1.A study on hepatitis C virus antibody (anti-HCV) in healthy blooddonors and patients with type B and NANB hepatitia and chronicliver disease.
Jeong Nyeo LEE ; Eun Joo HWANG ; Jong Rae JO ; Kun Ju HAHM ; Eun Yup LEE ; Han Chul SON ; Soon Ho KIM
Korean Journal of Clinical Pathology 1991;11(1):207-214
No abstract available.
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Humans
2.Clinical survey of 8 cases of endodermal sinus tumor.
Kwang Soon AHN ; Rae Ok PARK ; Jung Il CHA ; Byung Hun JUNG ; Jin Woo KIM ; Se Il KIM ; Sung Eun NAMKOONG ; Seung Jo KIM
Korean Journal of Obstetrics and Gynecology 1992;35(1):68-76
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
3.Acute Marchiafava-Bignami Disease With Typical White Matter Involvement on Diffusion Weighted MRI.
Hey Eun SHIN ; Jae Guk KIM ; Seong Rae JO ; Seong Hae JEONG ; Soo Jin YOON
Journal of the Korean Neurological Association 2008;26(4):376-378
Marchiafava-Bignami disease (MBD) is characterized by cerebral white matter lesions associated with chronic alcoholism. Premortem diagnosis of MBD is usually based on history and clinical manifestations. We report a case of acute MBD in which diffusion-weighted MRI (DWI) showed high signal intensities along the white matter including the corpus callosum. DWI may be useful in premortem diagnosis of acute MBD.
Alcoholism
;
Corpus Callosum
;
Diffusion
;
Diffusion Magnetic Resonance Imaging
;
Humans
;
Leukoencephalopathies
;
Marchiafava-Bignami Disease
4.Dismembered Corpse : medicolegal implications.
Young Shik CHOI ; Sang Yong LEE ; Yu Hoon KIM ; Gap Rae JO ; Bong Woo LEE ; Kyung Moo YANG ; Nak Eun CHUNG ; Joong Seok SEO ; Han Young LEE ; Won Tae LEE ; Hyun Wook KANG
Korean Journal of Legal Medicine 2000;24(2):15-27
Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.
Autopsy
;
Cadaver*
;
Criminals
;
Hemorrhage
;
Homicide
;
Humans
;
Joints
5.A Case of Lipoid Pneumonia after Ingestion of Green Perilla Oil.
Kwang Jin JEONG ; Yong Eun KIM ; Gueon Jo LIM ; Kyong Duk SUH ; Jin Do KIM ; Ju Hong LEE ; Dae Young KOO ; IL Sun LEE
Tuberculosis and Respiratory Diseases 1999;47(1):123-126
We report a case of lipoid pneumo nia in a 57-year-old man who had a history of ingestion of green perilla oil and residual neurologic deficit of cerebral infarction with right hemiparesis. Lipoid pneumonia was diagnosed by bronchoalveolar lavage.
Bronchoalveolar Lavage
;
Cerebral Infarction
;
Eating*
;
Humans
;
Middle Aged
;
Neurologic Manifestations
;
Paresis
;
Perilla*
;
Pneumonia*
6.A case of Thrombotic thrombocytopenic purpura - hemolytic uremic syndrome presenting with cortical blindness confirmed by MRI.
Gueon Jo LIM ; Yong Eun KIM ; Kyong Duk SUH ; Yu Seong JEONG ; Jin Do KIM ; Ju Hong LEE ; Dae Young KOO ; Tae Yoon LEE ; Yong Hun SIN ; Yong Ki PARK
Korean Journal of Medicine 1999;56(1):119-123
Thrombotic thrombocytopenic purpura (TTP) and the related hemolytic uremic syndrome (HUS) are disorders characterized by thrombocytopenia, microangiopathic hemolytic anemia, a variable degree of impairment of renal function and fluctuating neurological symptoms, which are thought to be due to platelet activation and subsequent formation of thrombi in the microcirculation. The fact that there was no clear-cut clinical and laboratory features that differentiate HUS from TTP has lead to view these two syndromes as a clinical continuum. Microvascular thrombosis is the typical lesion and closely related with endothelial injury and platelet activation. Pathologic alterations of the brain parenchyma are mainly manifested by small multiple infarcts. Numerous cases of CNS complications of these syndromes have been evaluated by using CT, but few reports have mentioned the MR findings. We experienced a case of TTP-HUS that had clinical features of cortical blindness and the brain lesion was confirmed by MRI showing cerebral infarct at the occipital area but it was reversible course. So we report this case with a brief review of literature.
Anemia, Hemolytic
;
Blindness, Cortical*
;
Brain
;
Hemolytic-Uremic Syndrome*
;
Magnetic Resonance Imaging*
;
Microcirculation
;
Platelet Activation
;
Purpura, Thrombotic Thrombocytopenic*
;
Thrombocytopenia
;
Thrombosis
7.The Significance of Mucosal Biopsy in Normal Colonoscopy.
Jae Seon KIM ; Eun Rae JO ; So Young KWON ; Kwan Soo BYUN ; Young Tae BAK ; Jin Ho KIM ; Jong Guk KIM ; Chang Hong LEE ; Chul Hwan KIM ; Nam Hee WON
Korean Journal of Gastrointestinal Endoscopy 1993;13(4):713-718
Many patients of gastroenterology clinics complain symptoms requiring colonic investigations. Radiological examinations may fail to detect early inflammatory bowel diseases and small neoplasms or polyps. And therefore colonoscopies are performed in preference to barium enema. Recently several reports raised a question regarding whether biopsy is necessary in a macroscopically normal colon. To determine what proportion of apparently normal colons is histologically abnormal, to measure the thickness of subepithelial basement membrane(SEBM) in normal colons, and to see whether the thiekness varies according to the different areas of the large bowel we prospectively analyzed 100 consecutive subjects with normal laboratory findings and normal mucosa on colonoscopy. Significant histologic abnormalities were not detected in all 100 cases. Thickness of SEBM (mean+SD) was 1.6+0.4 um at hepatic flexure, 1.6+0.4um at splenic flexure and 1.7+0.4 pm at sigmoid colon. The SEBM was significantly thicker at the sigmoid colon than at the hepatic flexure. Range of thickness of normal SEBM was 0.8 to 2.5 pm(mean+2SD). Maximum thickness of SEBM was 3 pm. The result of this study suggests that doing colonoscopic biopsies in all normal colons do not seem to be essential in Koreans yet.
Barium
;
Biopsy*
;
Colon
;
Colon, Sigmoid
;
Colon, Transverse
;
Colonoscopy*
;
Enema
;
Gastroenterology
;
Humans
;
Inflammatory Bowel Diseases
;
Mucous Membrane
;
Polyps
;
Prospective Studies
8.Regulation of Host Cell Signaling Pathways by Respiratory Syncytial Virus Nonstructural Protein NS1 and NS2.
Han Bo SHIN ; Myung Soo CHOI ; Chae Min YI ; Ji Eun KIM ; Su Ji JO ; Hye In KIM ; Na Rae LEE ; Kyung Soo INN
Journal of Bacteriology and Virology 2014;44(3):283-289
Human Respiratory Syncytial virus (hRSV) is a leading cause of severe lower respiratory tract diseases in the pediatric population.hRSV frequently causes severe morbidity and mortality in high risk groups including infants with congenital heart disease and the immunosuppressed patients. Although hRSV is recognized as a major public health threat and economic burden worldwide, there is no licensed vaccine and effective therapeutic agent. Viral nonstructural (NS) proteins have been known to play multiple functions for efficient viral replication and pathogenesis. Especially, diverse functions of influenza A virus NS1 have been extensively studies. Recent studies demonstrated that NS1 and NS2 of RSV also exert diverse functions to modulate cellular environment and antiviral immune responses. Since NS proteins of RSV are required for efficient replication and pathogenesis, NS mutant viruses have been tested as live-attenuated vaccines. This review will outline the recent progress in understanding the various functions of RSV NS1 and NS2.
Heart Defects, Congenital
;
Humans
;
Infant
;
Influenza A virus
;
Interferons
;
Mortality
;
Public Health
;
Respiratory Syncytial Virus, Human
;
Respiratory Syncytial Viruses*
;
Respiratory Tract Diseases
;
Vaccines
9.A Peculiar Type of Anomalous Pancreaticobiliary Ductal Union.
Yong Eun KIM ; Geoun Jo LIM ; Kyong Duk SUH ; Kwang Jin JEONG ; Jin Do KIM ; Ju Hong LEE ; Dae Young KOO
Korean Journal of Gastrointestinal Endoscopy 2000;20(2):145-148
Anomalous pancreaticobiliary ductal union (APBDU) is an uncommon anomaly, defined as the junction between the common bile duct and the pancreatic duct outside the duodenal wall and beyond the influence of the sphincter of Oddi. This anomaly, which has been recognized frequently since the introduction of ERCP, is believed to be associated with biliary tract lesions such as congenital biliary dilatation, biliary tract carcinoma, and pancreatic lesions such as pancreatitis new paragraph. A 28-year-old male was admitted due to sudden abdominal pain and vomiting. An ERCP revealed a peculiar type of APBDU; the duct of Wirsung and CBD fused and formed a long common channel before entering the major papilla, and the duct of Santorini connected to the duct of Wirsung is patent. So, when contrast dye was inserted into the minor papilla, both the CBD and the duct of Wirsung were made visible. This case of the peculiar type of APBDU which showed characteristic ERCP findings are herein reported.
Abdominal Pain
;
Adult
;
Biliary Tract
;
Cholangiopancreatography, Endoscopic Retrograde
;
Common Bile Duct
;
Dilatation
;
Humans
;
Male
;
Pancreatic Ducts
;
Pancreatitis
;
Sphincter of Oddi
;
Vomiting
10.A Case of Tuberculous Lymphadenitis Causing Obstructive Jaundice.
Chang Hong LEE ; Jae Seon KIM ; Goo LEE ; Young Tae BAK ; Jin Ho KIM ; Jong Guk KIM ; Nam Hee WON ; Eun Rae JO ; Sung Joon LEE ; Hong Young MOON
Korean Journal of Gastrointestinal Endoscopy 1994;14(1):115-120
Obstructive disorders of the biliary trees include occlusions of the bile duct lumen by stones, intrinsic disorders of the bile ducts, and extrinsic compressions. The most common biliary cause of obstructive jaundice is the presence of stones. Intrinsic disorders of the bile ducts may be inflammatory, infectious, or neoplastic. And significant enlargement of adjacent lymph nodes due to metastatic tumors or lymphoma can occasionally obstruct the extrahepatic bile ducts. But obstructive jaundice produced by periportal tuberculous lymphadenitis with no evidence of pulmonary tuberculosis is very rare. We report a case of tuberculous lymphadenitis causing obstructive jaundice with a mass around mid common bile duct on abdominal sonogram, CT scan and ERCP, and it was confirmed by an exploratory laparotomy.
Bile Ducts
;
Bile Ducts, Extrahepatic
;
Cholangiopancreatography, Endoscopic Retrograde
;
Common Bile Duct
;
Jaundice, Obstructive*
;
Laparotomy
;
Lymph Nodes
;
Lymphoma
;
Tomography, X-Ray Computed
;
Tuberculosis, Lymph Node*
;
Tuberculosis, Pulmonary