoon KIM ; Jong Ki KIM
Korean Journal of Urology 2001;42(11):1163-1170
PURPOSE: To evaluate the specific metabolic patterns of the prostatic tissue with prostatitis syndrome 1H-magnetic resonance spectroscopy was performed on the patients with prostatitis syndrome. MATERIALS AND METHODS: Between 1996 and 2001, 24 men aged 19-59 (mean 36.9) were evaluated for the impression of prostatitis syndome. Image and spectrum were obtained with GE Signa 1.5T MRI/MRS unit using a GP flexible surface coils. Scout images were obtained at axial plane with T2-weighted fast spin echo sequence, and 1H spectra were acquired in the localized single-voxel elements of the prostatic tissue with stimulated echo-acquisition mode sequence before and after therapy. RESULTS: Elevated levels of amino acids and decreased citrate were detected in the prostatic tissue with prostatitis syndrome in comparison with normal tissue. Spectral variations of amino acids metabolic signal were found between different patient groups, and recovery of spectral pattern after 1 month or 3 months of antimicrobials therapy was found. In chronic noninflammatory pelvic pain syndrome, amino acids levels were elevated as in other prostatitis, but patterns were different. CONCLUSIONS: 1H-magnetic resonance spectroscopy using external body surface coil can be a useful and non-invasive method to evaluate and to monitor therapeutic efficacy of prostate diseases including the prostatitis syndrome.
Amino Acids
;
Citric Acid
;
Humans
;
Male
;
Pelvic Pain
;
Prostate
;
Prostatitis*
;
Spectrum Analysis*
3.A Prostate Carcinoma Metastasized to Bilateral Breasts.
Hyuk Jin CHO ; Eun Sock LEE ; Jae Shin PARK ; Jong Yup BAE ; Sung Hwan PARK
Korean Journal of Urology 2005;46(1):96-99
Antiandrogens are generally used for the treatment of prostate cancer, with gynecomastia the most common adverse event seen during therapy. However, a breast mass in a man with a carcinoma of the prostate may represent a metastatic disease or, less often, a primary carcinoma of the breast. Clinically diagnosed metastatic prostate cancer to the breast is a rare event. Breast metastasis represents an end-stage manifestation of the cancer, with an extremely poor prognosis. Herein, the case of a 62-year-old man, who presented with bilateral breast masses 7 months after antiandrogen therapy for the treatment of prostate cancer, is reported. An excisional biopsy of the breast mass revealed a metastatic prostatic adenocarcinoma.
Adenocarcinoma
;
Androgen Antagonists
;
Biopsy
;
Breast*
;
Gynecomastia
;
Humans
;
Male
;
Middle Aged
;
Neoplasm Metastasis
;
Prognosis
;
Prostate*
;
Prostatic Neoplasms
4.The Relationship between Obesity and the High Probability of Dementia Based on the Body Mass Index and Waist Circumference.
Won Sock CHANG ; Kon Hong WON ; Ju Yeon LEE ; Eun Tae KIM ; Hyuk Jung KWEON
Korean Journal of Family Medicine 2012;33(1):17-24
BACKGROUND: For an early detection and prevention of dementia, there are growing concerns about the high-risk group for dementia and mild cognitive impairment. With an increase of obesity and its complications, obesity has become a major public health problem. Therefore, the aim of this study was to investigate the relationship between obesity and the high probability of dementia. METHODS: This study was done with subjects aged 60 to 89 years who visited a health promotion center, from April 1, 2008 to April 30, 2008. A total of 293 subjects (164 males and 129 females) were included in the evaluation of cognitive function using the Korean version of the Seven Minutes Screen test. Logistic regression models were used to analyze the association between obesity and the high-risk group for dementia. RESULTS: Among a total of 293 subjects, 71 subjects (29 males and 42 females) had a high probability of dementia. When compared to normal body mass index (BMI) group, overweight and obesity groups had about a 2.2-fold and 2.4-fold higher probability of dementia (95% confidence interval [CI], 0.97 to 4.99 and 95% CI, 1.07 to 5.46, respectively). When compared to non-obese and non-abdominal obesity group, non-obese and abdominal obesity group and obese and abdominal obesity group had about a 1.5-fold and 2.0-fold higher probability of dementia (95% CI, 0.59 to 3.95 and 95% CI, 1.09 to 3.84, respectively). CONCLUSION: This study shows that as the BMI increased, subjects had a higher probability of dementia; additionally, it suggests that abdominal obesity could be related to a higher probability of dementia.
Aged
;
Body Mass Index
;
Dementia
;
Health Promotion
;
Humans
;
Logistic Models
;
Male
;
Mild Cognitive Impairment
;
Obesity
;
Obesity, Abdominal
;
Overweight
;
Public Health
;
Waist Circumference
5.A Case of Complete Female Urethral Loss with Vesicovaginal Fistula.
In Young CHUNG ; Chang Woo SEO ; Eun Sock LEE ; Dong Woo RO ; Duk Youn KIM ; Jae Shin PARK ; Kap Byung KIM
Korean Journal of Urology 1999;40(6):785-788
Complete urethral loss with vesicovaginal fistula is very infrequently encountered by the urologist. Urethral reconstruction may be accomplished with either bladder or vaginal wall flap. Moreover, it usually is necessary to reinforce the continence of reconstructed urethra with a well-vascularized pedicle flap from either the Martius labial flap, gracilis, perineum, or rectus. We report a case of the complete urethral loss with vesicovaginal fistula treated successfully with bilateral Martius labial fat graft.
Female*
;
Humans
;
Perineum
;
Transplants
;
Urethra
;
Urinary Bladder
;
Vesicovaginal Fistula*