OBJECTIVE: The purpose of this study is to analyze the present conditions of hypertensive diseases in pregnancy so as to examine the differences between the urban and rural communities in the southwest region of Chonnam about prenatal care from 1996 to 2000. METHODS: We analyzed the clinical characteristics of only 251 out of 13,296 pregnant women who were hospitalized to be delivered in Department of obstetrics and gynecology in the Mokpo Catholic Hospital for the past five years from 1996 to 2000. RESULTS: The incidence of hypertensive diseases in pregnancy was 1.89% of the total deliveries: mild preeclampsia (55.4%), severe preeclampsia (38.2%), eclampsia (1.2%) and chronic hypertension (5.2%). Hypertensive diseases in pregnancy was common in the age group of 25-29 years (45.9%) and in gestational age of 37-40 weeks was 67.3%. The rate of vaginal delivery was 49.0%: spontaneous delivery (33.5%), induced labor (15.5%) but the rate of cesarean section was 51%. As a maternal complications, anemia (55.7%) and postpartum hemorrhage (11.4%) were developed and fetus and neonatal complication due to intrauterine growth restriction showed a considerably high rate of 12.2%. Seen from the interrelation between a residential district and the frequency of prenatal care, 40.6% of pregnant women were undergone an prenatal care at most one time, especially 53.4% of reside in rural area (p<.05). The correlation between the frequency of prenatal care and the seriousness of an illness took up 52.1% of preeclampsia and 66.7% of eclampsia out of 102 women who were got the prenatal care at most one time. This is of great statistical significance (p<.05). The interrelation between the seriousness of an illness and residential district made little difference (p>.05). CONCLUSION: Not only a study of the cause and early diagnosis of hypertensive diseases in pregnancy, but also prenatal care, early checkup and education with keeping in close contact with an executive agency will lead to decrease newborn infant mortality and hypertensive diseases in pregnancy.
Anemia ; Cesarean Section ; Early Diagnosis ; Eclampsia ; Education ; Female ; Fetus ; Gestational Age ; Gynecology ; Humans ; Hypertension ; Incidence ; Infant, Newborn ; Jeollanam-do* ; Labor, Induced ; Mortality ; Obstetrics ; Postpartum Hemorrhage ; Pre-Eclampsia ; Pregnancy* ; Pregnant Women ; Prenatal Care ; Rural Population

OBJECTIVES: The present study was performed to evaluate whether naltrexone treatment are effectively lowering the urge of alcohol drinking, and to investigate the its mechanism of action. METHODS: 15 healthy male social drinkers were voluntarily participated. The experimental method was double-blind placebo-controlled cross over design. Subjects ingested a naltrexone (50mg)/day or placebo for 1 week. Plasma beta-endorphin, plasma ACTH and serum cortisol levels were measured before, at 20 minutes and at 60 minutes after alcohol exposure. Subjects completed self-report questionnaires such as the visual analog scales of drink urge and the alcohol sensation scales at regular intervals. RESULTS: 1) During naltrexone pretreatment period, subjects reported more headache, dizziness, nervousness, fatigue, day somnolence, nausea, and decreased appetite than placebo pretreatment period. But serum GOT/GPT levels were not significantly different between two pretreatment periods. 2) In case of naltrexone pretreatment, subjects reported significantly less urge to alcohol drink on the self-reporting urge scales, especially at post-drinking 20 minutes and 60 minutes than placebo pretreatment. 3) After alcohol challenge, subjects reported significantly more dizziness on the alcohol sensation scales in case of naltrexone pretreatment, and reported less mood elevation trend though it was not statistically significant. Other scores were not significantly different between two pretreatments. 4) Plasma beta-endorphin levels were significantly different when treated with naltrexone. In case of naltrexone-pretreatment, the increasing degree of plasma beta-endorphin during 20 minutes after alcohol challenge was significantly higher than placebo pretreatment. 5) Basal plasma ACTH level and basal serum cortisol level were not significantly different between two pretreatments. After alcohol challenge, only the decreasing degree of plasma ACTH levels during 20 minutes was significantly lowered in the naltrexone pretreatment than placebo pretreatment. CONCLUSIONS: Naltrexone reduced urge to alcohol drinking in social drinker. The action mechanism of naltrexone may be partially blocking opioid positive reward system and partially alcohol mimicking its property.
Adrenocorticotropic Hormone ; Alcohol Drinking ; Anxiety ; Appetite ; beta-Endorphin* ; Cross-Over Studies ; Dizziness ; Fatigue ; Headache ; Humans ; Hydrocortisone ; Male ; Naltrexone* ; Nausea ; Plasma* ; Surveys and Questionnaires ; Reward ; Sensation ; Visual Analog Scale ; Weights and Measures

OBJECTIVE: Arrhythmogenic right ventricular cardiomyopathy(ARVC) is a progressive cardiac muscle disease characterized as progressive fibrofatty replacement of the right ventricle, severe ventricular arrhythmia, and sudden death. However, there is no report of ARVC as a cause of sudden death in Korea. METHODS and RESULTS: Postmortem studies were done to 115 cases of sudden unexplained death at department of legal medicine, school of medicine, Kyungpook national university in year 1999. We identified 7 cases(6%) of typical ARVC with no other identifiable cause of sudden death. The subjects included 5 males and 2 females, ranging in age from 19 to 41 years (mean 29.7 years). All were found dead at bed (5 cases) or workshop (2 cases). Five cases were fibrofatty types and two cases were fatty types. Right ventricular aneurysm, inflammatory infiltrates and left ventricular involvement were found in 4, 2 and 1 cases, repectively. Two cases had family history of sudden death before age 40. No one was suspected of having cardiovascular disease or ARVC before death. CONCLUSION: These findings indicate that ARVC in Taegu-Kyungpook area may be more frequent than previously thought. ARVC may be a major cause of sudden unexplained death.
Aneurysm ; Arrhythmias, Cardiac ; Arrhythmogenic Right Ventricular Dysplasia* ; Cardiovascular Diseases ; Death, Sudden ; Education ; Female ; Forensic Medicine ; Gyeongsangbuk-do ; Heart Ventricles ; Humans ; Korea ; Male ; Myocardium

Peutz-Jeghers syndrome is a familial syndrome consisting of mucocutaneous pigmentation and gastrointestinal polyposis and appears to be inherited as a single pleiotropic autosomal dominant gene with variable and incomplete penetrance. Cases of hamartomatous polyps of the Peutz-Jeghers type without Peutz-Jeghers syndrome have only rarely been reported. Moreover, only one case of a Peutz-Jeghers polyp at the appendix has been reported; it was resected by appendectomy. We report here on a case of a 45 year old man who had a hamartomatous polyp of the Peutz-Jeghers type arising from the appendix. The polyp was successfully removed by endoscopic polypectomy. To our knowledge, this is the first case of a hamartomatous polyp of the Peutz-Jeghers type that originated from the appendix and that was resected endoscopically.
Appendectomy ; Appendix ; Genes, Dominant ; Penetrance ; Peutz-Jeghers Syndrome ; Pigmentation ; Polyps

BACKGROUNDS: The localization validity of interictal scalp EEG abnormalities in the patients with temporal lobe epilepsy(TLE) has been a subject of much debate. This study was an attempt to assess the general characteristics and the lateralization value of interictal scalp EEG abnormalities of TLE. We also examined the possible etiologic factors of bitemporal independent epileptiform discharges(BIED). METHODS: We investigated the interictal scalp EEGs of 59 patients. All patients have been seizure free but might have had persistent auras (Engel's classification, class I) after anterior temporal lobectomy(ATL) with minimum follow-up of 1 year. Long term scalp EEG monitoring records were evaluated for interictal EEG abnormalities in all patients. RESULTS: Scalp EEGs from 59 patients exhibited clear epileptiform discharges. Strictly unitemporal epileptiform discharge(UED) was present in 23 patients (39%). It was concordant with the side of seizure origin in 22 patients (95%), and discordant in 1 patient (5%). Thirty six patients (61%) had BIED. Twenty two patients with BIED showed lateralized preponderance which was defined as at least 80% laterality. It was concordant with the side of seizure origin in 21 patients (95%), and discordant in 1 patient (5%), and 14 patients were not lateralized. Bilateral synchronous epileptiform discharges were present in 4 patients (7%), and extratemporal spike in only 1 patient (2%). Localized temporal slow waves were shown in 33 patients (56%). It was concordant with the side of seizure origin in 28 patients, discordant in 1 patient. Four of 33 patients had bilateral temporal slow waves. There was no statistically significant difference in age at seizure onset, duration of epilepsy between the groups with UED and with BIED. Febrile seizures occurred similarly in both groups. CONCLUSIONS: It seems obvious that patients with UED or lateralized interictal temporal spike or sharp waves have a strong likelihood of ictal onset from the ipsilateral temporal region.
Classification ; Electroencephalography* ; Epilepsy ; Epilepsy, Temporal Lobe* ; Follow-Up Studies ; Humans ; Scalp* ; Seizures ; Seizures, Febrile ; Temporal Lobe*

No abstract available.
Hemangioma* ; Polyhydramnios*

This paper refers to the History on the Lecture of History of Medicine at Kyungpook National University School of Medicine since 1961 when assistant professor KIM Jyung-Myung, MD of Department of Clinical Pathology started this lecture of history of medicine to the freshman class to improve the medical morality among professors, students and physicians after the nation-wide 4 19 revolution against dictatorial government. At that time an immoral faculty and several government patronized faculties were expulsed by students on the above revolution. On the lecture dictation was used for the first time and merged to prints(KIM Jay-Sik, MD and KIM Jyung-Myung, MD), followed by published textbook(1979, revised on 1986) of Professor KIM Jyung-Myung. However our department faculties haven't entered the Korean Society for the History of Medicine until this time because of short of manpower and lack of the independent department(Department of History of Medicine). We are going to set up the Department at our Medical School in 1998 and to study about the improvement of medical education through the lecture of the history of medicine on the comparison of the current oriental and western medicine, and the unification of Korean medical system(modern medicine and Chinese medicine).

PURPOSE: On the basis of CT findings, to differentiate between solid ovarian tumor and uterine subserosalmyoma. MATERIALS AND METHODS: In eight surgically proven cases of solid ovarian tumor and in ten uterinesubserosal myoma patients, contrast-enhanced CT images were obtained. Two genitourinary radiologists reviewed thefindings with regard to degree of enhancement of the mass as compared with enhancement of uterine myometrium,thickening of round ligaments, visualization of normal ovaries, contour of the mass, and the presence of ascitesin the pelvic cavity. RESULTS: Six of eight ovarian tumors but only two of ten uterine myomas were less enhancedthan normal uterine myometrium (p <0.05). Pelvic ascites were seen in six of eight ovarian tumors, but in only oneof ten uterine myomas (p<0.05). Three of 16 ovaries in ovarian tumor patients, but 12 of 20 ovaries in uterinemyoma patients, were normal (p<0.05). Six of 16 round ligaments of the uterus in ovarian tumor patients, were thichened but 11 of 20 round ligaments in uterine myoma patients, were thickened (p>0.05). The contour of themass was lobulated in two of eight ovarian tumor patients, but in five of ten uterine myoma patients (p>0.05). CONCLUSION: CT findings suggestive of solid ovarian tumor were less contrast enhancement of the mass than ofnormal uterine myometrium, pelvic ascites, and nonvisualization of normal ovary.
Animals ; Ascites ; Female ; Humans ; Leiomyoma* ; Mice ; Myoma ; Myometrium ; Ovary ; Round Ligament of Uterus ; Round Ligaments ; Tomography, X-Ray Computed ; Uterus

Castleman's disease is a rare lymphoproliferative disorder of uncertain etiology which most commonly occurs in the mediastinum. We describe a case of a benign Castleman 's disease of the hyaline vascular type affecting the upper extremity, an extremely rare site of the disease.
Giant Lymph Node Hyperplasia* ; Hamartoma ; Hyalin ; Lymphoproliferative Disorders ; Mediastinum ; Upper Extremity*

OBJECTIVES: We surveyed the awareness and current status of using fumigant carbon disulfide for exterminate Curculio sikkimensis among chestnut farmers in Chungnam Province to suggest directions for health education and public relations. METHODS: We designed questionnaires to evaluate recognition of fumigant carbon disulfide. We conducted a questionnaire survey to assess recognition and recognition level of fumigant carbon disulfide by the study variables. RESULTS: The recognition status for fumigant carbon disulfide was 74.5%, but the recognition level was low (know well 27.5%). The path of recognition was 45.1% and 15.7% for neighbor and rural technology center, respectively. The recognition status for warning label of fumigant carbon disulfide was 52.9%. Recognition for warning label of fumigant carbon disulfide was tended to increase with high educational attainment, bigger owning land area. Recognition on the content of warning label were 29.4%, 27.5%, 21.6%, and 21.6% for inflammability, toxicity, hazard, and explosiveness, respectively. Using personal protection equipment was tended to increase with the high status of awareness on fumigant carbon disulfide. CONCLUSIONS: Health education programs for using fumigant carbon disulfide are needed for chestnut farmers. In addition, publicity information activities about prevention and protection of carbon disulfide poisoning are needed for high risk farmers.
Carbon Disulfide* ; Carbon* ; Chungcheongnam-do ; Farmers* ; Fumigation ; Health Education ; Humans ; Poisoning ; Public Relations ; Weevils*