Bronchioloalveolar carcinoma may present with a variety of radiographic and clinical appearances. The authors reviewed the radiographs of 17 patients with pathologically proven bronchioloalveolar carcinoma, retrospectively. Seven cases were of the localized form. Among the seven five showed a localized mass and two showed localized consolidation. Ten cases were of the diffuse form. Among the ten, three showed diffuse nodules, two showed diffuse consolidation, and five showed a combined pattern of nodules and consolidations. Progression of disease was observed in 9 patients. In these cases, localized forms progressed to a diffuse forms and nodular patterns progressed to a consolidation pattern. Seven cases of the diffuse form were given antituberculous medications on hospital admission. In summary, bronchioloalveolar carcinoma has varied radiographic patterns, and often mimicks other pulmonary diseases such as pulmonary tuberculosis.
Adenocarcinoma, Bronchiolo-Alveolar* ; Humans ; Lung Diseases ; Retrospective Studies ; Tuberculosis, Pulmonary

Ligamentous injury of the knee which could be easily occur in sports or traffic accidents resulted in more and severe disability than that of other joints. Rupture of the anterior cruciate ligament which restrain hyperextension, excessive rotation and anterior motion of tibia on femur is the most frequent and significant injury of the knee. Its treatment and clinical significance is one of the most controversial issue and its incidence tends to increase. From 1983 to 1985, modified Scott operation were performed on 10 patients at the department of orthopedic surgery, Chung Ang university hospital. Following results are obtained. 1. No limitation of range of motion of the knee was developed. 2. Intra-articular fixation by use of pull-out wire was done and special consideration was done for the site of fixation on tibia plateau and method of dilatation of posterior capsule. 3. Of the ten patients, nine had negative anterior drawer test, postoperatively.
Accidents, Traffic ; Anterior Cruciate Ligament ; Dilatation ; Femur ; Humans ; Incidence ; Joints ; Knee ; Ligaments ; Methods ; Orthopedics ; Range of Motion, Articular ; Rupture ; Sports ; Tibia

Human sparganosis is one of the fhost common tissue parasitoses caused by helminthes in Korea. Human sparganosis is found most frequently in subcutaneous or adipose tissue of the abdominal wall, thoracic wall and inguinal region, it is rarely found in the orbital cavity, abdominal cavity, brain, breast, or lower extremities. We experienced one ease of sparganosis which developed into the thigh and popliteal area in combination with avascular necrosis of the femoral head. The case is a 59 years old male. The patient had the history of eating raw meat as a tonic food 3 years ago. The presenting symptom was left hip joint pain. We confirmed the sparganosis in microscopic findings of worms and by immunologic serum studies. The avascular necrosis of the femoral head was detected with plain roentgenography and magnetic resonance imaging. Many spargana were removed from the lesions by surgical excision. Two of them were alive, and others had degenerated or calcified. The life cycle and route of infestation of sparganosis were discussed briefly and related literatures were reviewed.
Abdominal Cavity ; Abdominal Wall ; Adipose Tissue ; Brain ; Breast ; Eating ; Head* ; Helminths ; Hip Joint ; Humans ; Korea ; Life Cycle Stages ; Lower Extremity ; Magnetic Resonance Imaging ; Male ; Meat ; Middle Aged ; Necrosis* ; Orbit ; Radiography ; Sparganosis* ; Thigh* ; Thoracic Wall

The purpose of the study was to evaluate the effect of commonly used orthopaedic material, stainless steel (SS) screw (2.7xlOmm, Synthes) and titanium (Ti) screw (2.7x10mm, Synthes), on bacterial adherence and infection. The bacteria used for this study was Staphylococcus epidermidis for its ability of adherence. For in vitro assay, screws of each material were placed into test tube containing 107 colony forming unit (CFU) of S. epidermidis in trypticase soy broth for 18 hours. Following incubation, each screws were treated either with trypsin or with an ultrasonic cleaner. For in vivo assay, we inoculated 5x107 CFU of S. epidermidis into the proximal tibial metaphysis of the rabbits, and then inserted Ti screw on the right side and SS screw on the left side. The amount of in vitro adherence of S. epidermidis was greater for SS screw than for Ti screw. Especially following trypsin treatment, SS groups yielded significantly higher bacterial counts than Ti group, respectively (1.4x105 CFU vs 2.8x104 CFU, p<0.05). We found a significantly higher bacterial count after use of SS screw than after Ti screw in rabbits in vivo assay also. Trypsin treatment for identifying biofilm embedded bacteria from implanted metal may be useful in the diagnosis of infection. Ti screw appears to have biocompatibility to inhibit bacterial adherence compared with SS screw in the rabbit tibial model.
Bacteria ; Bacterial Load ; Biofilms ; Diagnosis ; Rabbits ; Stainless Steel ; Staphylococcus epidermidis ; Stem Cells ; Titanium ; Trypsin ; Ultrasonics

Concerns have been raised about the potential for hardware failure in interlocking nails and screws especially with small diameter nail. Existing techniques for removing broken interlocking screws can involve trephine over-cutting of the screws, which requires wide bone exposure and creates larger stress risers by enlarging the original screw hole. We present this new technique for removal of broken screws of 2 femoral interlocking nails and 6 tibia interlocking nails. This Steinmann pin ""punch"" technique is to drive the screws through the opposite cortex and soft tissue for removal through a small stab wound. The rationale of this technique is based on the less holding power of the interlocking screw which is not only a machinary screw but also placed on the metaphyseal portion.
Tibia ; Wounds, Stab

Local deposition of antibiotics has become increasing popular in the management of open fractures or osteomyelitis, and several substances have been employed as the vehicle for delivery. Although the elution characteristics of some substances have been documented, a comparative study of the characteristics of the commonly used substances were performed in order to establish the clinical indications for particular vehicles. Carriers were prepared, which were human iliac cancellous bone, bovine cancellous bone matrix(Lubboc?), absorbable gelatin sponge(Gelfoam?), fibrin glue(Beriplast? P) and polymethylmethacrylate(CMW?) for elution characteristics of vancomycin. The each carriers were immersed on the 20 ml of PBS and then obtained the samples for analysis of concentration of vancomycin at first, second, third, fourth, fifth, sixth, fourteenth, twenty-first, twenty-eighth day after immersion. The assay technique was fluorescent polarization immunoassay(Abbott, Dallas, Texas, U.S.A.). Nearly 50% of vancomycin was released from human iliac cancellous bone, Lubboc? and fibrin glue during the first 3 days, and negligible after first week. Gelatin sponge produced high local concentration of vancomycin during the first week. PMMA eluted the only 6% of vancomycin during the first day and trace amount detected as long as 4 weeks. There are significant statistical difference among carriers at second and fourth week(ANOVA test, P < 0.05). The authors considered that human iliac cancellous bone, Lubboc? ,Gelfoam? and fibrin glue may be best employed when brief antibiotic coverage is required, whereas PMMA may be better suited for long-term coverage.
Anti-Bacterial Agents ; Fibrin ; Fibrin Tissue Adhesive ; Fractures, Open ; Gelatin ; Gelatin Sponge, Absorbable ; Humans ; Immersion ; In Vitro Techniques ; Osteomyelitis ; Pharmacokinetics ; Polymethyl Methacrylate ; Porifera ; Texas ; Vancomycin

The treatment of Achilles tendon rupture is controversial between surgical repair and conservative cast treatment. Until the 1970s, treatment of Achilles tendon rupture was predominantly surgical repair, but Lea and Smith reported better results in conservative treatment of Achilles tendon rupture and other authors confirmed their good results with cast treatment. This study was attempted to compare the subjective and objective results between operative and conservative treatments of patients with ruptured Achilles tendon. In a retrospective study, 30 Patients with ruptured Achilles tendon were analyzed from January 1990 to May 1994. 15 patients were surgically repaired(group I), and 15 patients were treated with gravity equines short leg walking cast(group II), Patient's subject satisfaction, duration from trauma to normal activity level, plantar flexion power, tendinous healing state checked by ultrasonography, and complications were compared, and following results were obtained. 1. All patients satisfied with conservative treatment in group II, while 12 patients were satisfied with operative treatment in group I. 2. The plantar flexion power of injured side was 89% in group I, 87% in group II comparing with uninjured side. 3. Ultrasonographically, mean thickness and ruptured midportion thickness in group II was thicker than those of group I(8.7, 10.6 vs 9.2, 13.2mm), but focal sonolucent area which indicates incomplete healing was observed more in group II than in group I(4 vs 2). 4. Three patients had complications in group I-1rerupture, 1 infection and 1 sural nerve injury.
Achilles Tendon ; Gravitation ; Humans ; Leg ; Retrospective Studies ; Rupture ; Sural Nerve ; Ultrasonography ; Walking

No abstract available.
Pregnancy* ; Round Ligament of Uterus*

We have expressed GFP in Sf9 and Bm5 cells or Bombyx by larvae by using Ac-Bm hybrid virus capable of replicating in both Bm5 and Sf9 cells. Genomic DNA of Ac-Bm hybrid virus expressing P-galactosidase was cotransfected with baculovirus transfer vector containing GFP gene, pBacPAK-GFP in Sf9 cells. The Ac-Bm hybrid virus harboring GFP was named as Ac-Bm hybrid virus-GFP. The Ac-Bm hybrid virus-GFP-infected insect cells were easily selected by detecting the emission of GFP from each well of cell culture dish on the UV illuminator. GFP produced by Ac-Bm hybrid virus-GFP in Sf9 and Bm5 cells or B. mori larvae was confirmed by SDS-PAGE and Western blot analysis using GFP antibody. In addition, B. mori larvae infected with Ac-Bm hybrid virus-GFP was apparently appeared fluorescence from the whole body at 5 days postinoculation. The fluorescence of GFP from the hemolymph and fat body of B. mori larvae infected with Ac-Bm hybrid virus-GFP was also observed by fluorescence microscope. In conclusion, our results demonstrated that in baculovirus expression vector system, use of Ac-Bm hybrid virus have an additional advantage of expanded host range for producing recombinant proteins.
Animals ; Baculoviridae ; Blotting, Western ; Bombyx* ; Cell Culture Techniques ; DNA ; Electrophoresis, Polyacrylamide Gel ; Fat Body ; Fluorescence ; Hemolymph ; Host Specificity ; Insects ; Larva* ; Recombinant Proteins ; Sf9 Cells ; Spodoptera*

No abstract available.
Pierre Robin Syndrome*