1.Cases with Endometrial Polyp and Endocervical Polyp Associated With Tamoxifen Use.
Byung Hoon CHOE ; Eun Kyoung CHOI ; Young Tae KIM ; Jae Wook KIM ; Byung Woo PARK
Korean Journal of Obstetrics and Gynecology 2000;43(4):725-730
Tamoxifen is a nonsteroidal triphenylethylene delivative that has been widely used in the treatment of breast cancer. tamoxifen is indicated for the adjuvant treatment of breast cancer in women following total mastectomy or segmental mastectomy, breast irradiation and chemotherapy. tamoxifen has been shown to have significant benificial effect in the treatment of breast cancer patient as hormonal therapy. However ,there is mounting evidence that tamoxifen may affect other hormon sensitive organs, including the uterus and ovaries. An increased risk of endometrial polyps, endometrial hyperplasia and adenocarcinoma has been reported in tamoxifen treated women. We have met cases of endometrial polyp and endocervical polyp which were associated with tamoxifen use, after modified radical mastectomy for infilterating ductal carcinoma of breast . So we report these cases with the brief review of literatures.
Adenocarcinoma
;
Breast
;
Breast Neoplasms
;
Carcinoma, Ductal
;
Drug Therapy
;
Endometrial Hyperplasia
;
Female
;
Humans
;
Mastectomy, Modified Radical
;
Mastectomy, Segmental
;
Mastectomy, Simple
;
Ovary
;
Polyps*
;
Tamoxifen*
;
Uterus
2.CT findings of rounded atelectasis.
Chan Wha LEE ; Kyu Ok CHOE ; Jong Doo LEE ; Eun Kyoung HAN ; Woo Ick YANG
Journal of the Korean Radiological Society 1991;27(2):231-235
No abstract available.
Pulmonary Atelectasis*
3.Effect of Gl Cyclins Expression on Clinical Prognostic Parameters in Cervical Carcinoma.
Young Tae KIM ; Byung Hoon CHOE ; Jae Wook KIM ; Jae Hoong KO ; Eun Kyoung CHOI
Korean Journal of Gynecologic Oncology and Colposcopy 1999;10(3):233-241
Alterations in the expression of genes that control the cell cycle may be of critical importance in tumorigenesis and malignant transformation. The major regulatory events leading to cell proliferation occur in Gl phase of cell cycle, and the deregulated expression of Gl cyclins is related to oncogenesis. Cyclins Dl and E play important roles in the progression of cell through Gl phase of the cell cycle. Amplification and/or overexpression of the cyclin Dl gene and aberrant expression of cyclin E has been described in various forms of human cancer. However, the role of cyclins Dl and E in cervical cancer has been poorly defined. In this study, we examined the expression of cyclins Dl and E by Northern blot technique and the status of human papil- lomavirus(HPV) type 16 and 18 by polymerase chain reaction in 25 cases of cervical carcinoma to explore the relationship between cyclins Dl and E and cervical cancer. We found cyclin Dl expression showed down-regulated expression in cervical cancer but cyclin E expression was increased in cancer group. Other clinicopathological prognostic factors were not correlated with cyclins D1 and E expression. Further study based on larger numbers of cases with correlation of cyclins D1 and E status and survival data will be needed to elucidate the use of cyclin expressions as prognostic factor.
Blotting, Northern
;
Carcinogenesis
;
Cell Cycle
;
Cell Proliferation
;
Cyclin E
;
Cyclins*
;
Humans
;
Polymerase Chain Reaction
;
Uterine Cervical Neoplasms
4.Oxygen Consumption at Different Treadmill Speed and Grade in Athletes and Nonathletes.
Jeong Heui CHOE ; Hyeong Jin KIM ; Eun Kyoung YANG ; Yoon Yub PARK ; Jae Sik PARK
Korean Circulation Journal 1995;25(6):1175-1182
This study was aimed to elucidate the relationship between combinations of treadmill speed-grade and oxygen consumption(Vo2). Twenty athetic and 20 non-athletic male college students aged 19-24yr were employed to exercise on a treadmill using 4 speeds(4.02, 5.47, 6.76 and 8.05km/h) and 5 grades(0, 8, 12, 16 and 20%). A fixed speed was selected for each session with the grade increased every 3 min. The Vo2, heart rate, stride frequency and stride length were measured during the last min of each 3-min stage. Vo2increased linearly with increasing speed and grade showing significant multiple correlations in nonathletes(Vo2=3.64x+0.831y+0.031xy-7.03, R=0.98, P<0.01) and athletes(Vo2=3.48x+0.324y+0.112xy-5.74, R=0.99, P<0.01). Stride frequency and length tended to increase with increasing speed except for the transition from walking to runnig at 8.05Km/h at which the stride frequency ran up much higher with the stride length getting lower than at 6.76Km/h. Heart rate increased linearly with increasing Vo2. The rate of increase was higher during walking than during running. These results indicate that athletes have higher rate of increase in Vo2than nonathletes at near-maximal exercise and may be used as a guideline in predicting maximum oxygen comsumption and in prescribing exercise intensity.
Athletes*
;
Heart Rate
;
Humans
;
Male
;
Oxygen Consumption*
;
Oxygen*
;
Running
;
Walking
5.A Review of Improvements for Providing Safe and Secure Environments for Medical Treatment
A Reum CHOE ; Sung Eun KIM ; Kyoung Hee BAEK
Health Policy and Management 2019;29(2):105-111
On December 31, 2018, an incident occurred where a doctor was attacked and killed by a patient carrying a lethal weapon in the outpatients' clinic of the psychiatric department of a tertiary general hospital. The suspect was diagnosed with bipolar affective disorder (manic depressive disorder) and has been hospitalized and cared for in the psychiatric ward of this hospital. This incident illustrates the necessity of more active cures and therapeutic intervention for mental patients with intellectual developmental disorders who require treatment considering the fact that a radical outcome has been caused by such a patient. However, on the other hand, there is also a need for an approach and analysis from the perspective of crime prevention for all medical departments. The reason for this is that even a tertiary general hospital equipped with the largest human resources, medical devices, facilities, and so forth, is susceptible to violence. As for illegal actions perpetrated against health and medical service personnel in medical institutions, such as verbal abuse, assault, injury, etc. there have neither been understanding shown for the current extent of damage in detail, nor discussions of active institutional improvement related to the seriousness of the act. It can be said that violence in the field of medical treatment is a realm requiring serious discussion and appropriate remedial actions. This is because when such incidents take place, if a patient who is supposed to get treatment from the damaged health care provider is in an urgent situation or on the waiting list of serious cases, he or she could suffer serious damage caused by deprivation of treatment opportunity, or secondary damage might be caused to the patient and/or a guardian who can hardly have an opportunity to take action. Accordingly, in this review, we would like to help create the necessary conditions for both health and medical service personnel and patients/guardians, respectively, to provide and receive medical treatment in a more secure environment. Therefore, objective assessment of the institution and issues relating to this aforementioned incident and general cases of violence occurring in medical institutions, and by suggesting legal and institutional improvements and solutions.
Crime
;
Hand
;
Health Personnel
;
Hospitals, General
;
Humans
;
Mentally Ill Persons
;
Mood Disorders
;
Violence
;
Waiting Lists
;
Weapons
6.Children with COVID-19 after Reopening of Schools, South Korea
Eun Young KIM ; Boyeong RYU ; Eun Kyoung KIM ; Young-Joon PARK ; Young June CHOE ; Hye Kyung PARK ; Eun Kyeong JEONG
Pediatric Infection & Vaccine 2020;27(3):180-183
Purpose:
To describe pediatric coronavirus disease 2019 (COVID-19) cases after the reopening of schools in the Republic of Korea and their transmission routes.
Methods:
All case report forms and epidemiologic investigation forms for children aged 3–18 years reported as COVID-19 cases to the National Notifiable Disease Surveillance System from May 1 to July 12, 2020, were reviewed.
Results:
After the schools were reopened in May 2020, a total of 127 pediatric COVID-19 cases were confirmed until July 12. Of these, 59 children (46%) were exposed to severe acute respiratory syndrome coronavirus 2 through family and relatives, followed by 18 children (14%) through cram schools or private lessons, 8 children (6%) through multi-use facilities, and 3 children (2%) through school.
Conclusions
The present data do not suggest an increased risk of COVID-19 transmission in the context of stringent school-based infection prevention measures introduced across the country.
7.Children with COVID-19 after Reopening of Schools, South Korea
Eun Young KIM ; Boyeong RYU ; Eun Kyoung KIM ; Young-Joon PARK ; Young June CHOE ; Hye Kyung PARK ; Eun Kyeong JEONG
Pediatric Infection & Vaccine 2020;27(3):180-183
Purpose:
To describe pediatric coronavirus disease 2019 (COVID-19) cases after the reopening of schools in the Republic of Korea and their transmission routes.
Methods:
All case report forms and epidemiologic investigation forms for children aged 3–18 years reported as COVID-19 cases to the National Notifiable Disease Surveillance System from May 1 to July 12, 2020, were reviewed.
Results:
After the schools were reopened in May 2020, a total of 127 pediatric COVID-19 cases were confirmed until July 12. Of these, 59 children (46%) were exposed to severe acute respiratory syndrome coronavirus 2 through family and relatives, followed by 18 children (14%) through cram schools or private lessons, 8 children (6%) through multi-use facilities, and 3 children (2%) through school.
Conclusions
The present data do not suggest an increased risk of COVID-19 transmission in the context of stringent school-based infection prevention measures introduced across the country.
8.A Primary Neuroendocrine Tumor Mimicking a Thrombus in the Left Atrial Appendage
Myoung Kyoung KIM ; Sung Mok KIM ; Eun Kyoung KIM ; Dong Seop JEONG ; Yeon Hyeon CHOE
Journal of the Korean Radiological Society 2022;83(2):444-449
Most cardiac tumors are metastases, and primary cardiac tumors are rare; even among primary cardiac tumors, primary cardiac neuroendocrine tumors (NETs) are extremely rare. Herein, we report a case of a patient presenting a left atrial mass without past medical history. Because of the location and movement of the mass, as well as the patient's cerebral infarction episode, the mass was initially suspected to be a thrombus. However, the mass was surgically diagnosed as NET.
9.Three-Dimensional Printed Model of Partial Anomalous Pulmonary Venous Return with Biatrial Connection
Myoung Kyoung KIM ; Sung Mok KIM ; Eun Kyoung KIM ; Sung-A CHANG ; Tae-Gook JUN ; Yeon Hyeon CHOE
Journal of the Korean Radiological Society 2020;81(6):1523-1528
Partial anomalous pulmonary venous return (PAPVR) is a rare congenital cardiac anomaly that can be difficult to detect and often remains undiagnosed. PAPVR is diagnosed using non-invasive imaging techniques such as echocardiography, CT, and MRI. Image data are reviewed on a 2-dimensional (D) monitor, which may not facilitate a good understanding of the complex 3D heart structure. In recent years, 3D printing technology, which allows the creation of physical cardiac models using source image datasets obtained from cardiac CT or MRI, has been increasingly used in the medical field. We report a case involving a 3D-printed model of PAPVR with a biatrial connection. This model demonstrated separate drainages of the right upper and middle pulmonary veins into the lower superior vena cava (SVC) and the junction between the SVC and the right atrium, respectively, with biatrial communication through the right middle pulmonary vein.
10.Three-Dimensional Printed Model of Partial Anomalous Pulmonary Venous Return with Biatrial Connection
Myoung Kyoung KIM ; Sung Mok KIM ; Eun Kyoung KIM ; Sung-A CHANG ; Tae-Gook JUN ; Yeon Hyeon CHOE
Journal of the Korean Radiological Society 2020;81(6):1523-1528
Partial anomalous pulmonary venous return (PAPVR) is a rare congenital cardiac anomaly that can be difficult to detect and often remains undiagnosed. PAPVR is diagnosed using non-invasive imaging techniques such as echocardiography, CT, and MRI. Image data are reviewed on a 2-dimensional (D) monitor, which may not facilitate a good understanding of the complex 3D heart structure. In recent years, 3D printing technology, which allows the creation of physical cardiac models using source image datasets obtained from cardiac CT or MRI, has been increasingly used in the medical field. We report a case involving a 3D-printed model of PAPVR with a biatrial connection. This model demonstrated separate drainages of the right upper and middle pulmonary veins into the lower superior vena cava (SVC) and the junction between the SVC and the right atrium, respectively, with biatrial communication through the right middle pulmonary vein.