Sleep disorders such as insomnia, obstructive sleep apnea (OSA), and restless legs syndrome (RLS) are very common disorders and may cause significant burden in terms of individual as well as societal aspects. Sleep insufficiency from such sleep disorders may cause deleterious effects on daily work life and may be associated with other major medical or psychiatric disorders including cardiovascular disease, diabetes mellitus, depression, and anxiety disorder. Various motor or occupational accident may result from the sleep problems. In addition, recent researches provide the method to evaluate the lost productivity time in terms of absenteeism and presenteeism. Moreover, several studies on cost-effectiveness of treatment of sleep disorders show that it is cost-effective.
Absenteeism ; Accidents, Occupational ; Anxiety Disorders ; Cardiovascular Diseases ; Depression ; Diabetes Mellitus ; Efficiency ; Restless Legs Syndrome ; Sleep Apnea, Obstructive ; Sleep Wake Disorders ; Sleep Initiation and Maintenance Disorders

No abstract available.
Lung Diseases, Interstitial*

No abstract available.
Hypertension* ; Renin*

No abstract available.
Hair ; Scalp

No abstract available.
Nephrolithiasis* ; Uric Acid*

A clinical observation was made on the non-visualizing kidney of the in-patient in the Department of Urology, Capital Armed Forces General Hospital during the period from September, 1976 to December, 1981 and the following results were observed. 1. Of 1287 cases hospitalized, IVP was performed on 292 cases. Among these, 36 cases revealed non- visualizing kidney giving a rate of 12.3%. 2. The sex ratio between male and female was 8:1 and age distribution ranged from 1 to 66 years. 3. The clinical symptoms and signs were hematuria, flank pain, frequency, lower abdominal pain, and abdominal palpable mass in order. 4. The causes of non-visualizing kidney was classified as renal parenchymal and obstructive disease. Renal tuberculosis (9 cases) was the most frequent cause among the disease of parenchymal origin, and the calculus disease of the urinary track (5 cases) and hydronephrosis not caused by calculi (5 cases) were the most frequent cause among the disease of obstructive origin. 5. Surgery was performed in 29 cases (80.1%) and remaining 7 cases were managed conservatively.
Abdominal Pain ; Age Distribution ; Arm ; Calculi ; Female ; Flank Pain ; Hematuria ; Hospitals, General ; Humans ; Hydronephrosis ; Kidney* ; Male ; Sex Ratio ; Tuberculosis, Renal ; Urology

No abstract available.
Breast* ; Humans

BACKGROUND: Myocardial ischemia in human hypertension and in various animal models of hypertension may be due to abnormal maximal coronary vasodilator reserve and disturbaces of coronary vasomotion. The vascular reactivity defects in hypertension have been associated with the defective endothelium and sympathetic neural activation. However, such abnormalities in hypertension need to be elucidated. In the present study the effectsof cardiac ischemia reperfusion on coronary circulation, intramyocytic adenylates and purine nucleosides were examined in Langendorff-perfused Sprague Dawley rat (SD) and spontaneously hypertensive rat (SHR) hearts. Coronary venous and cardiac lactate and cardiac pyruvate were also measured. It should be noted that in the regulation of coronary flow the intrinsic flow autoregulation is highly variable due to coexisting metabolic flow control, and that natural coronary flow and cardiomyocytic energy state are normally reciprocally related in perfused heart. METHODS: For the Langendorff heart perfusion, bicarbonate perfusion buffer (pH 7.40+/-0.02,37degrees C) was equilibrated with 95% O2 : 5% CO2 and contained 5mM glucose (+5U/1 insulin) and 2mM pyruvate as energy-yielding substrates. Global hypoperfusion ischemia was induced by lowering coronary perfusion pressure of 100 to 40 cmH2O, followed by 20 min reperfusion. RESULTS: During the ischemia and reperfusion, metabolic acidosis and enhanced venous lactate output in SHR were observed with increases in coronary vascular resistance and myocardial oxygen consumption.In addition, coronary reactive hyperemia during reperfusion was depressed. Although ischemia-induced increase in combined adenosine plus inosine were abolished during prolonged reperfusion, SD still exhibited coronary vasodilation. The depressed reactive hyperemia in SHR was associated with decreases in cardiac adenosine triphosphate (ATP) pool and creatine phosphate/inorganic phosphate (CrP/Pi) ratio and an increase in cardiac lactate/pyruvate ratio. CONCLUSION: This abnormal vascular reactivity during ischemia and reperfusion in SHR may be in part due to an alteration in the cardiac energy state and hence to a mismatch between myocardial metabolic demand and supply.
Acidosis ; Adenosine ; Adenosine Triphosphate ; Animals ; Coronary Circulation ; Creatine ; Endothelium ; Glucose ; Heart* ; Homeostasis ; Humans ; Hyperemia ; Hypertension ; Inosine ; Ischemia ; Lactic Acid ; Models, Animal ; Myocardial Ischemia ; Oxygen ; Perfusion* ; Purine Nucleosides ; Pyruvic Acid ; Rats ; Rats, Inbred SHR* ; Reperfusion ; Vascular Resistance ; Vasodilation

No abstract available.
Coronary Circulation* ; Heart* ; Rats, Inbred SHR*

This study was done to identify the effectiveness of a proper positioning on musculoskeletal complication on patient with Stroke by using a quasi-experimental study. A total of 18 patients were selected as a subject from June 1st to October 31th 1998 who had been hospitalized at Intensive Care Units in K medical center. A experimental group consists of 8 patients who were given proper positioning every two hours. A control group consists of 10 patients who were given traditional positioning. The collected data were analyzed by SPSS windows including chi-test(Fisher's exact method), Wilcoxon Rank Sum test and McNemar test. The result of this study was summerized as follows: 1) The experimental group with proper positioning has shown lower shoulder pain score, dorsiflexion contracture score, Shoulder subluxation score and higher Range of Motion and than the control group. 2) The experimental group with proper positioning has shown lower muscle pain score and edema score than the control group, but it was not statistically significant. Therefore, proper positioning could be applied as an independent nursing intervention for patients on Stroke in order to facilitate rehabilitation.
Contracture ; Edema ; Humans ; Intensive Care Units ; Myalgia ; Nursing ; Range of Motion, Articular ; Rehabilitation ; Shoulder ; Shoulder Pain ; Stroke*