No abstract available.
Child ; Health Promotion ; Humans ; Immunization* ; Child Health

OBJECTIVE: To evaluate whether the basal serum luteinizing hormone (LH) levels in the presence of normal serum follicle stimulating hormone (FSH) are useful as a prognostic indicator of ovarian response to controlled ovarian hyperstimulation (COH). METHODS: From January 1997 to January 1999, 91 infertile women with tubal factor who had undergone in vitro fertilization and embryo transfer (IVF-ET) were enrolled in the present study. COH was performed using long protocol of gonadotropin-releasing hormone (GnRH) agonist. All patients included in this study had blood samples drawn on cycle day 2 or 3 prior to COH for measurement of basal FSH and LH. Women who had other infertility factors or high basal FSH levels (> or = 8.5 mIU/ml) were excluded from this study. The results of COH and IVF-ET were compared between two groups according to the level of basal LH (low LH group [< 3mIU/ml] vs. control group [> or = 3mIU/ml]). RESULTS: Patient's characteristics were comparable in both groups except basal LH level. The number of ampules and duration of exogenous gonadotropins required were significantly higher in the low LH group than those in the control group (p<0.001; p<0.005, respectively). The number of follicles > or = 14mm diameter on the day of human chorionic gonadotropin (hCG) injection was significantly less in the low LH group than that in the control group (p<0.001). The serum estradiol level on the day of hCG injection was also significantly lower in the low LH group, with 1115.5 +/- 380.9 pg/ml compared with 1340.6 +/- 403.0 pg/ml in the control group (p<0.005). There were significantly lower numbers in oocytes retrieved, oocytes fertilized and embryos frozen in the low LH group than those in the control group (< 0.001; < 0.001; <0.005, respectively). However, there was no difference in the fertilization rate between the two groups. The clinical pregnancy rate per cycle seemed to be lower in the low LH group, but the difference did not achieve significance (26.2% vs 39.7%). There were no differences in the miscarriage rate and multiple pregnancy rate between the two groups. CONCLUSION: This study demonstrates that the low basal LH levels ( < 3 mIU/ml) could be predictive of low ovarian response to COH and poor IVF results.
Abortion, Spontaneous ; Chorionic Gonadotropin ; Embryo Transfer ; Embryonic Structures ; Estradiol ; Female ; Fertilization ; Fertilization in Vitro ; Follicle Stimulating Hormone ; Gonadotropin-Releasing Hormone ; Gonadotropins ; Humans ; Infertility ; Lutein* ; Luteinizing Hormone* ; Oocytes ; Pregnancy ; Pregnancy Rate ; Pregnancy, Multiple

OBJECTIVE: It is known that risperidone induces weight gain moderately which has been previously considered of little clinical concern. And there was no specific effective treatment for atypical antipsychotics-induced weight gain. The study was performed to evaluate the effectiveness of topiramate as an weight-reducing medicine for schizophrenia patients with risperidone-induced weight gain. METHODS: Topiramate, 100-200 mg/day, was administered to 12 schizophrenia patients with risperidone-induced weight gain. Body weight and body mass index (BMI) were measured at baseline, 4-week and 8-week. Brief Psychatric Rating Scale (BPRS) and Positive And Negative Syndrome Scale (PANSS) were used to evaluate psychotic symptoms. RESULTS: Body weight and BMI were decreased significantly at 4-week and 8-week treatment compared to baseline (weight loss: 1.17+/-1.80 kg and 2.50+/-2.24 kg; BMI: -0.41+/-0.65 kg/m2 and -0.88+/-0.82 kg/m2 on 4-week and 8-week). Psychiatric symptoms were improved significantly in BPRS and PANSS. Adverse effects were showed such as fatigue, paresthesia, difficulty in concentration and diarrhea, which were mild and self-limited. CONCLUSION: It is suggested that topiramate have significant effects on patients with risperidone-induced weight gain. Randomized controlled study would be necessary in the near future.
Body Mass Index ; Body Weight ; Diarrhea ; Fatigue ; Humans ; Paresthesia ; Pilot Projects* ; Risperidone ; Schizophrenia ; Weight Gain*

Fingertip amputation is a common traumatic injury which can be treated with revascularization therapy or composite grafting. This article reports two case studies showing the successful management of fingertip amputation using hyperbaric oxygen therapy (HBOT) and prostaglandin E1 (PGE1) treatment after composite grafting, where revascularization was not possible. HBOT was used to promote angiogenesis, improve oxygen transfer, and accelerate wound healing. At the same time, PGE1 was administered to control inflammation, stimulate cell proliferation, and promote tissue repair. These case reports offer effective approaches to treating fingertip amputation. The treatment strategy used in this study can be expected to improve patient outcomes and quality of life.

Fingertip amputation is a common traumatic injury which can be treated with revascularization therapy or composite grafting. This article reports two case studies showing the successful management of fingertip amputation using hyperbaric oxygen therapy (HBOT) and prostaglandin E1 (PGE1) treatment after composite grafting, where revascularization was not possible. HBOT was used to promote angiogenesis, improve oxygen transfer, and accelerate wound healing. At the same time, PGE1 was administered to control inflammation, stimulate cell proliferation, and promote tissue repair. These case reports offer effective approaches to treating fingertip amputation. The treatment strategy used in this study can be expected to improve patient outcomes and quality of life.

Fingertip amputation is a common traumatic injury which can be treated with revascularization therapy or composite grafting. This article reports two case studies showing the successful management of fingertip amputation using hyperbaric oxygen therapy (HBOT) and prostaglandin E1 (PGE1) treatment after composite grafting, where revascularization was not possible. HBOT was used to promote angiogenesis, improve oxygen transfer, and accelerate wound healing. At the same time, PGE1 was administered to control inflammation, stimulate cell proliferation, and promote tissue repair. These case reports offer effective approaches to treating fingertip amputation. The treatment strategy used in this study can be expected to improve patient outcomes and quality of life.

Fingertip amputation is a common traumatic injury which can be treated with revascularization therapy or composite grafting. This article reports two case studies showing the successful management of fingertip amputation using hyperbaric oxygen therapy (HBOT) and prostaglandin E1 (PGE1) treatment after composite grafting, where revascularization was not possible. HBOT was used to promote angiogenesis, improve oxygen transfer, and accelerate wound healing. At the same time, PGE1 was administered to control inflammation, stimulate cell proliferation, and promote tissue repair. These case reports offer effective approaches to treating fingertip amputation. The treatment strategy used in this study can be expected to improve patient outcomes and quality of life.

PURPOSE: This study was done to evaluate the accuracy and adequacy of research studies reporting statistical testing for mean differences in studies of the Korean Journal of Women Health. METHODS: Among articles published in the journal from 2007 to 2009, 75 studies using t-test, chi2-test, and ANOVA were identified. The studies were evaluated using structured analysis format for adequacy of research title, accuracy of statistical methods and presentation styles, and errors in reported statistical outcomes. RESULTS: In this study, the research titles generally reflected the purpose of research and study designs. Thus the research titles were quite comprehensive. Also, there was compatibility between the research purpose and research design. Most important though, many errors were identified in the tables of results of the statistical analysis in articles published from 2004 to 2006. CONCLUSION: Over six years, 2004 to 2009, accuracy and adequacy of research studies has improved in many aspects. In order to enhance the completeness of the published papers and to be an internationally recognized nursing journal, close attention of the researchers, reviewers and editors is necessary to avoid errors and present adequate and accurate research.
Analysis of Variance ; Female ; Humans ; Research Design ; Women's Health

PURPOSE: This research was aimed to analyze the reports of qualitative researches published in Korean Journal of Women Health Nursing (KJWHN). METHODS: Twenty qualitative researches using in-depth interviews or focus groups published in KJWHN during from 2002 to 2011 were selected for analysis. Selected reports were analyzed by consolidated criteria for reporting qualitative research (COREQ), which were a reporting guideline for qualitative researches, and consisted of thirty two items and three domains, i.e., (1) research team and reflexivity, (2) study design, and (3) data analysis and reporting. RESULTS: Personal characteristics related to credentials, gender and interviewer's bias or assumption were less reported than other items in the 1st domain. In the 2nd domain, descriptions such as a presence of non-participants, pilot test for interview guide development, and transcript return to participants were less reported than other items. In the 3rd domain, items related to number of data coder, participants checking of the finding, and clarity of minor themes were less reported than other items. CONCLUSION: It could be concluded that COREQ is a useful guideline for reporting of qualitative studies. From these results, we suggest that full items of COREQ should be considered and described when researchers report qualitative research.
Bias (Epidemiology) ; Female ; Focus Groups ; Humans ; Qualitative Research ; Reflex ; Statistics as Topic ; Women's Health

PURPOSE: This study was done to evaluate quality of reports of non-randomized controlled quasi-experimental study articles published in the Korean Journal of Women Health Nursing (KJWHN). METHODS: A search was done for experimental studies assessing intervention effects among all articles published in the KJWHNfrom 2008 to 2013. Original articles were reviewed and analyzed according to the 22 checklist items of the guidelines for Transparent Reporting for Evaluations with Non-randomized Designs (TREND). RESULTS: Thirty-five articles on experimental studies were identified. The evaluation of the quality of reporting in these experimental studies found that there was a wide variety in the level of satisfying the TREND checklist. In particular, according to TREND topics, low levels of reporting quality were found for "title & abstract (only for information on how units were allocated to the intervention)", "outcomes in methods", "assignment in methods", "blinding in methods", "recruitment in results", "baseline data in results", "interpretation in discussion (especially intervention mechanism and success or barriers), "generalizability in discussion". CONCLUSION: Results indicate that adherence to TREND guidelines varied in experimental studies published in the KJWHN suggesting the recommendation that for higher levels of complete reporting, TREND guidelines be used in reports on experimental studies.
Checklist ; Female ; Humans ; Clinical Trial* ; Methods ; Nursing Research ; Nursing* ; Research Design ; Women's Health*