1.Preperative evaluation of the mandible in patients with carcinoma of the oral cavity and tonsils.
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):972-976
No abstract available.
Humans
;
Mandible*
;
Mouth*
;
Palatine Tonsil*
2.Surgical treatment of the anterior skull base tumor.
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):1018-1025
No abstract available.
Skull Base*
;
Skull*
3.Risk factors of recurrent spontaneous pneumothorax.
Eun Pyo HONG ; Yee Tae PARK ; Sung Sae HAN
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(5):533-540
No abstract available.
Pneumothorax*
;
Risk Factors*
4.A Case of Giant Cell Tumor of the Tendon Sheath Developing on the Dorsum of the Foot.
Ho Pyo LEE ; Hong Jin PARK ; Yeon Ho PARK ; Jin Wou KIM ; Eun Joo SUH
Korean Journal of Dermatology 1995;33(6):1168-1171
We report a case of giant cell tumor of the tendon sheath involving the foot, in a 21-year-old female patient, who presented with an asymptomatic tumor on the dorsum of her right foot. Histopathologically the tumor is surrounded by thin fibrous connective tissue. The characteristic findings of the excised specimen revealed a typical mixture of abundunt round or polygonal histocyte-like cells with varying portions of spindle-shaped fibroblast-like cells and multinucleated giant cells. Variable amounts of hyalinized fibrous stromal tissue were also present. After excision, local recurrence has not been observed for 3 months.
Connective Tissue
;
Female
;
Foot*
;
Giant Cell Tumors*
;
Giant Cells*
;
Humans
;
Hyalin
;
Recurrence
;
Tendons*
;
Young Adult
5.Congenital cystic adenomatoid malformation(type II)of lung: A case report.
Eun Pyo HONG ; Dong Hyup LEE ; Jung Cheol LEE ; Sung Dae HAN
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(8):650-653
No abstract available.
Lung*
6.Surgical treatment of coarctation of aorta less than 2 years old.
Eun Pyo HONG ; Dong Hyup LEE ; Jung Cheol LEE ; Sung Sae HAN
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(8):604-608
No abstract available.
Aortic Coarctation*
;
Child, Preschool*
;
Humans
7.Sample Size and Statistical Power Calculation in Genetic Association Studies.
Genomics & Informatics 2012;10(2):117-122
A sample size with sufficient statistical power is critical to the success of genetic association studies to detect causal genes of human complex diseases. Genome-wide association studies require much larger sample sizes to achieve an adequate statistical power. We estimated the statistical power with increasing numbers of markers analyzed and compared the sample sizes that were required in case-control studies and case-parent studies. We computed the effective sample size and statistical power using Genetic Power Calculator. An analysis using a larger number of markers requires a larger sample size. Testing a single-nucleotide polymorphism (SNP) marker requires 248 cases, while testing 500,000 SNPs and 1 million markers requires 1,206 cases and 1,255 cases, respectively, under the assumption of an odds ratio of 2, 5% disease prevalence, 5% minor allele frequency, complete linkage disequilibrium (LD), 1:1 case/control ratio, and a 5% error rate in an allelic test. Under a dominant model, a smaller sample size is required to achieve 80% power than other genetic models. We found that a much lower sample size was required with a strong effect size, common SNP, and increased LD. In addition, studying a common disease in a case-control study of a 1:4 case-control ratio is one way to achieve higher statistical power. We also found that case-parent studies require more samples than case-control studies. Although we have not covered all plausible cases in study design, the estimates of sample size and statistical power computed under various assumptions in this study may be useful to determine the sample size in designing a population-based genetic association study.
Case-Control Studies
;
Gene Frequency
;
Genetic Association Studies
;
Genome-Wide Association Study
;
Humans
;
Linkage Disequilibrium
;
Models, Genetic
;
Odds Ratio
;
Polymorphism, Single Nucleotide
;
Prevalence
;
Sample Size
8.Reduction of Zygomatic Fractures Using the Carroll-Girard T-bar Screw.
Ji Eun BAEK ; Chan Min CHUNG ; In Pyo HONG
Archives of Plastic Surgery 2012;39(5):556-560
Zygomatic fractures are the second most common facial bone fractures encountered and treated by plastic surgeons. Stable fixation of fractured fragments after adequate exposure is critical for ensuring three-dimensional anatomic reduction. Between January 2008 and December 2010, 17 patients with zygomatic fractures were admitted to our hospital; there were 15 male and 2 female patients. The average age of the patients was 41 years (range, 19 to 75 years). We exposed the inferior orbital rim and zygomatic complex through a lateral brow, intraoral, and subciliary incisions, which allowed for visualization of the bone, and then the fractured parts were corrected using the Carroll-Girard T-bar screw. Postoperative complications such as malar asymmetry, diplopia, enophthalmos, and postoperative infection were not observed. Lower eyelid retraction and temporary ectropion occurred in 1 of the 17 patients. Functional and cosmetic results were excellent in nearly all of the cases. In this report, we describe using the Carroll-Girard T-bar screw for the reduction of zygomatic fractures. Because this instrument is easy to use and can rotate to any direction and vector, it can be used to correct displaced zygomatic bone more accurately and safely than other devices, without leaving facial scars.
Cicatrix
;
Cosmetics
;
Diplopia
;
Ectropion
;
Enophthalmos
;
Equipment and Supplies
;
Eyelids
;
Facial Bones
;
Female
;
Humans
;
Male
;
Orbit
;
Postoperative Complications
;
Reconstructive Surgical Procedures
;
Zygomatic Fractures
9.Primary carcinoid tumor of the larynx.
Kwang Moon KIM ; Eun Chang CHOI ; Won Pyo HONG ; Hyeon Joo JEONG
Yonsei Medical Journal 1989;30(2):193-197
A case of laryngeal carcinoid in a 54-year-old Korean female is reported and discussed. This tumor is extremely rare in the larynx and there have been just over twenty cases reported in the literature to date. The case showed an initial histologic finding of epithelial dysplasia and was finally confirmed to be a carcinoid tumor. Laryngeal carcinoids are often atypical histologically and may be misdiagnosed as undifferentiated carcinoma. An electron microscopic study revealed neurosecretory-type granules. Although the patient underwent a total laryngectomy and radical neck dissection, multiple hepatic metastasis was noted postoperatively.
Carcinoid Tumor/diagnosis/*pathology
;
Case Report
;
Female
;
Human
;
Laryngeal Neoplasms/diagnosis/*pathology
;
Middle Age
10.Multiple Primary Malignant Tumors: 39 cases.
Sun Young KIM ; Sang Pyo KIM ; Jong Min CHAE ; Sang Sook LEE ; Eun Sook CHANG ; Chai Hong CHUNG
Korean Journal of Pathology 1987;21(2):67-74
Thirty nine cases of multiple primary malignant tumors examined at the Department of Pathology, Keimyung University School of Medicine during the period from November 1974 through March 1986 were analysed clinicopathologically. The findings are as follows: 1) Thirty nine cases had synchronous lesion and six cases metachronous lesion. The second primary malignancy occurred mean 4.7 years after the first malignancy in patients with metachronous lesion. 2) The age at diagnosis of the first malignancy ranged from 26 to 76 years, the average being 51.8 years. The male-female ratio was slightly less than 1:1.2. 3) The most commonly involved site in multicentric origin was gastrointestinal tract (44.4%) with all adenocarcinoma and the second urogenital system (29.6%). In cases of different tissues or organs (11 cases), ovary was the most frequent site (5 cases), followed by cervix (4 cases). 4) Multiple primary malignant tumors of urogenital system were all eight cases and six cases among them (75%) had smoking and drinking habits. 5) The detailed informations about possible environmental, familial and host factors necessary for the investigation of multiple primary tumors were lacking in most cases. Therefore, the history taking with special attention to these factors must be carefully recorded. And also, we suggest that in the high-risk individuals, careful follow-up and thorough search for early cancer detection or prevention should be taken.
Female
;
Male
;
Humans
;
Adenocarcinoma