Pathologists and others have been calling the serous cystadenoma of the pancreas "microcystic cystadenoma", following Compagno and Oertel's proposal in l978 because it usually consists of innumerable small cysts (less than 2cm). However, unilocular or predominantly macrocystic types of serous cystadenoma have been occasionally reported. Therefore, they present a difficulty in precise preoperative and intraoperative diagnosis for their simi1ar gross appearance to other cystic lesions of the pancreas. We discovered two cases of macrocystic and unilocular serous cystadenomas of the pancreas which were lined by cuboidal to flattened epithelial cells. They contained PAS positive and D-PAS negative intracytoplasmic glycogen granules. The unilocular, macrocystic and microcystic patterns may represent a morphologic spectrum of a pancreatic neoplasm. So we propose to use the term "serous cystadenoma" rather than microcystic cystadenoma.
Cysts

No abstract available.
Female ; Pregnancy ; Pregnancy, Ectopic*

No abstract available.
Twins, Conjoined*

PURPOSE: The purpose of this study was to investigate factors influencing college students' health promotion lifestyle. METHODS: The subject was 606 students. Statistical analysis with SPSS used descriptive statistics, t-test, one way ANOVA, Pearson correlation and Stepwise Multiple Regression. RESULTS: The average item score for health promotion lifestyle was 2.58. The subscale showing the highest score was interpersonal relationship (3.03), which was followed by spiritual growth (2.94), stress management (2.54), nutrition (2.52), physical activity (2.16) and health responsibility (2.15). There were significant differences according to age, gender, BMI, perceived health state, religion, economic state, live together, major and health promotion lifestyle. The most powerful predictors of health promotion lifestyle were the prior related behavior (51.8%) and self-efficacy (7.7%). The combination of prior related behavior, perceived self-efficacy, activity-related affect, social support, perceived stress, commitment to a plan of action accounted for 67.9% of the variance of health promotion lifestyle. CONCLUSION: Prior related behavior was the most powerful variable of health promotion lifestyle. Therefore, health promotion programs for changing and maintaining prior related behavior and increasing self-efficacy should be developed to promote a healthy lifestyle in college students.
Health Promotion* ; Humans ; Life Style* ; Motor Activity

Congenital chloride diarrhea (CLD) is an autosomal recessive disorder with the hallmark of persistent watery Cl(-)-rich diarrhea from birth. Mutations in the solute carrier family 26, member 3 (SLC26A3) gene, which encodes a coupled Cl-/HCO3- exchanger in the ileum and colon, are known to cause CLD. Although there are a few reports of CLD patients in Korea, none of these had been confirmed by genetic analysis. Here, we describe the case of a Korean infant with clinical features of CLD. Using direct sequencing analysis, we identified 2 sequence variants: a missense variant of unknown significance (c.525G>C; p.Arg175 Ser) and a splicing mutation (c.2063-1G>T) in the SLC26A3 gene; these had been inherited from the father and mother, respectively. Whilst CLD is rare, its main symptom, diarrhea, is very common in infants. Hence, the diagnosis of CLD can prove difficult. Mutational analysis of the SLC26A3 gene should be considered as a viable method to confirm a diagnosis of CLD in Korean infants with persistent diarrhea.
Asian Continental Ancestry Group/*genetics ; Chloride-Bicarbonate Antiporters/*genetics ; DNA Mutational Analysis ; Diarrhea/*congenital/diagnosis/genetics/radiography ; Heterozygote ; Humans ; Infant ; Male ; Metabolism, Inborn Errors/*diagnosis/genetics/radiography ; Mutation ; Mutation, Missense ; RNA Splicing ; Republic of Korea ; Ultrasonography, Prenatal

No abstract available.
Biopsy, Fine-Needle*

No abstract available.
Acoustic Stimulation* ; Acoustics* ; Female ; Fetal Heart* ; Fetus* ; Heart Rate, Fetal* ; Pregnancy

Fibrolamellar carcinoma (FLC) is a rare variant of hepatocellular carcinoma (HCC). A 26-year-old female presented a hepatic mass and mild elevation of liver enzymes. Viral markers were negative, and levels of tumor markers were normal. Radiologically, the mass was well demarcated with central dot-like calcification and hypervascularity. Under the diagnosis of hepatocellular carcinoma, right lobectomy was performed. The tumor was grayish yellow with central fibrosis and focal hemorrhage and invaded a septal bile duct. Non-neoplastic liver was unremarkable. Microscopically, the tumor consisted of large polygonal cells in sheets, cords, and pseudoglands that were interwound by dense collagenous stroma. Tumor cells had abundant deeply eosinophilic cytoplasm and large nuclei with prominent nucleoli. Intracellular bile pigments and pale bodies were present. Tumor cells were diffusely immunostained for cytokeratin 7 (CK7), but not for cytokeratin 20 (CK20). Strong expression of CK7 in the present case suggests dual differentiation of FLC.
Adult ; Bile Ducts ; Bile Pigments ; Biomarkers ; Carcinoma, Hepatocellular* ; Collagen ; Cytoplasm ; Diagnosis ; Eosinophils ; Female ; Fibrosis ; Hemorrhage ; Humans ; Keratin-20 ; Keratin-7* ; Keratins* ; Liver ; Biomarkers, Tumor

BACKGROUND: The aim of this study was to investigate the changes of body composition and muscle strength of North Korean refugees (NKRs) according to their duration of stay in South Korea. METHODS: NKRs who volunteered and were living in South Korea, aged 20 to 75 years were recruited. Body compositions were analyzed by bioelectrical impedance analysis. Muscle strength was measured with the hand grip test. Demographic and migration information was obtained with a questionnaire. RESULTS: A total of 158 volunteers were recruited at a mean age of 48.3+/-11.4 years. The mean time from when they escaped from North Korea and arrived in South Korea was 5.8+/-4.3 years. Height, weight, and body surface area were significantly smaller in all NKRs compared to South Korean controls, except for women aged over 50 years. In females of younger ages (<50 years), NKRs with more than a 4-year stay in South Korea had a higher weight and fat mass than that of those who had a shorter stay (less than 4 years) in South Korea. All NKRs had a weaker grip strength than that of the age-matched controls from South Korea. CONCLUSION: The NKRs showed relatively smaller physiques and weaker muscle strength than that of the South Korean controls. In younger female NKRs, shorter South Korean stay group showed small body weight and fat mass than that of longer South Korean stay group. Specific health support programs might be needed.
Body Composition* ; Body Surface Area ; Body Weight ; Democratic People's Republic of Korea ; Electric Impedance ; Female ; Hand ; Hand Strength ; Humans ; Korea ; Muscle Strength* ; Refugees* ; United Nations ; Volunteers

Partial trisomy 2p is a rare but relatively well-defined syndrome with distinctive clinical features, including marked psychomotor delay, dysmorphic face, and congenital heart disease. The phenotype of trisomy 18p is variable, from normal appearance to moderate mental retardation. Most cases of trisomy 2p and trisomy 18p result from the inheritance of an unbalanced segregant from a balanced parental translocation or due to de novo duplication. Here, we present the first report of a combined partial trisomy 2p and trisomy 18p due to a supernumerary marker chromosome (SMC). The final karyotype of the patient was 47,XX,+der(18)t(2;18)(p23.1;q11.1)[22]/46,XX[8]. The patient had typical dysmorphic features of partial trisomy 2p23-pter syndrome and congenital heart disease. SMCs are remarkably variable in euchromatic DNA content and mosaicism level. The precise identification of the origin and composition of SMCs is essential for genotype-phenotype correlation and genetic counseling.
Abnormalities, Multiple/*genetics ; Chromosomes, Human, Pair 18 ; Chromosomes, Human, Pair 2 ; Cytogenetic Analysis ; Female ; Genetic Counseling ; Heart Defects, Congenital/*genetics ; Humans ; In Situ Hybridization, Fluorescence ; Infant, Newborn ; Karyotyping ; Syndrome ; *Trisomy/diagnosis