1.Airway Resistance after Exercise Loading Test in Asthmatic Children.
Ji Eun LEE ; Young Mi HONG ; Kyung Hee KIM
Journal of the Korean Pediatric Society 1994;37(10):1333-1339
Exercise induced asthma (EIA) is defined as acute, reversible, usually self-limiting airway obstruction which develop after strenous exercise in patients with asthma. EIA is a bigger problem in children than adults due to more active and smaller airways which obstruct more easily when bronchospasm develops. The exercise elicited many change in pulmonary function of asthmatic children. These change could be measured by measurements of PEFR, FEV1, FVC, or SRaw. The propose of this study is to determine the changes and sensitivity of different pulmonary function test in asthmatic children. 37 asthmatic children exercised on free running and pulmonary function tests were performed before and every 5 minutes during 15 minutes after exercise. The results were as follows. 1) In 37 asthmatic children, EIA developed in 23 children (62%) and did not developed in 14 children (38%). The difference in sex, height, weight, total eosinophil count, serum IgF and test between EIA and Non-EIA were not significant (P>0.05). 2) In EIA group, %PEFR was changed from 109.56% to 83.56%, But in Non-EIA group, %PEFR was not changed before and after exercise loading test. 3) In EIA group, %FEV1 was changed from 90.91% to 74.87%. But in Non-EIA group, %FEV1 was not changed before and after exercise loading test. 4) In EIA group, %FVC changed from 91.83% to 75.35%. But in Non-EIA group, %FVC was not change before and after exercise loading test. 5) There was significant difference in pre-exercise specific airway resistance between EIA (6.7+/-1.7) and normal children (5.8+/-2.2)(p<0.05). In EIA group, %SRaw was changed from 115.7% to 161.2%. But in Non-EIA group, %SRaw was not changed before and after exercise loading test. 6) During the post-exercise observation period, increasement of SRaw was greater than changes in any other pulmonary function test. SRaw is the most sensitive test for the ditection of exercise induced airway obstruction is asthmatic children.
Adult
;
Airway Obstruction
;
Airway Resistance*
;
Asthma
;
Asthma, Exercise-Induced
;
Bronchial Spasm
;
Child*
;
Eosinophils
;
Humans
;
Peak Expiratory Flow Rate
;
Respiratory Function Tests
;
Running
2.A Case of Congenital T Cell Lymphoblastic Lymphoma.
Eun Sun YOO ; Young Mi HONG ; Kyung Hee KIM ; Hae Soo GYU ; Eun Chul CHUNG
Journal of the Korean Pediatric Society 1994;37(9):1296-1304
T cell lymphoblastic lymphoma is characterized by immature lymphoid cells that are indistinguishable from the lymphoblasts and prolymphocytes of acute lymphoblastic leukemia. Several characteristic clinical features of lymphoblastic lymphoma, with include a high male-to-female ratio, a relatively high incidence in older children and young adults, the frequent presence of mediastinal involvement at the time of diagnosis. Also, this disease is rapidly progressive, and early dissemination to the bone marrow, blood, and central nervous system leads to the evolution of a picture resembling a acute lymphoblastic leukemia. We have experienced a rare case of congenital T-cell lymphoblastic lymphoma in which 1/365 year old female newborn had generalized multiple irregular protruding mass on her body. On bone marrow biopsy, CSF analysis, ultrasonogram and whole body MRI studies. We found metastasized tumor mass to, orbit, abdominal cavity, bulva, skin, and lower extremities. Histopathologically, specimen from mass on the right thigh showed diffuse infiltration of poorly differentiated and immature lymphoid cells in the skelectal muscle and subcutaneous soft tissue. By immunophenotyping studies using anti T cell and B cell monoclonal antibody, these cells were reactive with UCHL-1, MB2, but unreactive with MB1, L26. Based on these findings, the lesion was diagnosed as lymphoblastic lymphoma of the T-cell type, which occurred congenitally. Most T cell lymphoblastic lymphoma are noted, but congenital case was not reported. So we report it with a brief review of literature.
Abdominal Cavity
;
Biopsy
;
Bone Marrow
;
Central Nervous System
;
Child
;
Diagnosis
;
Female
;
Humans
;
Immunophenotyping
;
Incidence
;
Infant, Newborn
;
Lower Extremity
;
Lymphocytes
;
Magnetic Resonance Imaging
;
Orbit
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
;
Skin
;
T-Lymphocytes
;
Thigh
;
Ultrasonography
;
Young Adult
3.The Effects of Trendelenburg Position and Intraabdominal CO2 Gas Insufflation on Cardiopulmonary System during Pelviscopic Surgery under General Anesthesia.
Won Ho LEE ; Ji Ae PARK ; Eun Mi LEE ; Mi Hwa CHUNG ; Rim Soo WON ; Hong Bae KIM
Korean Journal of Anesthesiology 1997;33(1):117-121
BACKGROUND: Pelviscopic techniques have rapidly increased in therapeutic procedures as well as diagnostic procedures because of the many benefits associated with much smaller incisions than traditional open techniques. But the deliberate pneumoperitoneum with carbon dioxide during pelviscopic surgery may cause some problems-hypercarbia, pneumomentum, subcutaneous or mediastinal emphysema, pneumothorax, hypoxemia, hypotension, cardiovascular collapse and cardiac dysrhythmia. METHOD: We observed the changes of blood pressure (systolic, mean, diastolic), pulse rate, PaCO2, PaO2, peak inspiratory airway pressure and expired tidal volume at 10 minute after induction of general anesthesia (control value), 30 minutes and 60 minutes after insufflation of CO2 and Trendelenburg position. RESULTS: The blood pressure, PaCO2 and peak inspiratory airway pressure were increased significantly than control values (p<0.05). The changes of pulse rate and expired tidal volume were not statistically significant in comparison to control values. The PaO2 was decreased significantly (p<0.05). CONCLUSION: To minimize the risk of CO2 retension and unstability of cardiovascular system during pelviscopy under the Trendelenburg position, we must monitor the vital signs and the arterial blood gas status continuously and carefully.
Anesthesia, General*
;
Anoxia
;
Arrhythmias, Cardiac
;
Blood Pressure
;
Carbon Dioxide
;
Cardiovascular System
;
Head-Down Tilt*
;
Heart Rate
;
Hypotension
;
Insufflation*
;
Mediastinal Emphysema
;
Pneumoperitoneum
;
Pneumothorax
;
Tidal Volume
;
Vital Signs
4.Effects of Soy Isoflavones Supplementation and Exercise on Urinary Calcium, Magnecium, Copper and Zinc Excretion in Postmenopausal Women.
Mi Eun YUN ; Da Hong LEE ; Mi Hyun KIM
The Korean Journal of Nutrition 2008;41(7):612-620
This study assessed the effects of soy isoflavones supplementation with exercise on urinary mineral (calcium, magnesium, copper, zinc) excretion as an index of bone resorption rates in 67 postmenopausal women. A total subjects were assigned to Isoflavone (90 mg/day) or placebo groups. These groups were further divided into groups that undergone a regular exercise or a rather sedentary state performing daily activity only. We conducted study eight week period. Result showed urinary zinc excretion was more significantly decreased in the isoflavone-sedentary group (-180.76 +/- 171.30 ug/day) than in the placebo-sedentary group (-31.23 +/- 146.60 ug/day), placebo-exercise group (40.93 +/- 193.44 ug/day) and isoflavione-exercise group (-1.21 +/- 160.61 ug/day) (p < 0.05), but no significant changes in the differences between the values of the pre and post study values in urinary calcium, magnesium and copper excretion. These results suggest that Isoflavone supplementation decrease urinary zinc excretion rate in postmenopausal subjects.
Bone Resorption
;
Calcium
;
Copper
;
Female
;
Humans
;
Isoflavones
;
Magnesium
;
Zinc
5.A Phenomenological Study on the Spontaneous Abortion Experiences of Women.
Korean Journal of Women Health Nursing 2017;23(2):63-77
PURPOSE: The purpose of this study was to explore essences and meaning in experiences of women who have had spontaneous abortion. METHODS: A phenomenological methodology was used for the study. A total of five women with the spontaneous abortion participated in the study. In-depth interviews were done for data collection, and the data were analyzed using Colaizzi's method. RESULTS: Five theme clusters, along with 32 sub-themes and 13 themes. The five theme clusters were: ‘Waiting and expecting pregnancy’, ‘Desire to overcome the spontaneous abortion’, ‘My baby makes me cry and laugh’, ‘My precious baby’, and ‘Want to hear with sympathy and talk with you’. CONCLUSION: The women who have had the spontaneous abortion experiences can prevent potential physical and psychological complications after miscarriage by getting education and intervention in nursing. Moreover, they may experience that negative factors of the spontaneous abortion can be turned into positive things through emotional support of family and medical teams.
Abortion, Spontaneous*
;
Data Collection
;
Education
;
Female
;
Humans
;
Methods
;
Nursing
;
Pregnancy
;
Qualitative Research
6.Comparison of Cine Magnetic Resonance Imaging with Doppler Echocardiography for the Quantative Evaluation of Tricuspid Regurgitation in Newborn.
Young Mi HONG ; Kyoung Hee KIM ; Eun Chul CHUNG ; Jung Soo SUH
Korean Circulation Journal 1995;25(1):44-49
BACKGROUND: Cine MR imaging has been found to bo a non-invasive technique in evaluation cardiac anatomy and cardiovascular function in a variety of cardiac diseases. The capability of this technique for quantatively estimating the severity of regurgitation has not been tested in newborns. The purpose of this study is to compare the degees of tricuspid regurgitation by echorcardiography with those by cine MRI, and verify the utility of MRi in evaluating tricuspid regurgitation. METHODS: Fifty-one newborns with tricuspid regurgitation were evaluated on the same day by echocardiography and cine MRI. Area and regurgitant fraction of area were estimated at four chamber view by two techniques. RESULTS: The area of tricuspid regurgitation was similar by two techniques. The correlation for the area(r=0.66, p<0.025) and the regurgitant area fraction(r=0.647, p<0.025) of tricuspid regurgitation obained by cine MRI with echocardiographic data was good. CONCLUSION: Cine MR imaging can provide quantative data estimating for evaluation of tricuspid regurgitation in newborns.
Echocardiography
;
Echocardiography, Doppler*
;
Heart Diseases
;
Humans
;
Infant, Newborn*
;
Magnetic Resonance Imaging
;
Magnetic Resonance Imaging, Cine*
;
Tricuspid Valve Insufficiency*
7.Extrapulmonary Silicosis: A case report.
Won Mi LEE ; Se Jin JANG ; Eun Kyung HONG ; Jung Dal LEE
Korean Journal of Pathology 1998;32(7):540-542
A case of extrapulmonary silicosis involving abdominal lymph nodes in a 62-year-old man is presented. The patient underwent subtotal gastrectomy and regional lymph nodes dissection for gastric adenocarcinoma of clinical stage III. On gross examination, two separate gastric adenocarcinomas and multiple enlarged lymph nodes mimicking metastatic lesion were noted. Microscopic examination of the enlaged lymph nodes revealed characteristic sclerohyaline silicotic nodules without metastatic adenocarcinoma. Chest roentgenogram showed diffusely scattered multiple tiny nodular lesions in the entire lung fields, particularly the posterior side of both upper lung fields. He had worked in a mine for 18 years and had been exposed to silica for 5 of those years. We report incidentally found, unusual case of extrapulmonary silicosis.
Adenocarcinoma
;
Gastrectomy
;
Humans
;
Lung
;
Lymph Nodes
;
Middle Aged
;
Silicon Dioxide
;
Silicosis*
;
Thorax
8.Molecular Epidemiology of Methicillin-resistant Staphylococcus aureus Outbreak by Plasmid Restriction Analysis.
Mi Ae LEE ; Eun Sook KANG ; Ki Sook HONG ; Wha Soon CHUNG
Korean Journal of Clinical Microbiology 1999;2(2):125-130
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) continues to be a major cause of nosocomial infection and a molecular typing is necessary for proper epidemiologic investigations of sources and moles of spread in an outbreak. An nosocomial outbreak of MRSA in a neonatal intensive care unit at Ewha Womans University Mokdong Hospital was suspected. To investigate the clonality of isolates and control the spread of nosocomial outbreak, we performed plasmid restriction analysis of MRSA isolates from patients and medical staffs. METHODS: We studied 7 MRSA strains (umbilicus 4, blood 1, urine 1 and pus 1) from patients in a neonatal intensive care unit and the MRSA strains from nares and hands surveillance cultures of 26 medical staffs (4 medical doctors and 22 nurses). All MRSA strains were tested for antimicrobial susceptibility and plasmic analysis after EcoRI restriction. We analyzed the plasmid patterns of MRSA isolated from patients and compared with those from medical staffs. RESULTS: Ten MRSA strains (from 7 nares and 3 hands) were isolated from surveillance cultures of 26 medical staffs. Seven out of 10 MRSA strains from medical staffs revealed identical pattern of antibiogram which was the same pattern in all 7 MRSA strains from seven patients. Plasmid restriction patterns were classified 6 groups from A to F showing 2-10 bands. Six out of 7 MRSA strains from the patients showed group A(A1 5, A31) and 5 out of 10 MRSA strains from the medical staffs showed group A(A1 1, A21, A32, A41) and remainders showed different plasmid restriction analysis patterns. CONCLUSIONS: These results suggest that plasmid restriction analysis is a rapid, inexpensive, and good discriminating molecular typing of MRSA outbreak and is useful for the epidemiologic investigation of MRSA outbreaks in the clinical laboratory.
Cross Infection
;
Disease Outbreaks
;
Female
;
Hand
;
Humans
;
Infant, Newborn
;
Intensive Care, Neonatal
;
Medical Staff
;
Methicillin Resistance*
;
Methicillin-Resistant Staphylococcus aureus*
;
Microbial Sensitivity Tests
;
Molecular Epidemiology*
;
Molecular Typing
;
Plasmids*
;
Suppuration
9.Prevalence Rates of and Related Factors to Constipation in Elementary School Students.
Mi Soon KIM ; Moo Sik LEE ; Baeg Ju NA ; Eun Young KIM ; Jee Young HONG
Korean Journal of Health Promotion 2013;13(3):93-98
BACKGROUND: This study was conducted to explore the prevalence of and the factors affecting constipation in elementary school students in urban and rural areas. METHODS: Study subjects were 585 grade 5 and 6 students. We conducted self-administered questionnaires during October, 2009. Outcome measure was the prevalence of constipation evaluated by the Rome III Diagnostic criteria for functional constipation. Independent variables were gender, grade, residence, mother's employment status, self-rated health status, number of family members, bowel movement habit, and health behavior (nutrition, exercise, and stress). RESULTS: The multiple logistic regression analysis showed that females, grade 5 students, those with working mothers, and those physically inactive reported having constipation significantly more often. CONCLUSIONS: Our study revealed that the female gender, increasing age, mother's employment status, and physical inactivity were risk factors for constipation in elementary school students. To improve bowel function in children, health education programs and school health promotion programs targeting healthy life habits should be implemented.
Child
;
Constipation*
;
Employment
;
Female
;
Health Behavior
;
Health Education
;
Humans
;
Logistic Models
;
Mothers
;
Outcome Assessment (Health Care)
;
Prevalence*
;
Risk Factors
;
School Health Services
;
Surveys and Questionnaires
10.Dermatophagoides farinae specific IgG-subclass antibody in allergic children.
Young Mi HONG ; Kyung Hyo KIM ; Eun Ae PARK ; Gyoung Hee KIM
Journal of the Korean Pediatric Society 1993;36(10):1351-1358
For determining the distribution of specific IgE and IgG-subclass antibodies and their role in allergic disorders, we measured the serum levels of specific IgG-subclass and IgE antibodies to Dermatophagoides farinae (Df) on 60 atopic children, aged between 8 to 12. All of them had positive skin test to Df, and was grouped into three: children with asthma only (group 1), with rhinitis (group 2), and with them together (group 3). Every data were compared with that of 47 nomal children. ELISA (for IgG and IgG-subclass) and RIA (for IgE) were used. The results are as following. 1) Specific IgE-antibody is significantly higher in all three allergic groups, compared with normal control group. But there was no significant difference between three allergy groups. 2) Specific IgG, IgG1, IgG2 IgG4-antibodies were higher than those in normal control group, but IgG3 was not significant. IgG1 and IgG2 were elevated particularly in patients with asthma and rhintis, but IgG4 was elevated in asthma group. 3) The linear correlation between specific IgE and IgG1-antibody was significant (r=0.286), but IgG4 did not have this correlation with IgE. In conclusion, the levels of specific IgE is essential for the diagnosis of allergies, and IgG1 and IgG4 seem to participate in allergic reactions with a different mechanism.
Antibodies
;
Asthma
;
Child*
;
Dermatophagoides farinae*
;
Diagnosis
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Hypersensitivity
;
Immunoglobulin E
;
Immunoglobulin G
;
Pyroglyphidae*
;
Rhinitis
;
Skin Tests