No abstract available.
Matrix Metalloproteinase 9

OBJECTIVES: The dysfunctional neural networks underlying self-evaluation in schizophrenia are overlapped with the neural structures involved in emotion regulation. The purpose of this study was to investigate the influence of anhedonia on the self-evaluation attitude of patients with schizophrenia. METHODS: Twenty healthy controls and twenty patients with schizophrenia performed a self-evaluation task, presenting a pair of the face (self, familiar other, and unfamiliar other) and word (negative, neutral, and positive noun) at the same time. Participants were asked to evaluate relevance between the pairs by pressing a corresponding button. Relevance rating scores were compared between the groups and were correlated with the severity of physical and social anhedonia. RESULTS: Patients evaluated the condition of a self face with a negative word and a familiar face with a negative word to be more relevant than healthy controls. In the patient group, the scores of relevance rating in the condition of an unfamiliar other face with a negative word were positively correlated with the anhedonia scale scores (physical : r=0.486, p=0.030 ; social : r=0.499, p=0.025). There was no correlation between the self-evaluation attitude and the severity of anhedonia. CONCLUSION: Patients with schizophrenia evaluate themselves badly in only negative circumstances, and anhedonia is not related to self-evaluation, but rather other-evaluation.
Anhedonia* ; Diagnostic Self Evaluation ; Humans ; Schizophrenia*

No abstract available.

BACKGROUND: To identify the prevalence and related factors for vitamin D deficiency in the patients who admitted to the medical intensive care unit (ICU) of a Korean tertiary care hospital. METHODS: We retrospectively analyzed the data from ICU patients requiring mechanical ventilation (MV) for a period of > 48 h to identify the prevalence and associated factors for vitamin D deficiency. Vitamin D deficiency was defined as serum 25-hydroxyvitamin D [25(OH)D] level < 20 ng/mL. RESULTS: Among 570 patients admitted to the ICU, 221 were enrolled in the study, 194 in the vitamin D deficient group and 27 in the non-deficient group. Prevalence of vitamin D deficiency in critically ill patients was 87.8%. The patient age was lower in the vitamin D deficient group compared with the non-deficient group (64.4 ± 15.4 vs. 71.0 ± 9.6 years, p = 0.049). A higher acute physiology and chronic health evaluation II (APACHE II) score (odds ratio [OR] 1.23, 95% confidence interval [CI] 1.10-1.37) and chronic illness (OR 3.12, 95% CI 1.08-9.01) were associated with vitamin D deficiency after adjusting for age and body mass index. Clinical outcomes of duration of MV, ICU stay, and 28- and 90-day mortality rates were not significantly different between the vitamin D deficient and nondeficient groups. CONCLUSIONS: Vitamin D deficiency was common in critically ill patients, particularly among younger patients. Higher APACHE II score and chronic illness were associated with vitamin D deficiency.
APACHE ; Body Mass Index ; Calcitriol ; Chronic Disease ; Critical Care ; Critical Illness* ; Humans ; Intensive Care Units ; Mortality ; Prevalence* ; Respiration, Artificial ; Retrospective Studies ; Tertiary Healthcare ; Vitamin D Deficiency* ; Vitamin D* ; Vitamins*

Purpose: : This study aimed to identify the factors influencing physical restraint-related practice among nurses working in the intensive care unit (ICU). Methods: : The participants consisted of 169 ICU nurses in three general hospitals in B and U cities. Data were collected from December 2021 to January 2022 through a structured selfadministered questionnaire. Demographic characteristics, physical restraint-related practice, Person-centered Critical Care Nursing (PCCN), work environment, and attitudes toward physical restraint use were measured. For data analyses, hierarchical multiple regressions were conducted using SPSS/WIN 25.0. Results: : Clinical careers in the ICU, better work environments, higher PCCN levels, and more positive attitudes toward physical restraint use were associated with a better practice of physical restraints, which together explained 35.5% of the total variance of the outcome. Conclusion : Our findings suggest that to promote a safe physical restraintrelated practice among ICU nurses, it is important to improve the nursing environment, prepare guidelines for applying PCCN, and provide education for endorsing positive attitudes toward the use of physical restraints.

No abstract available.
Gonadal Dysgenesis, Mixed*

Woolf syndrome is characterized by piebaldism and congenital deafness. Facial features of Waardenburg syndrome are absent and the parents and siblings are unaffected. We report herein a case of Woolf syndrome in 21-year-old male patient who has deafness of the righr ear and hypopigmented patches of whole body since birth. This pigmentary disorder may associate with other systemic abnormalities, we suggest this syndrome belongs to the spectrum of developmental abnormalities.
Deafness* ; Ear ; Humans ; Male ; Parents ; Parturition ; Piebaldism* ; Siblings ; Waardenburg Syndrome ; Young Adult

Woolf syndrome is characterized by piebaldism and congenital deafness. Facial features of Waardenburg syndrome are absent and the parents and siblings are unaffected. We report herein a case of Woolf syndrome in 21-year-old male patient who has deafness of the righr ear and hypopigmented patches of whole body since birth. This pigmentary disorder may associate with other systemic abnormalities, we suggest this syndrome belongs to the spectrum of developmental abnormalities.
Deafness* ; Ear ; Humans ; Male ; Parents ; Parturition ; Piebaldism* ; Siblings ; Waardenburg Syndrome ; Young Adult

No abstract available.
Biopsy*

No abstract available.
Intellectual Disability ; Walker-Warburg Syndrome*