1.A Statistical Study of Pediatric Dermatoses During Last 10 Years (1975 ~ 1984).
Yong Kee SEONG ; Seon Hoon KIM ; Hee Chul EUN ; Jai Il YOUN ; Yoo Shin LEE
Korean Journal of Dermatology 1986;24(2):196-204
11,609 of childhood new outpatients seen in Department of Dermatology of Seoul National University Hospital from 1975 to 1984 were analyzed statistica,lly. The study results were summarized as follows: l. 11, 609 out of 48, 188 new outpatients were under 15 years old age, amounting to 24. l %. 2. The 10 most common dermatoses were atopic dermatitis, vitiligo, urticari, hemangiorna, contact dermatitis, fungal disease, molluscum contagiosum, scabies, impetigo and nevocellular neuvs. The most freguent age groups were 2 to 6 years amounting to 47 2p, af total outpatients. 4. The peak incidence occurred in August, while the lowest incidence occurred in November and October. 5. Dermatoses which showed increasing tendency were nevocellular nevus and vitiligo, those of decreasing tendency were contact dermatitis and impetigo,
Adolescent
;
Dermatitis, Atopic
;
Dermatitis, Contact
;
Dermatology
;
Humans
;
Impetigo
;
Incidence
;
Molluscum Contagiosum
;
Nevus
;
Outpatients
;
Scabies
;
Seoul
;
Skin Diseases*
;
Statistics as Topic*
;
Vitiligo
2.Gender Difference in Self-Esteem of Medical Students.
Jeong seon YOO ; Won Sun YANG ; Kyong Eun LEE ; Sang Eun LEE ; Christopher Seongkyu LEE ; Hoo Yeon LEE ; Eun Cheol PARK
Korean Journal of Medical Education 2003;15(3):241-248
PURPOSE: Many studies from the past have indicated that women tend to have lower self- esteem than men. This cross-sectional study looks for this tendency in a medical school in Korea, where men are still thought to comprise much of a dominating force despite the current growth in number of female students in student body. Along with the cross-examination of possible gender difference in self-esteem, the significant and relevant factors will also be sought and discussed. METHODS: Questionnaires were obtained from 202 junior and senior students (125 male and 77 female students) in a medical school in Korea. Self-esteem was determined using the Rosenberg self-esteem scale (reliability = 86% in our study). Multiple regression analysis was used to determine gender difference in self-esteem and statistical relevance in each covariate. RESULTS: There was no statistically significant difference in self-esteem between male and female medical students. Significant factors related to self-esteem include school rank, physical attractiveness, and depression, among which of them, depression was the strongest. CONCLUSION: Innate limitation of cross-sectional studies and evaluation of selected junior and senior students of a single medical school could possibly explain for the absence of gender difference in self-esteem in this study. Academic achievement and physical attractiveness are shown to be positive factors for self-esteem, while depression puts negative force in one's self-esteem.
Cross-Sectional Studies
;
Depression
;
Female
;
Humans
;
Korea
;
Male
;
Schools, Medical
;
Students, Medical*
;
Surveys and Questionnaires
3.The Effect of Acute Normovolemic Hemodilution on Cardiopulmonary Bypass in Coronary Artery Bypass Grafting Surgery.
Jeong Seon HAN ; Eun Sook YOO ; Seok Whan YOON ; Sook Young LEE
Korean Journal of Anesthesiology 1999;37(3):406-411
BACKGROUND: Systemic arterial hypotension is relatively common following initiation of cardiopulmonary bypass (CPB). Decreased blood viscosity is induced by acute normovolemic hemodilution (ANH) and by the use of crystalloid oxygenator prime. The purpose of this paper is to study the effect of ANH on mean arterial pressure, perfusion flow index and PaO2/FiO2 upon initiation of CPB, and on homologous blood usage during CPB in coronary artery bypass grafting (CABG) surgery. METHODS: We reviewed 30 patients constituting an ANH group, and 30 patients in a control group who had undergone CABG surgery within the past 2 years. In the ANH group, 1 or 2 units of fresh autologous whole blood were sequestrated following induction of anesthesia. We compared mean arterial pressure, perfusion flow index, PaO2/FiO2, and hematocrit on the initiation of CPB, and homologous blood usage during and post CPB periods between the groups. RESULTS: Upon initiation of CPB, hematocrit in the ANH group was significantly less than in the control group, but there was no significant difference in mean arterial pressure, perfusion flow index or PaO2/FiO2 between the groups. The use of homologous blood during CPB in the ANH group was not significantly higher than in the control group. CONCLUSIONS: Acute intraoperative normovolemic hemodilution in CABG surgery was safely performed without significant hypotension and increased homologous blood usage during CPB.
Anesthesia
;
Arterial Pressure
;
Blood Viscosity
;
Cardiopulmonary Bypass*
;
Coronary Artery Bypass*
;
Coronary Vessels*
;
Hematocrit
;
Hemodilution*
;
Humans
;
Hypotension
;
Oxygen
;
Oxygenators
;
Perfusion
4.A Biomechanical Study on the Fixational Strength of the Trans-pedicular Screw: In vitro measurement
Myung Chul YOO ; Sang Eun LEE ; Ki Tack KIM ; Seung Deok SEON ; In Young KIM ; Mu Seong MOON
The Journal of the Korean Orthopaedic Association 1995;30(3):459-469
With porcine vertebrae, the static and dynamic holding power of the pedicle screws under various conditions were measured to understand the biomechanical nature of the transpedicular screw fixation in spine. The objectives of the present study were; (1) to find the correlation between the insertion depth of the screw and the resulting holding power, (2) to determine the effect of bone cement augmentation on the screw fixation in a loosened hole, and (3) to assess the load-sharing mechanism between the cortical and the cancellous one surrounding the screw in this fixational system. The geomorphological characteristics of each porcine vertebra was measured directly with a micro-caliper. The bone mineral density of the specimens was also measured. Material with screw was holded in the fixed cross head of material testing system(Autograph E-10T). Testing force was applied and graph was obtained in the chart record. The results of the static pull-out tests in this study showed that there was a statistically-significant positive correlation between the screw diameter and the pull-out resistance(p < 0.05). The strength of the fixation did not actually increase as much as the insertion depth of the screw increased in these tests(r=0.457). In low-cycle fatigue tests, the increased number of cycles was required to clinical failure in the deeper-inserted crews. Considering the mechanical failure, a statistically-significant positive correlation between the failure cycle and the insertion depth was observed in both deep and shallow insertion groups(p < 0.05). Nonpressurized PMMA augmentation appeared to restore the ability of the screws to withstand pullout loading of the original value. On the effect of the cortical and cancellous bone, the most important factor was the cortical bone of the entrance near the screw.
Bone Density
;
Fatigue
;
Head
;
In Vitro Techniques
;
Pedicle Screws
;
Polymethyl Methacrylate
;
Spine
5.Predictive costs in medical care for Koreans with metabolic syndrome from 2009 to 2013 based on the National Health Insurance claims dataset
Jeong Seon YOO ; Eun Yeong CHOE ; Yoo Mee KIM ; Se Hwa KIM ; Young Jun WON
The Korean Journal of Internal Medicine 2020;35(4):936-945
Background/Aims:
Although metabolic syndrome has been associated with increasing medical costs worldwide, there have been no studies using a nationwide and longitudinal South Korean dataset. We investigated trends in subsidized medical costs among Korean adults with metabolic syndrome.
Methods:
This study was based on the National Sample Cohort database of South Korea. We used data of national health checkups in 2009 as well as data of subsidized prescription drugs and the Korean Classification of Disease diagnosis codes from claims in 2007 to 2008 to identify underlying diseases. We calculated the direct medical costs, which were subsidized by the Korean National Health Insurance, among 204,768 individuals older than 20 years from 2009 to 2013.
Results:
The proportion of subjects with metabolic syndrome was 27.2%. Direct medical costs for 5 years differed by a magnitude of 2.16 between subjects with and without metabolic syndrome. The costs increased by approximately 41.8% in the metabolic syndrome group in 5 years. Direct medical costs increased with every additional risk factor, even if a subject had less than three risk factors of metabolic syndrome. Metabolic syndrome per se and all of its components, except low serum high-density lipoprotein cholesterol level, resulted in a significant increase in medical costs.
Conclusions
The medical costs of subjects with metabolic syndrome were higher than that of those without metabolic syndrome and it increased with the number of risk factors. Further research using cumulative data of more than 10 years, including unsubsidized and indirect costs, is needed in the future.
6.Changes of Lung Compliance and Gas Exchange after Modified Ultrafiltration in Pediatric Cardiac Surgery.
Eun Sook YOO ; Jeong Seon HAN ; Sang Kee MIN ; Sook Young LEE ; Myung Sin SEO ; Jin Su KIM
Korean Journal of Anesthesiology 1999;37(6):1015-1019
BACKGROUND: Pediatric cardiopulmonary bypass (CPB) often results in increased capillary permeability and accumulation of excess total body water, which can lead to multiple organ dysfunctions. Recently, modified ultrafiltration (MUF) has been used during pediatric cardiac surgery to limit various deleterious effects of CPB. We investigated the effects of MUF on lung compliance and gas exchange in pediatric open heart operations. METHODS: Fifteen pediatric open heart surgery patients were evaluated. Lung compliance (dynamic compliance), arterial oxygen tension (PaO2), arterial to end-tidal carbon dioxide tension difference (Pa-ETCO2), systolic blood pressure (SBP), heart rate, and hematocrit (Hct) were measured. Measurements were made after induction of anesthesia, after CPB, after MUF and after sternal closure. RESULTS: Lung compliance, PaO2, SBP and Hct increased significantly after MUF compared to after CPB. After sternal closure, lung compliance decreased significantly from the value following MUF. PaO2, SBP, Hct decreased significantly after CPB compared to the values obtained after induction of anesthesia. Pa-ETCO2 and heart rate did not change significantly. CONCLUSIONS: Modified ultrafiltration increases lung compliance, PaO2, SBP and Hct. MUF is an excellent option for improving cardiopulmonary function immediately following pediatric cardiopulmonary bypass.
Anesthesia
;
Blood Pressure
;
Body Water
;
Capillary Permeability
;
Carbon Dioxide
;
Cardiopulmonary Bypass
;
Heart
;
Heart Rate
;
Hematocrit
;
Humans
;
Lung Compliance*
;
Lung*
;
Oxygen
;
Thoracic Surgery*
;
Ultrafiltration*
7.Diurnal Rhythms of Serum Total Testosterone, Sex Hormone Binding Globulin, Estradiol and Luteinizing Hormone in Young Korean Men: a Circadian Study.
Dae Seon YOO ; Eun Tak KIM ; Kyung Yeun KIM ; Seung Hyo WOO
Korean Journal of Andrology 2007;25(2):60-67
PURPOSE: Currently, no studies have examined the diurnal variation of sex hormones in Korean men. We realized that accurate models of the diurnal variation of the sex hormones in Korean males are needed to evaluate and manage patients in urology. Therefore diurnal variation of testosterone and related sex hormones were investigated in young Korean men. MATERIALS AND METHODS: Healthy Korean men from 20 to 25 years old who had evident secondary growth were enrolled. We drew blood from each subject 12 times at 2-hour intervals for 24 hours. The concentrations of total testosterone, estradiol, luteinizing hormone, sex hormone binding globulin and albumin were measured. The free and bioavailable testosterone were calculated by Vermeulen's equation. To analyze the rhythmicity of diurnal variation in sex hormones, 24-hr cosine regression analysis was used for the statistical analysis. RESULTS: Total testosterone, free testosterone, estradiol, and testosterone estradiol ratio demonstrated a significant diurnal cosinor rhythm. The diurnal variation of bioavailable testosterone did not demonstrate a statistically significant cosinor rhythm. CONCLUSIONS: The diurnal variations of serum total and free testosterone concentration in Korean young men were similar to those found in studies of Caucasian men. Our study provides basic data for future studies of Korean male sex hormones. Furthermore, additional studies targeted toward various male age groups are needed to make the standard models of sex hormones in Korean men.
Adult
;
Circadian Rhythm*
;
Estradiol*
;
Gonadal Steroid Hormones
;
Humans
;
Lutein*
;
Luteinizing Hormone*
;
Male
;
Periodicity
;
Sex Hormone-Binding Globulin*
;
Testosterone*
;
Urology
8.The Influence of High- and Low-Dose Aprotinin on Thromboelastography in Coronary Artery Bypass Grafting Surgery.
Jeong Seon HAN ; Sung Mee JUNG ; Sook Young LEE ; Eun Sook YOO ; Chang Kuk SUH ; Sang Kee MIN
Korean Journal of Anesthesiology 2000;39(4):508-515
BACKGROUND: The protease inhibitor aprotinin reduces blood loss and homologous blood usage after a cardiac operation. The aim of the present study was to investigate the effect of low- and high-dose aprotinin on thromboelastography (TEG) variables and to examine the relationship between the clinical effect of aprotinin and the TEG variables in coronary artery bypass grafting surgery (CABG). METHODS: Twenty-three patients scheduled for an elective CABG were randomly assigned to receive either high does (group H, n = 12) or low does (group L, n = 11) aprotinin. TEG variables, and a coagulation profile test at baseline and arrival in ICU were performed. Amount of blood loss, homologous blood transfusion and heparin requirements were measured. RESULTS: In group L, there were significant increases in r time and k time and significant decreases in MA and alpha angle after aprotinin administration. In group H, just k time after aprotinin administration was significantly increased compared with baseline data. There were no significant differences in amount of blood loss and allogenic blood transfusions between the two groups. There was not a significant correlation between TEG variables and amount of blood loss in both groups. Interestingly a siginificant negative correlation between the length of cardiopulmonary bypass and MA was noted in group H (r = -0.63; P < 0.05). CONCLUSIONS: In CABG patients, aprotinin preserves platelet function more significantly in the high-dose aprotinin group. In addition, TEG variables indicated a later clot formation in the low dose aprotinin group.
Aprotinin*
;
Blood Platelets
;
Blood Transfusion
;
Cardiopulmonary Bypass
;
Coronary Artery Bypass*
;
Coronary Vessels*
;
Heparin
;
Humans
;
Protease Inhibitors
;
Thrombelastography*
9.The Size of the Main Pulmonary Artery in Patients with IPF: Relationship with the Extent of Honeycombing Lesion.
Jong Koo LEE ; Eun Joo YUN ; Jae Kook KO ; Hae Kyung CHUN ; Seon Young YOO ; Hyun Ja SHIN
Journal of the Korean Radiological Society 1996;35(4):487-491
PURPOSE: To predict pulmonary arterial hypertension by comparing the extent of honeycombing lesion with the diameter of main pulmonary artery (MPA). MATERIALS AND METHODS: We retrospectively reviewed 21 patients (20 men, one woman) who showed honeycombing lesion on HRCT, and also analysized a control group of 30 (29men, one woman) who had no cardiopulmonary symptom and no abnormality on chest CT. On Chest HRCT, we scanned at four levels [1)aortic arch, 2) bifurcation of bronchus, 3) mid-portion of left ventricle, 4) dome of right diaphragm], and two radiologists then evaluated the proportion of honeycombing lesion within the entire lung field. According to the extent of this, we divided the patients into five groups [<20% (I), 20-39% (II), 40-59% (III), 60-79% (IV), > or = 80% (V)], and then divided Group I into two subgroups [<10 % (I|1), 10-19% (I-2)]. Using contrast-enhanced routine CT, the main pulmonary artery (MPA) was measured at its the widest diameter perpendicular to the long axisat the level of its bifurcation. RESULT: In group I (n=11) MPA was 28.4+/-2.6mm ; in group II (n=6), it was31.7+/-2.0mm ; in group III (n=2), 33.5mm ; in group IV (n=1), 33mm ; and in group V (n = 1), 39mm. In subgroup I-1MPA was 26.1+/-1.9mm, and in subgroup I-2, it was 29.8+/-1.6mm. In the control group, MPA was 25.1+/- 2.0mm. CONCLUSION: The extent of honeycombing lesion is closely related to the change in diameter of the MPA. Honeycombing lesion extending over more than 10% of the lung field may lead to pulmonary arterial hypertension.
Bronchi
;
Heart Ventricles
;
Humans
;
Hypertension
;
Hypertension, Pulmonary
;
Lung
;
Pulmonary Artery*
;
Retrospective Studies
;
Thorax
;
Tomography, X-Ray Computed
10.Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology Diagnosis of Solid Pseudopapillary Neoplasm: Three Case Reports with Review of Literature.
Joon Seon SONG ; Chong Woo YOO ; Youngmee KWON ; Eun Kyung HONG
Korean Journal of Pathology 2012;46(4):399-406
Solid pseudopapillary neoplasm of the pancreas (SPN) is relatively rare and it occurs almost exclusively in women. We recently experienced three cases of SPN diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). These three cases were two male and one female patient whose age was 29, 37, and 44 years old. Radiological diagnosis was pancreatic endocrine tumor (PEN) showing solid with a heterogenous echogenicity. EUS-FNA cytology specimens consisted of single cells and aggregates of uniform cells, forming microadenoid structures, branching, papillary clusters with delicate fibrovascular cores. In conclusion, a single diagnosis of SPN based on clinical and radiological findings would be risky because there is a possibility of it being misdiagnosed as PEN or other malignancies. An EUS-FNA is therefore essential for establishing the diagnosis. In addition, the pathologists should recognize the characteristic cytologic findings with immunoprofiles of SPN to prevent misdiagnosis of SPN.
Biopsy, Fine-Needle
;
Diagnostic Errors
;
Endoscopic Ultrasound-Guided Fine Needle Aspiration
;
Female
;
Humans
;
Male
;
Pancreas