No abstract available.
Child ; Health Promotion ; Humans ; Immunization* ; Child Health

OBJECTIVE: It is known that risperidone induces weight gain moderately which has been previously considered of little clinical concern. And there was no specific effective treatment for atypical antipsychotics-induced weight gain. The study was performed to evaluate the effectiveness of topiramate as an weight-reducing medicine for schizophrenia patients with risperidone-induced weight gain. METHODS: Topiramate, 100-200 mg/day, was administered to 12 schizophrenia patients with risperidone-induced weight gain. Body weight and body mass index (BMI) were measured at baseline, 4-week and 8-week. Brief Psychatric Rating Scale (BPRS) and Positive And Negative Syndrome Scale (PANSS) were used to evaluate psychotic symptoms. RESULTS: Body weight and BMI were decreased significantly at 4-week and 8-week treatment compared to baseline (weight loss: 1.17+/-1.80 kg and 2.50+/-2.24 kg; BMI: -0.41+/-0.65 kg/m2 and -0.88+/-0.82 kg/m2 on 4-week and 8-week). Psychiatric symptoms were improved significantly in BPRS and PANSS. Adverse effects were showed such as fatigue, paresthesia, difficulty in concentration and diarrhea, which were mild and self-limited. CONCLUSION: It is suggested that topiramate have significant effects on patients with risperidone-induced weight gain. Randomized controlled study would be necessary in the near future.
Body Mass Index ; Body Weight ; Diarrhea ; Fatigue ; Humans ; Paresthesia ; Pilot Projects* ; Risperidone ; Schizophrenia ; Weight Gain*

OBJECTIVE: To evaluate whether the basal serum luteinizing hormone (LH) levels in the presence of normal serum follicle stimulating hormone (FSH) are useful as a prognostic indicator of ovarian response to controlled ovarian hyperstimulation (COH). METHODS: From January 1997 to January 1999, 91 infertile women with tubal factor who had undergone in vitro fertilization and embryo transfer (IVF-ET) were enrolled in the present study. COH was performed using long protocol of gonadotropin-releasing hormone (GnRH) agonist. All patients included in this study had blood samples drawn on cycle day 2 or 3 prior to COH for measurement of basal FSH and LH. Women who had other infertility factors or high basal FSH levels (> or = 8.5 mIU/ml) were excluded from this study. The results of COH and IVF-ET were compared between two groups according to the level of basal LH (low LH group [< 3mIU/ml] vs. control group [> or = 3mIU/ml]). RESULTS: Patient's characteristics were comparable in both groups except basal LH level. The number of ampules and duration of exogenous gonadotropins required were significantly higher in the low LH group than those in the control group (p<0.001; p<0.005, respectively). The number of follicles > or = 14mm diameter on the day of human chorionic gonadotropin (hCG) injection was significantly less in the low LH group than that in the control group (p<0.001). The serum estradiol level on the day of hCG injection was also significantly lower in the low LH group, with 1115.5 +/- 380.9 pg/ml compared with 1340.6 +/- 403.0 pg/ml in the control group (p<0.005). There were significantly lower numbers in oocytes retrieved, oocytes fertilized and embryos frozen in the low LH group than those in the control group (< 0.001; < 0.001; <0.005, respectively). However, there was no difference in the fertilization rate between the two groups. The clinical pregnancy rate per cycle seemed to be lower in the low LH group, but the difference did not achieve significance (26.2% vs 39.7%). There were no differences in the miscarriage rate and multiple pregnancy rate between the two groups. CONCLUSION: This study demonstrates that the low basal LH levels ( < 3 mIU/ml) could be predictive of low ovarian response to COH and poor IVF results.
Abortion, Spontaneous ; Chorionic Gonadotropin ; Embryo Transfer ; Embryonic Structures ; Estradiol ; Female ; Fertilization ; Fertilization in Vitro ; Follicle Stimulating Hormone ; Gonadotropin-Releasing Hormone ; Gonadotropins ; Humans ; Infertility ; Lutein* ; Luteinizing Hormone* ; Oocytes ; Pregnancy ; Pregnancy Rate ; Pregnancy, Multiple

PURPOSE: This study investigated the statistical methods and the results had reported correlation/regression analysis in the studies of Korean Journal of Women Health Nursing (KJWHN). METHODS: We reviewed 45 studies using correlation/regression analysis for the suitability of the statistical methods and the research purposes, the criteria for analysis of figures, tables and charts had published in the KJWHN from vol 13 (1) in 2007 to vol 15 (4) in 2009. RESULTS: Forty three studies were fitted to their statistical methodology and their research purposes. Eleven studies considered the minimum sample size. Fourteen regression studies used multiple regression and 12 studies used forward method for variable entry. Only one study among the 17 regression studies accomplished scatter plots and residuals examination. Sixteen studies in correlation studies and six studies in regression studies showed some errors in either the title, variables, category of figures, tables and charts. In the regression study, all reported R2 and beta values except one. CONCLUSION: It was found that there were still statistical errors or articulation errors in the statistical analysis. All reviewers need to be reviewed more closely for detecting errors not only during reviewing process of the manuscript but also periodic publication for the quality of this academic journal.
Female ; Humans ; Publications ; Regression Analysis* ; Sample Size ; Statistics as Topic ; Women's Health

PURPOSE: This study was done to evaluate the accuracy and adequacy of research studies reporting statistical testing for mean differences in studies of the Korean Journal of Women Health. METHODS: Among articles published in the journal from 2007 to 2009, 75 studies using t-test, chi2-test, and ANOVA were identified. The studies were evaluated using structured analysis format for adequacy of research title, accuracy of statistical methods and presentation styles, and errors in reported statistical outcomes. RESULTS: In this study, the research titles generally reflected the purpose of research and study designs. Thus the research titles were quite comprehensive. Also, there was compatibility between the research purpose and research design. Most important though, many errors were identified in the tables of results of the statistical analysis in articles published from 2004 to 2006. CONCLUSION: Over six years, 2004 to 2009, accuracy and adequacy of research studies has improved in many aspects. In order to enhance the completeness of the published papers and to be an internationally recognized nursing journal, close attention of the researchers, reviewers and editors is necessary to avoid errors and present adequate and accurate research.
Analysis of Variance ; Female ; Humans ; Research Design ; Women's Health

PURPOSE: This study was done to evaluate quality of reports of non-randomized controlled quasi-experimental study articles published in the Korean Journal of Women Health Nursing (KJWHN). METHODS: A search was done for experimental studies assessing intervention effects among all articles published in the KJWHNfrom 2008 to 2013. Original articles were reviewed and analyzed according to the 22 checklist items of the guidelines for Transparent Reporting for Evaluations with Non-randomized Designs (TREND). RESULTS: Thirty-five articles on experimental studies were identified. The evaluation of the quality of reporting in these experimental studies found that there was a wide variety in the level of satisfying the TREND checklist. In particular, according to TREND topics, low levels of reporting quality were found for "title & abstract (only for information on how units were allocated to the intervention)", "outcomes in methods", "assignment in methods", "blinding in methods", "recruitment in results", "baseline data in results", "interpretation in discussion (especially intervention mechanism and success or barriers), "generalizability in discussion". CONCLUSION: Results indicate that adherence to TREND guidelines varied in experimental studies published in the KJWHN suggesting the recommendation that for higher levels of complete reporting, TREND guidelines be used in reports on experimental studies.
Checklist ; Female ; Humans ; Clinical Trial* ; Methods ; Nursing Research ; Nursing* ; Research Design ; Women's Health*

PURPOSE: This research was aimed to analyze the reports of qualitative researches published in Korean Journal of Women Health Nursing (KJWHN). METHODS: Twenty qualitative researches using in-depth interviews or focus groups published in KJWHN during from 2002 to 2011 were selected for analysis. Selected reports were analyzed by consolidated criteria for reporting qualitative research (COREQ), which were a reporting guideline for qualitative researches, and consisted of thirty two items and three domains, i.e., (1) research team and reflexivity, (2) study design, and (3) data analysis and reporting. RESULTS: Personal characteristics related to credentials, gender and interviewer's bias or assumption were less reported than other items in the 1st domain. In the 2nd domain, descriptions such as a presence of non-participants, pilot test for interview guide development, and transcript return to participants were less reported than other items. In the 3rd domain, items related to number of data coder, participants checking of the finding, and clarity of minor themes were less reported than other items. CONCLUSION: It could be concluded that COREQ is a useful guideline for reporting of qualitative studies. From these results, we suggest that full items of COREQ should be considered and described when researchers report qualitative research.
Bias (Epidemiology) ; Female ; Focus Groups ; Humans ; Qualitative Research ; Reflex ; Statistics as Topic ; Women's Health

PURPOSE: This study s aim was to analyze literature using the identified key words of published literature within the Korean Journal of Womens Health Nursing from 2007~2009. The study explored the major subjects and research methodology used and evaluated the quality of this Journal articles. METHODS: Survey design using a structured analysis format was used for consistent evaluation of research subjects, type of research, research methodology, data analysis, along with comparing intervention research, theoretical framework, ethical consideration, and the implications. The frequency of the use of each keyword was classified by 8 domains. RESULTS: Ninety eight papers were analyzed altogether. Most of the subjects in these papers were women with 86.7% being quantitative research. In these studies, 76.5% used convenience sampling; 70.6% used a survey design whereas 23.5% used experimental design. Health related concepts (n=159) was mentioned the most among the 8 domains. The key words frequently used were women, depression, knowledge, quality of life, attitude, elderly, anxiety and stress in descending order. CONCLUSION: It can be concluded that most papers in this Journal during this time period addressed recent women's health issues. Also it showed this Journal and its literature has reached the indexing for Medline.
Abstracting and Indexing as Topic ; Aged ; Anxiety ; Depression ; Female ; Humans ; Quality of Life ; Research Design ; Research Subjects ; Statistics as Topic ; Women's Health

Globally, there have been a small number of donor cell leukemia cases reported but, to our knowledge, none have been reported in Korea until now. Donor cell leukemia is a rare though well-recognized complication that occurs after allogenic hematopoietic stem cell transplantation (allo-HSCT). Herein, we report the case of an 18-year-old woman who developed acute lymphoblastic leukemia originating from donor cells after allo-HSCT.
Adolescent ; Anemia, Aplastic* ; Bone Marrow Transplantation* ; Bone Marrow* ; Female ; Hematopoietic Stem Cell Transplantation ; Humans ; Korea ; Leukemia* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Tissue Donors*

Fibrous dysplasia is a benign, bony abnormality that is usually asymptomatic. A 41-year-old male with minimal symptoms presented at this hospital with abnormal findings incidentally seen in his ribs on the chest radiograph. A skeletal survey showed numerous, osteolytic lesions throughout multiple bones. Diagnostic processes for malignancy of undefined primary origin (MUO) were performed in order to identify the underlying primary neoplasm, although abnormal findings were not seen except for multiple bone lesions. A computed tomography guided bone biopsy was performed on his left rib. The final diagnosis was fibrous dysplasia. This case demonstrates that fibrous dysplasia should be considered in the differential diagnosis in young patients with multiple, osteolytic lesions and without a prior history suggesting malignancy.
Adult ; Biopsy ; Bone Neoplasms ; Diagnosis ; Diagnosis, Differential ; Fibrous Dysplasia, Polyostotic* ; Humans ; Male ; Neoplasm Metastasis* ; Radiography, Thoracic ; Ribs